GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	March 20, 2024
ECODAB	April 1, 2019

Displaying entries **1 - 25** of **250** in total

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Pathway Name ▲	Protein Name	UniProt ID	Gene Symbol	Organism
ABC transporters in lipid homeostasis	Peroxisomal biogenesis factor 3 Peroxisomal long-chain fatty acid import protein 1 Peroxisomal long-chain fatty acid import protein 2 Peroxisomal membrane protein import receptor PEX19 Probable ATP-dependent permease Uncharacterized ABC transporter ATP-binding protein/permease YOL075C	P25371 P28795 P34230 P41909 Q07418 Q08234	ADP1 PAL1 PAS12 PAS3 PAT1 PAT2 PEX19 PEX3 PXA1 PXA2 SSH2 YOL075C	Saccharomyces cerevisiae (brewer's yeast)
ABC-family proteins mediated transport	ABC transporter ATP-binding protein/permease VMR1 ABC transporter NFT1 ATP-dependent bile acid permease Bile pigment transporter 1 Eukaryotic translation initiation factor 2 subunit alpha Eukaryotic translation initiation factor 2 subunit beta Eukaryotic translation initiation factor 2 subunit gamma Metal resistance protein YCF1 Oligomycin resistance ATP-dependent permease YOR1 [NU+] prion formation protein 1	P09064 P0CE68 P14772 P20459 P32386 P32481 P38735 P39109 P53049 Q08972	BAT1 BPT1 GCD11 NEW1 NFT1 SUI2 SUI3 SUI4 TIF211 TIF212 TIF213 VMR1 YBT1 YCF1 YOR1 YRS1	Saccharomyces cerevisiae (brewer's yeast)
ADP signalling through P2Y purinoceptor 1	Guanine nucleotide-binding protein alpha-1 subunit Lysophospholipase 1 Lysophospholipase 2 Lysophospholipase 3 Mitogen-activated protein kinase HOG1 Putative meiotic phospholipase SPO1	P08539 P32485 P39105 P53541 Q03674 Q08108	CDC70 DAC1 GPA1 HOG1 PLB1 PLB2 PLB3 SCG1 SPO1 SSK3	Saccharomyces cerevisiae (brewer's yeast)
APAP ADME	ABC transporter ATP-binding protein/permease VMR1 ABC transporter NFT1 ATP-dependent bile acid permease Bile pigment transporter 1 Cys-Gly metallodipeptidase DUG1 Glutathione hydrolase proenzyme Metal resistance protein YCF1 Oligomycin resistance ATP-dependent permease YOR1 Probable ATP-dependent permease	P0CE68 P14772 P25371 P32386 P38735 P39109 P43616 P53049 Q05902	ADP1 BAT1 BPT1 CIS2 DUG1 ECM38 NFT1 VMR1 YBT1 YCF1 YOR1 YRS1	Saccharomyces cerevisiae (brewer's yeast)
Activation of ATR in response to replication stress	Cell division control protein 45 Cell division control protein 6 Cell division control protein 7 Checkpoint protein RAD24 Cyclin-dependent kinase 1 DDK kinase regulatory subunit DBF4 DNA damage checkpoint control protein MEC3 DNA damage checkpoint control protein RAD17 DNA damage checkpoint protein 1 DNA replication licensing factor MCM2 DNA replication licensing factor MCM3 DNA replication licensing factor MCM4 DNA replication licensing factor MCM6 DNA replication licensing factor MCM7 M-phase inducer phosphatase Mediator of replication checkpoint protein 1 Minichromosome maintenance protein 10 Minichromosome maintenance protein 5 Origin recognition complex subunit 1 Origin recognition complex subunit 2 Origin recognition complex subunit 3 Origin recognition complex subunit 4 Origin recognition complex subunit 5 Replication factor A protein 1 Replication factor A protein 2 Replication factor C subunit 2 Replication factor C subunit 3 Replication factor C subunit 4 Replication factor