GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	March 20, 2024
ECODAB	April 1, 2019

Displaying entries **426 - 450** of **597** in total

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Pathway Name	Protein Name	UniProt ID	Gene Symbol	Organism ▲
RHOU GTPase cycle	ARF GTPase-activating protein Git AT08565p Cdc42 homolog Clathrin heavy chain Discs large 5, isoform A Dynamin associated protein 160, isoform D E3 ubiquitin-protein ligase Su(dx) GTPase-activating protein CdGAPr Growth factor receptor-bound protein 2 Hepatocyte growth factor-regulated tyrosine kinase substrate Jak pathway signal transduction adaptor molecule LD29223p Myosin heavy chain 95F Pi3K21B, isoform B Probable ubiquitin carboxyl-terminal hydrolase FAF Rho-type guanine nucleotide exchange factor, isoform F RhoU, isoform B Serine/threonine-protein kinase PAK mbt Serine/threonine-protein kinase Pak Short stop, isoform H Spectrin alpha chain Spectrin beta chain Vang-like protein non-specific serine/threonine protein kinase receptor protein-tyrosine kinase tRNA (34-2'-O)-methyltransferase regulator WDR6	A0A0B4KEN4 A0A0B4KGS4 A1Z9J3 A8DZ19 M9ND00 O97111 P13395 P29742 P40793 P55824 Q00963 Q01989 Q08012 Q0KHU4 Q7KTZ2 Q86B53 Q95RG8 Q960X8 Q9V4E5 Q9VI13 Q9VIS1 Q9VKG8 Q9VRP3 Q9VXE5 Q9XTL2 Q9Y0H4	38C.40 42/4 5495 ARHGEF7 CG12094 CG12102 CG18637 CG33172 CT3831 CdGAPr Cdc42 Chc D-Pak3 DAP-160 DAP160 DEK DLG5 DPAK DPAK3 DPak3 DPar-6 DPar6 Dap160 Dap160/intersectin Dek Dek7 Deph Dlg Dlg5 Dm-Par-6 Dm-Par6 DmPAK3 DmPAR-6 DmPar-6 DmPar6 Dmel\CG10043 Dmel\CG1099 Dmel\CG14895 Dmel\CG1511 Dmel\CG18076 Dmel\CG2699 Dmel\CG34104 Dmel\CG5495 Dmel\CG5884 Dmel\CG6509 Dmel\CG6521 Dmel\CG8075 Dmpar6 Dp60 Dpak1 Dpak3 DrhoGEF DrtGEF Dstam E(sev)2B Ek7 Eph Git Grb2 Grv Hrs Kak LD32687 Mhc95F P60 PAK-3 PAK3 PAR-6 PAR6 PI(3)K PI3 kinase PI3K PI3K-p60 PI3K-reg PI3K21B PI[[3]]K PaK3 Pak Pak3 Par Par-6 Par6 Pi3K Pi3K21B Pi3Kp60 Pi3k21B Pix RPTK Dek7 Rho/RacGEF RhoGEF RhoU RtGEF SPEC-A STAM Shot Spec-b Stam Stam1 Stb Stbm Su(Mir)1 Su(dx) Txl Txl-RA VANG Vang Vang/Stbm alpha-Spec anon-WO0118547.248 anon-WO0118547.285 arfgap2 beta-PIX beta-Spec betaPIX dP60 dPAK3 dPAR-6 dPI3K dPIX dPar-6 dPix dap160 dek deltap60 dlg5 dmPar-6 dp60 dpak3 dpix drk droPIK57 dstam eph faf grv jar kak kakp kop l(2)CA4 l(2)k03010 l(2)k04204 l(2)k05434 l(2)k05821 l(2)k10821 l(2)k15606 lincRNA.923 mbt noncoding_4110 p160 p60 p85 pak3 par par-6 par6 pix rhoGEF rtGEF shortstop/kakapo shot stam stb stbm stbm/vang strabismus/Van Gogh txl vang vang/stbm vangogh/strabismus	Drosophila melanogaster (fruit fly)
Linoleic acid (LA) metabolism	ATP-binding cassette sub-family D member 1 Elongation of very long chain fatty acids protein Elongation of very long chain fatty acids protein Elongation of very long chain fatty acids protein Very long chain fatty acid elongase 6	A0A0B4KF65 A8JNR0 Q5JZZ4 Q7JUN3 Q9VV87	ABCD Abcd1 Baldspot BcDNA:GH22993 BcDNA:LD10305 CG6261 CG9798 Dmel\CG11801 Dmel\CG31522 Dmel\CG32072 Elo68alpha Elo68beta anon-WO0118547.381 elo68alpha elo68beta l(3)01895 l(3)02281 l(3)04106 l(3)neo21 l(3)neo22 noa	Drosophila melanogaster (fruit fly)
ABC-family proteins mediated transport	26S proteasome non-ATPase regulatory subunit 11 26S proteasome non-ATPase regulatory subunit 13 26S proteasome non-ATPase regulatory subunit 14 26S proteasome non-ATPase regulatory subunit 1 26S proteasome non-ATPase regulatory subunit 2 26S proteasome non-ATPase regulatory subunit 4 26S proteasome non-ATPase regulatory subunit 5 26S proteasome non-ATPase regulatory subunit 6 26S proteasome non-ATPase regulatory subunit 7 26S proteasome non-ATPase regulatory subunit 8 26S proteasome non-ATPase regulatory subunit 9 26S proteasome regulatory complex subunit p48A 26S proteasome regulatory complex subunit p50 26S proteasome regulatory subunit 4 26S proteasome regulatory subunit 7 26S proteasome regulatory subunit 8 ABC transporter domain-containing protein ATP-binding cassette sub-family C member Sur Derlin-1 Derlin Endoplasmic reticulum lectin 1 Eukaryotic translation initiation factor 2 subunit 1 Eukaryotic translation initiation factor 2 subunit 2 Eukaryotic translation initiation factor 2 subunit 3 FI20146p1 FI20190p1 GH11341p GH17761p HMG-coA reductase degradation 3, isoform A Inwardly rectifying potassium channel 1, isoform F Inwardly rectifying potassium channel 2, isoform D Inwardly rectifying potassium channel 3, isoform D LD04461p LD17001p LD28489p LD42916p LD45860p Multidrug resistance protein 4 Multidrug-Resistance like protein 1, isoform I Polyubiquitin Probable 26S proteasome non-ATPase regulatory subunit 3 Probable multidrug resistance-associated protein lethal(2)03659 Proteasome inhibitor PI31 subunit Proteasome subunit alpha type-1 Proteasome subunit alpha type-2 Proteasome subunit alpha type-3 Proteasome subunit alpha type-4 Proteasome subunit alpha type-5 Proteasome subunit alpha type-6 Proteasome subunit alpha type-7-1 Proteasome subunit alpha type-7-1A Proteasome subunit alpha type-7-1B Proteasome subunit beta type-3 Proteasome subunit beta type-4 Proteasome subunit beta Proteasome subunit beta Proteasome subunit beta Proteasome subunit beta Proteasome subunit beta Proteasome subunit beta Proteasome subunit beta RING-type E3 ubiquitin transferase RING-type E3 ubiquitin transferase RING-type E3 ubiquitin transferase RING-type E3 ubiquitin transferase RING-type E3 ubiquitin transferase Regulatory particle triple-A ATPase 4 Transitional endoplasmic reticulum ATPase TER94 