GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	March 20, 2024
ECODAB	April 1, 2019

Displaying entries **326 - 350** of **360** in total

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Pathway Name	Protein Name	UniProt ID	Gene Symbol	Organism ▲	GlyTouCan ID
Hyaluronan uptake and degradation	Beta-glucuronidase Beta-hexosaminidase Beta-hexosaminidase CD44 antigen Hyaluronan mediated motility receptor Hyaluronidase Hyaluronidase Lymphatic vessel endothelial hyaluronan receptor 1 Sodium/hydrogen exchanger Stabilin 2	A0A287A7V3 A0A5G2RBP4 A0A5K1TZ96 D0G6X8 F1SGT4 F1SPN9 F1SRK1 F1STQ3 I3LTD0 Q4FAT7	CD44 GUSB HEXA HEXB HMMR HYAL1 HYAL2 LYVE1 SLC9A1 STAB2	Sus scrofa (pig)	G35674CY
Post-translational modification: synthesis of GPI-anchored proteins	ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase Alkaline phosphatase Alkaline phosphatase CAMPATH-1 antigen CD109 antigen isoform 1 preproprotein Carboxypeptidase M Carcinoembryonic antigen-related cell adhesion molecule 21 Contactin 4 Contactin-5 Dimethylarginine dimethylaminohydrolase 2 Fc fragment of IgG receptor IIIa Folate receptor 2 (fetal) Glycoprotein 2 Ig-like domain-containing protein Ig-like domain-containing protein LY6/PLAUR domain containing 1 LY6/PLAUR domain containing 3 LY6/PLAUR domain containing 4 LY6/PLAUR domain containing 5 LY6/PLAUR domain containing 8 LY6E Limbic system associated membrane protein Lymphocyte antigen 6 complex G6D Lymphocyte antigen 6 family member K MAM domain containing glycosylphosphatidylinositol anchor 1 Melanotransferrin NAD(P)(+)--arginine ADP-ribosyltransferase NAD(P)(+)--arginine ADP-ribosyltransferase Neuritin 1 like Neuritin 1 Neuronal growth regulator 1 Neurotrimin Opioid binding protein/cell adhesion molecule like Otoancorin Pantetheinase Peptidase S1 domain-containing protein Phosphatidylinositol-glycan-specific phospholipase D Placenta-expressed transcript 1 protein Prion like protein doppel Prostate stem cell antigen Reticulon 4 receptor like 1 Reversion inducing cysteine rich protein with kazal motifs Shadow of prion protein Sperm acrosome associated 4 Tectorin beta Testis expressed 101 Thy-1 membrane glycoprotein UL16 binding protein Uncharacterized protein Xaa-Pro aminopeptidase 2 alkaline phosphatase alkaline phosphatase	A0A076V5Y0 A0A286ZPV1 A0A287A6H7 A0A287AAC2 A0A287ADZ3 A0A287AE72 A0A287AF84 A0A287ALH7 A0A287AMR3 A0A287ANC0 A0A287AW11 A0A287B2P9 A0A287B6K9 A0A287BA17 A0A287BEC3 A0A287BPP1 A0A287BSC3 A0A5G2QLX9 A0A5G2QTH8 A0A5G2QZJ2 A0A5G2R2D6 A0A5G2RDD8 A0A5G2RDM2 A0A5G2RN46 A0A5K1UHA8 A0A8W4FAB7 A0A8W4FC76 A0A8W4FFP4 A0A8W4FJ49 A0A8W4FNK2 B9TSR2 D3K5J4 D5K890 F1RMU7 F1RMV7 F1RPA7 F1RPE9 F1RUE4 F1RVR8 F1S3Q7 F1S5L3 F1S5V7 F1SQX4 I3L9E5 I3LEZ3 I3LQE2 I6L5V9 K7GKY0 M3TYM6 Q7YQE5 Q95333 Q95N22	ALPL ART3 ART4 BST1 CD109 CD52 CEACAM1 CEACAM21 CNTN4 CNTN5 CPM DDAH2 FCGR3A FOLR2 GP2 GPLD1 LOC100157453 LOC100521229 LOC100522404 LSAMP LY6E LY6G6C LY6G6D LY6K LYPD1 LYPD3 LYPD4 LYPD5 LYPD8 MDGA1 MELTF NEGR1 NRN1 NRN1L NTM OPCML OTOA PLET1 PRND PSCA RECK RTN4RL1 SPACA4 SPRN TECTB TEX101 THY1 ULBP1 VNN1 XPNPEP2 ly6g6d	Sus scrofa (pig)
