GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	November 12, 2024
ECODAB	April 1, 2019

Displaying entries **26 - 50** of **270** in total

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Pathway Name	Protein Name	UniProt ID	Gene Symbol	Organism	GlyTouCan ID
G alpha (s) signalling events	5-hydroxytryptamine (serotonin) receptor 7, adenylate cyclase-coupled 5-hydroxytryptamine receptor 4 ADCYAP receptor type I Adenosine receptor A2b Adenylate cyclase activating polypeptide 1 Adrenoceptor beta 3 Amyloid protein Beta-2 adrenergic receptor Calcitonin gene-related peptide type 1 receptor Calcitonin Corticotropin releasing hormone Corticotropin-releasing factor receptor 1 Follitropin subunit beta G protein subunit beta 3 G protein subunit beta 4 G protein subunit gamma 13 G protein-coupled pituitary GHRH receptor G protein-coupled receptor 27 G protein-coupled receptor kinase G-protein coupled receptor 39 Glucagon-like peptide 1 receptor Glucagon-like peptide 2 receptor Glycoprotein hormones alpha chain Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 Guanine nucleotide-binding protein G(s) subunit alpha Guanine nucleotide-binding protein subunit gamma Guanine nucleotide-binding protein subunit gamma Guanine nucleotide-binding protein subunit gamma Guanine nucleotide-binding protein subunit gamma Guanine nucleotide-binding protein subunit gamma Histamine H2 receptor Melanocortin receptor 4 Melanocortin receptor 5 Melanocyte-stimulating hormone receptor Neuropeptide S receptor Neuropeptide S Parathyroid hormone-related protein Parathyroid hormone/parathyroid hormone-related peptide receptor Parathyroid hormone Phosphodiesterase Phosphodiesterase Pro-glucagon Prostaglandin D2 receptor Prostaglandin E receptor 2 Prostaglandin E2 receptor EP4 subtype Receptor activity modifying protein 2 Receptor activity-modifying protein 3 Somatoliberin Thyrotropin subunit beta VIP peptides VPAC2 receptor	A0A1D5P7A9 A0A1D5P7Q2 A0A1D5P7Z5 A0A1D5P8Y9 A0A1D5PKZ0 A0A1D5PLZ8 A0A1D5PP20 A0A3Q2TWD9 A0A3Q2TZX9 A0A3Q2U4U2 A0A3Q2U9J5 A0A3Q2UHX2 A1XWZ9 A2TH16 A7UH64 B0FYW9 B4ZY91 B9VGZ4 C4P7J2 C5HV42 C7S302 E1BQG4 E1BW98 E1C1U6 E1C4B7 E1C795 F1NDL3 F1NJD3 F1NJL4 F1NLV4 F1NQE8 F1NS14 F1NUQ9 G9BWP6 O13076 O57340 P15743 P17251 P48143 P68259 Q1KNA7 Q309X7 Q56IA1 Q58FG9 Q5ZJ03 Q703P0 Q802G0 Q8QGF8 Q90743 R4GFT9 R4GKD1	ADCYAP1 ADCYAP1R1 ADORA2B ADRB2 ADRB3 CALCA CALCRL CGA CRH CRHR1 EP4 FSH beta FSHB FSHb GCG GHRH GHRHR GLP-1R GLP2R GNAS GNASXL GNB1 GNB3 GNB4 GNG10 GNG12 GNG13 GNG2 GNG5 GNGT2 GPR27 GPR39 GRK5 HRH2 HTR4 HTR7 IAPP LOC107051813 MC1R MC4R MC5R Mc1r NPSR1 PACAP PDE4D PDE7B PTGER2 PTGER4 PTH PTH1R PTH2R PTHLH RAMP2 RAMP3 TSHB VIP VPAC2	Gallus gallus (chicken)