Ubiquitin-like domain-containing protein Ubiquitin-ribosomal protein eS31 fusion protein Uncharacterized protein, isoform B Uncharacterized protein, isoform E Uncharacterized protein, isoform E Uncharacterized protein Uncharacterized protein Uncharacterized protein proteasome endopeptidase complex	A0A0B4KGI0 A0A0B4KH86 A0A0B4LHI9 A0A1Z1CK50 A0AQH0 B7YZX2 O18413 P0CG69 P12881 P15357 P18053 P22769 P25161 P26270 P40301 P41374 P41375 P48601 P55035 P91660 Q24178 Q24208 Q27575 Q7K148 Q7KLV9 Q7KMP8 Q7KMQ0 Q7KN62 Q7KT22 Q7KTC0 Q86B52 Q8INY4 Q8IQM1 Q8IR26 Q8MT77 Q8T915 Q95083 Q961D3 Q9V3G7 Q9V3H2 Q9V3P3 Q9V3P6 Q9V3V6 Q9V3Z4 Q9V405 Q9V415 Q9V436 Q9V5C6 Q9V637 Q9VAN4 Q9VC63 Q9VEU2 Q9VFS8 Q9VFY3 Q9VGM1 Q9VJ21 Q9VJJ0 Q9VKC7 Q9VL32 Q9VLN6 Q9VLP5 Q9VNA5 Q9VQ57 Q9VUJ1 Q9VW54 Q9VXP1 Q9VYG1 Q9VYW4 Q9W1S5 Q9W2I5 Q9W414 Q9W418 Q9W470 Q9XYN7 Q9XZJ4 R9PY16 X2JG15	0718/06 1(2)05070 1341 16916 17331 31742 3329 718/06 8392 ABCC1 BEST:CK01227 BEST:CK02472 B[[1]] B[[2]] BcDNA.GH12068 BcDNA:AT04622 BcDNA:AT26376 BcDNA:GH12068 BcDNA:LD21723 BcDNA:LD23587 Beta 2 subunit Beta-1 Beta-2 Beta-4 Beta-5 CG10180 CG10441 CG12096 CG13836 CG17338 CG1819 CG18282 CG32516 CG32581-RA CG32847-RB CG33173 CG5789-RA CG6747 CG6766-RA CG7627-RA CG8473 CG9588 CK01227 CR11700 CR32744 CT14766 CT28749 Cftr Cg14899 DER1 DIR DTS-7 DTS57 DTS7 DUG Der-1 Der-2 Dir DmCG31792 DmCG31793 DmCG6214 DmCG7627 DmCG7806 DmCG9270 DmREGgamma DmTBP-1 DmUb DmUbi-p5E Dm_3R:100326 Dm_3R:100349 Dm_Rpt1 Dm_Rpt3a Dm_Rpt4a Dm_Rpt4b Dm_Rpt5a Dm_Rpt5b Dme_CG10505 Dme_CG11898 Dme_CG14709 Dme_CG4562 Dme_CG5789 Dme_CG7627 Dme_CG7806 Dme_CG9270 Dmel\CG10221 Dmel\CG10230 Dmel\CG10369 Dmel\CG10370 Dmel\CG10505 Dmel\CG1100 Dmel\CG11700 Dmel\CG11897 Dmel\CG11898 Dmel\CG12161 Dmel\CG12323 Dmel\CG1341 Dmel\CG14709 Dmel\CG14899 Dmel\CG1591 Dmel\CG16916 Dmel\CG1703 Dmel\CG17331 Dmel\CG18341 Dmel\CG31742 Dmel\CG31792 Dmel\CG31793 Dmel\CG32581 Dmel\CG32744 Dmel\CG32847 Dmel\CG3329 Dmel\CG34120 Dmel\CG34308 Dmel\CG3455 Dmel\CG4157 Dmel\CG43672 Dmel\CG4370 Dmel\CG44159 Dmel\CG4562 Dmel\CG5789 Dmel\CG6214 Dmel\CG6766 Dmel\CG7627 Dmel\CG7762 Dmel\CG7806 Dmel\CG8141 Dmel\CG8392 Dmel\CG8974 Dmel\CG9270 Dmel\CG9868 Dmp42D Dmp48A Dmp48B Dox-A2 Dts7 EP3221 ESTS:143G11T ESTS:199A6T GC17331 HRD3 Hrd3 Ir Irk1 Irk2 Irk3 Kir1 Kir2 LD08717 MRP MRP1 Mov34 Mrp Mrp1 Mrp4 Mrp5 P26s4 PI31 PROS-25 PROS-28.1 PROS-29 PROS-35 PROS-54 PROSbeta2 PSMB2 PSMB5 PSMD13 Pros b5 Pros beta4 Pros-beta-2 Pros-beta-5 Pros-beta-5R1 Pros25 Pros26.4 Pros26S Pros26S-RS6A Pros28.1 Pros28.1A Pros28.1B Pros29 Pros35 Pros45 Pros54 ProsMA5 Prosalpha1 Prosalpha2 Prosalpha3 Prosalpha4 Prosalpha4T1 Prosalpha4T2 Prosalpha5 Prosalpha6 Prosalpha7 Prosb4 Prosbeta Prosbeta 2 Prosbeta1 Prosbeta2 Prosbeta2R1 Prosbeta2R2 Prosbeta3 Prosbeta4 Prosbeta5 Prosbeta5R Prosbeta5R1 Prosbeta5R1-RA Prosbeta5R2 Prosbeta7 Psmb2 Q7KMQ0_DROME REG REGgamma RPN1 RPN5 RPT5 RpS27A Rpn1 Rpn10 Rpn11 Rpn12 Rpn2 Rpn3 Rpn4 Rpn5 Rpn6 Rpn7 Rpn8 Rpn9 Rpn94 Rpt1 Rpt2 Rpt3 Rpt3-RA Rpt4 Rpt5 Rpt6 S10b S11 S14 S2 S6 S6' S6B S7 Sur TBP-1 TBP7 TER94 Tbp-1 Tbp1 UB UB3-D UBI-F80 Ub Ubi Ubi-m Ubi-p5E Ubi-p5E5 Ubi-p63E Ubiq Ubiquitin Ug VCP anon-AE003657.1 anon-EST:fe1E6 anon-EST:fe1G6 anon-WO0118547.116 anon-WO0118547.90 anon-WO0153538.10 anon-WO0153538.8 anon-WO0153538.9 anon-sts41 b2 beta 2 beta-1 beta-2 beta-4 beta-5 beta1 beta2 beta2R1 beta2R2 beta2_dm beta4 beta5 beta5R1 beta5R2 cg6766 dDer-2 dIRK dIRK-2 dIRK-3 dKir dKirI dKirII dKirIII dMRP dMRP/CG6214 dMRP1 dMRP4 dREG dREGgamma dReg dReggamma dRpn12 dRpt1 dRpt5 dbeta5 dmrp eIF-2beta eIF-2gamma eIF2-alpha eIF2a eIF2alpha eIF2beta eIF2g eIF2gamma ir irk1 irk2 irk3 l(1)G0052 l(1)G0114 l(1)G0227 l(1)G0345 l(2)03659 l(2)05070 l(2)05070-RA l(2)05643 l(2)43Ed l(3)04210 l(3)DTS7 l(3)S071806 l(3)S071806b ldd lincRNA.123 p30 p39A p42D p48A p48B p50 p55 p97 poly-ub prosbeta prosbeta1 prosbeta2 rdog rpn1 rpn12 rpn5 rpn9 rpt3 sordd1 sordd2 tbp-1 yip5	Drosophila melanogaster (fruit fly)
LDL clearance	AP complex subunit beta AP complex subunit sigma AP-2 complex subunit alpha Adaptor protein complex 2, mu subunit, isoform A Clathrin heavy chain Clathrin light chain Esterase-6 LD11117p Lipophorin receptor 1, isoform K NPC intracellular cholesterol transporter 2 homolog a Niemann-Pick type C-1a, isoform A O-acyltransferase	A8JRD0 O62530 P08171 P29742 P91926 Q24253 Q7YU01 Q8MYW9 Q9VDC3 Q9VL24 Q9VQ62 Q9VWA1	ACAT ACAT1 AP-1-2-beta AP-1-2beta AP-1/2beta AP-1beta AP-1beta1 AP-2 sigma AP-2-sigma AP-2alpha AP-2beta AP-2mu AP-2sigma AP-50 AP-beta1 AP1beta1 AP2 AP2-sigma AP2beta2 AP2mu2 AP50 BAD1 BAP Bap Beta-adaptin CG31095 CG4823 CG4834 CG4861 CG4870 CG4874 CT15569 Chc Clc DmNPC Dmel\CG12532 Dmel\CG31092 Dmel\CG31094 Dmel\CG5722 Dmel\CG6056 Dmel\CG7057 Dmel\CG8112 Dmu2 EST6 Est-6 LDLR LpR1 LpR2 Lpr2 Lpr2-E MENE (3R)-D MENE(3R)-D NPC-1 NPC1 NPC1a NPC2 Npc1 Npc1_Dm Npc1a Npc2a anon-EST:Posey50 anon-WO0172774.104 apl1 apl2 apm4 aps2 bap beta1/2 beta2-ada cg12532 cg6056 cg7057 dNPC1 dNPC1a dmNPC1 dncp1a dnpc1a lpr1 lpr2 mu2 mu2-ada npc1 npc1a sigma2 sigma2-ada	Drosophila melanogaster (fruit fly)
