GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	March 20, 2024
ECODAB	April 1, 2019

Displaying entries **51 - 75** of **597** in total

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Pathway Name	Protein Name	UniProt ID	Gene Symbol ▼	Organism
Adaptor protein complex binds to TL receptor at the plasma membrane	LD20892p Protein Tube Protein spaetzle Protein toll Zinc finger protein weckle	P08953 P22812 P48607 Q7K105 Q9VJN5	DMMYD88 DmMyD88 DmMyd88 Dmel\CG2078 EP(2)2535 Kra LD20892 MYD88 MyD88 Myd88 Myd88F Tl dMYd88 dMyD88 dMyd88 kra l(2)35Ea myd88 spz tub tube wek	Drosophila melanogaster (fruit fly)
Activated PLL kinase is autophosphorylated in the TL receptor 'signalling complex'	LD20892p Protein Tube Protein spaetzle Protein toll Serine/threonine-protein kinase pelle Zinc finger protein weckle	P08953 P22812 P48607 Q05652 Q7K105 Q9VJN5	DMMYD88 DmMyD88 DmMyd88 Dmel\CG2078 EP(2)2535 Kra LD20892 MYD88 MyD88 Myd88 Myd88F Tl dMYd88 dMyD88 dMyd88 kra l(2)35Ea myd88 pll spz tub tube wek	Drosophila melanogaster (fruit fly)
PLL kinase binds to TUB in the TL receptor 'signalling complex'	LD20892p Protein Tube Protein spaetzle Protein toll Serine/threonine-protein kinase pelle Zinc finger protein weckle	P08953 P22812 P48607 Q05652 Q7K105 Q9VJN5	DMMYD88 DmMyD88 DmMyd88 Dmel\CG2078 EP(2)2535 Kra LD20892 MYD88 MyD88 Myd88 Myd88F Tl dMYd88 dMyD88 dMyd88 kra l(2)35Ea myd88 pll spz tub tube wek	Drosophila melanogaster (fruit fly)
Formation of the trans-membrane 'signalling complex'	LD20892p Protein Tube Protein spaetzle Protein toll Serine protease easter Serine protease gd Serine protease inhibitor 27A Serine protease snake Spaetzle-processing enzyme	O62589 P05049 P08953 P13582 P22812 P48607 Q7K105 Q9V3N1 Q9VCJ8	DMMYD88 DmMyD88 DmMyd88 Dmel\CG2078 EP(2)2535 Kra LD20892 MYD88 MyD88 Myd88 Myd88F SP4 SPE Spn27A Tl c-SP4 dMYd88 dMyD88 dMyd88 ea gd kra myd88 snk spz tub tube	Drosophila melanogaster (fruit fly)
DL and DIF homodimers bind to TUB and phosphorylated PLL in the TL receptor 'signalling complex'	Dorsal-related immunity factor Dif Embryonic polarity protein dorsal LD20892p NF-kappa-B inhibitor cactus Protein Tube Protein spaetzle Protein toll Serine/threonine-protein kinase pelle Zinc finger protein weckle	P08953 P15330 P22812 P48607 P98149 Q03017 Q05652 Q7K105 Q9VJN5	DMMYD88 Dif DmMyD88 DmMyd88 Dmel\CG2078 EP(2)2535 Kra LD20892 MYD88 MyD88 Myd88 Myd88F Tl cact dMYd88 dMyD88 dMyd88 dl kra l(2)35Ea myd88 pll spz tub tube wek	Drosophila melanogaster (fruit fly)
Phosphorylated CACT, DL and DIF homodimers dissociate from the TL receptor 'signalling complex'	Dorsal-related immunity factor Dif Embryonic polarity protein dorsal LD20892p NF-kappa-B inhibitor cactus Protein Tube Protein spaetzle Protein toll Serine/threonine-protein kinase pelle Zinc finger protein weckle	P08953 P15330 P22812 P48607 P98149 Q03017 Q05652 Q7K105 Q9VJN5	DMMYD88 Dif DmMyD88 DmMyd88 Dmel\CG2078 EP(2)2535 Kra LD20892 MYD88 MyD88 Myd88 Myd88F Tl cact dMYd88 dMyD88 dMyd88 dl kra l(2)35Ea myd88 pll spz tub tube wek	Drosophila melanogaster (fruit fly)
DL and DIF homodimers complexed with CACT are all phosphorylated in the TL receptor 'signalling complex'	Dorsal-related immunity factor Dif Embryonic polarity protein dorsal LD20892p NF-kappa-B inhibitor cactus Protein Tube Protein spaetzle Protein toll Serine/threonine-protein kinase pelle Zinc finger protein weckle	P08953 P15330 P22812 P48607 P98149 Q03017 Q05652 Q7K105 Q9VJN5	DMMYD88 Dif DmMyD88 DmMyd88 Dmel\CG2078 EP(2)2535 Kra LD20892 MYD88 MyD88 Myd88 Myd88F Tl cact dMYd88 dMyD88 dMyd88 dl kra l(2)35Ea myd88 pll spz tub tube wek	Drosophila melanogaster (fruit fly)
