GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	November 12, 2024
ECODAB	April 1, 2019

Displaying entries **1 - 25** of **270** in total

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Pathway Name	Protein Name	UniProt ID ▲	Gene Symbol	Organism	GlyTouCan ID
N-glycan trimming and elongation in the cis-Golgi				Gallus gallus (chicken)	G58161NS
Reactions specific to the complex N-glycan synthesis pathway				Gallus gallus (chicken)	G70323CJ G82576YO
Digestion of dietary carbohydrate				Gallus gallus (chicken)	G58161NS G74621DY G93924TT G96370VA
Lysosomal oligosaccharide catabolism				Gallus gallus (chicken)	G00027MO G25577BM G28233ME G70323CJ G90333CG
Ficolins bind to repetitive carbohydrate structures on the target cell surface				Gallus gallus (chicken)	G49108TO G57321FI
Elastic fibre formation	Integrin beta Lysyl oxidase homolog furin	A0A0A0MQ32 Q91000 Q92071	FURIN ITGB3 LOXL2	Gallus gallus (chicken)
G alpha (i) signalling events	5-hydroxytryptamine receptor 1B 5-hydroxytryptamine receptor 1D 5-hydroxytryptamine receptor 1E 5-hydroxytryptamine receptor 1F Adenosine receptor A1 Adrenoceptor alpha 2C Alpha-2A adrenergic receptor Apelin receptor Apelin B1 bradykinin receptor C-C chemokine receptor 7 C-C motif chemokine 4 homolog C-C motif chemokine ligand 19 C-C motif chemokine receptor 8 C-C motif chemokine C-C motif chemokine C-C motif chemokine C-X-C chemokine receptor type 2 C-X-C motif chemokine ligand 13 C-X-C motif chemokine receptor 4 C-X-C motif chemokine C-X3-C motif chemokine ligand 1 C-X3-C motif chemokine receptor 1 Chemerin-like receptor 2 Chemokine K203 Chemokine receptor Chemokine receptor Chemokine Chemokine Chemokine Chemokine Chemokine D(3) dopamine receptor DRD4 G protein subunit alpha transducin 2 G protein subunit alpha transducin 3 G protein subunit beta 3 G protein subunit beta 4 G protein subunit gamma 13 G protein-coupled receptor 37 like 1 G protein-coupled receptor 55 G-protein coupled estrogen receptor 1 G-protein coupled receptors family 1 profile domain-containing protein G-protein-signaling modulator 2 Galanin peptides Galanin receptor Gamma-aminobutyric acid type B receptor subunit 2 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 Guanine nucleotide-binding protein G(i) subunit alpha-1 Guanine nucleotide-binding protein G(i) subunit alpha-2 Guanine nucleotide-binding protein G(i) subunit alpha-3 Guanine nucleotide-binding protein subunit gamma Guanine nucleotide-binding protein subunit gamma Guanine nucleotide-binding protein subunit gamma Guanine nucleotide-binding protein subunit gamma Guanine nucleotide-binding protein subunit gamma Interleukin-8 Kappa-type opioid receptor Lymphotactin Lysophosphatidic acid receptor 1 Lysophosphatidic acid receptor 3 Melatonin receptor 1B Melatonin receptor type 1A Metabotropic glutamate receptor 3 Mu-type opioid receptor Muscarinic acetylcholine receptor M2 N-arachidonyl glycine receptor