GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	March 20, 2024
ECODAB	April 1, 2019

Displaying entries **226 - 250** of **597** in total

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Pathway Name	Protein Name ▼	UniProt ID	Gene Symbol	Organism
GABA synthesis, release, reuptake and degradation	Complexin DnaJ homolog subfamily C member 5 homolog Glutamate decarboxylase Heat shock 70 kDa protein cognate 4 Protein ROP Rab3 interacting molecule, isoform F Ras-related protein Rab-3 Synaptobrevin Synaptosomal-associated protein 25 Synaptosomal-associated protein Synaptotagmin 1 Syntaxin-1A Vesicular GABA transporter	A0A0B4K6M2 A1Z9M6 P11147 P18489 P20228 P21521 P25228 P36975 Q03751 Q07327 Q24547 Q8IPM8 Q9VH76	CG7301 CG7305 CG7321 CG8394.2 Csp DRIM DmRIM Dmel\CG33547 Dmel\CG8394 Dmel\CG9474 Gad Gad1 Glb Hsc4 Hsc70-4 RIM Rab3 Rim Rop SNAP-24 SNAP-25b SNAP24 Snap24 Snap25 Snap25b Syb Syt1 Syx1A UNC-10/RIM VGAT VIAAT Vgat cpx cs1 dm-Rim rim rim-1 syt syx-1A vGAT	Drosophila melanogaster (fruit fly)
CRMPs in Sema3A signaling	Collapsin response mediator protein Cyclin-dependent kinase 5 activator Cyclin-dependent kinase 5 homolog MIP07328p Plexin A, isoform A Protein kinase shaggy Putative glycogen synthase kinase-3 homolog Semaphorin 2b, isoform D Semaphorin-1A Semaphorin-2A Tyrosine-protein kinase Fer Tyrosine-protein kinase Src64B	A0A0B4KG38 P00528 P18106 P18431 P48609 P83101 Q24322 Q24323 Q7KK54 Q8IPQ2 Q9V3H5 Q9V491	BcDNA:GH03186 BcDNA:GM05237 BcDNA:HL02693 CG30322 CG4383 CRMP Cdk5 Cdk5-alpha Cdk5a Cdk5alpha D-Plex A D-p35 D-semaIII DHP DPlexA Dmel\CG11081 Dmel\CG1411 Dmel\CG33960 Dmel\CG5387 Dmel\CG6446 Dp35 Dsema-I EP(3)3238 EP3238 FER Fps85D HD-179 P35 Plex1 PlexA PlexA1 PlexinA Pyd2 Sema 1b Sema III Sema-1a Sema-1b Sema-1b-RB Sema-2a Sema-2b Sema1a Sema1b Sema2a Sema2b SemaIIB Src1 Src64B crmp dCdk5alpha fps gsk3 gskt l(3)83Ba lincRNA.927 p25 p35 p35-21C p35-31C plex plex A plexA pyd2 sema-2b sema-III sema1b sema2b semaphorin-like sgg zw3	Drosophila melanogaster (fruit fly)
Collagen chain trimerization	Collagen alpha-1(IV) chain Multiplexin, isoform R	M9ND55 P08120	CG14822 CG33171 CG8645 CG8647 COL18A1 CT14872 Cg25C Col4a1 DCg1 Dmel\CG42543 Dmp Mp dmp mp multiplexin	Drosophila melanogaster (fruit fly)
Collagen biosynthesis and modifying enzymes	Collagen alpha chain CG42342 Collagen alpha-1(IV) chain Dorsal-ventral patterning protein tolloid GH21475p Glycosyltransferase 25 family member Multiplexin, isoform R Procollagen-lysine,2-oxoglutarate 5-dioxygenase Protein disulfide-isomerase Protein tolkin Serine protease inhibitor 28Dc Serine protease inhibitor 77Ba Serpin 77Bb Viking, isoform A	B7Z0K8 M9ND55 P08120 P25723 P54399 Q0E8C8 Q8IPK4 Q9VC47 Q9VLU4 Q9VMV5 Q9VPH9 Q9VTH0 Q9VWB4	1209 6072 CG14822 CG31915 CG33171 CG42342 CG6266 CG8645 CG8647 COL18A1 CT14872 CT25584 Cg25C Col4a1 ColIV ColIValpha2 Coll IV Coll IValpha2 DCg1 DmColA2 Dmel\CG16858 Dmel\CG42543 Dmel\CG6289 Dmel\CG6663 Dmp Mp Pdi Plod Spn28D Spn28Dc Spn77 Spn77Ba Spn77Bb Spn77Bc Vkg VkgC alpha(IV)2/vkg col4a2 colIV coll-IV coll. IV collagen-IV dmp l(2)01209 mp multiplexin tld tlr tlr-1 tok veg vkg	Drosophila melanogaster (fruit fly)