SHC-mediated cascade:FGFR4	Fibroblast growth factor 23 Fibroblast growth factor 9 Fibroblast growth factor receptor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor GTPase HRas GTPase NRas Growth factor receptor bound protein 2 Klotho beta Multifunctional fusion protein SHC-transforming protein 1 SOS Ras/Rac guanine nucleotide exchange factor 1 small monomeric GTPase	A0A286ZUQ0 A0A287AFX3 A0A287AXR0 A0A287B3V5 A0A287BGK8 A0A5G2QLX0 A0A5G2QUY7 A0A5G2R7G2 A0A5K1V5Y3 B6E241 F1RM38 F1RY80 F1S3B8 F1SET9 I3L560 I3LCQ9 I3LR27 Q2MJK3 Q95L12	FGF1 FGF16 FGF18 FGF19 FGF2 FGF20 FGF23 FGF4 FGF6 FGF8 FGF9 FGFR4 Fgf4 GRB2 HRAS KLB KRAS NRAS SHC1 SOS1	Sus scrofa (pig)
Interleukin-1 signaling	26S protease regulatory subunit 4 26S proteasome non-ATPase regulatory subunit 11 26S proteasome non-ATPase regulatory subunit 13 26S proteasome non-ATPase regulatory subunit 1 26S proteasome non-ATPase regulatory subunit 2 26S proteasome non-ATPase regulatory subunit 3 26S proteasome non-ATPase regulatory subunit 4 26S proteasome non-ATPase regulatory subunit 6 26S proteasome non-ATPase regulatory subunit 8 26S proteasome non-ATPase regulatory subunit 9 26S proteasome regulatory subunit 8 Cullin 1 E3 ubiquitin-protein ligase RBX1 E3 ubiquitin-protein ligase pellino homolog E3 ubiquitin-protein ligase pellino homolog IkappaB kinase Inhibitor of nuclear factor kappa-B kinase subunit alpha Interleukin 1 receptor associated kinase 3 Interleukin 1 receptor type 1 Interleukin 1 receptor type 2 Interleukin-1 alpha Interleukin-1 beta Interleukin-1 receptor-associated kinase 4 Interleukin-1 receptor-associated kinase-like 2 Mitogen-activated protein kinase kinase kinase 3 Mitogen-activated protein kinase kinase kinase 7 Multifunctional fusion protein Multifunctional fusion protein Multifunctional fusion protein Multifunctional fusion protein Multifunctional fusion protein Multifunctional fusion protein Myeloid differentiation primary response protein MyD88 NF-kappa-B essential modulator NF-kappa-B inhibitor alpha Nuclear factor NF-kappa-B p105 subunit Polyubiquitin-C Proteasome 20S subunit alpha 2 Proteasome 26S subunit, ATPase 3 Proteasome 26S subunit, ATPase 6 Proteasome 26S subunit, non-ATPase 14 Proteasome 26S subunit, non-ATPase 7 Proteasome activator complex subunit 1 Proteasome activator complex subunit 2 Proteasome activator complex subunit 3 Proteasome activator complex subunit 4 Proteasome inhibitor PI31 subunit Proteasome subunit alpha type Proteasome subunit alpha type Proteasome subunit alpha type Proteasome subunit alpha type Proteasome subunit alpha type Proteasome subunit alpha type Proteasome subunit beta type-7 Proteasome subunit beta Proteasome subunit beta Proteasome subunit beta Proteasome subunit beta Proteasome subunit beta RELA proto-oncogene, NF-kB subunit S-phase kinase-associated protein 1 Sequestosome 1 TGF-beta activated kinase 1 (MAP3K7) binding protein 1 TGF-beta activated kinase 1 (MAP3K7) binding protein 2 TGF-beta activated kinase 1 (MAP3K7) binding protein 3 TNF receptor-associated factor 6 Toll interacting protein UBC core domain-containing protein Ubiquitin B Ubiquitin C Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein Uncharacterized protein mitogen-activated protein kinase kinase non-specific serine/threonine protein kinase	A0A140TAK4 A0A286ZLP7 A0A286ZMM6 A0A286ZMX3 A0A286ZN52 A0A286ZS34 A0A287A3T1 A0A287A5Q1 A0A287AEH0 A0A287AF06 A0A287AFR7 A0A287AGW3 A0A287APQ3 A0A287ARU4 A0A287AVR3 A0A287AZA7 A0A287B1K0 A0A287B501 A0A287B5Q7 A0A287B6X4 A0A287BG14 A0A287BLE1 A0A287BPP9 A0A287BRB4 A0A287BRR7 A0A287BRV0 A0A288CG47 A0A2C9F3A1 A0A2C9F3G2 A0A480JRT9 A0A480L492 A0A481CGW8 A0A5G2QF58 A0A5G2QI19 