Neuromedin U receptor 2 Neuromedin U receptor type 1 Neuromedin U Neuromedin-S Neuropeptide W Neuropeptide Y receptor 4 Neuropeptide Y receptor type 1 Neuropeptide Y receptor type 2 Neuropeptide Y receptor type 5 Neuropeptides B and W receptor 1 Nociceptin receptor Opsin 3 Opsin 5 PMCH Pancreatic polypeptide Peptide YY Prepronociceptin isoform X1 variant X1 Pro-neuropeptide Y Proenkephalin Prostaglandin E2 receptor EP3 subtype Proto-oncogene tyrosine-protein kinase Src Regulator of G protein signaling 7 Regulator of G-protein signaling 17 Regulator of G-protein signaling 18 Regulator of G-protein signaling 20 Regulator of G-protein signaling 4 Regulator of G-protein signaling 5 Regulator of G-protein signaling 8 Retinal G protein coupled receptor Retinal pigment epithelium-derived rhodopsin homolog Rhodopsin Somatostatin II Somatostatin receptor 1 Somatostatin receptor 4 Somatostatin receptor 5 Somatostatin receptor type 2 Somatostatin receptor type 3 Somatostatin Sphingosine-1-phosphate receptor 2 Succinate receptor 1 Taste receptor type 2 member 40 Taste receptor type 2 Taste receptor type 2 Urotensin-2 receptor	A0A0A0MQ60 A0A0S3UPI6 A0A172PWX7 A0A1D5P1L7 A0A1D5P622 A0A1D5P7Z5 A0A1D5PLZ8 A0A1D5PT23 A0A1D5PXC7 A0A1D5PXM6 A0A1D5PZ45 A0A1L1RZN8 A0A1L7HA09 A0A2I6J485 A0A3Q2U125 A0A3Q2U480 A0A3Q2UHB6 A0A3S5ZP53 A0A3S5ZPM8 A0A3S5ZPQ6 A0MAR6 A9UGZ3 B0FMV4 B0FMV6 B2BJC3 B2ZE94 B6UVA0 C3V8R3 C5HV40 D3Y1H8 E1BR28 E1BRK8 E1BS44 E1BUE5 E1BW98 E1BWP2 E1BX29 E1BXS2 E1BYD3 E1BYR3 E1BZQ1 E1C0V9 E1C1F4 E1C1U6 E1C327 E1C3Z3 E1C5A6 E1C652 E1C733 E1C795 E1C7I3 E1C968 E3VW39 F1NA96 F1NDD8 F1NEH2 F1NEL9 F1NEY2 F1NHZ4 F1NJ18 F1NLV4 F1NQY7 F1NRF0 F1NW54 F1NWC2 F1NWY5 F1NYB0 F1P147 F1P148 F1P166 F1P167 F1P193 F1P3R0 F1P3Y2 F6RCI2 G4U4M4 O57411 O73912 P00523 P08317 P28673 P30372 P33094 P49285 P49892 P50147 P68248 Q1KMR2 Q2AB81 Q2AB83 Q334G8 Q38Q38 Q4KS30 Q4ZJF2 Q58G84 Q5IEZ5 Q5ZJ03 Q8QFM1 Q8QG55 Q8QGM3 Q90826 Q90847 Q9DDN6 Q9PWA0 Q9PWA1 R4GF58 R4GFT9 R4GJB7 R4GKD1 R4GKX0 R4GM50	ADORA1 ADRA2A ADRA2C APLN APLNR APLNR1 BDKRB1 CCL19 CCL20 CCL26 CCL4 CCLL4 CCLi10 CCLi6 CCLi7 CCLi8 CCLi9 CCR5 CCR7 CCR8 CCRa CEF4 CHRM2 CM2 CX3CL1 CX3CR1 CXCL13 CXCL8 CXCR1 CXCR4 CXCR5 DRD3 DRD4 EMF1 EP3 GABBR2 GAL GALR GNAI1 GNAI2 GNAI3 GNAT2 GNAT3 GNB1 GNB3 GNB4 GNG10 GNG12 GNG13 GNG2 GNG5 GNGT2 GPER1 GPR1 GPR18 GPR37L1 GPR55 GPSM2 GRM3 Galphai3 HTR1B HTR1D HTR1E HTR1F IL8 LOC100857191 LOC101747503 LOC428525 LPAR1 LPAR3 MIP-3alpha MTNR1B NMS NMU NMUR1 NMUR2 NPBWR1 NPW NPY NPY1R NPY2R NPY4R NPY5R OPN3 OPN5 OPRK1 OPRL1 OPRM1 PENK PMCH PNOC PPY PTGER3 PYY RGR RGS17 RGS18 RGS20 RGS4 RGS5 RGS7 RGS8 RHO RRH S1PR2 SCYA4 SRC SS1R SS2 SS2R SS3R SST SSTR1 SSTR2 SSTR4 SSTR5 SUCNR1 TAS2R1 TAS2R40 TAS2R7 UTS2R XCL1 cOpn3m k60 scyc1	Gallus gallus (chicken)