C subunit 5 Serine/threonine-protein kinase KSP1	P00546 P06243 P09119 P22336 P23748 P24279 P25588 P26754 P29469 P29496 P30665 P32325 P32354 P32641 P32833 P38132 P38251 P38629 P38691 P40339 P40348 P48581 P50874 P53091 P54784 P54790 P54791 Q02574 Q08032 Q08949	BUF1 BUF2 CDC28 CDC45 CDC46 CDC47 CDC54 CDC6 CDC7 CDK1 DBF4 DDC1 DNA43 DNA52 HCD21 HSL5 KSP1 MCM10 MCM2 MCM3 MCM4 MCM5 MCM6 MCM7 MEC3 MIH1 MRC1 OAF1 OAF2 OIF1 ORC1 ORC2 ORC3 ORC4 ORC5 PIP3 PSO9 RAD17 RAD24 RFA1 RFA2 RFC2 RFC3 RFC4 RFC5 RPA1 RRR1 SIR5 SLD4 SRM5	Saccharomyces cerevisiae (brewer's yeast)
Activation of the AP-1 family of transcription factors	ATF/CREB activator 1 ATF/CREB activator 2 CRE-binding bZIP protein SKO1 General control transcription factor GCN4 Mitogen-activated protein kinase FUS3 Mitogen-activated protein kinase HOG1 Mitogen-activated protein kinase KSS1 Mitogen-activated protein kinase SLT2/MPK1 Sporulation-specific mitogen-activated protein kinase SMK1	P03069 P14681 P16892 P32485 P39970 P40535 P41808 Q00772 Q02100	AAS101 AAS3 ACA1 ACA2 ACR1 ARG9 CST6 DAC2 FUS3 GCN4 HOG1 KSS1 MPK1 SKO1 SLT2 SMK1 SSK3	Saccharomyces cerevisiae (brewer's yeast)
Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S	ATP-dependent RNA helicase eIF4A Eukaryotic initiation factor 4F subunit p150 Eukaryotic translation initiation factor 4B Eukaryotic translation initiation factor 4E Nucleolar protein 13	P07260 P10081 P34167 P39935 P53883	CDC33 NOP13 STM1 TIF1 TIF2 TIF3 TIF41A TIF41B TIF42 TIF45 TIF4631	Saccharomyces cerevisiae (brewer's yeast)
Activation of the pre-replicative complex	Cell division control protein 45 Cell division control protein 6 Cell division control protein 7 Cyclin-dependent kinase 1 DDK kinase regulatory subunit DBF4 DNA polymerase alpha catalytic subunit A DNA polymerase alpha subunit B DNA polymerase epsilon catalytic subunit A DNA polymerase epsilon subunit B DNA polymerase epsilon subunit C DNA polymerase epsilon subunit D DNA primase large subunit DNA primase small subunit DNA replication licensing factor MCM2 DNA replication licensing factor MCM3 DNA replication licensing factor MCM4 DNA replication licensing factor MCM6 DNA replication licensing factor MCM7 Minichromosome maintenance protein 10 Minichromosome maintenance protein 5 Origin recognition complex subunit 1 Origin recognition complex subunit 2 Origin recognition complex subunit 3 Origin recognition complex subunit 4 Origin recognition complex subunit 5 Protein DLS1 Replication factor A protein 1 Replication factor A protein 2	P00546 P06243 P09119 P10363 P13382 P20457 P21951 P22336 P24279 P24482 P26754 P27344 P29469 P29496 P30665 P32325 P32354 P32833 P38121 P38132 P40366 P50874 P53091 P54784 P54790 P54791 Q04603 Q08032	BUF1 BUF2 CDC17 CDC28 CDC45 CDC46 CDC47 CDC54 CDC6 CDC7 CDK1 DBF4 DLS1 DNA43 DNA52 DPB2 DPB3 DPB4 DUN2 HCD21 HSL5 MCM10 MCM2 MCM3 MCM4 MCM5 MCM6 MCM7 OAF1 OAF2 OIF1 ORC1 ORC2 ORC3 ORC4 ORC5 POL1 POL12 POL2 PRI1 PRI2 RFA1 RFA2 RPA1 RRR1 SIR5 SLD4 SRM5	Saccharomyces cerevisiae (brewer's yeast)
Acyl chain remodeling of CL	2-acyl-1-lysophosphatidylinositol acyltransferase Lysophospholipase 1 Lysophospholipase 2 Lysophospholipase 3 Putative meiotic phospholipase SPO1 Tafazzin	P38226 P39105 P53541 Q03674 Q06510 Q08108	CST26 PLB1 PLB2 PLB3 PSI1 SPO1 TAZ1	Saccharomyces cerevisiae (brewer's yeast)