Transcription regulation of cwo gene	Circadian locomoter output cycles protein kaput Protein cycle Transcription factor cwo	O61734 O61735 Q9VGZ5	CLOCK Clk PAS1 cwo cyc jrk	Drosophila melanogaster (fruit fly)
Transcription activation by CLK:CYC and repression by VRI	Circadian locomoter output cycles protein kaput GH23983p PAR domain protein 1-delta Protein cycle	O61734 O61735 Q24217 Q9VMS4	CLOCK Clk DM1 DM16 DM32 Dmel\CG14029 Dmel\CG17888 PAS1 PDP PDP-1epsilon PDP1 PDP1 epsilon PDP1epsilon Pdp-1 Pdp1 Pdp1 epsilon Pdp1&e:gr Pdp1e Pdp1epsilon VRI Vri anon-WO0140519.206 argo cyc jf23 jrk l(2)25Db l(2)jf23 mat(2)ea-G mat(2)earlyRS32 mel_pdp1 mel_vri pdp pdp1 pdp1epsilon vri	Drosophila melanogaster (fruit fly)
Dephosphorylation of PER	Circadian locomoter output cycles protein kaput Discs overgrown protein kinase Period circadian protein Protein cycle Protein phosphatase PP2A 55 kDa regulatory subunit Protein timeless Serine/threonine protein phosphatase 2A regulatory subunit Serine/threonine-protein phosphatase PP2A 65 kDa regulatory subunit Serine/threonine-protein phosphatase PP2A	O61734 O61735 O76324 P07663 P23696 P36179 P36872 P49021 Q9VB23	0318/07 B56-2 BEST:LD02456 BcDNA.LD34343 BcDNA:LD34343 CLOCK Clk Dmel\CG5643 EP3559 LD02456 PAS1 PP2-AB PP2A PP2A-B' PP2A[B'-2] PP2a Pp2A-28D Pp2A-29B Pp2A-85F WDB Wdb Widerborst aar cyc dB56-2 dPP2A dPP2A-B56-2 dbt dco jrk l(3)S031807 mts per tim tws wbd wdb	Drosophila melanogaster (fruit fly)
Transcription repression by PER and activation by PDP1	Circadian locomoter output cycles protein kaput Discs overgrown protein kinase GH23983p PAR domain protein 1-delta Period circadian protein Protein cycle Protein timeless	O61734 O61735 O76324 P07663 P49021 Q24217 Q9VMS4	CLOCK Clk DM1 DM16 DM32 Dmel\CG14029 Dmel\CG17888 PAS1 PDP PDP-1epsilon PDP1 PDP1 epsilon PDP1epsilon Pdp-1 Pdp1 Pdp1 epsilon Pdp1&e:gr Pdp1e Pdp1epsilon VRI Vri anon-WO0140519.206 argo cyc dbt dco jf23 jrk l(2)25Db l(2)jf23 mat(2)ea-G mat(2)earlyRS32 mel_pdp1 mel_vri pdp pdp1 pdp1epsilon per tim vri	Drosophila melanogaster (fruit fly)
ERK/MAPK targets	Chromosomal serine/threonine-protein kinase JIL-1 Mitogen-activated protein kinase ERK-A Mitogen-activated protein kinase p38a Mitogen-activated protein kinase p38b Putative mitogen-activated protein kinase 14C Ribosomal protein S6 kinase II, isoform A Serine/threonine-protein phosphatase PP2A 65 kDa regulatory subunit Serine/threonine-protein phosphatase PP2A Well-rounded, isoform B	O61443 O62618 P23696 P36179 P40417 P83100 Q8IN89 Q9V3I5 Q9VR61	B' B'/PR61 B56-1 BcDNA:GM05554 CG 7913 CG7901 D-RSK Dmel\CG17596 Dmel\CG7913 ERKa JIL-1 MAPK Mpk2 PP2A PP2A B' PP2A-B PP2A-B' PP2A[B'-1] Pp2A-28D Pp2A-29B RSK Rsk S6KII S6kII Wrd anon-WO0118547.420 dB56-1 dPP2A dPP2A-B56-1 dRSK dRsk i234 ign mts p38a p38b p38c pp2A-B' rl rsk rsk2 wrd	Drosophila melanogaster (fruit fly)