A0A5G2QL81 A0A5G2QSI4 A0A5G2QSU8 A0A5G2QZC6 A0A5G2R6X9 A0A8W4FHK5 A0A8W4FNV3 A1XQU1 A7U5U2 A7XUJ6 A9QT41 B0LXP5 F1RKW8 F1RPQ3 F1RV28 F1RXA7 F1RZU1 F1S7S1 F1S8V5 F1S911 F1S9C7 F1SBA5 F1SGF1 F1SGM3 F1SMW9 F1SUB9 F2Z5J1 F2Z5K2 F2Z5N0 F6PVF4 F6Q7E6 I3LE48 K7GLB8 P0CG68 P18430 P26889 P61291 P62197 Q08353 Q2PYM7 Q64L94	CHUK CUL1 IKBA IKBKB IKBKG IL1A IL1B IL1B2 IL1R1 IL1R2 IRAK1 IRAK2 IRAK3 IRAK4 LMP2 LOC110255300 LOC110258125 LOC110258578 LOC110259156 MAP2K6 MAP3K3 MAP3K7 MYD88 NFKB1 NFKBIA PELI2 PELI3 PRORP PSMA1 PSMA2 PSMA4 PSMA5 PSMA6 PSMA7 PSMA8 PSMB1 PSMB10 PSMB11 PSMB3 PSMB7 PSMB9 PSMC1 PSMC3 PSMC5 PSMC6 PSMD1 PSMD11 PSMD13 PSMD14 PSMD2 PSMD3 PSMD4 PSMD6 PSMD7 PSMD8 PSMD9 PSME1 PSME2 PSME3 PSME4 PSMF1 RBX1 RELA RPS27A SKP1 SQSTM1 TAB1 TAB2 TAB3 TAK1b TOLLIP TRAF6 UBA52 UBB UBC UBE2NL	Sus scrofa (pig)
Abacavir transmembrane transport	Solute carrier family 22 member 1 Solute carrier family 22 member 2 Solute carrier family 22 member 3	A0A287A9U9 F1SB80 O02713	OCT2 SLC22A1 SLC22A2 SLC22A3	Sus scrofa (pig)
N-glycan trimming in the ER and Calnexin/Calreticulin cycle	26S protease regulatory subunit 4 Autocrine motility factor receptor Peptide-N(4)-(N-acetyl-beta-glucosaminyl)asparagine amidase Polyubiquitin-C UBX domain protein 1 Ubiquitin B Ubiquitin C Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase	A0A287AZA7 A0A2C9F3G2 A0A480HSN1 A0A5G2QHB2 A7U5U2 F1RF19 F1RS44 F1S911 F2Z5J1 P0CG68	AMFR ENGASE NGLY1 PSMC1 RPS27A UBA52 UBB UBC UBXN1	Sus scrofa (pig)	G03934XO G25577BM G28233ME G51034LA G86419OL
Antagonism of Activin by Follistatin	Follistatin Follistatin Inhibin beta A chain Inhibin beta B chain	A0A287BPF5 F1SLQ4 P03970 P10669	FST INHBA INHBB	Sus scrofa (pig)
Sulfur amino acid metabolism	Adenosylhomocysteinase Betaine--homocysteine S-methyltransferase 1 Betaine--homocysteine S-methyltransferase 2 Methionine synthase reductase Methionine synthase S-adenosylmethionine synthase	A0A287ABJ0 A0A287B4J2 E7D6R2 F1RHM1 F1S0T1 F1SER1	AHCY BHMT BHMT2 MAT1A MTR MTRR bhmt	Sus scrofa (pig)
RAF/MAP kinase cascade	Actinin alpha 2 Amphiregulin Angiopoietin-1 Artemin Astrocytic phosphoprotein PEA-15 Betacellulin Calcium/calmodulin-dependent protein kinase type II subunit delta Calmodulin 3 Cell division cycle 25C Colony stimulating factor 2 receptor subunit beta Discs large MAGUK scaffold protein 3 Discs large MAGUK scaffold protein 4 Disks large homolog 1 Epiregulin Fibroblast growth factor 23 Fibroblast growth factor 9 Fibroblast growth factor receptor substrate 3 Fibroblast growth factor receptor Fibroblast growth factor receptor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibronectin type-III domain-containing protein Fms related receptor tyrosine kinase 3 ligand GDNF family receptor alpha 1 GDNF family receptor alpha 4 GDNF family receptor alpha-2 GTPase HRas GTPase NRas Glial cell derived neurotrophic factor Glutamate receptor Glutamate receptor Glutamate receptor Granulocyte-macrophage colony-stimulating factor Growth factor receptor bound protein 2 Hepatocyte growth factor receptor Hepatocyte growth factor Insulin receptor substrate 1 Insulin receptor substrate 2 Interleukin 2 receptor gamma Interleukin 5 receptor subunit alpha Interleukin-2 receptor subunit alpha Interleukin-2 receptor subunit beta Interleukin-2 Interleukin-5 Kit ligand Klotho beta Klotho Leucine rich repeat containing 7 Linker for activation of T cells Mast/stem