Regulation of ornithine decarboxylase (ODC)	26S proteasome non-ATPase regulatory subunit 11 26S proteasome non-ATPase regulatory subunit 13 26S proteasome non-ATPase regulatory subunit 14 26S proteasome non-ATPase regulatory subunit 1 26S proteasome non-ATPase regulatory subunit 2 26S proteasome non-ATPase regulatory subunit 4 26S proteasome non-ATPase regulatory subunit 5 26S proteasome non-ATPase regulatory subunit 6 26S proteasome non-ATPase regulatory subunit 7 26S proteasome non-ATPase regulatory subunit 8 26S proteasome non-ATPase regulatory subunit 9 26S proteasome regulatory complex subunit p48A 26S proteasome regulatory complex subunit p50 26S proteasome regulatory subunit 4 26S proteasome regulatory subunit 7 26S proteasome regulatory subunit 8 GH11341p LD45860p Ornithine decarboxylase 1 Ornithine decarboxylase 2 Ornithine decarboxylase antizyme Probable 26S proteasome non-ATPase regulatory subunit 3 Proteasome inhibitor PI31 subunit Proteasome subunit alpha type-1 Proteasome subunit alpha type-2 Proteasome subunit alpha type-3 Proteasome subunit alpha type-4 Proteasome subunit alpha type-5 Proteasome subunit alpha type-6 Proteasome subunit alpha type-7-1 Proteasome subunit alpha type-7-1A Proteasome subunit alpha type-7-1B Proteasome subunit beta type-3 Proteasome subunit beta type-4 Proteasome subunit beta Proteasome subunit beta Proteasome subunit beta Proteasome subunit beta Proteasome subunit beta Proteasome subunit beta Proteasome subunit beta Regulatory particle triple-A ATPase 4 proteasome endopeptidase complex	A0AQH0 O18413 P12881 P18053 P22769 P25161 P26270 P40301 P40807 P40808 P48601 P54361 P55035 Q24178 Q27575 Q7K148 Q7KLV9 Q7KMP8 Q7KMQ0 Q8INY4 Q8T915 Q95083 Q9V3G7 Q9V3H2 Q9V3P3 Q9V3P6 Q9V3V6 Q9V3Z4 Q9V405 Q9V436 Q9V5C6 Q9V637 Q9VFS8 Q9VJJ0 Q9VNA5 Q9VUJ1 Q9VW54 Q9VYG1 Q9W1S5 Q9W414 Q9W470 Q9XYN7 Q9XZJ4	0718/06 1(2)05070 1341 16916 17331 31742 3329 718/06 8392 B[[1]] B[[2]] BcDNA.GH12068 BcDNA:GH12068 BcDNA:LD21723 Beta 2 subunit Beta-1 Beta-2 Beta-4 Beta-5 CG12096 CG9588 CT28749 DTS-7 DTS57 DTS7 DUG DmREGgamma DmTBP-1 Dm_Rpt1 Dm_Rpt3a Dm_Rpt4a Dm_Rpt4b Dm_Rpt5a Dm_Rpt5b Dmel\CG10230 Dmel\CG10370 Dmel\CG1100 Dmel\CG12161 Dmel\CG12323 Dmel\CG1341 Dmel\CG1591 Dmel\CG16916 Dmel\CG17331 Dmel\CG18341 Dmel\CG31742 Dmel\CG3329 Dmel\CG3455 Dmel\CG4157 Dmel\CG7762 Dmel\CG8392 Dmel\CG9868 Dmp42D Dmp48A Dmp48B Dox-A2 Dts7 GC17331 LD08717 Mov34 Oda Odc1 Odc2 P26s4 PI31 PROS-25 PROS-28.1 PROS-29 PROS-35 PROS-54 PROSbeta2 PSMB2 PSMB5 PSMD13 Pros b5 Pros beta4 Pros-beta-2 Pros-beta-5 Pros-beta-5R1 Pros25 Pros26.4 Pros26S Pros26S-RS6A Pros28.1 Pros28.1A Pros28.1B Pros29 Pros35 Pros45 Pros54 ProsMA5 Prosalpha1 Prosalpha2 Prosalpha3 Prosalpha4 Prosalpha4T1 Prosalpha4T2 Prosalpha5 Prosalpha6 Prosalpha7 Prosb4 Prosbeta Prosbeta 2 Prosbeta1 Prosbeta2 Prosbeta2R1 Prosbeta2R2 Prosbeta3 Prosbeta4 Prosbeta5 Prosbeta5R Prosbeta5R1 Prosbeta5R1-RA Prosbeta5R2 Prosbeta7 Psmb2 Q7KMQ0_DROME REG REGgamma RPN1 RPN5 RPT5 Rpn1 Rpn10 Rpn11 Rpn12 Rpn2 Rpn3 Rpn4 Rpn5 Rpn6 Rpn7 Rpn8 Rpn9 Rpn94 Rpt1 Rpt2 Rpt3 Rpt3-RA Rpt4 Rpt5 Rpt6 S10b S11 S14 S2 S6 S6' S6B S7 TBP-1 TBP7 Tbp-1 Tbp1 Ug anon-AE003657.1 anon-EST:fe1E6 anon-EST:fe1G6 anon-WO0118547.116 anon-WO0118547.90 anon-WO0153538.10 anon-WO0153538.8 anon-WO0153538.9 b2 beta 2 beta-1 beta-2 beta-4 beta-5 beta1 beta2 beta2R1 beta2R2 beta2_dm beta4 beta5 beta5R1 beta5R2 dREG dREGgamma dReg dReggamma dRpn12 dRpt1 dRpt5 dbeta5 guf l(1)G0052 l(1)G0114 l(1)G0227 l(1)G0345 l(2)05070 l(2)05070-RA l(2)05643 l(2)43Ed l(3)04210 l(3)DTS7 l(3)S071806 l(3)S071806b p30 p39A p42D p48A p48B p50 p55 p97 prosbeta prosbeta1 prosbeta2 rpn1 rpn12 rpn5 rpn9 rpt3 tbp-1 yip5	Drosophila melanogaster (fruit fly)
Synthesis of active ubiquitin: roles of E1 and E2 enzymes	E1 ubiquitin-activating enzyme E2 ubiquitin-conjugating enzyme E2 ubiquitin-conjugating enzyme E2 ubiquitin-conjugating enzyme FI11905p GH17761p LD28546p N-terminal E2 ubiquitin-conjugating enzyme Polyubiquitin Probable ubiquitin carboxyl-terminal hydrolase FAF Ubiquitin carboxyl-terminal hydrolase 7 Ubiquitin carboxyl-terminal hydrolase Ubiquitin carboxyl-terminal hydrolase Ubiquitin-conjugating enzyme E2 C Ubiquitin-conjugating enzyme E2 S Ubiquitin-conjugating enzyme E2 S Ubiquitin-conjugating enzyme E2-17 kDa Ubiquitin-conjugating enzyme E2-17 kDa Ubiquitin-conjugating enzyme E2-18 kDa Ubiquitin-conjugating enzyme E2-22 kDa Ubiquitin-conjugating enzyme E2-24 kDa Ubiquitin-like domain-containing protein Ubiquitin-ribosomal protein eS31 fusion protein	A1Z8B5 P0CG69 P15357 P25153 P25867 P35122 P52485 P52486 P55824 Q29R09 Q7JW03 Q7K738 Q8SYG3 Q8T0L3 Q9VTY6 Q9VUR4 Q9VX25 Q9VXE8 Q9VYN3 Q9VYQ8 Q9VZU7 Q9W418 R9PY16	2/31 BEST:GH28095 BcDNA:GH28095 BcDNA:RE63412 CG1208 CG18282 CG7220-RB CG7656-RA CG8188 CR11700 CR32744 Crl Dhr6 DmUSP5 DmUb DmUba1 DmUbi-p5E DmUsp5 Dmel\CG11700 Dmel\CG12082 Dmel\CG1782 Dmel\CG2257 Dmel\CG2574 Dmel\CG2924 Dmel\CG32744 Dmel\CG40045 Dmel\CG4443 Dmel\CG7220 Dmel\CG7656 E1 EG:25E8.2 ESTS:143G11T ESTS:199A6T FBtr0088499 NICE5 Q9VZU7 RpS27A UB UB3-D UBA-1 UBA1 UBC7 UBI-F80 USP5 Ub Uba Uba 1 Uba1 Ubc-2EH Ubc-E2H Ubc-E2Hs Ubc10 Ubc2 Ubc4 Ubc47D Ubc6 Ubc7 UbcD1 UbcD2 UbcD4 UbcD6 UbcD7 UbcDE2H UbcE2H Ubch10 Ube2G1 Ube2W Ubi Ubi-m Ubi-p5E Ubi-p5E5 Ubi-p63E Ubiq Ubiquitin Uch Usp5 Usp7 anon-sts41 bs21b01.y1 col crl dUbc-E2H eff faf l(2)03405 l(2)05642 l(2)s3484 leon poly-ub uba-1 uba1 ubc-D ubcD10 ubcE2h usp5 vih	Drosophila melanogaster (fruit fly)
betaKlotho-mediated ligand binding	Fibroblast growth factor receptor homolog 1 Fibroblast growth factor receptor homolog 2 Fibroblast growth factor LP05116p	Q07407 Q09147 Q9VDT9 Q9VV98	BNL Bnl Branchless DFGF DmBnl Dmel\CG4608 Dmel\CG9701 FGF FR1 FR2 HD-311 Tk1 Tk2 bnl btl dFGF htl klotho l(3)06916 l(3)neo52	Drosophila melanogaster (fruit fly)
EPH-Ephrin signaling	Ephrin receptor protein-tyrosine kinase	Q9V4E1 Q9V4E5	CT3831 DEK Dek Dek7 Deph Dmel\CG1511 Dmel\CG1862 Ek7 Eph Ephrin RPTK Dek7 dek eph ephrin lincRNA.922 lincRNA.923	Drosophila melanogaster (fruit fly)