Class A/1 (Rhodopsin-like receptors)	Chemerin-like receptor 1 G protein-coupled receptor 55 G protein-coupled receptor 65 G-protein coupled receptor 39 G-protein coupled receptors family 1 profile domain-containing protein Melatonin receptor 1B Melatonin receptor type 1A N-arachidonyl glycine receptor Platelet-activating factor receptor Succinate receptor 1	A0A0A0MQ60 A0A1D5P7P2 A0A3Q2U480 A1XWZ9 E1C095 F1NA96 F1NJ83 F1NRF0 P49285 R4GHJ0	CMKLR1 GPR132 GPR18 GPR39 GPR55 GPR65 MTNR1B PTAFR SUCNR1	Gallus gallus (chicken)
RET signaling	Docking protein 1 Fibroblast growth factor receptor substrate 2 GDNF family receptor alpha-1 Growth factor receptor bound protein 10 Growth factor receptor-bound protein 2 PDZ and LIM domain protein 7 Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphoinositide-3-kinase regulatory subunit 2 Protein kinase C Proto-oncogene tyrosine-protein kinase Src SHC-transforming protein 1 SOS Ras/Rac guanine nucleotide exchange factor 1 Tyrosine-protein phosphatase non-receptor type 11 phosphatidylinositol-4,5-bisphosphate 3-kinase phosphatidylinositol-4,5-bisphosphate 3-kinase	A0A0E4BA89 A0A1D5NYP8 A0A1D5P405 A0A1D5PEZ2 A0A1D5PZ39 A0A3Q3ACS4 A3R0S3 E1C021 E1C2C5 F1NHX1 O13156 P00523 Q5F4A2 Q90687 R4GHL2	DOK1 FRS2 GDNFRA GFRA1 GRB10 GRB2 PDLIM7 PIK3CB PIK3CD PIK3R1 PIK3R2 PRKCA PTPN11 SHC1 SOS1 SRC	Gallus gallus (chicken)
Platelet degranulation	ATP binding cassette subfamily C member 4 Actin, cytoplasmic 2 Albumin Alpha-1-acid glycoprotein Alpha-actinin-1 Alpha-actinin-2 Amyloid beta like protein 2 Annexin A5 Apolipoprotein A-I C-type lectin domain family 3 member B CYFIP related Rac1 interactor B Coagulation factor XIII A chain Fibronectin GTP binding protein 2 Hsp90 co-chaperone Cdc37-like 1 Insulin-like growth factor I Insulin-like growth factor II Integrin beta Intracellular hyaluronan-binding protein 4 LHFPL tetraspan subfamily member 2 MAGE protein Metalloproteinase inhibitor 3 Obg-like ATPase 1 Plasminogen Platelet-derived growth factor subunit A Protein FAM3C Retinoic acid receptor responder protein 2 Saccharopine dehydrogenase-like oxidoreductase Sulfhydryl oxidase 1 Tetraspanin Torsin family 4 member A Transforming growth factor beta Transforming growth factor beta Vascular endothelial growth factor D Vesicle transport through interaction with t-SNAREs 1B Vinculin	A0A0K0PUH6 A0A165EAY6 A0A1D5NW68 A0A1D5PSS5 A0A1D5PZ00 E1BUX5 E1BVB5 E1BWA9 E1BWG1 F1NAG8 F1NH83 F1NLT2 F1NNP2 F1NWX6 F1P0A7 H9CX01 P05094 P08250 P11722 P12003 P17153 P18254 P20111 P26652 P33717 Q001T8 Q5ZM25 Q5ZMK3 Q5ZMQ2 Q8JGM4 Q8JIG5 Q90WK2 Q92071 Q9DDD4 Q9I9R0 Q9IBC9	ABCC4 ACTG1 ACTN1 ACTN2 ALB ANX5 ANXA5 APLP2 APOA1 CD9 CDC37L1 CLEC3B F13A1 FAM3C FAM49B FN1 GTPBP2 HABP4 IGF1 IGF2 IMP-3 ITGB3 LHFPL2 OGCHI OLA1 ORM1 PDGF-A (L) PDGFA PLG QSCN6 QSOX QSOX1 RARRES2 RCJMB04_1m12 SOX TGFB1 TGFB2 TIMP3 TOR4A VCL VEGFD VINC1 VTI1B mage ogchi	Gallus gallus (chicken)