Formation and asymmetric localisation of transmembrane complexes	Diego, isoform A Frizzled Protein prickle Protocadherin-like wing polarity protein stan Segment polarity protein dishevelled Vang-like protein	A1Z6W3 O45030 P18537 P51140 Q7JUF2 Q9V5N8	DGO Dgo Dmel\CG12342 EP(2)2619 EP2619 Vang dgo dsh fmi fz pk stan stbm	Drosophila melanogaster (fruit fly)
GRB2 events in ERBB2 signaling	Epidermal growth factor receptor Growth factor receptor-bound protein 2 Protein son of sevenless Protein vein Ras-like protein 1	P04412 P08646 P26675 Q08012 Q94918	DER E(sev)2B Egfr Grb2 Ras1 Ras85D Sos c-erbB ddd drk top vn	Drosophila melanogaster (fruit fly)
PI3K events in ERBB4 signaling	Epidermal growth factor receptor Pi3K21B, isoform B Protein vein	P04412 Q7KTZ2 Q94918	DER Dmel\CG2699 Dp60 Egfr P60 PI(3)K PI3 kinase PI3K PI3K-p60 PI3K-reg PI3K21B PI[[3]]K Pi3K Pi3K21B Pi3Kp60 Pi3k21B c-erbB dP60 dPI3K ddd deltap60 dp60 droPIK57 p60 p85 top vn	Drosophila melanogaster (fruit fly)
EGFR Transactivation by Gastrin	Epidermal growth factor receptor Growth factor receptor-bound protein 2 Matrix metalloproteinase 1, isoform C Matrix metalloproteinase-2 Protein kinase C, brain isozyme Protein son of sevenless Ras-like protein 1	P04412 P05130 P08646 P26675 Q08012 Q8MPP3 Q9W122	DER Dm1-MMP Dmel\CG4859 E(sev)2B Egfr Grb2 MMP MMP-1 MMP1 MMp1 Mmp 1 Mmp-1 Mmp1 Mmp2 PKC1 Pkc53E Ras1 Ras85D Sos c-erbB dMMP1 dm1-MMP dmmp1 drk l(2)k04809 mmp-1 mmp1 top	Drosophila melanogaster (fruit fly)
Nuclear signaling by ERBB4	Epidermal growth factor receptor Estrogen-related receptor splice variant Gamma-secretase subunit Aph-1 Gamma-secretase subunit pen-2 Knirps-related protein Nicastrin Presenilin homolog Protein embryonic gonad Signal transducer and transcription activator Tyrosine-protein kinase Src64B WW domain-containing oxidoreductase Zygotic gap protein knirps	O02194 P00528 P04412 P10734 P13054 P15370 Q24151 Q86BE9 Q8WS79 Q9VC27 Q9VLU5 Q9VQG2	DER Derr Dmel\CG7404 ERR Egfr MARE NCSTN NR0A1 NR0A2 NR0A3 NR3B4 Nct PS PSF Psn Src1 Src64B Stat Stat92E Wwox aph-1 c-erbB dERR eg egon kni knrl mrL pen-2 spry top	Drosophila melanogaster (fruit fly)
Clearance of dopamine	Sodium-dependent dopamine transporter	Q7K4Y6	DAT fmn	Drosophila melanogaster (fruit fly)
PCP/CE pathway	Dishevelled associated activator of morphogenesis, isoform D Frizzled Protein Wnt-4 Protein Wnt-5 Protein wingless Ras-like GTP-binding protein Rho1 Ras-related protein Rac1 Ras-related protein Rac2 Segment polarity protein dishevelled	M9MSM5 P09615 P18537 P28466 P40589 P40792 P48148 P48554 P51140	DAAM DAAM1 Daam Dmel\CG14622 EG:114D9.2 Rac1 Rac2 RacA RacB Rho1 WNT-5 Wnt-3 Wnt-4 Wnt4 Wnt5 anon-EST:Posey148 dDAAM dDaam daam dsh fz wg	Drosophila melanogaster (fruit fly)
Activation of RHO1 by FZ:DSH complex	Diego, isoform A Dishevelled associated activator of morphogenesis, isoform B Frizzled Protein prickle Protocadherin-like wing polarity protein stan Ras-like GTP-binding protein Rho1 Rho-associated protein kinase Segment polarity protein dishevelled Vang-like protein	A1Z6W3 O45030 P18537 P48148 P51140 Q7JUF2 Q8IRY0 Q9U779 Q9V5N8	DAAM DAAM1 DGO Daam Dgo Dmel\CG12342 Dmel\CG14622 EG:114D9.2 EP(2)2619 EP2619 Rhk Rho1 Rok Vang anon-EST:Posey148 dDAAM dDaam daam dgo dsh fmi fz pk rok stan stbm	Drosophila melanogaster (fruit fly)