Transcriptional and post-translational regulation of MITF-M expression and activity	Adenosine 5'-monophosphoramidase HINT1 Aminoacyl tRNA synthetase complex interacting multifunctional protein 1 Aspartate--tRNA ligase, cytoplasmic Exportin 1 Glutamyl-prolyl-tRNA synthetase Kit ligand Mast/stem cell growth factor receptor Kit Protein Wnt-3a Ribosomal protein S6 kinase 2 alpha Transcription factor SOX-10	A0A1D5P8H7 A0A3Q2TSP8 F1NLE7 P18652 Q08156 Q09108 Q2LMP1 Q5ZJQ6 Q9I882 Q9W757	AIMP1 DARS EPRS KIT KITLG RPS6KA RSK SCF SOX10 WNT3A XPO1 chPKCI	Gallus gallus (chicken)
Progressive trimming of alpha-1,2-linked mannose residues from Man9/8/7GlcNAc2 to produce Man5GlcNAc2	alpha-1,2-Mannosidase	F1P0Z9	MAN1C1	Gallus gallus (chicken)	G70323CJ
Antimicrobial peptides	Angiogenin Cathelicidin B1 Cathelicidin-1 Cathelicidin-2 Cathelicidin-3 Chromogranin-A Liver ribonuclease A Lysozyme C NK-lysin Ribonuclease homolog	F1NLZ2 P00698 P27043 P30374 Q2I811 Q2IAL6 Q2IAL7 Q5GAL6 Q6QLQ5 R4GJF1	ANG CATH CATHB1 CATHL1 CATHL2 CATHL3 CHGA CL2 CMAP27 GNLY LYZ	Gallus gallus (chicken)	G49108TO
Miscellaneous transport and binding events	ANKH inorganic pyrophosphate transport regulator Leucine rich repeat containing 8 VRAC subunit A Leucine rich repeat containing 8 VRAC subunit B Leucine rich repeat containing 8 VRAC subunit C Leucine rich repeat containing 8 VRAC subunit D Lysosomal amino acid transporter 1 homolog NIPA like domain containing 3 Non imprinted in Prader-Willi/Angelman syndrome 2	A0A3Q2TZ76 E1BQK4 E1BR96 E1BYZ5 E1BZK2 E1C957 F1NBX2 Q5ZJX0	ANKH LOC107056693 LRRC8A LRRC8C LRRC8D NIPA2 NIPAL3 PQLC2 SLC66A1	Gallus gallus (chicken)
Post-translational modification: synthesis of GPI-anchored proteins	ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase Alkaline phosphatase Carboxypeptidase M Contactin-5 LY6/PLAUR domain containing 1 LY6/PLAUR domain containing 6B Limbic system-associated membrane protein MHC BF1 class I MHC class I alpha chain 2 Major prion protein homolog Neuritin 1 Opioid binding protein/cell adhesion molecule like Reticulon 4 receptor Reversion-inducing cysteine-rich protein with Kazal motifs Shadow of prion protein Tectorin beta Thy-1 membrane glycoprotein Uncharacterized protein Uncharacterized protein Uncharacterized protein	A0A1D5PBH3 A0A1D5PUP4 A0A1D5PYZ2 A0A1L1RJC1 A0A3Q2TUP5 A0A3Q3AUX4 A0ZXL5 A2BDG0 E1C041 E1C6J9 E5G6H7 F1NN44 F1NR18 F1NRZ3 F1NUK2 P27177 Q90W79 Q95601 Q98919 R4GHW2	ALPL B-FIV BF1 BF2 BFIV21 BST1 CNTN5 CPM FAR2 LOC101747868 LY6CLEL LYPD1 LYPD6B NRN1 NRN1L OPCML PRN-P PRNP RECK RTN4R SPRN TECTB THY1	Gallus gallus (chicken)
Glycosphingolipid catabolism	Acid ceramidase Beta-hexosaminidase Mannose-6-phosphate receptor, cation dependent Sulfatase N-terminal domain-containing protein exo-alpha-sialidase sphingomyelin phosphodiesterase	A0A1D5PL80 A0A1L1RMY8 A0A3Q2TVY6 E1BYN0 F1NTQ2 R4GH41	ASAH1 HEXB LOC418658 M6PR NEU2 SMPD2	Gallus gallus (chicken)	G09546QO G27025MB G58161NS