Peptide ligand-binding receptors	Apelin receptor Apelin B1 bradykinin receptor Bombesin receptor subtype-3 Cholecystokinin receptor type A Coagulation factor II thrombin receptor like 2 Endothelin-1 receptor Endothelin-2 Endothelin-converting enzyme 1 F2R like trypsin receptor 1 G protein-coupled receptor 37 like 1 G-protein coupled estrogen receptor 1 Galanin peptides Galanin receptor Gastrin-releasing peptide Kappa-type opioid receptor Melanocortin receptor 4 Melanocortin receptor 5 Melanocyte-stimulating hormone receptor Motilin receptor Mu-type opioid receptor Neuromedin B Neuromedin U receptor 2 Neuromedin U receptor type 1 Neuromedin U Neuromedin-B receptor Neuromedin-S Neuropeptide S receptor Neuropeptide S Neuropeptide W Neuropeptide Y receptor 4 Neuropeptide Y receptor type 1 Neuropeptide Y receptor type 2 Neuropeptide Y receptor type 5 Neuropeptides B and W receptor 1 Neurotensin receptor 1 Nociceptin receptor PMCH Pancreatic polypeptide Peptide YY Prepronociceptin isoform X1 variant X1 Preprourotensin II Pro-neuropeptide Y Pro-thyrotropin-releasing hormone Proenkephalin Prokineticin 2 Somatostatin II Somatostatin receptor 1 Somatostatin receptor 4 Somatostatin receptor 5 Somatostatin receptor type 2 Somatostatin receptor type 3 Somatostatin Thyrotropin-releasing hormone receptor Type-1 angiotensin II receptor Urotensin-2 receptor XK-related protein	A0A0S3UPI6 A0A172PWX7 A0A1D5P3F4 A0A1D5P8Y9 A0A1D5PAZ6 A0A1D5PKZ0 A0A1L7HA09 A0A2I6J485 A0A3Q2U9J5 A0A3S5ZP53 A0MAR6 A0ZPS0 A9UGZ3 B2KSC0 B2ZE94 C3V8R3 E1BRK8 E1BRP1 E1BWP2 E1BX29 E1BYD3 E1BYR3 E1C0V9 E1C327 E1C482 E1C652 E1C968 E7FKE5 F1NEH2 F1NJ18 F1NP50 F1NQE8 F1NTV9 F1NW54 F1NWC2 F1NWY5 F1P2V3 F6RCI2 O73739 P01295 P28673 P33094 P68248 P79785 Q38Q38 Q4ZJF2 Q58G84 Q5F4D0 Q6Q2J6 Q6ZXC3 Q802E6 Q802G0 Q8QFM1 Q8QGM3 Q9DDN6 Q9DGN6 R4GF58	AGTR1 APLN APLNR APLNR1 BDKRB1 BRS3.5 CCK1R CCKAR ECE-1 EDN2 EDNRA F2RL1 F2RL2 GAL GALR GPER1 GPR37L1 GRP MC1R MC4R MC5R MLNR Mc1r NMB NMBR NMS NMU NMUR1 NMUR2 NPBWR1 NPSR1 NPW NPY NPY1R NPY2R NPY4R NPY5R NTSR1 OPRK1 OPRL1 OPRM1 PENK PMCH PNOC PPY PROK2 PYY SS1R SS2 SS2R SS3R SST SSTR1 SSTR2 SSTR4 SSTR5 TRH TRHR UTS2 UTS2R XK	Gallus gallus (chicken)
Ub-specific processing proteases	26S proteasome non-ATPase regulatory subunit 13 26S proteasome non-ATPase regulatory subunit 2 26S proteasome regulatory subunit 7 AAA+ ATPase domain-containing protein Adhesion regulating molecule 1 Androgen receptor Axin 2 Axin-1 Beta-2 adrenergic receptor Cell division cycle 20 Cyclin-A1 Cyclin-A2 DNA damage-binding protein 2 E3 ubiquitin-protein ligase Mdm2 E3 ubiquitin-protein ligase Histone H2A-IV Histone H2A.J Histone H2A Histone H2B 1/2/3/4/6 Histone H2B 5 Histone H2B 7 Histone H2B 8 Histone H2B Histone H2B Mothers against decapentaplegic homolog 3 Mothers against decapentaplegic homolog Mothers against decapentaplegic homolog Mothers against decapentaplegic homolog Mothers against decapentaplegic homolog Myc proto-oncogene protein Polyubiquitin-B Proteasome 26S subunit, non-ATPase 12 Proteasome 26S subunit, non-ATPase 14 Proteasome 26S subunit, non-ATPase 7 Proteasome subunit alpha type Proteasome subunit alpha