NCAM signaling for neurite out-growth	Chromosomal serine/threonine-protein kinase JIL-1 Cyclic AMP response element-binding protein B Growth factor receptor-bound protein 2 Karst, isoform E Mitogen-activated protein kinase ERK-A Protein son of sevenless Ras-like protein 1 Spectrin alpha chain Spectrin beta chain Tyrosine-protein kinase Src64B Tyrosine-protein phosphatase Lar protein-tyrosine-phosphatase	A1ZAB3 A8JNJ6 P00528 P08646 P13395 P16621 P26675 P40417 Q00963 Q08012 Q9V3I5 Q9VWW0	CT18044 CrebB CrebB-17A DPTP52F Dmel\CG12008 Dmel\CG18243 E(sev)2B ERKa Grb2 JIL-1 Karst Kst Lar MAPK PTP52F Ptp52F Ptp52F-RB Ras1 Ras85D SPEC-A Sos Spec-b Spec-beta[[H]] Src1 Src64B alpha-Spec beta-Spec beta-Spectrin betaH betaH-Spec betaH-spectrin betaHS betaHSpec beta[[H]] beta[[H]]-SPEC beta[[H]]-Sp beta[[H]]-Spec beta[[H]]-Spectrin beta[[H]]spectrin beta[[Heavy]]spectrin beta[[heavy]]-Spec beta[[heavy]]-Spectrin beta[[heavy]]spectrin betah-Spec drk kst l(3)01318 ptp52F rl	Drosophila melanogaster (fruit fly)
PRC2 methylates histones and DNA	Chromatin assembly factor 1 p55 subunit Escl, isoform A Histone H2A.v Histone H2A Histone H2A Histone H2B Histone H3.3A Histone H3.3B Histone H3 Histone H4 Histone-lysine N-methyltransferase E(z) Jumonji, AT rich interactive domain 2 Polycomb protein Su(z)12 Zinc finger protein jing	C0HL66 C0HL67 P02283 P02299 P08985 P42124 P84040 P84051 Q24572 Q4AB57 Q7KHG2 Q9NJG9 Q9VKD5 Q9VT00	CG5202-PA Caf1 Caf1-55 Dmel\CG33853 Dmel\CG33856 Dmel\CG33859 Dmel\CG3654 Dmel\CG5202 E(z) ESC ESC-LIKE ESC1 ESCL Escl H2AvD H2a H4 H4r His2A His2A:CG31618 His2A:CG33808 His2A:CG33814 His2A:CG33817 His2A:CG33820 His2A:CG33823 His2A:CG33826 His2A:CG33829 His2A:CG33832 His2A:CG33835 His2A:CG33838 His2A:CG33841 His2A:CG33844 His2A:CG33847 His2A:CG33850 His2A:CG33853 His2A:CG33856 His2A:CG33859 His2A:CG33862 His2A:CG33865 His2Av His2AvD His2B His2B:CG17949 His2B:CG33868 His2B:CG33870 His2B:CG33872 His2B:CG33874 His2B:CG33876 His2B:CG33878 His2B:CG33880 His2B:CG33882 His2B:CG33884 His2B:CG33886 His2B:CG33888 His2B:CG33890 His2B:CG33892 His2B:CG33894 His2B:CG33896 His2B:CG33898 His2B:CG33900 His2B:CG33902 His2B:CG33904 His2B:CG33906 His2B:CG33908 His2B:CG33910 His3 His3.3A His3.3B His3:CG31613 His3:CG33803 His3:CG33806 His3:CG33809 His3:CG33812 His3:CG33815 His3:CG33818 His3:CG33821 His3:CG33824 His3:CG33827 His3:CG33830 His3:CG33833 His3:CG33836 His3:CG33839 His3:CG33842 His3:CG33845 His3:CG33848 His3:CG33851 His3:CG33854 His3:CG33857 His3:CG33860 His3:CG33863 His3:CG33866 His4 His4:CG31611 His4:CG33869 His4:CG33871 His4:CG33873 His4:CG33875 His4:CG33877 His4:CG33879 His4:CG33881 His4:CG33883 His4:CG33885 His4:CG33887 His4:CG33889 His4:CG33891 His4:CG33893 His4:CG33895 His4:CG33897 His4:CG33899 His4:CG33901 His4:CG33903 His4:CG33905 His4:CG33907 His4:CG33909 His4r JARID2 Jarid2 KMT6 Su(z)12 dJARID2 dJmj djmj escl jarid2 jing l(3)j2B8 rhumba	Drosophila melanogaster (fruit fly)