Presynaptic depolarization and calcium channel opening	Ca2+-channel-protein-beta-subunit, isoform L Ca[2+] channel Muscle-specific alpha2/delta subunit, isoform A GH12419p1 Stolid, isoform H Straightjacket, isoform C Voltage-dependent calcium channel type A subunit alpha-1	A0A0B4K866 M9PD84 P91645 Q8IP22 Q9VRE6 X2J9Z3	2L5 BG:DS07108.2 BG:DS07473.1 CG10985 CG11568 CG11569 CG12455 CG14922 CG14923 CG32514 CG32514-ORFA CG33305 CG6320 Ca-Ma2d Ca-beta CaBeta DS07108.2 DS07473.1A DmCa1beta Dmel\CG12295 Dmel\CG33670 Dmel\CG42403 Dmel\CG42817 Dmel\CG4587 Dro STG1 Ma2/d STG1 Stg1 alpha2delta-3 alpha[[2]]delta alpha[[2]]delta-3 ca-beta cac dalpha[[2]]delta-3 dmcab1 l(2)04008 l(2)k10814 mdcds_3066 nbA nonB stg1 stg1-RA stj stol	Drosophila melanogaster (fruit fly)
mRNA Capping	CDK-activating kinase assembly factor MAT1 Cyclin-H Cyclin-dependent kinase 7 DNA-directed RNA polymerase II subunit RPB11 DNA-directed RNA polymerase II subunit RPB1 DNA-directed RNA polymerase II subunit RPB2 DNA-directed RNA polymerase II subunit RPB7 DNA-directed RNA polymerase II subunit RPB9 DNA-directed RNA polymerase II subunit Rpb4 DNA-directed RNA polymerases I, II, and III subunit RPABC2 DNA-directed RNA polymerases I, II, and III subunit RPABC3 DNA-directed RNA polymerases I, II, and III subunit RPABC5 GEO11084p1 GH07456p General transcription and DNA repair factor IIH helicase subunit XPD General transcription and DNA repair factor IIH helicase/translocase subunit XPB General transcription and DNA repair factor IIH subunit TFB5 General transcription factor IIF subunit 1 General transcription factor IIF subunit 2 General transcription factor IIH subunit 1 General transcription factor IIH subunit 3 General transcription factor IIH subunit 4 General transcription factor IIH subunit Nuclear cap-binding protein subunit 1 Nuclear cap-binding protein subunit 2 RPB5 homolog Transcription elongation factor SPT5 mRNA cap guanine-N7 methyltransferase mRNA-capping enzyme	B7Z018 O76513 O97183 P04052 P08266 P36958 P41900 Q02870 Q05913 Q24216 Q24320 Q6IGE3 Q7JZF5 Q7K4N3 Q7KPG8 Q7KVP9 Q960E8 Q9V3L6 Q9V460 Q9VC49 Q9VEA5 Q9VFB5 Q9VJE4 Q9VJQ4 Q9VNP8 Q9VNZ3 Q9VPX4 Q9VUR1 Q9VY44	142767_at 152117_at 154538_at AT-1 BG:DS00941.10 CCNH CD 7 CDK7 CG14037 CG6572 Cbp20 Cbp80 Cdk7 CycH D-rpII33 DhR3 DhXPD DmCDK7 DmCdk7 DmMO15 DmMo15 DmRPB5 DmXPD Dmcdk7 Dmel\CG11115 Dmel\CG11246 Dmel\CG11979 Dmel\CG1810 Dmel\CG31155 Dmel\CG3319 Dmel\CG34186 Dmel\CG42373 Dmel\CG5041 Dmel\CG7405 Dmel\CG7614 Dmel\CG7764 Dmel\CG7885 Dmel\CG9433 Dmp34 Dmp52 Dmp8 ERCC2 ERCC3 MAT1 Mat1 Mo15 PIR Pol II Pol II RPII33 PolII PolIIo Polr2A Polr2B Polr2C Polr2D Polr2E Polr2F Polr2G Polr2H Polr2I Polr2J Polr2K Polr2L RNA Pol II RNA pol II RNA polII RNAP RP140 RPB1 RPB12 RPB2 RPB3 RPB5 RPB6 RPB7 RPB8 Rbp3 Rnmt RpABC14 RpII140 RpII15 RpII18 RpII215 RpII33 Rpb10 Rpb11 Rpb12 Rpb3 Rpb4 Rpb5 Rpb7 Rpb8 Rpll33 SSL1 Spt5 Ssl1 TFB2 TFB4 TFB5 TFB5 (uORF) TFIIF30 TTDA TfIIFalpha TfIIFbeta Tfb1 Tfb2 Tfb4 Tfb5 Tfb5-RB XPD XPD/ERCC2 Xpd anon-WO0118547.648 br17 br9 cdk-7 cdk7 dCdk7 dRpb7 hay l(2)34Dg l(2)SH1279 l(2)SH2 1279 l(2)SH2 2137 l(2)SH2137 l(2)br17 l(2)br9 l(2)k05605 l(3)E35 l34Dg lincRNA.843 mRNA-cap mRNA-capping-enzyme mrn ms(3)nc16 nc16 p34 p40[MO15] p44 p52 p8 pol II polII rpII33 rpb3 ssl1 uORF xpd	Drosophila melanogaster (fruit fly)
Nuclear signaling by ERBB4	Epidermal growth factor receptor Estrogen-related receptor splice variant Gamma-secretase subunit Aph-1 Gamma-secretase subunit pen-2 Knirps-related protein Nicastrin Presenilin homolog Protein embryonic gonad Signal transducer and transcription activator Tyrosine-protein kinase Src64B WW domain-containing oxidoreductase Zygotic gap protein knirps	O02194 P00528 P04412 P10734 P13054 P15370 Q24151 Q86BE9 Q8WS79 Q9VC27 Q9VLU5 Q9VQG2	DER Derr Dmel\CG7404 ERR Egfr MARE NCSTN NR0A1 NR0A2 NR0A3 NR3B4 Nct PS PSF Psn Src1 Src64B Stat Stat92E Wwox aph-1 c-erbB dERR eg egon kni knrl mrL pen-2 spry top	Drosophila melanogaster (fruit fly)
Nuclear Pore Complex (NPC) Disassembly	Aladin Cyclin-dependent kinase 1 E3 SUMO-protein ligase RanBP2 G2/mitotic-specific cyclin-B Nuclear pore complex protein Nup107 Nuclear pore complex protein Nup133 Nuclear pore complex protein Nup153 Nuclear pore complex protein Nup154 Nuclear pore complex protein Nup160 homolog Nuclear pore complex protein Nup205 Nuclear pore complex protein Nup214 Nuclear pore complex protein Nup50 Nuclear pore complex protein Nup58 Nuclear pore complex protein Nup75 Nuclear pore complex protein Nup88 Nuclear pore complex protein Nup98-Nup96 Nuclear pore glycoprotein p62 Nuclear pore membrane glycoprotein 210 Nuclear pore protein Nucleoporin 43kD Nucleoporin NUP42 Nucleoporin Ndc1 Nucleoporin Nup188 Nucleoporin Nup35 Nucleoporin Nup37 Nucleoporin seh1 Nucleoprotein TPR Probable nucleoporin Nup54 Protein Rae1 Protein SEC13 homolog	A0A0B4K7J2 A0A0B4K859 A1YK02 A1Z6H7 A1Z8P9 P20439 P23572 Q7JXF5 Q7K0D8 Q7K2X8 Q8IQV9 Q9GYU8 Q9I7N2 Q9V3J4 Q9V463 Q9V466 Q9V6B9 Q9VBU8 Q9VCG4 Q9VCH5 Q9VCW3 Q9VDV3 Q9VE85 Q9VFE7 Q9VKJ3 Q9VWS2 Q9VXE6 Q9W1X4 Q9W2E7 Q9W351	Aladin Bx34 Cdk1 Cg7262 CycB Dmel\CG18787 Dmel\CG7262 Dmel\CG7671 Gp188 Gp210 Mtor Ndc1 Nup107 Nup133 Nup145 Nup153 Nup154 Nup155 Nup160 Nup188 Nup205 Nup214 Nup35 Nup358 Nup37 Nup43 Nup44A Nup50 Nup53 Nup54 Nup58 Nup62 Nup75 Nup88 Nup93 Nup93-2 Nup98 Nup98-96 Rae1 RanBP2 Sec13 cdc2 l(2)k03905 lyadi mbo nup43 nup93 seh1	Drosophila melanogaster (fruit fly)