type Proteasome subunit alpha type Proteasome subunit alpha type Proteasome subunit alpha type Proteasome subunit beta Proteasome subunit beta Proteasome subunit beta RuvB-like helicase S-phase kinase associated protein 2 Sorting nexin 3 TGF-beta receptor type-1 TNF receptor-associated factor Translocase of outer mitochondrial membrane 20 Translocase of outer mitochondrial membrane 70 Ubiquitin B Ubiquitin carboxyl-terminal hydrolase Ubiquitin carboxyl-terminal hydrolase Ubiquitin fusion-degradation 1-like protein Ubiquitin-ribosomal protein eS31 fusion protein WD repeat domain 20 WD repeat-containing protein 48 peptidyl-tRNA hydrolase ubiquitinyl hydrolase 1 ubiquitinyl hydrolase 1	A0A1D5NTD3 A0A1D5NUH3 A0A1D5P088 A0A1D5P395 A0A1D5P546 A0A1D5P7A9 A0A1D5P9H5 A0A1D5PJW4 A0A1D5PK45 A0A1D5PKT3 A0A1D5PNY8 A0A1D5PPH8 A0A1D5PY49 A0A1L1RNY8 A0A3Q2TX44 A0A3Q2UDI2 A0A3Q3A989 E1BWS4 E1BX02 E1C3Q9 E1C626 E1C6N0 F1N8Z4 F1NC02 F1NEQ6 F1NGX6 F1NJI2 F1NNH9 F1NPQ0 F1NR71 F1P4C5 F1P4N0 F7BEK8 P01109 P02263 P0C1H3 P0C1H4 P0C1H5 P0CG62 P70082 P79781 P84023 P84169 Q06900 Q56IA0 Q5F3K4 Q5ZI36 Q5ZIA3 Q5ZIT7 Q5ZJL7 Q5ZJX9 Q5ZLI2 Q5ZMB8 Q6JLB2 Q7ZT63 Q8UWF3 Q98UC3 Q9PSW9 R4GLB3	ADRB2 ADRM1 AR AXIN1 AXIN2 CCNA1 CCNA2 CDC20 ChALK5 DDB2 H2A-IX H2AFX H2B-I H2B-II H2B-III H2B-IV H2B-V H2B-VI H2B-VII H2B-VIII HIST1H2B5L LOC426037 LOC769000 MADH2 MADH3 MDM2 MYC PSMA3 PSMA4 PSMA6 PSMA7 PSMB1 PSMB2 PSMB7 PSMC2 PSMD12 PSMD13 PSMD14 PSMD2 PSMD7 PTRH2 RCJMB04_14i9 RCJMB04_23k2 RPS27A RUVBL1 SIAH2 SKP2 SMAD1 SMAD3 SMAD7 SNX3 TGFBR1 TOMM20 TOMM70 TRAF6 UAF1 UBA80 UBB USP12 USP15 USP34 USP44 Ufd1l WDR20 WDR48 cpsmb7	Gallus gallus (chicken)
Assembly of the pre-replicative complex	26S proteasome non-ATPase regulatory subunit 13 26S proteasome non-ATPase regulatory subunit 2 26S proteasome regulatory subunit 7 AAA+ ATPase domain-containing protein Adhesion regulating molecule 1 Anaphase-promoting complex subunit CDC26 Cell division cycle protein 27 homolog DNA replication licensing factor MCM3 DNA replication licensing factor MCM4 DNA replication licensing factor MCM5 DNA replication licensing factor MCM6 Fizzy/cell division cycle 20 related 1 Polyubiquitin-B Proteasome 26S subunit, non-ATPase 12 Proteasome 26S subunit, non-ATPase 14 Proteasome 26S subunit, non-ATPase 7 Proteasome subunit alpha type Proteasome subunit alpha type Proteasome subunit alpha type Proteasome subunit alpha type Proteasome subunit alpha type Proteasome subunit beta Proteasome subunit beta Proteasome subunit beta Ubiquitin B Ubiquitin-conjugating enzyme E2 C Ubiquitin-ribosomal protein eS31 fusion protein	A0A1D5NTD3 A0A1D5P546 A0A1D5PJW4 A0A3Q2UD09 E1BX02 E1C2U4 E1C6N0 F1NC02 F1NEQ6 F1NFJ0 F1NPQ0 F1NR71 H9L1Y1 P0CG62 P79781 P84169 Q5ZIT7 Q5ZJX9 Q5ZK91 Q5ZKL0 Q5ZKR8 Q5ZLI2 Q5ZMB8 Q6JLB2 Q7ZT63 R4GJY8 R4GLB3	ADRM1 CDC26 FZR1 MCM3 MCM4 MCM5 PSMA3 PSMA4 PSMA6 PSMA7 PSMB1 PSMB2 PSMB7 PSMC2 PSMD12 PSMD13 PSMD14 PSMD2 PSMD7 RCJMB04_12e16 RCJMB04_14i9 RCJMB04_23k2 RCJMB04_9i8 RPS27A UBA80 UBB UBE2U cpsmb7	Gallus gallus (chicken)