Transport of bile salts and organic acids, metal ions and amine compounds	Choline transporter-like protein Solute carrier family 5 member 7	A0A3Q3AVJ7 F1P4Q0	SLC44A5 SLC5A7	Gallus gallus (chicken)
Phospholipase C-mediated cascade; FGFR2	Fibroblast growth factor 10 Fibroblast growth factor 1 Fibroblast growth factor 2 Fibroblast growth factor 3 Fibroblast growth factor receptor 2 Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor	A0A3Q2TTH8 E1BZW7 F1P5Y5 P18461 P19596 P48800 P48801 Q197G3 Q4R0X9 Q5KRA4 Q9I950 R4GIR0	CEK3 FGF-18 FGF-3 FGF1 FGF10 FGF18 FGF2 FGF23 FGF3 FGF4 FGF6 FGF7 FGF8 FGFR2 Fgf16 Fgf7	Gallus gallus (chicken)
Reactions specific to the complex N-glycan synthesis pathway				Gallus gallus (chicken)	G70323CJ G82576YO
Signaling by BMP	Activin receptor type-2A Bone morphotic protein 10 Cerberus Dorsalin-1 Gremlin 2, DAN family BMP antagonist Mothers against decapentaplegic homolog 5 Mothers against decapentaplegic homolog Mothers against decapentaplegic homolog Mothers against decapentaplegic homolog Transforming growth factor beta receptor 3 receptor protein serine/threonine kinase receptor protein serine/threonine kinase receptor protein serine/threonine kinase	A0A1D5PB14 A0A1D5PNY8 A0A3Q3AYA9 F1NTD3 F1P3H0 F6S3W4 O42124 P34822 Q56I99 Q56IA0 Q90669 Q90998 Q9PWB0	ACVR2A BMP10 BMPR1A BMPR1B BRK-3 CER1 DSL1 GREM2 MADH5 SMAD1 SMAD5 SMAD6 SMAD7 TGFBR3	Gallus gallus (chicken)
Cellular hexose transport	Solute carrier family 2 member 11 Solute carrier family 2 member 5 Solute carrier family 2 member 8 Solute carrier family 2, facilitated glucose transporter member 12 Solute carrier family 2, facilitated glucose transporter member 3	E1C4E5 F1NDA6 F1NTJ1 F1NVV4 F1P4J7	SLC2A11 SLC2A12 SLC2A14 SLC2A5 SLC2A8	Gallus gallus (chicken)	G58161NS G70323CJ
Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors	DEK proto-onco	Q5F422	DEK	Gallus gallus (chicken)
NF-kB is activated and signals survival	Nuclear factor NF-kappa-B p105 subunit Polyubiquitin-B Sequestosome 1 TNF receptor-associated factor Tumor necrosis factor receptor superfamily member 16 Ubiquitin B Ubiquitin-ribosomal protein eS31 fusion protein	A0A1D5P546 A0A1D5PLN4 E1C626 P0CG62 P18519 P79781 Q04861	NFKB1 NGFR RPS27A SQSTM1 TNFRSF16 TRAF6 UBA80 UBB	Gallus gallus (chicken)