IRS-mediated signalling	Insulin receptor substrate 1 PI-3 kinase Pi3K21B, isoform B	P91634 Q7KTZ2 Q9XTN2	DP110 Dmel\CG2699 Dmel\CG4141 Dmp110 Dp110 Dp110/PI3K Dp60 Dpp110 IRS P60 PI(3)K PI-3 kinase PI-3-K PI3 kinase PI3'K PI3K PI3K-92D PI3K-92E/Dp110 PI3K-Dp110 PI3K-I PI3K-dp110 PI3K-p60 PI3K-reg PI3K21B PI3K92E PI3k PI[[3]]K Pi3K Pi3K21B Pi3K92D Pi3K92E Pi3K92E p110 Pi3Kp110 Pi3Kp60 Pi3k Pi3k21B Pi3k92e PiK92E anon-92Ed chico dP110 dP13K dP60 dPI3K dPI3K[92E] deltap60 dp110 dp110alpha dp60 dpP110 droPIK57 p110 p120 p60 p85 pi3k pi3k92E pi3k92e rea type-1 PI3K	Drosophila melanogaster (fruit fly)
Downregulation of TGF-beta receptor signaling	E3 ubiquitin-protein ligase CHIP E3 ubiquitin-protein ligase Smurf1 GH17761p Maverick Mothers against decapentaplegic homolog Mothers against decapentaplegic homolog Phosphatidylinositol-3-phosphate phosphatase Polyubiquitin Protein decapentaplegic Serine-threonine kinase receptor-associated protein Serine/threonine-protein kinase receptor Ubiquitin-like domain-containing protein Ubiquitin-ribosomal protein eS31 fusion protein receptor protein serine/threonine kinase	A0A0B4KG59 A0A6H2EEY2 A1Z7L8 O96660 P07713 P0CG69 P15357 Q7YU03 Q9V4E6 Q9V853 Q9W1N4 Q9W418 Q9XYW6 R9PY16	1883 ATR-1 ATR-I Act-r Atf1 Atr Atr-1 Atr-I Atr-II Atr45A Atr88CD AtrI AtrII BABO Bab Babo Babo-a BaboA CG18282 CG3957/wmd CHIP CR11700 CR32744 Chip DAD DSMAD2 DSmad2 Dad DmUb DmUbi-p5E Dmel\CG11700 Dmel\CG1901 Dmel\CG2262 Dmel\CG32744 Dmel\CG3632 Dmel\CG3957 Dmel\CG5201 Dmel\CG5203 Dmel\CG7904 Dmel\CG8224 EP(3)3196 EP3196 ESTS:143G11T ESTS:199A6T Gprk-3 Gprk3 MAV Mav PUNT Punt Put RpS27A SMAD2 SMOX STK-C STK-E STUB1 Sad Smad Smad2 SmoX Smox Smurf Smurf1 Stub1 TGF-B TGF-b TGF-beta Tgf-r UB UB3-D UBI-F80 Ub Ubi Ubi-m Ubi-p5E Ubi-p5E5 Ubi-p63E Ubiq Ubiquitin Unrip WMD anon-EST:fe1F5 anon-sts41 atr-I atrII babo dCHIP dSMAD2 dSmad2 dad dlhC dpp dsmad2 l(1)G0348 l(2)44Fd l(2)k16912 l(3)10460 l(3)j1E4 l(3)j5A5 lack mav poly-ub pter pun put sad smad2 smox ted tmp wmd	Drosophila melanogaster (fruit fly)
Intrinsic Pathway of Fibrin Clot Formation	Accessory gland protein Acp76A CG6687 protein FI01422p GH10112p GH18514p IP10416p MIP05602p Male accessory gland protein RE02548p RE27547p SD11922p Serine protease inhibitor 27A Serine protease inhibitor 42Dd Serine protease inhibitor 88Ea Serpin 100A Serpin 28B, isoform A Serpin 28Da Serpin 28Db Serpin 28F Serpin 38F, isoform A Serpin 42Db, isoform C Serpin 42Dc, isoform A Serpin 43Aa Serpin 4 Serpin 85F Serpin domain-containing protein	A1Z6I3 A1Z6R3 A1Z6R4 A1Z6V5 Q0E8V6 Q3HKQ3 Q4V3G2 Q7JV69 Q7JWX3 Q7K508 Q7K8Y5 Q7KA66 Q7YTY6 Q8SYY7 Q8SZF4 Q9V3N1 Q9VA48 Q9VFC1 Q9VFC2 Q9VH46 Q9VII7 Q9VL44 Q9VLQ7 Q9VLV3 Q9VLZ8 Q9VVW1	6h1 Acp76A BG642378 BG642378(6h1) CG12318 CG12551 CG14470 CG4804-RA Dmel\CG10913 Dmel\CG10956 Dmel\CG12172 Dmel\CG12807 Dmel\CG1342 Dmel\CG1857 Dmel\CG1859 Dmel\CG1865 Dmel\CG31902 Dmel\CG32203 Dmel\CG33121 Dmel\CG43366 Dmel\CG4804 Dmel\CG6687 Dmel\CG6717 Dmel\CG7722 Dmel\CG8137 Dmel\CG9334 Dmel\CG9453 Dmel\CG9454 Dmel\CG9455 Dmel\CG9460 NEC Nec SER1 SER2 SER3 Ser1 Ser2 Ser3 Serp2 Sp2 Sp3 Sp4 Sp6 Spn1 Spn100 Spn100A Spn2 Spn27A Spn28B Spn28Da Spn28Db Spn28F Spn3 Spn31A Spn38F Spn4 Spn42Da Spn42Db Spn42Dc Spn42Dd Spn42De Spn43 Aa Spn43A Spn43Aa Spn43Ab Spn43Ac Spn43Ad Spn47C Spn4A Spn5 Spn53F Spn55B Spn6 Spn7 Spn75F Spn85F Spn88Ea Spn88Eb anon-WO0118057.1 anon-WO0118057.2 anon-WO0118057.3 dSerp2 nec sp-6 sp2 sp3 sp4 sp6 spn2 spn4 spn43Ab spn47C	Drosophila melanogaster (fruit fly)
Peptidoglycan bound PGRP-LC/LE oligomerises	Peptidoglycan-recognition protein LE	Q9VXN9	PGRP-LE	Drosophila melanogaster (fruit fly)
FCERI mediated NF-kB activation	26S proteasome non-ATPase regulatory subunit 11 26S proteasome non-ATPase regulatory subunit 13 26S proteasome non-ATPase regulatory subunit 14 26S proteasome non-ATPase regulatory subunit 1 26S proteasome non-ATPase regulatory subunit 2 26S proteasome non-ATPase regulatory subunit 4 26S proteasome non-ATPase regulatory subunit 5 26S proteasome non-ATPase regulatory subunit 6 26S proteasome non-ATPase regulatory subunit 7 26S proteasome non-ATPase regulatory subunit 8 26S proteasome non-ATPase regulatory subunit 9 26S proteasome regulatory complex subunit p48A 26S proteasome regulatory complex subunit p50 26S proteasome regulatory subunit 4 26S proteasome regulatory subunit 7 26S proteasome regulatory subunit 8 Dorsal-related immunity factor Dif Embryonic polarity protein dorsal GH11341p Inhibitor of nuclear factor kappa-B kinase subunit beta LD45860p NF-kappa-B essential modulator NF-kappa-B inhibitor cactus Nuclear factor NF-kappa-B p110 subunit Probable 26S proteasome non-ATPase regulatory subunit 3 Proteasome inhibitor PI31 subunit Proteasome subunit alpha type-1 Proteasome subunit alpha type-2 Proteasome subunit alpha type-3 Proteasome subunit alpha type-4 Proteasome subunit alpha type-5 Proteasome subunit alpha type-6 Proteasome subunit alpha type-7-1 Proteasome subunit alpha type-7-1A Proteasome subunit alpha type-7-1B Proteasome subunit beta type-3 Proteasome subunit beta type-4 Proteasome subunit beta Proteasome subunit beta Proteasome subunit beta Proteasome subunit beta Proteasome subunit beta Proteasome subunit beta Proteasome subunit beta Putative protein kinase C delta type homolog Regulatory particle triple-A ATPase 4 proteasome endopeptidase complex	A0AQH0 O18413 P12881 P15330 P18053 P22769 P25161 P26270 P40301 P48601 P55035 P83099 P98149 Q03017 Q24178 Q27575 Q7K148 Q7KLV9 Q7KMP8 Q7KMQ0 Q8INY4 Q8T915 Q94527 