GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	March 20, 2024
ECODAB	April 1, 2019

Displaying entries **26 - 50** of **360** in total

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Pathway Name	Protein Name	UniProt ID	Gene Symbol	Organism	GlyTouCan ID ▼
Lewis blood group biosynthesis	Alpha-(1,3)-fucosyltransferase Alpha-(1,3)-fucosyltransferase Alpha2,3-sialyltransferase CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 4 isoform 4 Fucosyltransferase Fucosyltransferase Fucosyltransferase Galactoside alpha-(1,2)-fucosyltransferase 2 Glycosyltransferase 2-like domain-containing protein Hexosyltransferase Hexosyltransferase Hexosyltransferase ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 6 Type 2 lactosamine alpha-2,3-sialyltransferase	A0A287AMU7 A0A287B633 A0A287B819 A0A287BIT3 A0A287BS10 A0A8W4FN42 F1RS05 F1RZT4 F1S6H2 F1SAB1 F1SBU3 I3L7N4 Q10982 Q70D54	B3GALT1 B3GALT2 B3GALT4 FUT10 FUT11 FUT2 FUT4 FUT7 LOC100513844 LOC110255214 ST3GAL-III ST3GAL3 ST3GAL4 ST3GAL6 ST6GALNAC6	Sus scrofa (pig)	G39211DH G81971FM G83633HB G90387AM G98173LG
Hyaluronan biosynthesis and export	ATP binding cassette subfamily C member 5 Cell migration inducing hyaluronidase 1 Hyaluronan synthase 2 hyaluronan synthase hyaluronan synthase	A0A287AY60 A0A5G2R512 A0A5G2RIV2 F1S290 Q75R37	ABCC5 CEMIP HAS1 HAS3 SHAS2 shas3	Sus scrofa (pig)	G35674CY
Hyaluronan uptake and degradation	Beta-glucuronidase Beta-hexosaminidase Beta-hexosaminidase CD44 antigen Hyaluronan mediated motility receptor Hyaluronidase Hyaluronidase Lymphatic vessel endothelial hyaluronan receptor 1 Sodium/hydrogen exchanger Stabilin 2	A0A287A7V3 A0A5G2RBP4 A0A5K1TZ96 D0G6X8 F1SGT4 F1SPN9 F1SRK1 F1STQ3 I3LTD0 Q4FAT7	CD44 GUSB HEXA HEXB HMMR HYAL1 HYAL2 LYVE1 SLC9A1 STAB2	Sus scrofa (pig)	G35674CY
Pentose phosphate pathway	6-phosphogluconate dehydrogenase, decarboxylating 6-phosphogluconolactonase Glucose-6-phosphate 1-dehydrogenase Phosphoglucomutase 2 Ribokinase Ribulose-phosphate 3-epimerase Sedoheptulokinase Transaldolase Transketolase deoxyribose-phosphate aldolase ribose-5-phosphate isomerase	A0A286ZQY9 A0A286ZS31 A0A287A7K4 A0A287BSL9 A0A5G2QMT1 A0A5G2QR34 A8U4R4 F1RLI9 F1S4K7 F1STC1 Q29593	DERA G6PD PGD PGLS PGM2 RBKS RPE RPIA SHPK TALDO1 TKT tkt	Sus scrofa (pig)	G31080DL
CS/DS degradation	Alpha-L-iduronidase Arylsulfatase B Beta-hexosaminidase Beta-hexosaminidase Biglycan Brevican core protein Chondroitin sulfate proteoglycan 4 Chondroitin sulfate proteoglycan 5 Decorin Hyaluronidase Iduronate 2-sulfatase Neurocan Versican core protein	A0A286ZRI8 A0A287A7V3 A0A287AHN9 A0A287AIY6 A0A287BS38 A0A5G2RB02 A0A5K1UKC5 A0A8W4FKJ8 D0G6X8 F1REZ2 F1SJ86 F1SPN9 M3VHA3	ARSB BCAN BGN CSPG4 CSPG5 DCN HEXA HEXB HYAL1 IDS IDUA NCAN VCAN	Sus scrofa (pig)	G27025MB