Estrogen-dependent gene expression	Core-binding factor beta subunit DNA-directed RNA polymerase II subunit E DNA-directed RNA polymerase subunit beta DNA-directed RNA polymerases I, II, and III subunit RPABC2 DNA-directed RNA polymerases I, II, and III subunit RPABC5 Forkhead box A1 GATA-binding factor 3 General transcription facter IIA subunit 1 variant 1 Histone H2A-IV Histone H2A.J Histone H2A.V Histone H2A Histone H2A Histone H2A Histone H2B 1/2/3/4/6 Histone H2B 5 Histone H2B 7 Histone H2B 8 Histone H2B Histone H2B Histone H3.2 Histone H3.3 Histone H4 Histone deacetylase 1 Nuclear receptor coactivator Nuclear receptor interacting protein 1 Nuclear receptor subfamily 5 group A member 2 Probable ATP-dependent RNA helicase DDX5 Protein c-Fos RNA polymerase II subunit C Runt-related transcription factor TATA-box-binding protein TLE family member 3, transcriptional corepressor Transcription initiation factor IIA subunit 2 YY2 transcription factor [histone H3]-trimethyl-L-lysine(9) demethylase peptidylprolyl isomerase	A0A1D5PCB1 A0A1D5PUH1 A0A1D5PY49 A0A1L1RNY8 A0A3Q2TSH5 A0A3Q2TTQ9 A0A3Q2U9P1 A0A3Q2UDI2 A0A3S5ZPN3 A1IIE5 A1IIE6 E1BSY6 E1BV97 F1NCB0 F1NDB6 F1NDD7 F1NHV6 F1NHV9 F1NQP4 F1P5G5 P02263 P02272 P0C1H3 P0C1H4 P0C1H5 P11939 P23825 P56517 P62801 P70082 P84229 P84247 Q5F393 Q6JLB1 Q9PSW9 Q9PT88 R4GIS3	CBFB DDX5 FKBP4 FOS FOXA1 GATA3 GTF2A1 GTF2A2 H2A-IX H2AF H2AFX H2AZ2 H2B-I H2B-II H2B-III H2B-IV H2B-V H2B-VI H2B-VII H2B-VIII H3-I H3-II H3-III H3-IV H3-IX H3-V H3-VI H3-VII H3-VIII H3-X H4-I H4-II H4-III H4-IV H4-V H4-VI H4-VII HDAC1 HDAC1A HIST1H2B5L KDM4B LOC100859381 LOC426037 NCOA1 NR5A2 NRIP1 POLR2B POLR2C POLR2E POLR2L RPB6 RUNX1 TBP TLE3 YY2	Gallus gallus (chicken)
FGFR1c ligand binding and activation	Fibroblast growth factor 1 Fibroblast growth factor 2 Fibroblast growth factor receptor 1 Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Transforming growth factor beta receptor 3	E1BZW7 F1P5Y5 P19596 P21804 P48800 Q4R0X9 Q90998 R4GIR0	CEK1 FGF1 FGF2 FGF23 FGF4 FGF6 FGF8 FGFR1 TGFBR3	Gallus gallus (chicken)
Syndecan interactions	Fibroblast growth factor 2 Integrin beta Protein kinase C Syndecan-4 Syndecan Syndecan Transforming growth factor beta	F1NV24 H9CX01 P48800 P49416 Q8JIY0 Q92071 R4GHL2	FGF2 ITGB3 PRKCA SDC1 SDC2 SDC4 TGFB1	Gallus gallus (chicken)
Proton-coupled monocarboxylate transport	Monocarboxylate transporter 1 Monocarboxylate transporter 2	F1NVU4 Q5ZLZ6	RCJMB04_4e8 SLC16A7	Gallus gallus (chicken)
Removal of aminoterminal propeptides from gamma-carboxylated proteins	Coagulation factor X Osteocalcin furin	A0A1D5PRL0 P25155 Q91000	BGLAP F10 FURIN FX	Gallus gallus (chicken)
IFNG signaling activates MAPKs	Interferon gamma receptor 2 (interferon gamma transducer 1) Interferon gamma RAF proto-oncogene serine/threonine-protein kinase Tyrosine-protein kinase	A0A1D5PS87 F1NMJ9 P05625 P49708	IFNG IFNGR2 JAK1 MIL RAF1	Gallus gallus (chicken)