Transcriptional Regulation by E2F6	Chromatin assembly factor 1 p55 subunit E3 ubiquitin-protein ligase RING1 Enhancer of polycomb-like protein Escl, isoform A FI06908p G9a, isoform B GEO03726p1 Histone-lysine N-methyltransferase E(z) Lethal (3) 73Ah, isoform A Optomotor-blind-related-gene-1, isoform A Polycomb group protein Psc Polycomb protein Sfmbt Polycomb protein Su(z)12 Polyhomeotic distal, isoform A Polyhomeotic-proximal chromatin protein Protein max Serine/threonine-protein kinase grp Transcription factor Dp Transcription factor E2f1	A0A0B4KFP2 M9PGH7 O61661 P35820 P39769 P42124 P91664 Q24318 Q24572 Q27368 Q9NJG9 Q9VB08 Q9VK33 Q9VKD5 Q9VV77 Q9W215 Q9W396 Q9W3F4 Q9W523	CG5202-PA Caf1 Caf1-55 DROZFP Dm-ORG-1 Dmel\CG11202 Dmel\CG12190 Dmel\CG2995 Dmel\CG3895 Dmel\CG4195 Dmel\CG5202 Dmel\CG7041 Dmel\CG7776 Dp E(PC) E(Pc) E(z) E2f E2f1 EG:BACN25G24.3 EG:BACR37P7.2 EHMT ESC ESC-LIKE ESC1 ESCL Escl G9a GH05739 GH14582 HP1 HP1B HP1b HP1b-RA Hp1b I(3)73Ah III KMT6 L(3)73Ah Max Org-1 PH PH-d PHD Ph Ph-d PhD Psc RYBP Rybp Sce Sfmbt Su(z)12 anon-48Ac cab65850 G9a Dm dG9a dRYBP drybp e(Pc) e(pc) escl grp hp1b l(2)28-28-12 l(3)02540 l(3)133.18 l(3)73Ah org-1 org1 ph ph-D ph-d ph-p ph[D] ph[d] phd phm rybp	Drosophila melanogaster (fruit fly)
G0 and Early G1	Chromatin assembly factor 1 p55 subunit Cyclin-dependent kinase 2 G1/S-specific cyclin-E G2/mitotic-specific cyclin-A Histone deacetylase HDAC1 LD06557p LD07342p Lin-52, isoform A Protein lin-54 homolog RE32990p Retinoblastoma family protein Serine/threonine-protein kinase minibrain Transcription factor Dp Transcription factor E2F2	A1Z9E2 O77051 P14785 P23573 P49657 P54733 Q24318 Q24472 Q24572 Q7K159 Q94517 Q9VF04 Q9W482 Q9W542	86E4.4 Caf1 Caf1-55 Cdk2 CycA CycE Dmel\CG15119 Dmel\CG15929 Dmel\CG3480 Dmel\CG5083 Dp E2f2 EG:86E4.4 HDAC1 Lin-52 Lin52 Mip130 Mip130/TWIT Mip130/Twt Mip40 RB RBF2 RBf2 Rbf Rbf2 Rpd3 TWIT Twit cdc2c dLIN-52 dLin-52 dLin52 dlin-52 dlin52 lin-52 mip120 mip130 mip40 mnb p40 rbf2 twit	Drosophila melanogaster (fruit fly)
Regulation of PTEN gene transcription	Chromatin assembly factor 1 p55 subunit Chromodomain-helicase-DNA-binding protein 3 Chromodomain-helicase-DNA-binding protein Mi-2 homolog E3 ubiquitin-protein ligase RING1 Escl, isoform A GH04846p GH16429p GTP-binding protein Rheb homolog Histone deacetylase HDAC1 Histone-lysine N-methyltransferase E(z) Homeotic protein spalt-major Late endosomal/lysosomal adaptor and MAPK and MTOR activator 5 Metastasis associated 1-like, isoform D Methyl-CpG binding domain protein-like, isoform C Polycomb group protein Pc Polycomb group protein Psc Polycomb protein Scm Polycomb protein Su(z)12 Polyhomeotic distal, isoform A Polyhomeotic-proximal chromatin protein Protein LST8 homolog Ragulator complex protein LAMTOR1 Ragulator complex protein LAMTOR2 homolog Ragulator complex protein LAMTOR3 homolog Ragulator complex protein LAMTOR4 homolog Raptor, isoform B Repressor of RNA polymerase III transcription MAF1 Serine/threonine-protein kinase mTor Simjang, isoform E Transcription factor hamlet	A0A0B4KG70 A0A0B4KGZ0 M9PF79 O16102 O96824 O97159 P26017 P35820 P39769 P39770 P42124 Q24572 Q7K519 Q7PL26 Q8I7Z8 Q94517 Q9NJG9 Q9V8I2 Q9VB08 Q9VHA0 Q9VHJ4 Q9VJD2 