cell growth factor receptor Mitogen-activated protein kinase Mitogen-activated protein kinase Multifunctional fusion protein Neuregulin 2 Neuregulin 3 Neurofilament light polypeptide Neurturin Outer dynein arm docking complex subunit 3 Persephin Phosphatidylinositol 3-kinase regulatory subunit alpha isoform 2 Phosphatidylinositol 3-kinase regulatory subunit beta Platelet-derived growth factor receptor alpha Platelet-derived growth factor receptor beta Platelet-derived growth factor subunit A Platelet-derived growth factor subunit B Pro-epidermal growth factor Pro-neuregulin-1, membrane-bound isoform Proheparin-binding EGF-like growth factor Proto-oncogene tyrosine-protein kinase receptor Ret RAS guanyl releasing protein 4 RAS guanyl-releasing protein 1 Ral guanine nucleotide dissociation stimulator like 1 Ral guanine nucleotide dissociation stimulator like 2 Ral guanine nucleotide dissociation stimulator Ran-binding protein 9 Ras protein specific guanine nucleotide releasing factor 1 Ras protein specific guanine nucleotide releasing factor 2 Ras-GEF domain-containing family member 1A isoform 1 Receptor protein-tyrosine kinase Receptor protein-tyrosine kinase Receptor protein-tyrosine kinase Receptor protein-tyrosine kinase Receptor-type tyrosine-protein phosphatase alpha SHC adaptor protein 2 SHC adaptor protein 3 SHC-transforming protein 1 SOS Ras/Rac guanine nucleotide exchange factor 1 Spectrin alpha, erythrocytic 1 Spectrin alpha, non-erythrocytic 1 Spectrin beta chain Spectrin beta chain Spectrin beta, non-erythrocytic 4 Spectrin beta, non-erythrocytic 5 Transforming growth factor alpha Tyrosine-protein kinase Fyn Tyrosine-protein kinase JAK2 Tyrosine-protein kinase Tyrosine-protein kinase calcium/calmodulin-dependent protein kinase calcium/calmodulin-dependent protein kinase calcium/calmodulin-dependent protein kinase phosphatidylinositol-4,5-bisphosphate 3-kinase phosphatidylinositol-4,5-bisphosphate 3-kinase receptor protein-tyrosine kinase receptor protein-tyrosine kinase small monomeric GTPase	A0A286ZJ09 A0A286ZJM1 A0A286ZLI2 A0A286ZUM2 A0A286ZUQ0 A0A286ZXS0 A0A287A231 A0A287A4M5 A0A287A6I2 A0A287A7A4 A0A287AAE4 A0A287AC43 A0A287AC69 A0A287ADF0 A0A287AFR0 A0A287AFW3 A0A287AFX3 A0A287AV68 A0A287AXR0 A0A287AY39 A0A287AYB4 A0A287AZM9 A0A287B0D3 A0A287B3A4 A0A287B3V5 A0A287B5E0 A0A287B726 A0A287B731 A0A287B929 A0A287BCC5 A0A287BCW9 A0A287BDL2 A0A287BDN2 A0A287BEY5 A0A287BFJ1 A0A287BG34 A0A287BGK8 A0A287BNA7 A0A287BQC2 A0A480ECT1 A0A480J3B5 A0A480J4F4 A0A480NH74 A0A5G2QBP1 A0A5G2QCQ9 A0A5G2QEJ3 A0A5G2QLU2 A0A5G2QLX0 A0A5G2QNL8 A0A5G2QT01 A0A5G2QU27 A0A5G2QUY7 A0A5G2QWK6 A0A5G2QY14 A0A5G2R1H6 A0A5G2R7G2 A0A5G2R924 A0A5G2RG05 A0A5K1UB41 A0A5K1V5Y3 A0A8W4F937 A0A8W4FBX1 A0A8W4FMH5 A0A8X9AEI7 A1Y2K1 B6E241 F1RF08 F1RG22 F1RH78 F1RKR6 F1RL74 F1RL75 F1RL86 F1RM38 F1RMZ6 F1RSR6 F1RTL4 F1RUW8 F1RV77 F1RWM5 F1RY78 F1RY80 F1RZT1 F1S3B8 F1S598 F1S916 F1SB93 F1SBT4 F1SET9 F1SFL9 F1SKR9 F1SLD3 F1SMG2 F1SQ84 F1SS17 F1SSQ9 I3L560 I3LCQ9 I3LLF1 I3LR27 K7GMW2 K7GQ34 K7GQJ1 K7GSE8 K7GSP7 O19064 P26891 Q01580 Q29118 Q2MJK3 Q2QLE0 Q76KD0 Q95266 Q95L12 Q9BDH4 Q9MYM5	ACTN2 ANGPT1 AREG ARTN BTC CALM3 CAMK2A CAMK2B CAMK2D CAMK2G CDC25C CSF2 CSF2RA CSF2RB DLG1 DLG3 DLG4 DTR EGF EGFR ERBB2 ERBB3 ERBB4 EREG FGF1 FGF10 FGF16 FGF18 FGF19 FGF2 FGF20 FGF22 FGF23 FGF3 FGF4 FGF5 FGF6 FGF8 FGF9 FGFR1 FGFR4 FLT3 FLT3LG FRS3 FYN Fgf4 GDNF GFRA1 GFRA2 GFRA3 GFRA4 GRB2 GRIN1 GRIN2B GRIN2D HBEGF HEGFL HGF HRAS IL2 IL2RA IL2RB IL2RG IL5 IL5RA IRS1 IRS2 JAK1 JAK2 JAK3 KIT KITLG KL KLB KRAS LAT LRRC7 MAPK1 MAPK3 MET NEFL NRAS NRG1 NRG2 NRG3 NRTN ODAD3 PDGFA PDGFB PDGFRA PDGFRB PEA15 PIK3CA PIK3CB PIK3R1 PIK3R2 PSPN PTPRA RALGDS RANBP9 RASGEF1A RASGRF1 RASGRF2 RASGRP1 RASGRP4 RET RGL1 RGL2 RGL3 SHC1 SHC2 SHC3 SOS1 SPTA1 SPTAN1 SPTBN1 SPTBN2 SPTBN4 SPTBN5 TEK TGFA	Sus scrofa (pig)