Glycosphingolipid catabolism	Alpha-galactosidase Arylsulfatase A Arylsulfatase B Arylsulfatase D Arylsulfatase E (chondrodysplasia punctata 1) Arylsulfatase G Arylsulfatase K Arylsulfatase family member I Arylsulfatase family member J Beta-galactosidase Beta-galactosidase Beta-galactosidase Beta-hexosaminidase Beta-hexosaminidase Carboxypeptidase Ectonucleotide pyrophosphatase/phosphodiesterase 7 Galactocerebrosidase Galactosidase beta 1 like Ganglioside GM2 activator Glucosylceramidase beta 3 Mannose-6-phosphate receptor, cation dependent Neutral ceramidase Non-lysosomal glucosylceramidase Prosaposin Sialidase-1 Sphingomyelin phosphodiesterase 4 Sphingomyelin phosphodiesterase Sulfatase N-terminal domain-containing protein Sulfatase N-terminal domain-containing protein Sulfatase N-terminal domain-containing protein Sulfatase modifying factor 1 Sulfatase modifying factor 2 ceramidase exo-alpha-sialidase exo-alpha-sialidase exo-alpha-sialidase sphingomyelin phosphodiesterase sphingomyelin phosphodiesterase	A0A286ZR19 A0A286ZRI8 A0A286ZTV6 A0A287A0M2 A0A287A7V3 A0A287AGF2 A0A287AXH1 A0A287B239 A0A287B636 A0A287BP79 A0A480LAY6 A0A480QKC9 A0A5G2Q9X4 A0A5G2QVV6 A0A5G2QXG4 A0A5G2QXL0 A0A5G2R907 A0A5G2R9H5 A5PF10 D0G6X8 F1REY9 F1RIU4 F1RK95 F1RL69 F1RMN6 F1RSY4 F1RZ75 F1S048 F1SDZ2 F1SES5 F1SLX0 F1SM45 F1SR82 F1STB6 I3LGI9 I3LM95 I3LRN8 I3LS26	ARSA ARSB ARSD ARSG ARSI ARSJ ARSK ARSL ASAH1 ASAH2 CTSA ENPP7 GALC GBA2 GBA3 GLA GLB1 GLB1L GLB1L2 GLB1L3 GM2A HEXA HEXB LOC100621771 M6PR NEU1 NEU2 NEU3 NEU4 PSAP SMPD1 SMPD2 SMPD3 SMPD4 STS SUMF1 SUMF2	Sus scrofa (pig)	G09546QO G27025MB G58161NS
Keratan sulfate degradation	Aggrecan core protein Beta-galactosidase Beta-galactosidase Beta-galactosidase Beta-hexosaminidase Beta-hexosaminidase Fibromodulin Galactosidase beta 1 like Keratocan Lumican Mimecan N-acetylglucosamine-6-sulfatase Osteomodulin Prolargin	A0A0H5ANC0 A0A287A524 A0A287A7V3 A0A287B239 A0A287B863 A0A5G2R907 D0G6X8 F1S6B4 F1S6B5 F1SQ08 F1SQ09 F1SR82 F1SUE2 I3LGI9	ACAN FMOD GLB1 GLB1L GLB1L2 GLB1L3 GNS HEXA HEXB KERA LUM OGN OMD PRELP	Sus scrofa (pig)	G09546QO G20239CJ G27025MB G50451AA G80016QC G82768YB G85384LV
N-glycan trimming in the ER and Calnexin/Calreticulin cycle	26S protease regulatory subunit 4 Autocrine motility factor receptor Peptide-N(4)-(N-acetyl-beta-glucosaminyl)asparagine amidase Polyubiquitin-C UBX domain protein 1 Ubiquitin B Ubiquitin C Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase	A0A287AZA7 A0A2C9F3G2 A0A480HSN1 A0A5G2QHB2 A7U5U2 F1RF19 F1RS44 F1S911 F2Z5J1 P0CG68	AMFR ENGASE NGLY1 PSMC1 RPS27A UBA52 UBB UBC UBXN1	Sus scrofa (pig)	G03934XO G25577BM G28233ME G51034LA G86419OL
HS-GAG degradation	Agrin Alpha-L-iduronidase Beta-galactosidase Beta-galactosidase Beta-galactosidase Beta-glucuronidase Galactosidase beta 1 like Glypican 2 Glypican 4 Glypican 5 Glypican-1 Glypican-3 Glypican-6 Heparanase 2 (inactive) Heparanase Iduronate 2-sulfatase N-acetyl-alpha-glucosaminidase N-sulfoglucosamine sulfohydrolase Syndecan-4 Syndecan Syndecan Syndecan	A0A286ZS39 A0A287AJ15 A0A287ATH4 A0A287B239 A0A287B286 A0A287BS38 A0A480K0L3 A0A5G2QG63 A0A5G2QHV1 A0A5G2R907 F1RNM8 F1RTE1 F1RZ89 F1S0L5 F1S8W7 F1SR82 I3LGI9 K7GNF5 K7GQ93 M3VHA3 Q4FAT7 Q8HZJ6	AGRN GLB1 GLB1L GLB1L2 GLB1L3 GPC1 GPC2 GPC3 GPC4 GPC5 GPC6 GUSB HPSE HPSE2 IDS IDUA NAGLU SDC1 SDC2 SDC3 SDC4 SGSH	Sus scrofa (pig)	G01550VL G09546QO