Q9VK45 Q9VKD5 Q9VND8 Q9VW73 Q9VZL6 Q9W328 Q9W437 Q9W523	4320 BcDNA:RE59545 CG14184-RB CG5202-PA CG7983 CG8000 CR41604 Caf1 Caf1-55 Chd3 DROZFP Dm Mbd2/3 DmMbd2/3 Dmel\CG11968 Dmel\CG14184 Dmel\CG14812 Dmel\CG2244 Dmel\CG32067 Dmel\CG3895 Dmel\CG40196 Dmel\CG4320 Dmel\CG5202 Dmel\CG8208 Dmel\CG8707 E(z) EG:131F2.3 EG:BACN25G24.3 ESC ESC-LIKE ESC1 ESCL Escl Gtr1 Gtr2 HBXIP HDAC1 KMT6 Lamtor1 Lamtor2 Lamtor3 Lamtor4 Lamtor5 Lst8 MBD-like MBD2 MBD2-3 MBD2/3 MBD3 MTA MTA-like MTA1 MTA1-like Maf1 Mi-2 PH PH-d PHD Pc Ph Ph-d PhD Psc Rag Rag A RagA RagA-B RagA/B RagC RagC-D Raptor Rheb Rpd3 SIMJ Sce Scm Su(z)12 Tor anon-WO0118547.361 anon-WO0118547.633 dHBXIP dMBD-like dMBD2/3 dMTA dMTA-1 dMTA1-like dMaf1 dMbD2/3 dRAPTOR dRagA dRagB dRagC dRap dRaptor dp18 dp66 escl ham l(3)01814 l(3)j4A5 l(3)rN672 mTor p120 p18 p66 p66/68 p66/68-like ph ph-D ph-d ph-p ph[D] ph[d] phd phm rag ragA ragC raptor raptor/CG4320 sal salm simj	Drosophila melanogaster (fruit fly)
SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion	Chondrocyte-derived ezrin-like domain containing protein, isoform G MIP07328p Phosphatidylinositol 4-phosphate 5-kinase 59B, isoform G Plexin A, isoform A Rhea, isoform B Semaphorin 2b, isoform D Semaphorin-1A Semaphorin-2A Tyrosine-protein kinase Src64B	A0A0B4KG38 A0A6M3Q9L5 A8JQT5 P00528 Q24322 Q24323 Q7KK54 Q9V491 Q9VSL8	BcDNA:AT26639 BcDNA:GH03186 BcDNA:GM05237 BcDNA:RH50880 CDEP CG1283 CG17281 CG2008 CG30322 CG31536 CG34306 CG4383 CT21159 Cdep D-Plex A D-semaIII DPlexA Dmel\CG11081 Dmel\CG33960 Dmel\CG3682 Dmel\CG44193 Dmel\CG6446 Dmel\CG6831 Dsema-I PI4P5K PIP5K 59B PIP5K59B Plex1 PlexA PlexA1 PlexinA Rhea Sema 1b Sema III Sema-1a Sema-1b Sema-1b-RB Sema-2a Sema-2b Sema1a Sema1b Sema2a Sema2b SemaIIB Src1 Src64B Talin Tln cdep dPIP5K dPIP5K59B dpip5k i23 lincRNA.927 plex plex A plexA rhea sema-2b sema-III sema1b sema2b semaphorin-like talin tendrils	Drosophila melanogaster (fruit fly)
Choline catabolism	Choline transporter-like 1 GH11762p Sarcosine dehydrogenase aldehyde dehydrogenase (NAD(+))	A1ZAZ2 Q8SXQ1 Q9VY05 Q9VZE7	ALDH7A1 Aldh7A1 CT26924 Ctl1 Dmel\CG6385 Dmel\CG9512 Dmel\CG9629 Sardh sardh	Drosophila melanogaster (fruit fly)
Transport of bile salts and organic acids, metal ions and amine compounds	Choline transporter-like 1 Choline transporter-like 2 High-affinity choline transporter 1 RH04535p	Q9VAP3 Q9VE46 Q9VXV4 Q9VZE7	ChT Ctl1 Ctl2 Dmel\CG11655	Drosophila melanogaster (fruit fly)
Acetylcholine Neurotransmitter Release Cycle	Choline O-acetyltransferase Complexin High-affinity choline transporter 1 Liprin-alpha, isoform E Protein ROP RIM-binding protein, isoform F Rab3 interacting molecule, isoform F Ras-related protein Rab-3 Synaptobrevin Synaptosomal-associated protein 25 Synaptosomal-associated protein Synaptotagmin 1 Syntaxin-1A Unc-13, isoform E Vesicular acetylcholine transporter	A0A0B4JDC9 A0A0B4K6M2 H9XVP2 M9PCD4 O17444 P07668 P18489 P21521 P25228 P36975 Q07327 Q24547 Q8IPM8 Q9VE46 Q9VH76	CG14867 CG31302 CG5143 CG5152 CG7301 CG7305 CG7321 ChAT ChT Cha