TFAP2 (AP-2) family regulates transcription of growth factors and their receptors	ATPase family AAA domain containing 2 Estrogen receptor Glycoprotein hormones alpha chain Lutropin subunit beta	A0A287AQ37 P01219 P01232 Q29040	ATAD2 CGA ESR ESR1 LHB NR3A1	Sus scrofa (pig)
TNFR1-mediated ceramide production	Neutral sphingomyelinase activation associated factor Small ribosomal subunit protein RACK1 Tumor necrosis factor receptor superfamily member 1A Tumor necrosis factor sphingomyelin phosphodiesterase sphingomyelin phosphodiesterase	A0A286ZVH7 A0A287A053 A0A287AXH1 F1RSY4 P23563 P63246	GNB2L1 NSMAF RACK1 SMPD2 SMPD3 TNF TNFA TNFRSF1A TNFSF2	Sus scrofa (pig)
Heme degradation	ABC-type glutathione-S-conjugate transporter Albumin Biliverdin reductase A Biliverdin reductase B Broad substrate specificity ATP-binding cassette transporter ABCG2 Broad substrate specificity ATP-binding cassette transporter ABCG2 Glutathione S-transferase Glutathione S-transferase Glutathione S-transferase Heme oxygenase 1 Multidrug resistance-associated protein 1 Solute carrier organic anion transporter family member Solute carrier organic anion transporter family member glucuronosyltransferase	A0A287ABK7 A0A287AXU5 A0A287BAY9 A0A287BM94 A0A5G2QYS5 A0A5S6GWJ4 A0A8W4FMT0 F1S7C9 F1S8V9 F1SM17 F1SUN1 I3LQH7 P32394 Q8MIB3	ABCC1 ABCC2 ABCG2 ABCG2A ALB BLVRA BLVRB BMDP GSTA1 HMOX1 LOC100526118 SLCO1B2 SLCO1B3 SLCO2B1 UGT1A6	Sus scrofa (pig)
Glycoprotein hormones	Follitropin subunit beta Glycoprotein hormones alpha chain Inhibin alpha chain Inhibin beta A chain Inhibin beta B chain Inhibin beta C chain preproprotein Inhibin subunit beta E Lutropin subunit beta Thyrotropin subunit beta	A0A286ZIJ6 A0A287BPF5 F1SKG1 P01219 P01224 P01228 P01232 P03970 P04087	CGA FSHB INHA INHBA INHBB INHBC INHBE LHB TSHB	Sus scrofa (pig)
SHC1 events in ERBB2 signaling	Betacellulin Epiregulin Neuregulin 2 Neuregulin 3 Pro-epidermal growth factor Pro-neuregulin-1, membrane-bound isoform Proheparin-binding EGF-like growth factor Protein kinase C epsilon type Protein kinase C Receptor protein-tyrosine kinase Receptor protein-tyrosine kinase Receptor protein-tyrosine kinase Receptor protein-tyrosine kinase SHC-transforming protein 1 protein kinase C protein-tyrosine-phosphatase	A0A286ZJM1 A0A287A231 A0A287A6I2 A0A287AZM9 A0A287BBY6 A0A287BCW9 A0A287BKD5 A0A480J4F4 A0A5G2QBP1 A0A5G2R1H6 A0A5K1V5Y3 F1RV14 F1RWM5 F1S5K7 F1SSQ9 Q01580	BTC DTR EGF EGFR ERBB2 ERBB3 ERBB4 EREG HBEGF HEGFL NRG1 NRG2 NRG3 PRKCA PRKCD PRKCE PTPN12 SHC1	Sus scrofa (pig)