Q95083 Q9GYV5 Q9V3G7 Q9V3H2 Q9V3P3 Q9V3P6 Q9V3V6 Q9V3Z4 Q9V405 Q9V436 Q9V5C6 Q9V637 Q9VEZ5 Q9VFS8 Q9VJJ0 Q9VNA5 Q9VUJ1 Q9VW54 Q9VYG1 Q9W1S5 Q9W414 Q9W470 Q9XYN7 Q9XZJ4	0718/06 1(2)05070 1341 16916 17331 31742 3329 718/06 8392 B[[1]] B[[2]] BcDNA.GH12068 BcDNA:GH12068 BcDNA:LD21723 Beta 2 subunit Beta-1 Beta-2 Beta-4 Beta-5 CG12096 CG9588 CT28749 DIK DTS-7 DTS57 DTS7 DUG Dif DmREGgamma DmTBP-1 Dm_Rpt1 Dm_Rpt3a Dm_Rpt4a Dm_Rpt4b Dm_Rpt5a Dm_Rpt5b Dmel\CG10230 Dmel\CG10370 Dmel\CG1100 Dmel\CG12161 Dmel\CG12323 Dmel\CG1341 Dmel\CG1591 Dmel\CG16916 Dmel\CG17331 Dmel\CG18341 Dmel\CG31742 Dmel\CG3329 Dmel\CG3455 Dmel\CG4157 Dmel\CG7762 Dmel\CG8392 Dmel\CG9868 Dmp42D Dmp48A Dmp48B Dox-A2 Dts7 GC17331 IKKGAMMA IKKbeta LD08717 Mov34 P26s4 PI31 PROS-25 PROS-28.1 PROS-29 PROS-35 PROS-54 PROSbeta2 PSMB2 PSMB5 PSMD13 Pkcdelta Pros b5 Pros beta4 Pros-beta-2 Pros-beta-5 Pros-beta-5R1 Pros25 Pros26.4 Pros26S Pros26S-RS6A Pros28.1 Pros28.1A Pros28.1B Pros29 Pros35 Pros45 Pros54 ProsMA5 Prosalpha1 Prosalpha2 Prosalpha3 Prosalpha4 Prosalpha4T1 Prosalpha4T2 Prosalpha5 Prosalpha6 Prosalpha7 Prosb4 Prosbeta Prosbeta 2 Prosbeta1 Prosbeta2 Prosbeta2R1 Prosbeta2R2 Prosbeta3 Prosbeta4 Prosbeta5 Prosbeta5R Prosbeta5R1 Prosbeta5R1-RA Prosbeta5R2 Prosbeta7 Psmb2 Q7KMQ0_DROME REG REGgamma RPN1 RPN5 RPT5 Rel Rpn1 Rpn10 Rpn11 Rpn12 Rpn2 Rpn3 Rpn4 Rpn5 Rpn6 Rpn7 Rpn8 Rpn9 Rpn94 Rpt1 Rpt2 Rpt3 Rpt3-RA Rpt4 Rpt5 Rpt6 S10b S11 S14 S2 S6 S6' S6B S7 TBP-1 TBP7 Tbp-1 Tbp1 Ug anon-AE003657.1 anon-EST:fe1E6 anon-EST:fe1G6 anon-WO0118547.116 anon-WO0118547.90 anon-WO0153538.10 anon-WO0153538.8 anon-WO0153538.9 b2 beta 2 beta-1 beta-2 beta-4 beta-5 beta1 beta2 beta2R1 beta2R2 beta2_dm beta4 beta5 beta5R1 beta5R2 cact dREG dREGgamma dReg dReggamma dRpn12 dRpt1 dRpt5 dbeta5 dl ird5 key l(1)G0052 l(1)G0114 l(1)G0227 l(1)G0345 l(2)05070 l(2)05070-RA l(2)05643 l(2)43Ed l(3)04210 l(3)DTS7 l(3)S071806 l(3)S071806b p30 p39A p42D p48A p48B p50 p55 p97 prosbeta prosbeta1 prosbeta2 rpn1 rpn12 rpn5 rpn9 rpt3 tbp-1 yip5	Drosophila melanogaster (fruit fly)
Synthesis of PS	Phosphatidylserine synthase	Q9VPD3	Pss l(3)77CDf ptdss1	Drosophila melanogaster (fruit fly)
SHC-mediated cascade:FGFR1	DShc protein Fibroblast growth factor receptor homolog 2 Fibroblast growth factor Growth factor receptor-bound protein 2 LP05116p Protein son of sevenless Ras-like protein 1	P08646 P26675 Q08012 Q09147 Q9V3C8 Q9VDT9 Q9VV98	BNL Bnl Branchless D-Shc DFGF DSHC DmBnl Dmel\CG3715 Dmel\CG4608 Dmel\CG9701 E(sev)2B FGF FR2 Grb2 HD-311 Ras1 Ras85D Shc Shc-RA Sos Tk2 bnl btl dFGF dShc drk dshc klotho l(3)06916 l(3)neo52 shc	Drosophila melanogaster (fruit fly)
pre-mRNA splicing	116 kDa U5 small nuclear ribonucleoprotein component AT22957p AT27789p ATP-dependent RNA helicase DHX15 homolog ATP-dependent RNA helicase DHX8 ATP-dependent RNA helicase WM6 ATP-dependent RNA helicase abstrakt ATP-dependent RNA helicase Acinus, isoform A Cell division cycle 5, isoform A Cwc25 DNA-directed RNA polymerase II subunit RPB11 DNA-directed RNA polymerase II subunit RPB1 DNA-directed RNA polymerase II subunit RPB2 DNA-directed RNA polymerase II subunit RPB7 DNA-directed RNA polymerase II subunit RPB9 DNA-directed RNA polymerase II subunit Rpb4 DNA-directed RNA polymerases I, II, and III subunit RPABC2 DNA-directed RNA polymerases I, II, and III subunit RPABC3 DNA-directed RNA polymerases I, II, and III subunit RPABC5 EG Eukaryotic initiation factor 4A-III FI04407p FI21110p1 FI21118p1 FI21285p1 G patch domain-containing protein 1 homolog GEO11084p1 GEO11163p1 GH07456p GH13594p GM02612p GM13767p Gastrulation defective protein 1 homolog General transcription factor IIF subunit 1 General transcription factor IIF subunit 2 Heat shock 70 kDa protein cognate 4 Hephaestus, isoform Y Heterogeneous nuclear ribonucleoprotein K, isoform C Histone deacetylase complex subunit SAP18 L.2.35Df LD03179p LD14179p LD21442p LD21931p LD23870p LD24662p LD24793p LD29830p LD32469p LD37574p LD38910p LD39850p LD40489p LD41978p MIP04834p Mushroom-body expressed, isoform K NKAP family protein CG6066 Nuclear cap-binding protein subunit 1 Nuclear cap-binding protein subunit 2 PHD finger-like domain-containing protein 5A Peptidyl-prolyl cis-trans isomerase Peptidyl-prolyl cis-trans isomerase Peptidyl-prolyl cis-trans isomerase Pinin, isoform B Poly(U)-binding-splicing factor half pint Pre-mRNA processing factor 8 Pre-mRNA-processing factor 19 Pre-mRNA-splicing factor 18 Pre-mRNA-splicing factor CWC22 homolog Pre-mRNA-splicing factor RBM22 Pre-mRNA-splicing factor SPF27 Pre-mRNA-splicing factor Slu7 Pre-mRNA-splicing factor Syf2 Pre-mRNA-splicing factor syf1 homolog Probable U2 small nuclear ribonucleoprotein A' Probable small nuclear ribonucleoprotein E Probable small nuclear ribonucleoprotein G Probable small nuclear ribonucleoprotein Sm D1 Probable small nuclear ribonucleoprotein Sm D2 Protein BUD31 homolog Protein CASC3 Protein CWC15 homolog Protein FAM50 homolog Protein crooked neck Protein mago nashi Puff-specific protein Bx42 RE31520p RH64960p RING-type E3 ubiquitin transferase RNA helicase RNA helicase RNA helicase RNA-binding protein 1 RNA-binding protein 8A RNA-binding protein cabeza RNA-binding protein squid RPB5 homolog RRM domain-containing protein STING ER exit protein Serine/arginine-rich splicing factor x16 Serrate RNA effector molecule homolog Small nuclear ribonucleoprotein F Small nuclear ribonucleoprotein Sm D3 Small nuclear ribonucleoprotein-associated protein B Smooth, isoform T Splicing