Acyl chain remodeling of DAG and TAG	Diacylglycerol O-acyltransferase 1 Monoglyceride lipase	P28321 Q08650	DGA1 YJU3	Saccharomyces cerevisiae (brewer's yeast)
Acyl chain remodelling of PC	Lysophospholipase 1 Lysophospholipase 2 Lysophospholipase 3 Lysophospholipid acyltransferase Putative meiotic phospholipase SPO1	P39105 P53541 Q03674 Q08108 Q08548	ALE1 LCA1 LPT1 PLB1 PLB2 PLB3 SLC4 SPO1	Saccharomyces cerevisiae (brewer's yeast)
Acyl chain remodelling of PE	Cardiolipin-specific deacylase 1, mitochondrial Lysophospholipase 1 Lysophospholipase 2 Lysophospholipase 3 Lysophospholipid acyltransferase Putative meiotic phospholipase SPO1	P39105 P53264 P53541 Q03674 Q08108 Q08548	ALE1 CLD1 LCA1 LPT1 PLB1 PLB2 PLB3 SLC4 SPO1	Saccharomyces cerevisiae (brewer's yeast)
Acyl chain remodelling of PG	2-acyl-1-lysophosphatidylinositol acyltransferase Cardiolipin synthase (CMP-forming) Lysophospholipase 1 Lysophospholipase 2 Lysophospholipase 3 Putative meiotic phospholipase SPO1 Uncharacterized acyltransferase YDR018C	P38226 P39105 P53541 Q03674 Q07560 Q08108 Q12185	CLS1 CRD1 CST26 PLB1 PLB2 PLB3 PSI1 SPO1 YDR018C	Saccharomyces cerevisiae (brewer's yeast)
Acyl chain remodelling of PI	Lysophospholipase 1 Lysophospholipase 2 Lysophospholipase 3 Lysophospholipid acyltransferase Putative meiotic phospholipase SPO1	P39105 P53541 Q03674 Q08108 Q08548	ALE1 LCA1 LPT1 PLB1 PLB2 PLB3 SLC4 SPO1	Saccharomyces cerevisiae (brewer's yeast)
Acyl chain remodelling of PS	Lysophospholipase 1 Lysophospholipase 2 Lysophospholipase 3 Lysophospholipid acyltransferase Oxysterol-binding protein homolog 4 Oxysterol-binding protein homolog 5 Oxysterol-binding protein homolog 6 Oxysterol-binding protein homolog 7 Putative meiotic phospholipase SPO1	P35843 P35844 P38755 P39105 P53541 Q02201 Q03674 Q08108 Q08548	ALE1 BSR3 HES1 KES1 LCA1 LPT1 OSH4 OSH5 OSH6 OSH7 PLB1 PLB2 PLB3 SLC4 SPO1	Saccharomyces cerevisiae (brewer's yeast)
Aflatoxin activation and detoxification	Glutathione hydrolase proenzyme	Q05902	CIS2 ECM38	Saccharomyces cerevisiae (brewer's yeast)
Amino acid transport across the plasma membrane	High-affinity methionine permease Low-affinity methionine permease Oligo-1,6-glucosidase IMA2 Oligo-1,6-glucosidase IMA3 Oligo-1,6-glucosidase IMA4 Probable transporter MCH2 Probable transporter MCH4 Riboflavin transporter MCH5 Uncharacterized transporter ESBP6 Vacuolar amino acid transporter 2 Vacuolar amino acid transporter 4	P0CW40 P0CW41 P36032 P38734 P39981 P50276 P50944 P53918 Q08268 Q08295 Q08777	AVT2 AVT4 ESBP6 FSP2 IMA2 IMA3 IMA4 MCH2 MCH3 MCH4 MCH5 MUP1 MUP3	Saccharomyces cerevisiae (brewer's yeast)
Antigen processing: Ubiquitination & Proteasome degradation	26S proteasome regulatory subunit 4 homolog 26S proteasome regulatory subunit 6A 26S proteasome regulatory subunit 6B homolog 26S proteasome regulatory subunit 7 homolog 26S proteasome regulatory subunit 8 homolog 26S proteasome regulatory subunit RPN12 26S proteasome regulatory subunit RPN1 26S proteasome regulatory subunit RPN2 26S proteasome regulatory subunit RPN3 26S proteasome regulatory subunit RPN5 26S proteasome regulatory subunit RPN6 26S proteasome regulatory subunit RPN7 26S proteasome regulatory subunit RPN8 26S proteasome regulatory subunit RPN9 