Mitochondrial protein degradation	2-oxoglutarate dehydrogenase complex component E1 28S ribosomal protein S2, mitochondrial 3-oxoacyl-[acyl-carrier-protein] synthase, mitochondrial 5-aminolevulinate synthase 60 kDa heat shock protein, mitochondrial ADP/ATP translocase ADP/ATP translocase AFG3 like matrix AAA peptidase subunit 2 ATP synthase subunit O, mitochondrial ATP synthase subunit a ATP synthase subunit alpha, mitochondrial ATP synthase subunit beta ATP synthase subunit gamma ATP synthase subunit ATP-dependent Clp protease ATP-binding subunit clpX-like, mitochondrial ATP-dependent Clp protease proteolytic subunit Acetyl-CoA acetyltransferase, mitochondrial Aconitate hydratase, mitochondrial Acyl-CoA dehydrogenase family member 8 Aldehyde dehydrogenase X, mitochondrial Aldehyde dehydrogenase, mitochondrial Amyloid-beta A4 protein Amyloid-beta precursor protein Arginase Citrate synthase, mitochondrial Cytochrome b-c1 complex subunit 2, mitochondrial Cytochrome c oxidase subunit 1 Cytochrome c oxidase subunit 5A, mitochondrial Cytochrome c oxidase subunit 5B, mitochondrial D-beta-hydroxybutyrate dehydrogenase, mitochondrial D-lactate dehydrogenase (cytochrome) Delta-1-pyrroline-5-carboxylate synthase Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex Dihydrolipoyl dehydrogenase Enoyl-CoA delta isomerase 1 Enoyl-CoA hydratase 1 Essential MCU regulator, mitochondrial Ferrochelatase Fumarate hydratase, mitochondrial Glutamate dehydrogenase 1, mitochondrial Glutamate dehydrogenase HtrA serine peptidase 2 Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial Hydroxymethylglutaryl-CoA synthase, mitochondrial Hydroxysteroid 17-beta dehydrogenase 10 Isocitrate dehydrogenase [NADP] Isocitrate dehydrogenase [NAD] subunit, mitochondrial Large ribosomal subunit protein bL32m Lon protease homolog, mitochondrial Malate dehydrogenase Malic enzyme Mitochondrial-processing peptidase subunit alpha NAD kinase 2, mitochondrial NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2 NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial Paraplegin Propionyl-CoA carboxylase beta chain, mitochondrial Protein-serine/threonine kinase Pyruvate dehydrogenase E1 component subunit alpha Pyruvate dehydrogenase E1 component subunit beta Serine hydroxymethyltransferase Short/branched chain specific acyl-CoA dehydrogenase, mitochondrial Single-stranded DNA-binding protein, mitochondrial Small ribosomal subunit protein uS10m Steroidogenic acute regulatory protein, mitochondrial Stress-70 protein, mitochondrial Succinate--CoA ligase [GDP-forming] subunit beta, mitochondrial Succinyl-CoA Transcription factor A, mitochondrial Twinkle mtDNA helicase Uncharacterized protein isoleucine--tRNA ligase	A0A286ZNN4 A0A286ZNS2 A0A286ZRL1 A0A286ZRT5 A0A286ZTE6 A0A286ZVQ0 A0A286ZYE6 A0A287A6X5 A0A287ADJ2 A0A287ADU8 A0A287AE42 A0A287ALS6 A0A287B1V1 A0A287B3T2 A0A287BA45 A0A287BBX3 A0A287BFS1 A0A287BKR2 A0A287BN31 A0A480KJB8 A0A480QG80 A0A480S312 A0A5G2QFH7 A0A5G2QH34 A0A5G2QQ85 A0A5G2QSU5 A0A5G2RBR3 A0A5G2RDZ2 A0A5K1VBH1 A0A8W4F7C8 A0A8W4FBI6 A0A8W4FBS4 A0A8W4FFM7 A0A8W4FMW6 A0A8W4FNG9 A0A8X9AEI6 F1RPD2 F1RS43 F1RUU2 F1S001 F1SA26 F1SC47 F1SIX5 F1SJ34 F1SJP7 F1SQX8 F1SSH8 F1ST54 F2Z565 I3L7T4 I3LDY5 I3LM75 I3LNP8 I3LP02 I3LTC4 K7GLT8 K7GP28 O02734 O79876 P00348 P00889 P10173 P42174 P79307 P79384 P80021 Q29551 Q2EN81 Q2XQV4 Q35915 Q5D144 Q5Q0U1 Q5S3G4	A4 ACAD8 ACADSB ACAT1 ACO2 AD1 AFG3L2 ALAS1 ALDH18A1 ALDH1B1 ALDH2 APP ARG2 ATP5A1 ATP5A2 ATP5F1A ATP5F1B ATP5F1C ATP5O ATP5PO ATP6 ATPASE6 BDH1 CLPP CLPX COI COX5A COX5B COXI CS DBT DLD ECH1 ECI1 FECH FH GLUD GLUD1 HAD HADH HADHSC HMGCS2 HSD17B10 HSPA9 HSPD1 HTRA2 IARS2 IDH2 IDH3A LDHD LOC100524613 LOC106507363 LOC110255331 LONP1 MDH2 ME2 MRPL32 MRPS10 MRPS2 MT-ATP6 MT-CO1 MTATP6 MTCO1 NADK2 NDUFS1 NDUFS3 OGDH OXCT OXCT1 OXSM PCCB PDHA1 PDHB PDK1 PMPCA SCHAD SCOT SHMT2 SLC25A5 SLC25A6 SMDT1 SPG7 SSBP1 STAR SUCLG2 TFAM TWNK UQCRC2	Sus scrofa (pig)