factor 45 Splicing factor Cactin Splicing factor YJU2 Survival of motor neuron-related-splicing factor 30 Syncrip, isoform Q Transformer-2 sex-determining protein U1 small nuclear ribonucleoprotein A U2 snRNP-associated SURP motif-containing protein U5 small nuclear ribonucleoprotein 200 kDa helicase Uncharacterized protein, isoform C Uncharacterized protein, isoform D Uncharacterized protein, isoform D Zinc finger protein 830	A0A023GRW3 A0A0B4K6W9 A0A0B4K7I2 A0A0B4KH64 A0A0B4KHI4 A1Z8U0 A1Z9G2 A1Z9L3 A1ZBW0 A8JQW3 E1JGL8 M9NEH9 O44437 O76861 O97183 O97454 P04052 P08266 P11147 P17886 P19018 P36958 P39736 P41900 P43332 P49028 Q02427 Q05856 Q05913 Q08473 Q24297 Q24320 Q27268 Q27294 Q59E33 Q6IGE3 Q7JVH0 Q7JZF5 Q7K1V1 Q7K231 Q7K3M5 Q7K4N3 Q7KLW9 Q7KSN8 Q7KU81 Q7PL83 Q8MKJ6 Q8MZI3 Q8T6B9 Q95RB1 Q95RE4 Q95RI7 Q960Q8 Q9V3B6 Q9V3C0 Q9V3E7 Q9V3L6 Q9V3T8 Q9V3V0 Q9V3W7 Q9V412 Q9V437 Q9V4Q8 Q9V535 Q9V5Q4 Q9V9K7 Q9VAC7 Q9VAQ7 Q9VAX8 Q9VAY6 Q9VAY7 Q9VB74 Q9VBY5 Q9VC49 Q9VCE2 Q9VD52 Q9VEA5 Q9VEX9 Q9VF55 Q9VFB5 Q9VGH5 Q9VGJ3 Q9VH00 Q9VHC0 Q9VHJ7 Q9VHS8 Q9VHV6 Q9VI10 Q9VJ12 Q9VJ87 Q9VJE4 Q9VL71 Q9VLV5 Q9VMC8 Q9VNZ3 Q9VPL0 Q9VPY4 Q9VQF5 Q9VQZ5 Q9VR29 Q9VR99 Q9VU02 Q9VU43 Q9VUA0 Q9VUV9 Q9VXE0 Q9VXW2 Q9VY54 Q9VYE3 Q9VYQ9 Q9W0A9 Q9W0B6 Q9W0Q2 Q9W0R0 Q9W1H3 Q9W1J3 Q9W2N6 Q9XYZ6 Q9Y134	10Ba 110/46 152117_at 154911_at 9G8 A1Z8U0 AI945337 ALY ALYREF ASF ASF/SF2 Acn Aly Ars2 BCAS2 BEST:LP03871 BG:DS00941.10 BG:DS09217.2 BL BP1040 BP1047 Ba Bancal BcDNA.LD02793 BcDNA:GH01073 BcDNA:GH07290 BcDNA:GH10856 BcDNA:HL01868 BcDNA:HL07910 BcDNA:LD02793 BcDNA:LD24793 BcDNA:RE61564 BcDNA:SD23244 Bin1 Bl Brr2 Btz Bx42 CDC40 CG10437 CG12259 CG1375 CG1405 CG14058 CG14729 CG14730 CG15432-RA CG15494 CG15525-RA CG15747-RA CG18610 CG18656 CG2094 CG2290 CG2685-RA CG32168 CG33277 CG33279 CG33522-RA CG4887-RA CG5477 CG5542 CG5543 CG6066 CG6572 CG6615 CG6626 CG7483 CG8833 CT36969 CWC25 CYC4 Cbp20 Cbp80 Cdc5 Cdc5Dm Cwc25 Cypl D-rpII33 D25 DEK Dbp25F DebB Dhx15 DmPTB DmREF1 DmRH29 DmRH5 DmRPB5 Dmel\CG10077 Dmel\CG10473 Dmel\CG1101 Dmel\CG11184 Dmel\CG11246 Dmel\CG11274 Dmel\CG11777 Dmel\CG11839 Dmel\CG11964 Dmel\CG11979 Dmel\CG12818 Dmel\CG12878 Dmel\CG13425 Dmel\CG13892 Dmel\CG14641 Dmel\CG14718 Dmel\CG15432 Dmel\CG15525 Dmel\CG15747 Dmel\CG1639 Dmel\CG16788 Dmel\CG17249 Dmel\CG17454 Dmel\CG17540 Dmel\CG17838 Dmel\CG1796 Dmel\CG2685 Dmel\CG2843 Dmel\CG30122 Dmel\CG31000 Dmel\CG31155 Dmel\CG31368 Dmel\CG3225 Dmel\CG32604 Dmel\CG33522 Dmel\CG34186 Dmel\CG3436 Dmel\CG3511 Dmel\CG4152 Dmel\CG42458 Dmel\CG4602 Dmel\CG4849 Dmel\CG4887 Dmel\CG4896 Dmel\CG4980 Dmel\CG5213 Dmel\CG5442 Dmel\CG5519 Dmel\CG5654 Dmel\CG5808 Dmel\CG5986 Dmel\CG6011 Dmel\CG6015 Dmel\CG6227 Dmel\CG6905 Dmel\CG6946 Dmel\CG6987 Dmel\CG7437 Dmel\CG7747 Dmel\CG7885 Dmel\CG7974 Dmel\CG8383 Dmel\CG8435 Dmel\CG8441 Dmel\CG8877 Dmel\CG9218 Dmel\CG9346 Dmel\CG9667 Dx16 E-2e EC2-11 EFTUD2 EG:100G10.1 EP764 EP784 FBgn0037737 GPB Gbp Glo HEPH HNPNPC Hel25E Heph HnRNP-K Hrb57A Hsc4 Hsc70-4 ISY1 L(1)10Bb L(2)35Df LD11002 MRE17 MUB Mtr4 Mub PRP19 PTB Phf5a Pnn Pol II Pol II RPII33 PolII PolIIo Polr2A Polr2B Polr2C Polr2D Polr2E Polr2F Polr2G Polr2H Polr2I Polr2J Polr2K Polr2L Prp16 Prp18 Prp19 Prp22 Prp5 Prp8 Ptb Q18 RBM17 REF1 RNA Pol II RNA pol II RNA polII RNAP RNPS1 RP140 RPB1 RPB12 RPB2 RPB3 RPB5 RPB6 RPB7 RPB8 Rbp1 Rbp11 Rbp3 Ref1 RnpS1 Rnps1 RpABC14 RpII140 RpII15 RpII18 RpII215 RpII33 Rpb10 Rpb11 Rpb12 Rpb3 Rpb4 Rpb5 Rpb7 Rpb8 Rpll33 SAF-A SAP18 SARFH SC-35 SC35 SF2 SNRPG SPF30 SPF45 SRM160 SRP54 SRSF1 SRm160 SRp30 SRp54 Sc35 Slu7 Sm SmB SmD1 SmD2 SmD3 SmE SmF SmG Snu114 Spf30 Spf45 Srp54 Srrm1 Steep1 Syf2 Syp TANGO4 TFIIF30 Tango4 TfIIFalpha TfIIFbeta U2A UKL UPF3 Upf3 Upf3-RB WM6 Y14 YPS Yps Znf830 abs acn aly anon-EST:Liang-2.16 anon-EST:Posey284 anon-WO0118547.328 anon-WO0118547.613 anon-WO0172774.33 anon-WO0172774.35 anon-WO0172774.36 anon-WO0172774.37 bl bl-RC br17 br44 btz c12.1 cactin caz cdc5 cdc5-like cef1 cg10077 cg1101 cg11777 cg1405 cg14641 cg14718 cg15432 cg16788 cg17838 cg18656 cg3225 cg4152 cg42458 cg4887 cg4896 cg5213 cg5442 cg5808 cg6227 cg6946 cg6987 cg9346 clone 2.16 crn cycl cypl dASF dAcn dBCAS2 dMtr4 dPTB dPnn dPrp19 dRBM17 dRpb7 dSC35 dSF2/ASF dSPF45 dSRp30 dSRp54 dUPF3 dacn dhnRNP K dmPTB dmREF1 dmSF2/p28 dxl6 eEF2 eftud2 ema fand fas fs(1)1621 glo guf2 hel heph hfp hkl hnRNP I hnRNP K hnRNP U hnRNP-A1L hrp40 l(1)10Bb l(1)G0007 l(1)G0028 l(1)G0103 l(1)G0169 l(1)G0176 l(1)G0308 l(1)G0416 l(1)G0476 l(1)G0491 l(1)G14 l(1)GLM14 l(2)05338 l(2)07838 l(2)34Dg l(2)35Df l(2)37Ba l(2)br17 l(2)br44 l(2)k05605 l(2)k08305 l(2)k14422 l(2)k14423 l(3)02267 l(3)03429 l(3)03806 l(3)04093 l(3)72Ab l(3)S011046 l(3)S11046 l(3)j11B9 l(3)j6B10 l(3)j8B3 l.2.35Df l34Dg lethal(1)10Bb lethal(2)35Df liz maca mago mgn mub ncm p28/SF2 p45 p57 p67 p67-K p75 p90 pUf68 pea pol II polII prp16 prp17 prp18 prp19 prp8 ptb ref1 rnps1 rpII33 rpb3 sc35 scaf6 sm smo snRNP2 snRNP69D snf spf-45 spf45 sqd srp54 syp tango4 tra-2 tra2 tsu upf3 wkl x16 xl6 yps	Drosophila melanogaster (fruit fly)