26S proteasome subunit RPT4 APC/C activator protein CDC20 APC/C activator protein CDH1 Aminopeptidase 2, mitochondrial Anaphase-promoting complex subunit 11 Anaphase-promoting complex subunit 1 Anaphase-promoting complex subunit 2 Anaphase-promoting complex subunit 4 Anaphase-promoting complex subunit 5 Anaphase-promoting complex subunit CDC16 Anaphase-promoting complex subunit CDC23 Anaphase-promoting complex subunit CDC27 Anaphase-promoting complex subunit DOC1 Cell division control protein 53 Cysteine proteinase 1, mitochondrial E3 ubiquitin-protein ligase HEL1 E3 ubiquitin-protein ligase HUL5 E3 ubiquitin-protein ligase ITT1 E3 ubiquitin-protein ligase RSP5 E3 ubiquitin-protein ligase TOM1 E3 ubiquitin-protein ligase UBR1 E3 ubiquitin-protein ligase UBR2 E3 ubiquitin-protein ligase listerin E4 ubiquitin-protein ligase UFD2 Elongin-C F-box protein HRT3 F-box protein YDR306C F-box protein YLR352W NEDD8-activating enzyme E1 catalytic subunit NEDD8-conjugating enzyme UBC12 Nuclear distribution protein PAC1 Phosphate system positive regulatory protein PHO81 Polyubiquitin Probable 26S proteasome regulatory subunit p27 Probable E3 ubiquitin-protein ligase HUL4 Probable proteasome subunit alpha type-7 Proteasome activator BLM10 Proteasome subunit alpha type-1 Proteasome subunit alpha type-2 Proteasome subunit alpha type-3 Proteasome subunit alpha type-4 Proteasome subunit alpha type-5 Proteasome subunit alpha type-6 Proteasome subunit beta type-1 Proteasome subunit beta type-2 Proteasome subunit beta type-3 Proteasome subunit beta type-4 Proteasome subunit beta type-5 Proteasome subunit beta type-7 Protein HOS4 Protein MPE1 RING-box protein HRT1 Saccharolysin Suppressor of kinetochore protein 1 Ubiquitin carboxyl-terminal hydrolase RPN11 Ubiquitin fusion degradation protein 4 Ubiquitin ligase complex F-box protein UFO1 Ubiquitin-activating enzyme E1 1 Ubiquitin-conjugating enzyme E2 13 Ubiquitin-conjugating enzyme E2 1 Ubiquitin-conjugating enzyme E2 2 Ubiquitin-conjugating enzyme E2 4 Ubiquitin-conjugating enzyme E2 6 Ubiquitin-conjugating enzyme E2 7 Ubiquitin-conjugating enzyme E2-16 kDa Ubiquitin-conjugating enzyme E2-18 kDa Ubiquitin-conjugating enzyme E2-24 kDa Ubiquitin-conjugating enzyme E2-34 kDa Ubiquitin-conjugating enzyme variant MMS2 Ubiquitin-like modifier-activating enzyme ATG7 Uncharacterized protein YJR141W [PSI+] inducibility protein 3	P06104 P09798 P0CG63 P14682 P15731 P15732 P16522 P17442 P19812 P21242 P21243 P21734 P22141 P22515 P23638 P23639 P25043 P25375 P25451 P26309 P28263 P30656 P30657 P32379 P32454 P32496 P32565 P33202 P33296 P33297 P33298 P33299 P35728 P36113 P38042 P38624 P38764 P38862 P39940 P39946 P40016 P40302 P40303 P40327 P40480 P40555 P40985 P43583 P43588 P47172 P52286 P52490 P52491 P52492 P53068 P53119 P53152 P53197 P53549 P53886 P54860 Q01532 Q01939 Q02159 Q03071 Q03280 Q04062 Q04511 Q04601 Q04638 Q04781 Q06103 Q06449 Q06479 Q06640 Q07963 Q08273 Q08683 Q08723 Q12018 Q12157 Q12250 Q12347 Q12377 Q12440 Q99344	APC1 APC10 APC11 APC2 APC3 APC4 APC5 APE2 APG7 ATG7 BLH1 BLM10 BLM3 CBF3D CDC16 CDC20 CDC23 CDC27 CDC34 CDC53 CDH1 CIM3 CIM5 CRL13 CRL3 CVT2 DNA6 DOA2 DOA3 DOA5 DOC1 ELC1 GAL6 GID3 HCT1 HEL1 HOS4 HRD2 HRT1 HRT3 HUL4 HUL5 ITT1 LAP1 LAP3 LIS1 LSB2 LTN1 MDP1 MMS2 MPE1 MPR1 NAS1 NAS2 