Phase I - Functionalization of compounds	Aldehyde dehydrogenase Amine oxidase Amine oxidase Amine oxidase Aryl hydrocarbon receptor nuclear translocator 2 Aryl hydrocarbon receptor nuclear translocator Aryl hydrocarbon receptor repressor Aryl hydrocarbon receptor Arylacetamide deacetylase Biphenyl hydrolase like Carbonyl reductase (NADPH) Carboxylesterase 1 Carboxylic ester hydrolase Carboxylic ester hydrolase Carboxylic ester hydrolase Carboxymethylenebutenolidase homolog Cytochrome P450 3A Cytochrome P450 3A Cytochrome P450 3A Cytochrome P450 family 2 subfamily B member 6B Cytochrome b5 type B Diamine oxidase [copper-containing] Epoxide hydrolase 1 Epoxide hydrolase Mitochondrial amidoxime reducing component 2 Mitochondrial amidoxime-reducing component 1 N-ribosyldihydronicotinamide NADH-cytochrome b5 reductase	A0A286ZIQ2 A0A286ZKL1 A0A286ZPA0 A0A287A6V9 A0A287A8N2 A0A287ALY1 A0A287AXR4 A0A287B6R1 A0A287B7I8 A0A2C9F385 A0A480K1W5 A0A5G2QPB6 A0A5G2QRH6 A0A5G2QSC0 A0A5G2QWJ0 A0A5G2RD43 A0A5G2REZ9 F1RF16 F1RWY7 F1S1G7 F1S9I9 F1SDC4 F1SGX4 I3LA57 I3LEX8 I3LF82 P79381 Q9TRC7	AADAC ABP AHR AHRR ALDH3A1 AOC1 AOC2 ARNT ARNT2 BPHL CBR3 CES1 CES3 CMBL CYB5B CYB5R3 CYP2B6B CYP3A22 CYP3A227 CYP3A29 DAO EPHX1 LOC100520329 LOC100736962 LOC110256000 MTARC1 MTARC2 NQO2	Sus scrofa (pig)
Gastrin-CREB signalling pathway via PKC and MAPK	Mitogen-activated protein kinase Mitogen-activated protein kinase Mitogen-activated protein kinase Ribosomal protein S6 kinase Ribosomal protein S6 kinase Ribosomal protein S6 kinase	A0A287A3K5 A0A287BHE2 A0A480NH74 A0A5G2R6J0 A0A5G2RG05 M3VH78	MAPK1 MAPK3 MAPK7 RPS6KA1 RPS6KA2 RPS6KA3	Sus scrofa (pig)
Prolactin receptor signaling	Cullin 1 E3 ubiquitin-protein ligase RBX1 Growth hormone 1 Prolactin receptor Prolactin S-phase kinase-associated protein 1 SH2B adaptor protein 1 Somatotropin Tyrosine-protein kinase JAK2	A0A286ZMM6 A0A287ARU4 A0A287B501 A0A5S6I4D7 F1RFI0 O19064 P01238 P01248 Q6JTA8	CUL1 GH1 JAK2 PRL PRLR RBX1 SH2B1 SKP1	Sus scrofa (pig)
PI-3K cascade:FGFR4	Fibroblast growth factor 23 Fibroblast growth factor 9 Fibroblast growth factor receptor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor GRB2 associated binding protein 1 Growth factor receptor bound protein 2 Klotho beta Multifunctional fusion protein Phosphatidylinositol 3-kinase regulatory subunit alpha isoform 2 Tyrosine-protein phosphatase non-receptor type phosphatidylinositol-4,5-bisphosphate 3-kinase	A0A287AFX3 A0A287AXR0 A0A287B3V5 A0A287BGK8 A0A480LMF4 A0A5G2QUY7 A0A5G2R7G2 A0A5K1UB41 B6E241 F1RM38 F1RY80 F1S3B8 F1SET9 F1SKR9 I3L560 I3LR27 K7GMT0 Q95L12	FGF1 FGF16 FGF18 FGF19 FGF2 FGF20 FGF23 FGF4 FGF6 FGF8 FGF9 FGFR4 Fgf4 GAB1 GRB2 KLB PIK3CA PIK3R1 PTPN11	Sus scrofa (pig)
Extracellular matrix organization	Fibronectin	F1SS24	FN1	Sus scrofa (pig)
Metabolism of steroid hormones	Sulfatase N-terminal domain-containing protein	A0A287AGF2	STS	Sus scrofa (pig)