Lysosomal oligosaccharide catabolism	Alpha-mannosidase Alpha-mannosidase Beta-mannosidase alpha-mannosidase	A0A287AZU8 A0A5G2R0E8 F1S106 I3LHM6	MAN2B1 MAN2B2 MAN2C1 MANBA	Sus scrofa (pig)	G00027MO G25577BM G28233ME G70323CJ G90333CG
Aflatoxin activation and detoxification	Aflatoxin B1 aldehyde reductase member 4 Aminoacylase-1 Cytochrome P450 1A Cytochrome P450 3A Cytochrome P450 3A Cytochrome P450 3A Cytochrome P450 Dipeptidase 1 Dipeptidase 3 Dipeptidase Dipeptidase Gamma-glutamyltransferase 6 Glutathione hydrolase Glutathione hydrolase Microsomal glutathione S-transferase 1 Microsomal glutathione S-transferase 2 Microsomal glutathione S-transferase 3	A0A0K1TQQ0 A0A287B7I8 A0A5G2R0Q5 A0A5K1UGB8 F1S4Y1 F1SJ26 F1SUP1 I3L719 I3LA57 I3LBY7 I3LEX8 I3LFR7 P22412 P37111 P79382 Q2EN77 Q8SQ68	ACY1 AKR7A2 CYP1A2 CYP2A19 CYP3A22 CYP3A227 CYP3A29 DPEP1 DPEP2 DPEP3 GGT1 GGT6 GGT7 GST12 MGST1 MGST2 MGST3 RDP	Sus scrofa (pig)
Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors	DEK proto-onco Transcription factor AP-2-alpha	A0A287B9K7 A0A5G2QII0	DEK TFAP2A	Sus scrofa (pig)
RAC1 GTPase cycle	Abl interactor 1 Abl interactor 2 Active breakpoint cluster region-related protein Adhesion molecule with Ig like domain 2 Alsin Rho guanine nucleotide exchange factor ALS2 Amino acid transporter Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2 BAR/IMD domain containing adaptor protein 2 like 1 BCR activator of RhoGEF and GTPase BRICK1 subunit of SCAR/WAVE actin nucleating complex Brain-specific angiogenesis inhibitor 1-associated protein 2 CDC42 effector protein 1 CDC42 effector protein 4 Caveolin Cell division control protein 42 homolog Chimaerin Chimerin 2 Citron Rho-interacting kinase Cytochrome b-245 heavy chain Cytochrome b-245 light chain Cytoplasmic FMR1 interacting protein 1 Cytoplasmic FMR1-interacting protein DEF6 guanine nucleotide exchange factor DEP domain containing 1B Dedicator of cytokinesis 10 Dedicator of cytokinesis 11 Dedicator of cytokinesis 1 Dedicator of cytokinesis 2 Dedicator of cytokinesis 3 Dedicator of cytokinesis 4 Dedicator of cytokinesis 5 Dedicator of cytokinesis 6 Dedicator of cytokinesis 7 Dedicator of cytokinesis 8 Dedicator of cytokinesis 9 Delta(14)-sterol reductase LBR Delta-like protein Diaphanous related formin 3 Emerin Epithelial cell transforming 2 Extended synaptotagmin 1 FERM domain containing kindlin 2 FERM, ARH/RhoGEF and pleckstrin domain protein 2 FERM, ARHGEF and pleckstrin domain-containing protein 1 FYVE, RhoGEF and PH domain containing 5 Family with sequence