TNFR2 non-canonical NF-kB pathway	26S proteasome non-ATPase regulatory subunit 13 26S proteasome non-ATPase regulatory subunit 2 26S proteasome regulatory subunit 7 AAA+ ATPase domain-containing protein Adhesion regulating molecule 1 B-cell-activating factor BAFF CD40 ligand Proteasome 26S subunit, non-ATPase 12 Proteasome 26S subunit, non-ATPase 14 Proteasome 26S subunit, non-ATPase 7 Proteasome subunit alpha type Proteasome subunit alpha type Proteasome subunit alpha type Proteasome subunit alpha type Proteasome subunit alpha type Proteasome subunit beta Proteasome subunit beta Proteasome subunit beta TNF receptor superfamily member 1B TNF receptor-associated factor	A0A1D5NTD3 A0A1D5PJW4 A0A1D5PTU3 A0A3Q3AAA5 E1BX02 E1C6N0 F1NC02 F1NEQ6 F1NPQ0 F1NR71 P84169 Q5ZIT7 Q5ZJX9 Q5ZLI2 Q5ZMB8 Q6JLB2 Q7ZT63 Q8JHJ4 Q9I8D8 R4GLB3	ADRM1 BAFF CD40L CD40LG PSMA3 PSMA4 PSMA6 PSMA7 PSMB1 PSMB2 PSMB7 PSMC2 PSMD12 PSMD13 PSMD14 PSMD2 PSMD7 RCJMB04_14i9 RCJMB04_23k2 TNFRSF1B TNFSF13B TNFSF5 TRAF3 cpsmb7	Gallus gallus (chicken)
WNT ligand biogenesis and trafficking	Protein Wnt-11 Protein Wnt-3a Protein Wnt-4 Protein Wnt-7b Protein Wnt Protein Wnt Protein Wnt Protein Wnt Protein Wnt Protein Wnt Protein Wnt Sorting nexin 3 Transmembrane emp24 domain-containing protein 5 Wntless Wnt ligand secretion mediator	A0A1D5NTF4 A1DYI3 F1P376 P49337 P49339 Q2LMP1 Q3C2H6 Q3L254 Q564K5 Q5ZIA3 Q5ZMT4 Q60GF6 Q9DEB8 Q9YGX6	SNX3 TMED5 WLS WNT-11 WNT-4 WNT10A WNT11 WNT2 WNT3 WNT3A WNT4 WNT5A WNT7A WNT7B Wnt10a Wnt3 Wnt6 Wnt8c	Gallus gallus (chicken)
Ca2+ pathway	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase Catenin beta-1 Frizzled class receptor 3 Frizzled-4 G protein subunit alpha transducin 2 G protein subunit beta 3 G protein subunit beta 4 G protein subunit gamma 13 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 Guanine nucleotide-binding protein G(o) subunit alpha Guanine nucleotide-binding protein subunit gamma Guanine nucleotide-binding protein subunit gamma Guanine nucleotide-binding protein subunit gamma Guanine nucleotide-binding protein subunit gamma Guanine nucleotide-binding protein subunit gamma Lymphoid enhancer binding factor 1 Phosphodiesterase Protein Wnt-11 Protein Wnt Protein phospatase 3 regulatory subunit B alpha isoform type 1 Rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma calcium/calmodulin-dependent protein kinase small monomeric GTPase	A0A1D5NTJ0 A0A1D5NYE8 A0A1D5NZL7 A0A1D5P7Z5 A0A1D5PLZ8 A0A1D5PT95 A0A1D5PZ45 A0A3Q2UEZ9 A0A3Q3B1W2 E1BW98 E1C1U6 E1C795 F1NA42 F1NGS8 F1NLV4 P49339 Q5ZJ03 Q6VN51 Q802E4 Q9IA05 Q9YGX6 R4GFT9 R4GKD1	CAMK2A CTNNB1 FZ4 FZD3 FZD4 GNAO1 GNAT2 GNB1 GNB3 GNB4 GNG10 GNG12 GNG13 GNG2 GNG5 GNGT2 KRAS LEF1 OXLD1 PDE6B PDE6b PLCB1 RCJMB04_23k16 WNT-11 WNT11 WNT5A	Gallus gallus (chicken)