NAS4 NAS5 NAS7 NIN1 NPI1 PAC1 PCS1 PHO81 PIN3 PRC1 PRC2 PRD1 PRE1 PRE10 PRE2 PRE3 PRE4 PRE5 PRE6 PRE8 PRE9 PRG1 PRS1 PRS2 PRS4 PRS5 PTR1 PUP1 PUP2 PUP3 QRI8 RAD6 RBX1 RKR1 RMC1 ROC1 RPD1 RPN1 RPN11 RPN12 RPN2 RPN3 RPN5 RPN6 RPN7 RPN8 RPN9 RPT1 RPT2 RPT3 RPT4 RPT5 RPT6 RSI1 RSP5 SCD2 SCL1 SEN3 SKP1 SNB1 SSR2 SUG1 SUG2 SUN2 TBPY TBY1 TOM1 UBA1 UBA3 UBC1 UBC11 UBC12 UBC13 UBC2 UBC3 UBC4 UBC5 UBC6 UBC7 UBC8 UBI4 UBR1 UBR2 UFD2 UFD4 UFO1 YCP1 YDR306C YHS4 YJR141W YLR352W YNT1 YTA1 YTA2 YTA3 YTA5	Saccharomyces cerevisiae (brewer's yeast)
Apoptotic execution phase	Dynamin-related protein DNM1 Endoplasmic reticulum transmembrane protein 3 Serine/threonine-protein kinase KIC1	P38692 P54861 Q07451	DNM1 KIC1 NRK1 YET3	Saccharomyces cerevisiae (brewer's yeast)
Arachidonic acid metabolism	Diacylglycerol O-acyltransferase 1 Lysophospholipase 1 Lysophospholipase 2 Lysophospholipase 3 Putative meiotic phospholipase SPO1	P39105 P53541 Q03674 Q08108 Q08650	DGA1 PLB1 PLB2 PLB3 SPO1	Saccharomyces cerevisiae (brewer's yeast)
Aspartate and asparagine metabolism	Asparagine synthetase [glutamine-hydrolyzing] 1 Asparagine synthetase [glutamine-hydrolyzing] 2 Aspartate aminotransferase, cytoplasmic Aspartate aminotransferase, mitochondrial Mitochondrial aspartate-glutamate transporter AGC1 Putative zinc metalloprotease TRE2 Uncharacterized protein TRE1 Vacuolar protein sorting-associated protein 70	P23542 P47161 P49089 P49090 Q01802 Q08693 Q08919 Q12482	AAT1 AAT2 AGC1 ASN1 ASN2 ASP5 TRE1 TRE2 VPS70	Saccharomyces cerevisiae (brewer's yeast)
Aspirin ADME	ABC transporter ATP-binding protein/permease VMR1 ABC transporter NFT1 ATP-dependent bile acid permease Bile pigment transporter 1 Metal resistance protein YCF1 Oligomycin resistance ATP-dependent permease YOR1	P0CE68 P14772 P32386 P38735 P39109 P53049	BAT1 BPT1 NFT1 VMR1 YBT1 YCF1 YOR1 YRS1	Saccharomyces cerevisiae (brewer's yeast)
Assembly of the pre-replicative complex	DNA replication licensing factor MCM2 DNA replication licensing factor MCM3 DNA replication licensing factor MCM4 DNA replication licensing factor MCM6 DNA replication licensing factor MCM7 Minichromosome maintenance protein 5	P24279 P29469 P29496 P30665 P38132 P53091	CDC46 CDC47 CDC54 HCD21 MCM2 MCM3 MCM4 MCM5 MCM6 MCM7	Saccharomyces cerevisiae (brewer's yeast)
Association of TriC/CCT with target proteins during biosynthesis	Sphingoid long chain base kinase 5 T-complex protein 1 subunit alpha T-complex protein 1 subunit beta T-complex protein 1 subunit delta T-complex protein 1 subunit epsilon T-complex protein 1 subunit eta T-complex protein 1 subunit gamma T-complex protein 1 subunit theta T-complex protein 1 subunit zeta	P12612 P39076 P39077 P39078 P39079 P40413 P42943 P47079 Q06147	ANC2 BIN2 BIN3 CCT1 CCT2 CCT3 CCT4 CCT5 CCT6 CCT7 CCT8 LCB5 TCP1 TCP2 TCP20 TCP3 TCP4 TCP5 TCP6	Saccharomyces cerevisiae (brewer's yeast)
Atorvastatin ADME	ABC transporter ATP-binding protein/permease VMR1 ABC transporter NFT1 ATP-dependent bile acid permease Bile pigment transporter 1 Metal resistance protein YCF1 Oligomycin resistance ATP-dependent permease YOR1	P0CE68 P14772 P32386 P38735 P39109 P53049	BAT1 BPT1 NFT1 VMR1 YBT1 YCF1 YOR1 YRS1	Saccharomyces cerevisiae (brewer's yeast)

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