SIRT1 negatively regulates rRNA expression	Histone H2A.v Histone H2A Histone H2A Histone H2B Histone H3.3A Histone H3.3B Histone H3 Histone H4 Histone-lysine N-methyltransferase Su(var)3-9 NAD-dependent histone deacetylase sirtuin-1 Ribosomal RNA-processing protein 8	C0HL66 C0HL67 P02283 P02299 P08985 P45975 P84040 P84051 Q4AB57 Q7K2B0 Q9VK34	CG7137 Dmel\CG33853 Dmel\CG33856 Dmel\CG33859 H2AvD H2a H4 H4r His2A His2A:CG31618 His2A:CG33808 His2A:CG33814 His2A:CG33817 His2A:CG33820 His2A:CG33823 His2A:CG33826 His2A:CG33829 His2A:CG33832 His2A:CG33835 His2A:CG33838 His2A:CG33841 His2A:CG33844 His2A:CG33847 His2A:CG33850 His2A:CG33853 His2A:CG33856 His2A:CG33859 His2A:CG33862 His2A:CG33865 His2Av His2AvD His2B His2B:CG17949 His2B:CG33868 His2B:CG33870 His2B:CG33872 His2B:CG33874 His2B:CG33876 His2B:CG33878 His2B:CG33880 His2B:CG33882 His2B:CG33884 His2B:CG33886 His2B:CG33888 His2B:CG33890 His2B:CG33892 His2B:CG33894 His2B:CG33896 His2B:CG33898 His2B:CG33900 His2B:CG33902 His2B:CG33904 His2B:CG33906 His2B:CG33908 His2B:CG33910 His3 His3.3A His3.3B His3:CG31613 His3:CG33803 His3:CG33806 His3:CG33809 His3:CG33812 His3:CG33815 His3:CG33818 His3:CG33821 His3:CG33824 His3:CG33827 His3:CG33830 His3:CG33833 His3:CG33836 His3:CG33839 His3:CG33842 His3:CG33845 His3:CG33848 His3:CG33851 His3:CG33854 His3:CG33857 His3:CG33860 His3:CG33863 His3:CG33866 His4 His4:CG31611 His4:CG33869 His4:CG33871 His4:CG33873 His4:CG33875 His4:CG33877 His4:CG33879 His4:CG33881 His4:CG33883 His4:CG33885 His4:CG33887 His4:CG33889 His4:CG33891 His4:CG33893 His4:CG33895 His4:CG33897 His4:CG33899 His4:CG33901 His4:CG33903 His4:CG33905 His4:CG33907 His4:CG33909 His4r KMT1 Sir2 Sirt1 Su(var)3-9	Drosophila melanogaster (fruit fly)
RHOH GTPase cycle	Amino acid transporter Anion exchange protein Armadillo segment polarity protein Band 7 protein CG42540 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex GH01724p LD16419p Probable Rho GTPase-activating protein CG5521 Protein FAM91A1 Protein NipSnap Putative inactive tyrosine-protein kinase Wsck Ragulator complex protein LAMTOR1 Ras-related protein Rab7 Ras-related protein Rac1 Ras-related protein Rac2 Rho-associated protein kinase Serine/threonine-protein kinase PAK mbt Serine/threonine-protein kinase Pak Transitional endoplasmic reticulum ATPase TER94 Tyrosine-protein kinase Src64B Tyrosine-protein kinase Vang-like protein non-specific serine/threonine protein kinase	A0A0B4KEN4 A0A0B4KGS4 A0A6H2EJK0 O76742 P00528 P18824 P40792 P48554 P83097 Q7K3Z3 Q7KN62 Q8INJ8 Q8IPI3 Q9VB98 Q9VI13 Q9VW59 Q9VW73 Q9VXE3 Q9VXE5 Q9VXK0 Q9VXY3 Q9VZA4 Q9XZ12	153385_at AF001784 CG14184-RB CG17309 CG31906 CG32852 CG42540 CG4675 CG5521 CSK Csk D-Pak3 DCsk DPAK DPAK3 DPak3 DROK DRhk DRok Dbct Dglt-1 Dglut-1 DmPAK3 Dmel\CG11139 Dmel\CG14184 Dmel\CG14895 Dmel\CG3747 Dmel\CG42253 Dmel\CG42317 Dmel\CG5599 Dmel\CG7600 Dmel\CG7823 Dmel\CG8075 Dmel\CG9774 Dpak1 Dpak3 Drok EAAT EAAT1 Eaat 1 Eaat1 GLUT Lamtor1 MRLC NDAE1 Ndae-1 Ndae1 Nipsnap PAK-3 PAK3 PaK3 Pak Pak3 ROCK ROCK-1 ROCK1 ROCK2 ROK ROKalpha/beta Rab-7 Rab-r7 Rab7 Rab7A Rac1 Rac2 RacA RacB Rhk RhoGDI RhoK Rock Rok Rok/ROCK Src Src1 Src64B Stb Stbm TER94 VANG VCP Vang Vang/Stbm Wsck anon-WO0118547.216 anon-WO0118547.285 anon-WO0118547.633 anon-WO0257455.13 arm csk d-Csk dCSK dCsk dEAAT dEAAT1 dEaat1 dPAK3 dROK dRok dcsk dp18 dp47 dpak3 drok eaat1 flik l(2)k10316 l(3)S017909 l(3)j1D8 mbt ndae1 p18 p47 pak3 rok rok-RA stb stbm stbm/vang strabismus/Van Gogh vang vang/stbm vangogh/strabismus	Drosophila melanogaster (fruit fly)
HSF1 activation	14-3-3 protein epsilon Elongation factor 1-alpha 1 Elongation factor 1-alpha 2 Heat shock factor protein Heat shock protein 83 Histone deacetylase 6, isoform G Prostaglandin E synthase 3 homolog Transitional endoplasmic reticulum ATPase TER94	M9PJN5 P02828 P05303 P08736 P22813 P92177 Q7KN62 Q9VH95	14-3-3e 14-3-3epsilon DHDAC2 DmHDAC2 Dmel\CG6170 EF1B EF1a Ef1alpha100E Ef1alpha48D F1 F2 HDAC HDAC2 HDAC6 Hsf Hsp82 Hsp83 Hsp90 SR3-9 TER94 VCP dHDAC2 dHDAC6 dmHDA404 eEF1alpha1 eEF1alpha2 hdac6 p23	Drosophila melanogaster (fruit fly)
Pyruvate metabolism	AT14039p GH17657p GH26960p L-lactate dehydrogenase MIP04751p Malic enzyme like-2, isoform A Malic enzyme Malic enzyme Malic enzyme Pyruvate carboxylase Pyruvate kinase Pyruvate kinase Pyruvate kinase Uncharacterized protein, isoform A Uncharacterized protein, isoform B Uncharacterized protein Voltage-dependent anion-selective channel Voltage-dependent anion-selective channel alanine transaminase hydroxyacylglutathione hydrolase lactoylglutathione lyase pyruvate kinase	A1Z6X6 A1Z9F8 A1ZAF6 E1JIZ4 O62619 Q0E9E2 Q7K3R0 Q86NT5 Q8IPU3 Q94920 Q95028 Q9VD23 Q9VDE2 Q9VFG4 Q9VG31 Q9VKP2 Q9VKP3 Q9VKP4 Q9VNZ9 Q9VQH0 Q9VVH0 Q9VYD9	ALT BEST:LP07660 BcDNA BcDNA:GH06348 CG17139-RA CG30097 CG31722 CG31722-A CG31722-B DmPorin2 Dmel\CG10120 Dmel\CG11249 Dmel\CG12229 Dmel\CG13334 Dmel\CG1516 Dmel\CG1640 Dmel\CG1707 Dmel\CG17137 Dmel\CG17139 Dmel\CG17140 Dmel\CG2964 Dmel\CG4365 Dmel\CG5793 Dmel\CG5889 Dmel\CG7069 Dmel\CG7362 Dmel\CG7848 Dmel\CG7964 Dmel\CG7969 FBgn0038858 Glo1 Imp-L3 ImpL3 LP07660.3prime Ldh MDH ME MEN Mdh Mdh-NADP Me Men Men-b Menl-1 Menl-2 NEST:bs27e02 PC PCB POR-1 Porin 2 Porin2 Porin2 _z FBgn0069354 PyK Q0E9E2_DROME VDAC anon-EST:Posey79 anon-WO0118547.278 cg1640 dPC glo1 mem men pcb porin porin 2 tzn	Drosophila melanogaster (fruit fly)
Regulation of innate immune responses to cytosolic DNA	GH17761p Meiotic P26, isoform F Polyubiquitin Stimulator of interferon genes protein homolog Ubiquitin-like domain-containing protein Ubiquitin-ribosomal protein eS31 fusion protein	A0A0B4LFY9 A0A4D6K5H4 P0CG69 P15357 Q9W418 R9PY16	AF145661 BcDNA:GH10646 CG18282 CR11700 CR32744 DmUb DmUbi-p5E Dmel\CG11700 Dmel\CG12218 Dmel\CG32744 ESTS:143G11T ESTS:199A6T MEI-P26 Mei-P26 RpS27A Sting UB UB3-D UBI-F80 Ub Ubi Ubi-m Ubi-p5E Ubi-p5E5 Ubi-p63E Ubiq Ubiquitin anon-sts41 mei-P26 mei-p26 meiP26 poly-ub	Drosophila melanogaster (fruit fly)

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