DLiprin DLiprin-alpha DRBP DRIM DUNC-13 Dliprin-alpha DmRIM Dmel\CG11199 Dmel\CG2999 Dmel\CG33547 Dmel\CG43073 Dmel\CG9474 Dunc-13 Dunc13 LIP LIP.1 LIP1 LPR Liprin Liprin-alpha Munc-13 Munc-13/UNC-13 RBP RIM Rab3 Rbp Rim Rop SNAP-24 SNAP-25b SNAP24 Snap24 Snap25 Snap25b Syb Syt1 Syx1A UNC-10/RIM UNC-13 UNC-13-B UNC13A UNC13B Unc-13 Unc13 Unc13A Unc13B VAChT cpx cs1 dUNC-13 dUnc-13 dm-Rim drbp drunc13 dunc-13 l(4)ry16 lip-alpha liprin liprin-alpha lpr oos rbp rim rim-1 rim-bp syt syx-1A unc unc-13	Drosophila melanogaster (fruit fly)
MAPK6/MAPK4 signaling	Cdc42 homolog ETV5-related protein Ets96B Forkhead box protein O Ras-related protein Rac1 Serine/threonine-protein kinase Pak Taiman, isoform G non-specific serine/threonine protein kinase	A0A0B4KGS4 M9ND53 P40792 P40793 Q8MRW5 Q95V55 Q9VI13	58/2 Afx CG18494 Cdc42 D-Pak3 DAIB1 DPAK DPAK3 DPak3 DmPAK3 DmTai DmTaiman Dmel\CG13109 Dmel\CG14895 Dpak1 Dpak3 EP(2)2630 Ets96B NEST:bs13g05 PAK-3 PAK3 PaK3 Pak Pak3 Rac1 RacA TAI Tai Taiman anon-WO0118547.285 bs13g05.y1 dPAK3 dpak3 foxo l(2)01351 l(2)k05802 l(2)k05809 pak3 tai	Drosophila melanogaster (fruit fly)
RHOJ GTPase cycle	Cdc42 homolog EG GTPase-activating protein CdGAPr LD20667p Pi3K21B, isoform B Rho GTPase-activating protein 100F Rho GTPase-activating protein 190 Rho GTPase-activating protein 68F Rho GTPase-activating protein Graf Trio, isoform A Uncharacterized protein, isoform A Uncharacterized protein, isoform B	A1ZAQ3 A1ZAQ4 O46094 P40793 Q7KTZ2 Q7KVD1 Q9V9S7 Q9VIS1 Q9VPI9 Q9VTU3 Q9VX32 X2JDY8	0368/10 0959/14 1372/03 1386/06 BEST:LD36950 CG15612 CG15613 CG9208 CdGAPr Cdc42 DTrio Dm zir Dmel\CG11376 Dmel\CG15611 Dmel\CG18214 Dmel\CG2699 Dmel\CG30456 Dmel\CG3573 Dp60 EG:86E4.5 FBgn 31216 Graf M89 Ocrl P60 PI(3)K PI3 kinase PI3K PI3K-p60 PI3K-reg PI3K21B PI[[3]]K Pi3K Pi3K21B Pi3Kp60 Pi3k21B RhoGAP100F RhoGAP68F RhoGAPp190 Syd-1 TRIO Trio UNC-73/Trio Zir anon-EST:Posey54 dOCRL dOcrl dP60 dPI3K dTrio deltap60 docrl dp60 droPIK57 l(3)036810 l(3)6D104 l(3)S036810 l(3)S095914 l(3)S137203 l(3)S138606 l(3)S[1372/3] l(3)S[1386/06] l(3)trio ocrl p60 p85 trio	Drosophila melanogaster (fruit fly)
CDC42 GTPase cycle	Cdc42 homolog Chondrocyte-derived ezrin-like domain containing protein, isoform G Crossveinless c, isoform C Dynamin associated protein 160, isoform D Ephexin, isoform D FI04035p FI17866p1 FI24033p1 GTPase-activating protein CdGAPr Guanine nucleotide-binding protein subunit alpha homolog LD16419p LD20667p LD43457p Pebble, isoform B Pi3K21B, isoform B Protein still life, isoform SIF type 1 Protein vav RalA-binding protein 1 Rho GTPase activating protein at 15B, isoform C Rho GTPase activating protein at 16F, isoform E Rho GTPase activating protein at 19D, isoform D Rho GTPase activating protein at 1A, isoform E Rho GTPase activating protein at 5A, isoform A Rho GTPase activating protein at 71E, isoform D Rho GTPase-activating protein 100F Rho GTPase-activating protein 190 Rho GTPase-activating protein 68F Rho GTPase-activating protein 92B Rho GTPase-activating protein Graf Rho