ESR-mediated signaling	Estrogen-related receptor splice variant FK506-binding protein 59 Heat shock protein 83 Knirps-related protein Prostaglandin E synthase 3 homolog Protein embryonic gonad Zygotic gap protein knirps protein-serine/threonine phosphatase	P02828 P10734 P13054 P15370 Q8WS79 Q9VH81 Q9VH95 Q9VL78	D3 Derr DmPP5 DmPpp5-85E Dmel\CG7404 Dmel\CG8402 ERR Fkbp59 Hsp82 Hsp83 Hsp90 NR0A1 NR0A2 NR0A3 NR3B4 PP5 PP5 85E PPP5 Pp5-85E PpD3 dERR eg egon kni knrl p23 spry	Drosophila melanogaster (fruit fly)
Insulin receptor signalling cascade	DShc protein Growth factor receptor-bound protein 2 Protein son of sevenless	P26675 Q08012 Q9V3C8	D-Shc DSHC Dmel\CG3715 E(sev)2B Grb2 Shc Shc-RA Sos dShc drk dshc shc	Drosophila melanogaster (fruit fly)
Signaling by CSF3 (G-CSF)	DShc protein Growth factor receptor-bound protein 2 Protein daughter of sevenless Putative inactive tyrosine-protein kinase Wsck Ras-like protein 1 Tyrosine-protein kinase Src64B Tyrosine-protein kinase hopscotch	P00528 P08646 P83097 Q08012 Q24592 Q9V3C8 Q9VZZ9	D-Shc DSHC Dmel\CG3715 E(sev)2B Grb2 HD-160 Ras1 Ras85D Shc Shc-RA Src1 Src64B Wsck dShc dos drk dshc hop shc	Drosophila melanogaster (fruit fly)
SHC1 events in ERBB4 signaling	DShc protein Epidermal growth factor receptor Growth factor receptor-bound protein 2 Protein son of sevenless Protein vein Ras-like protein 1	P04412 P08646 P26675 Q08012 Q94918 Q9V3C8	D-Shc DER DSHC Dmel\CG3715 E(sev)2B Egfr Grb2 Ras1 Ras85D Shc Shc-RA Sos c-erbB dShc ddd drk dshc shc top vn	Drosophila melanogaster (fruit fly)
Repression of WNT target genes	C-terminal-binding protein Protein groucho Protein pangolin, isoform J	O46036 P16371 Q8IMA8	CtBP E(spl)m9/m10 TCF gro pan	Drosophila melanogaster (fruit fly)
Gastrin-CREB signalling pathway via PKC and MAPK	Cyclic AMP response element-binding protein B Mitogen-activated protein kinase ERK-A Ribosomal protein S6 kinase II, isoform A	P40417 Q9VR61 Q9VWW0	CrebB CrebB-17A D-RSK Dmel\CG17596 ERKa MAPK RSK Rsk S6KII S6kII dRSK dRsk ign rl rsk rsk2	Drosophila melanogaster (fruit fly)
Activation of Matrix Metalloproteinases	Cathepsin L Furin-like protease 1, isoforms 1/1-X/2 Matrix metalloproteinase 1, isoform C Matrix metalloproteinase-2 RH50269p Tissue inhibitor of metalloproteinase	P26016 Q8MPP3 Q95029 Q9VH14 Q9VJD7 Q9W122	Cp1 Dm1-MMP Dmel\CG4859 Dmel\CG6639 Fur1 MMP MMP-1 MMP1 MMp1 Mmp 1 Mmp-1 Mmp1 Mmp2 SPH93 Timp c-SPH93 cSPH93 dMMP1 dm1-MMP dmmp1 fs(2)50Ca l(2)k04809 mmp-1 mmp1	Drosophila melanogaster (fruit fly)
Transport of bile salts and organic acids, metal ions and amine compounds	Choline transporter-like 1 Choline transporter-like 2 High-affinity choline transporter 1 RH04535p	Q9VAP3 Q9VE46 Q9VXV4 Q9VZE7	ChT Ctl1 Ctl2 Dmel\CG11655	Drosophila melanogaster (fruit fly)
DARPP-32 events	3',5'-cyclic-AMP phosphodiesterase, isoform I UT01108p cAMP-dependent protein kinase catalytic subunit 1 cAMP-dependent protein kinase catalytic subunit 2 cAMP-dependent protein kinase type I regulatory subunit cAMP-dependent protein kinase type II regulatory subunit	P12370 P16905 P16911 P81900 Q9VA47 Q9W4T4	CdkA CdkR DC0 DC1 Dmel\CG12069 Pka-C1 Pka-C2 Pka-R1 Pka-R2 Pka-like dnc pka-RII	Drosophila melanogaster (fruit fly)
Mitotic Prophase	Cyclin-dependent kinase 1 G2/mitotic-specific cyclin-B Mushroom body defect, isoform H	P20439 P23572 Q8IR55	Cdk1 CycB Dmel\CG12047 KS63 Mud NuMA NuMa cdc2 mud	Drosophila melanogaster (fruit fly)

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