PRC2 methylates histones and DNA	AE binding protein 2 DNA (cytosine-5-)-methyltransferase Histone H2A-IV Histone H2A.J Histone H2A.V Histone H2A Histone H2A Histone H2A Histone H2B 1/2/3/4/6 Histone H2B 5 Histone H2B 7 Histone H2B 8 Histone H2B Histone H2B Histone H3.2 Histone H3.3 Histone H4 Polycomb protein EED RB binding protein 4, chromatin remodeling factor	A0A1D5NTR2 A0A1D5PMP0 A0A1D5PY49 A0A1L1RNY8 A0A3Q2UDI2 F1NDD7 F1P5G5 F2Z4M0 P02263 P02272 P0C1H3 P0C1H4 P0C1H5 P62801 P70082 P84229 P84247 Q5ZKH3 Q9PSW9	AEBP2 DNMT3A Dnmt3a EED H2A-IX H2AF H2AFX H2AZ2 H2B-I H2B-II H2B-III H2B-IV H2B-V H2B-VI H2B-VII H2B-VIII H3-I H3-II H3-III H3-IV H3-IX H3-V H3-VI H3-VII H3-VIII H3-X H4-I H4-II H4-III H4-IV H4-V H4-VI H4-VII HIST1H2B5L LOC100859381 LOC426037 RBBP4	Gallus gallus (chicken)
Keratan sulfate biosynthesis	Beta-1,4-galactosyltransferase Beta-1,4-galactosyltransferase CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 1 Fibromodulin Hexosyltransferase Keratocan Lumican Mimecan Sulfotransferase	A0A1D5NTY7 A0A1D5NVT2 A0A1D5PSH8 A0A3S5ZPV4 O42235 P51890 Q11200 Q5ZK57 Q9W6H0	B3GNT2 B4GALT2 B4GALT6 CHST2 FMOD KERA LDC LUM OGN SIAT4A ST3GAL1	Gallus gallus (chicken)
Keratan sulfate degradation	Beta-hexosaminidase Fibromodulin Keratocan Lumican Mimecan N-acetylglucosamine-6-sulfatase	A0A1D5NTY7 F1NI04 F1NTQ2 O42235 P51890 Q9W6H0	FMOD GNS HEXB KERA LDC LUM OGN	Gallus gallus (chicken)	G09546QO G20239CJ G27025MB G50451AA G80016QC G82768YB G85384LV
MLL4 and MLL3 complexes regulate expression of PPARG target genes in adipogenesis and hepatic steatosis	Cyclin-C Histone H2A-IV Histone H2A.J Histone H2A.V Histone H2A Histone H2A Histone H2A Histone H2B 1/2/3/4/6 Histone H2B 5 Histone H2B 7 Histone H2B 8 Histone H2B Histone H2B Histone H3.2 Histone H3.3 Histone H4 Mediator of RNA polymerase II transcription subunit 17 Mediator of RNA polymerase II transcription subunit 1 Mediator of RNA polymerase II transcription subunit 20 Mediator of RNA polymerase II transcription subunit 30 Mediator of RNA polymerase II transcription subunit 31 Mediator of RNA polymerase II transcription subunit 4 Mediator of RNA polymerase II transcription subunit 7 Nuclear coactivator domain-containing protein Nuclear receptor coactivator RB transcriptional corepressor 1 Retinoic acid receptor RXR Transducin beta like 1 X-linked receptor 1	A0A1D5NUC6 A0A1D5NXL1 A0A1D5P2B5 A0A1D5P8W2 A0A1D5PK99 A0A1D5PY49 A0A1L1RNY8 A0A3Q2UDI2 A0A3Q3AS57 E1BUI5 E1C6N9 F1NDD7 F1NY10 F1P5G5 P02263 P02272 P0C1H3 P0C1H4 P0C1H5 P55168 P62801 P70082 P84229 P84247 Q5F393 Q5ZKY9 Q5ZMB1 Q9PSW9	CCNC H2A-IX H2AF H2AFX H2AZ2 H2B-I H2B-II H2B-III H2B-IV H2B-V H2B-VI H2B-VII H2B-VIII H3-I H3-II H3-III H3-IV H3-IX H3-V H3-VI H3-VII H3-VIII H3-X H4-I H4-II H4-III H4-IV H4-V H4-VI H4-VII HIST1H2B5L LOC100859381 LOC426037 MED1 MED17 MED20 MED30 MED31 MED4 MED7 NCOA1 RB1 RCJMB04_2k10 RXRA TBL1XR1 TRFP	Gallus gallus (chicken)