GTPase-activating protein conundrum Rho guanine nucleotide exchange factor 2, isoform D Rho guanine nucleotide exchange factor 3, isoform L Rho-type guanine nucleotide exchange factor, isoform F Trio, isoform A Uncharacterized protein, isoform A Uncharacterized protein, isoform A Uncharacterized protein, isoform B Uncharacterized protein, isoform C Zizimin, isoform K	A1Z9I5 A1ZAN6 A1ZAQ3 A1ZAQ4 A1ZBA1 A8DZ19 A8JQT5 A8JR05 B7Z058 M9ND00 M9PCG3 M9PHU0 P25157 P40793 P91621 Q0E938 Q7K4E0 Q7KTZ2 Q7KVD1 Q8IQ97 Q8T0G4 Q9NHV9 Q9V9S7 Q9VDE9 Q9VDG2 Q9VDS5 Q9VIS1 Q9VPI9 Q9VTU3 Q9VVC6 Q9VW59 Q9VX32 Q9VX92 Q9W0S2 Q9W4A9 X2JC00 X2JCF3 X2JDY8 X2JEI9	0083/20 0293/09 0368/10 0542/03 0959/14 13345 1372/03 1386/06 1412 38C.40 ARHGEF7 AcGAP BCR BEST:LD36950 BcDNA:AT26639 BcDNA:GH03693 BcDNA:GH05095 BcDNA:LD07615 BcDNA:RH50880 BcDNA:RH71439 C- GAP C-GAP CDEP CG10412 CG10416 CG12183 CG1225 CG12432 CG1283 CG13881 CG13882 CG13883 CG14060 CG14845 CG14846 CG14847 CG14848 CG14849 CG15612 CG15613 CG15819 CG16980 CG17617 CG17960 CG18430 CG2008 CG30115-RE CG31319 CG31330 CG31536 CG34306 CG3799 CG40453 CG42377 CG42378 CG5503 CG6630 CG7396 CG8480 CG8557 CG9208 CTR CdGAPr Cdc42 Cdep CrGAP Cv-c DAP-160 DAP160 DRacGAP DRhoGEF DRhoGEF2 DTrio Dap160 Dap160/intersectin Dm zir Dm ziz Dmel\CG10043 Dmel\CG1099 Dmel\CG11376 Dmel\CG13345 Dmel\CG1412 Dmel\CG15611 Dmel\CG18214 Dmel\CG2699 Dmel\CG30115 Dmel\CG30440 Dmel\CG30456 Dmel\CG3208 Dmel\CG32149 Dmel\CG3421 Dmel\CG34389 Dmel\CG40494 Dmel\CG42533 Dmel\CG42665 Dmel\CG43658 Dmel\CG43976 Dmel\CG44193 Dmel\CG4937 Dmel\CG6424 Dmel\CG7122 Dmel\CG7823 Dmel\CG8114 Dmel\CG9635 Dp60 DrhoGEF DrhoGEF2 DrhoGEF3 DrtGEF ECT2 EG:23E12.2 EG:23E12.5 Ect-2 Exn Exn-RD FBgn 31216 GEF GEFmeso GH05095 Gef2 Graf M89 P60 PBL PI(3)K PI3 kinase PI3K PI3K-p60 PI3K-reg PI3K21B PI[[3]]K Pbl Pbl/Ect2 Peb Pi3K Pi3K21B Pi3Kp60 Pi3k21B Pix RG2 RacGAP RacGAP50C RacGAP50c RacGap RacGap50C Rho-GEF2 Rho/RacGEF RhoGAP RhoGAP-50C14 RhoGAP-71E1 RhoGAP100F RhoGAP15B RhoGAP16F RhoGAP19D RhoGAP1A RhoGAP5A RhoGAP68F RhoGAP71E RhoGAP88C RhoGAP92B RhoGAP93B RhoGAP93B-RA RhoGAPp190 RhoGDI RhoGEF RhoGEF2 RhoGEF3 RhoGF2 RhoGap71E RhoGef2 Rlip RoGAP71E RtGEF Su(Rho1)2B Syd-1 T2 TRIO TUM Trio Tum Tumbleweed UNC-73/Trio Vav Vilse Zir Ziz acGAP anon-EST:Posey54 anon-WO0118547.96 anon-WO0153538.32 anon-WO0153538.33 anon-WO0153538.34 anon-WO0172774.22 anon-WO0172774.25 beta-PIX betaPIX cdep conu cta cv-c dP60 dPI3K dPIX dPix dRhoGEF dRhoGEF2 dTrio dap160 deltap60 dp60 dpix droPIK57 eon exn gap20 i23 i249 l(2)04291 l(3)036810 l(3)06951 l(3)09645 l(3)6D104 l(3)S036810 l(3)S095914 l(3)S137203 l(3)S138606 l(3)S[1372/3] l(3)S[1386/06] l(3)j6B9 l(3)trio noncoding_4110 p160 p60 p85 pbl pix racGAP50 racGAP50C racGAP50c rhoGAP1A rhoGAP88C rhoGEF rhoGEF2 rhoGEF3 rhogap71e rhogef2 rtGEF shar sif trio tum tum-RA vilse	Drosophila melanogaster (fruit fly)