Interleukin-7 signaling	Bromodomain and WD repeat domain containing 1 Cytokine receptor-like factor 2 Histone H3 Histone H3 Insulin receptor substrate 1 Insulin receptor substrate 2 Interleukin 2 receptor gamma Interleukin-7 receptor subunit alpha Interleukin-7 Phosphatidylinositol 3-kinase regulatory subunit alpha isoform 2 Phosphatidylinositol 3-kinase regulatory subunit beta SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 Signal transducer and activator of transcription 3 Signal transducer and activator of transcription Signal transducer and activator of transcription Signal transducer and activator of transcription Tyrosine-protein kinase Tyrosine-protein kinase	A0A0A0MY60 A0A286ZJQ0 A0A286ZLI2 A0A286ZSF3 A0A287ARN1 A0A287B726 A0A2C9F3G4 E7CR01 F1RVA0 F1S916 F1SKR9 I3LLF1 K7GLC0 K7GSE8 K7GT64 Q19S50 Q76KD0 Q9N2G6	BRWD1 CRLF2 H3C12 H3C14 H3C15 H3C4 H3C6 HIST1H3E IL2RG IL7 IL7R IRS1 IRS2 JAK1 JAK3 LOC110257900 PIK3R1 PIK3R2 SMARCA4 STAT3 STAT5A STAT5B stat5B	Sus scrofa (pig)
Negative regulation of FGFR4 signaling	E3 ubiquitin-protein ligase CBL Fibroblast growth factor 23 Fibroblast growth factor 9 Fibroblast growth factor receptor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Growth factor receptor bound protein 2 Klotho beta Mitogen-activated protein kinase Mitogen-activated protein kinase Multifunctional fusion protein Polyubiquitin-C Tyrosine-protein phosphatase non-receptor type Ubiquitin B Ubiquitin C Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	A0A286ZQE1 A0A287AFX3 A0A287AXR0 A0A287AZA7 A0A287B3V5 A0A287BGK8 A0A2C9F3G2 A0A480LMF4 A0A480NH74 A0A5G2QUY7 A0A5G2R7G2 A0A5G2RG05 A7U5U2 B6E241 F1RM38 F1RY80 F1S3B8 F1S911 F1SET9 I3L560 I3LR27 P0CG68 Q95L12	CBL FGF1 FGF16 FGF18 FGF19 FGF2 FGF20 FGF23 FGF4 FGF6 FGF8 FGF9 FGFR4 Fgf4 GRB2 KLB MAPK1 MAPK3 PTPN11 RPS27A UBA52 UBB UBC	Sus scrofa (pig)
Interleukin-23 signaling	Interleukin 12 receptor subunit beta 1 Interleukin 23 receptor Interleukin-12 subunit beta Interleukin-23 subunit alpha Protein disulfide-isomerase Signal transducer and activator of transcription 3 Signal transducer and activator of transcription Signal transducer and activator of transcription Tyrosine-protein kinase JAK2 Tyrosine-protein kinase	A0A2C9F3G4 A0A5G2QAF8 A0A5G2R3H9 A0A5G2RDD7 E1U8C4 F1S3L9 O19064 Q19S50 Q28938 Q9N2H9	IL12B IL12RB1 IL23A IL23R JAK2 LOC100736717 P4HB SGRF STAT3 STAT4 TYK2 stat4	Sus scrofa (pig)
Lysosome Vesicle Biogenesis	ADP-ribosylation factor 1 AP complex subunit beta AP complex subunit beta AP complex subunit sigma AP complex subunit sigma AP-1 complex subunit gamma AP-1 complex subunit gamma AP-1 complex subunit mu-1 AP-1 complex subunit mu-2 AP-4 complex subunit mu-1 Adaptor related protein complex 4 subunit epsilon 1 Amyloid-beta A4 protein Amyloid-beta precursor protein Beta-arrestin-1 Charged multivesicular body protein 2a Clathrin heavy chain Clathrin light chain Clathrin light chain Clavesin-1 Deoxyribonuclease-2-alpha Deoxyribonuclease-2-alpha Hepatocyte growth factor-regulated tyrosine kinase substrate Mannose-6-phosphate receptor, cation dependent N-acetylglucosamine-6-sulfatase Thioredoxin domain containing 5 Vesicle-associated membrane protein 2 Vesicle-associated membrane protein 8 cathepsin X dynamin GTPase	A0A286ZND1 A0A286ZTE6 A0A287A524 A0A287A638 A0A287A682 A0A287A8E1 A0A287ARZ1 A0A287B610 A0A287B8X7 A0A287BFZ5 A0A5G2Q9Y0 A0A5G2QSL5 A0A5G2R276 A0A8W4F8A7 A0A8W4FA01 A0A8W4FAA6 A5GFX7 F1RFI2 F1RT89 F1RYM9 F1S3C7 F1SBR2 F1SDY3 F1SLX0 F1SS42 I3LE99 I3LSS2 O62855 P79307	A4 AD1 AP1B1 AP1G1 AP1G2 AP1M1 AP1M2 AP1S1 AP1S3 AP4B1 AP4E1 AP4M1 APP ARF1 ARRB1 CHMP2A CLTA CLTB CLTC CLVS1 CTSZ DNASE2 DNASE2A DNL2 DNM2 GNS HGS M6PR TXNDC5 VAMP2 VAMP8	Sus scrofa (pig)

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