Generic Transcription Pathway	C2H2-type domain-containing protein Cyclin-C Mediator of RNA polymerase II transcription subunit 17 Mediator of RNA polymerase II transcription subunit 1 Mediator of RNA polymerase II transcription subunit 20 Mediator of RNA polymerase II transcription subunit 30 Mediator of RNA polymerase II transcription subunit 31 Mediator of RNA polymerase II transcription subunit 4 Mediator of RNA polymerase II transcription subunit 7 Zinc finger protein 704 Zinc finger protein 706	A0A1D5NUC6 A0A1D5P8W2 A0A1D5PFE9 A0A1D5PK99 A0A1L1RJ75 E1BUI5 E1C6N9 F1NY10 P55168 Q5ZKY9 Q5ZMM5	CCNC LOC101747670 MED1 MED17 MED20 MED30 MED31 MED4 MED7 TRFP ZNF704 ZNF706	Gallus gallus (chicken)
Downregulation of TGF-beta receptor signaling	BMP and activin membrane-bound inhibitor homolog E3 ubiquitin-protein ligase CHIP Mothers against decapentaplegic homolog 3 Mothers against decapentaplegic homolog Mothers against decapentaplegic homolog Mothers against decapentaplegic homolog Polyubiquitin-B Prostate transmembrane protein, androgen induced 1 Serine-threonine kinase receptor-associated protein TGF-beta receptor type-1 TGF-beta receptor type-2 Transforming growth factor beta Ubiquitin B Ubiquitin-ribosomal protein eS31 fusion protein	A0A1D5NUH3 A0A1D5P546 A0A1D5PNY8 E1AWU3 H9CX01 P0CG62 P79781 P84023 Q06900 Q5ZHY5 Q5ZJ16 Q5ZL33 Q8UWF3 Q90999	BAMBI ChALK5 LOC769000 MADH2 MADH3 PMEPA1 RPS27A SMAD3 SMAD7 STRAP STUB1 TGFB1 TGFBR1 TGFBR2 UBA80 UBB	Gallus gallus (chicken)
Downregulation of SMAD2/3:SMAD4 transcriptional activity	Mothers against decapentaplegic homolog 3 Mothers against decapentaplegic homolog Mothers against decapentaplegic homolog Polyubiquitin-B Protein ATP1B4 SKI like proto-onco Ski oncogene Ubiquitin B Ubiquitin-ribosomal protein eS31 fusion protein	A0A1D5NUH3 A0A1D5P546 E1BSJ7 F1P0N0 P0CG62 P79781 P84023 Q2HZ96 Q8UWF3	ATP1B4 LOC769000 MADH2 MADH3 RPS27A SKI SKIL SMAD3 UBA80 UBB	Gallus gallus (chicken)
Signaling by Activin	Activin receptor type-2A Inhibin beta B chain Mothers against decapentaplegic homolog 3 Mothers against decapentaplegic homolog Mothers against decapentaplegic homolog Transforming growth factor beta receptor 3 receptor protein serine/threonine kinase	A0A1D5NUH3 A0A3Q2TUT8 P84023 Q8UWF3 Q90669 Q90998 R4GIS0	ACVR1C ACVR2A INHBB LOC769000 MADH2 MADH3 SMAD3 TGFBR3	Gallus gallus (chicken)
TGF-beta receptor signaling activates SMADs	Integrin beta Mothers against decapentaplegic homolog 3 Mothers against decapentaplegic homolog Mothers against decapentaplegic homolog TGF-beta receptor type-1 TGF-beta receptor type-2 Transforming growth factor beta receptor 3 Transforming growth factor beta Transforming growth factor beta Zinc finger FYVE domain-containing protein furin peptidylprolyl isomerase	A0A1D5NUH3 E1C6T3 F1NNP2 H9CX01 P84023 Q06900 Q8UWF3 Q90998 Q90999 Q90ZG0 Q91000 Q92071	ChALK5 FKBP12 FURIN ITGB3 LOC769000 MADH2 MADH3 SMAD3 TGFB1 TGFB2 TGFBR1 TGFBR2 TGFBR3 ZFYVE9	Gallus gallus (chicken)

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