Molecules associated with elastic fibres	Bone morphogenetic protein 4 Bone morphotic protein 10 Growth differentiation factor 5 Integrin beta Transforming growth factor beta Transforming growth factor beta	A0A1D5PGR5 E1C0T2 F1NNP2 F6S3W4 H9CX01 Q92071	BMP10 BMP4 GDF5 ITGB3 TGFB1 TGFB2	Gallus gallus (chicken)
Processing of DNA double-strand break ends	BRISC and BRCA1-A complex member 2 Checkpoint protein Cyclin-A1 Cyclin-A2 Cyclin-dependent kinase 2 DNA replication ATP-dependent helicase/nuclease DNA2 DNA topoisomerase II binding protein 1 Fanconi anemia group J protein homolog Histone H2A Histone H2A Histone H2A Histone H2B 1/2/3/4/6 Histone H2B 5 Histone H2B 7 Histone H2B 8 Histone H2B Histone H2B Histone H4 Protein inhibitor of activated STAT 4 RAD1 checkpoint DNA exonuclease Rad9 RecQ-mediated genome instability protein 2 Replication factor A protein 2 Replication factor C subunit 2 Replication factor C subunit 3 Replication factor C subunit 4 Replication protein A 14 kDa subunit Replication protein A 70 kDa DNA-binding subunit SUMO-conjugating enzyme UBC9 Serine/threonine-protein phosphatase 4 regulatory subunit 2 Small ubiquitin-related modifier 2	A0A1D5P2D1 A0A1D5P3M9 A0A1D5PSK5 A0A1D5PTJ5 A0A1D5PY49 A0A1L1RNY8 A0A1L1RUB9 A0A3Q2UDI2 A2IAR9 E1C4C7 F1NDD7 F1NJI2 F1P3C0 F1P4N0 F1P5G5 P0C1H3 P0C1H4 P0C1H5 P53033 P62801 P63283 Q3YK19 Q5ZJJ2 Q5ZJM9 Q5ZKG3 Q5ZLH1 Q5ZM20 Q5ZML0 Q5ZMU6 Q76F79 Q9PSW9	BABAM2 BRE BRIP1 CCNA1 CCNA2 CDK2 DNA2 DNA2L FANCJ H2AFX H2B-I H2B-II H2B-III H2B-IV H2B-V H2B-VI H2B-VII H2B-VIII H4-I H4-II H4-III H4-IV H4-V H4-VI H4-VII HIST1H2B5L HUS1 LOC100859381 LOC426037 PIAS4 PPP4R2 RAD1 RAD9A RCJMB04_6d17 RFC2 RFC3 RFC4 RMI2 RPA1 RPA3 SUMO2 TOPBP1 UBC9 UBCE9 UBE2I rad9	Gallus gallus (chicken)
Interferon gamma signaling	Interferon gamma receptor 2 (interferon gamma transducer 1) Interferon gamma Protein kinase C delta type Signal transducer and activator of transcription Suppressor of cytokine signaling 1 Suppressor of cytokine signaling 3 Tyrosine-protein kinase calcium/calmodulin-dependent protein kinase	A0A1D5PS87 B6RCQ2 F1NGS8 F1NMJ9 F1P3G1 P49708 Q5ZJK3 R4GJH9	CAMK2A IFNG IFNGR2 JAK1 PRKCD RCJMB04_17i9 SOCS1 SOCS3	Gallus gallus (chicken)
Initial triggering of complement	Collectin-10 Collectin-11 Complement C1q B chain Complement C1q C chain Mannose-binding protein Uncharacterized protein complement subcomponent C1r	A0A1D5PGB2 A0A1D5PIR0 A0A3Q3A736 F1NAB7 F1NH19 Q2LK95 Q98TA4	C1QB C1QC C1R CL1 COLEC10 COLEC11 MBL	Gallus gallus (chicken)	G49108TO G57321FI
Hormone ligand-binding receptors	Follitropin subunit beta Glycoprotein hormones alpha chain Progonadoliberin-1 Thyrotropin subunit beta Type 1/III gonadotropin-releasing hormone receptor hexahelical variant	B5G4W1 F1NJD3 O57340 P37042 Q8QGF8	CGA FSH beta FSHB FSHb GNRH1 GNRHR1/III TSHB	Gallus gallus (chicken)

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