Activation of Matrix Metalloproteinases	Cathepsin L Furin-like protease 1, isoforms 1/1-X/2 Matrix metalloproteinase 1, isoform C Matrix metalloproteinase-2 RH50269p Tissue inhibitor of metalloproteinase	P26016 Q8MPP3 Q95029 Q9VH14 Q9VJD7 Q9W122	Cp1 Dm1-MMP Dmel\CG4859 Dmel\CG6639 Fur1 MMP MMP-1 MMP1 MMp1 Mmp 1 Mmp-1 Mmp1 Mmp2 SPH93 Timp c-SPH93 cSPH93 dMMP1 dm1-MMP dmmp1 fs(2)50Ca l(2)k04809 mmp-1 mmp1	Drosophila melanogaster (fruit fly)
MHC class II antigen presentation	Cathepsin B1, isoform A Cathepsin L GH19763p LD36817p Peptidase A1 domain-containing protein Putative cysteine proteinase CG12163 RH39096p Uncharacterized protein	A1ZAU4 Q7K0S6 Q95029 Q9VEK4 Q9VHA5 Q9VKY4 Q9VN93 Q9VY87	BEST:GH19547 CB CG-10992 CG12163 CG4847-RD CTSB1 CathB Cp1 CtsB CtsB1 CtsK2 CtsL2 CtsL4 Dmel\CG10992 Dmel\CG4847 Dmel\CG5367 Dmel\CG5860 Dmel\CG6347 Dmel\CG9427 FBgn0038506 anon-EST:ParkEST132 fs(2)50Ca	Drosophila melanogaster (fruit fly)
Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding	Casein kinase II subunit alpha Casein kinase II subunit beta G protein alpha q subunit Gbeta5 Guanine nucleotide-binding protein subunit alpha Guanine nucleotide-binding protein subunit alpha Guanine nucleotide-binding protein subunit beta-1 Guanine nucleotide-binding protein subunit beta-2 Guanine nucleotide-binding protein subunit gamma-1 Guanine nucleotide-binding protein subunit gamma-e Guanine nucleotide-binding protein subunit gamma LP21163p Phosducin-like protein T-complex protein 1 subunit alpha T-complex protein 1 subunit beta T-complex protein 1 subunit delta T-complex protein 1 subunit epsilon T-complex protein 1 subunit eta T-complex protein 1 subunit gamma T-complex protein 1 subunit theta T-complex protein 1 subunit zeta Uncharacterized protein, isoform B	A0A0B4K838 M9PHI8 P08181 P08182 P12613 P23625 P26308 P29829 P38040 P48605 Q0E9A7 Q7K3J0 Q7KKI0 Q8MQV5 Q9NFZ3 Q9VHL2 Q9VK69 Q9VUR7 Q9VXA3 Q9VXQ5 Q9W392 Q9W3J1	BcDNA.GM12270 BcDNA:GM12270 BcDNA:SD21019 CCT-1 CCT1 CCT2 CCT3 CCT4 CCT5 CCT6 CCT7 CCT8 CG15844 CG32543 CG7095 CG7650 Cask-II-a Cask-II-b Cct2 Cct4 Cct5 Cct6 Cct7 Cctg CkIIalpha CkIIbeta Dmel\CG10763 Dmel\CG17760 Dmel\CG30054 Dmel\CG42450 Dmel\CG43324 Dmel\CG5525 Dmel\CG7033 Dmel\CG8231 Dmel\CG8258 Dmel\CG8351 Dmel\CG8439 Dmel\CG9108 G-beta-5 G1 GNAQ/11/14 GNB5 G[[beta5]] G[[beta]] Galpha Galpha49b Galphaq Gb13F Gb76C Gbe Gbeta Gbeta 5 Gbeta13F Gbeta5 Gbeta76C Gbetae Gbetagamma Ggamma1 Ggamma30A Ggammae Gq Gqalpha L(1)g0022 Q7K3J0_DROME Q8IRM8_DROME Q9VHL2_DROME Q9VK69_DROME Q9VXQ5_DROME Q9W392_DROME RGS7 RSG7 Rcd3 SD02216p T-cp1 T-cp1eta TCP-1 TCP-1-zeta TCP-1beta TCP-1epsilon TCP-1theta TCP-1zeta TCP1-beta TCP1-delta TCP1-epsilon TCP1-eta TCP1-theta TCP1-zeta TCP1beta TCP1eta TCP1zeta TCPeta TCPzeta Tcp-1 Tcp-1-eta1 Tcp-1-zeta Tcp-1delta Tcp-1eta Tcp-1zeta Tcp1-beta Tcp1-delta Tcp1-epsilon Tcp1-theta cct4 cct5 cct8 dGqalpha dRGS7 dgq l(1)G0022 l(1)G0027 l(1)G0057 l(2)03996 l(2)06444 tcp-1eta tcp1eta	Drosophila melanogaster (fruit fly)
Activation of SMO	Casein kinase I isoform alpha G protein-coupled receptor kinase 1 Protein smoothened	P32865 P54367 P91682	CKI CkIalpha Gprk-1 Gprk1 smo	Drosophila melanogaster (fruit fly)

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