similarity 13 member A Family with sequence similarity 13 member B Formin like 1 G protein subunit alpha 13 GEM interacting protein GIT ArfGAP 1 GIT ArfGAP 2 Granule associated Rac and RHOG effector 1 Guanine nucleotide exchange factor DBS isoform X2 IQ motif containing GTPase activating protein 2 IQ motif containing GTPase activating protein 3 Integrin beta Kinectin 1 MAGUK p55 subfamily member 7 MCF.2 cell line derived transforming sequence Melanoma cell adhesion molecule Myosin IXB NADPH oxidase 1 NADPH oxidase 3 NADPH oxidase activator 1 NADPH oxidase organizer 1 NCK associated protein 1 like NHS actin remodeling regulator Nck-associated protein 1 Neuronal guanine nucleotide exchange factor Neutrophil cytosolic factor 1 Neutrophil cytosolic factor 2 Neutrophil cytosolic factor 4 Nischarin Oligophrenin-1 Par-6 family cell polarity regulator alpha Phosphatidylinositol 3-kinase regulatory subunit alpha isoform 2 Phosphatidylinositol 3-kinase regulatory subunit beta Phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 1 Phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 2 Phospholipase Phospholipase Pleckstrin homology and RhoGEF domain containing G1 Pleckstrin homology and RhoGEF domain containing G2 Pleckstrin homology and RhoGEF domain containing G3 Pleckstrin homology and RhoGEF domain containing G6 Proto-oncogene vav RNA binding motif protein 39 Rac GTPase activating protein 1 Rac/Cdc42 guanine nucleotide exchange factor 6 Ragulator complex protein LAMTOR1 Ras protein specific guanine nucleotide releasing factor 2 Ras-related C3 botulinum toxin substrate 1 Ras-related protein Rab-7a Rho GDP-dissociation inhibitor 1 Rho GTPase activating protein 12 Rho GTPase activating protein 17 Rho GTPase activating protein 1 Rho GTPase activating protein 20 Rho GTPase activating protein 21 Rho GTPase activating protein 22 Rho GTPase activating protein 23 Rho GTPase activating protein 24 Rho GTPase activating protein 25 Rho GTPase activating protein 27 Rho GTPase activating protein 30 Rho GTPase activating protein 31 Rho GTPase activating protein 33 Rho GTPase activating protein 39 Rho GTPase activating protein 44 Rho GTPase activating protein 45 Rho GTPase activating protein 4 Rho GTPase activating protein 5 Rho GTPase activating protein 9 Rho GTPase-activating protein 10 Rho GTPase-activating protein 15 Rho GTPase-activating protein 26 Rho GTPase-activating protein 29 Rho GTPase-activating protein 35 Rho GTPase-activating protein 7 Rho guanine nucleotide exchange factor 10 Rho guanine nucleotide exchange factor 11 Rho guanine nucleotide exchange factor 15 Rho guanine nucleotide exchange factor 19 Rho guanine nucleotide exchange factor 25 Rho guanine nucleotide exchange factor 39 Rho guanine nucleotide exchange factor 5 Rho guanine nucleotide exchange factor 7 Rho/Rac guanine nucleotide exchange factor 18 SH3 domain binding protein 1 SLIT-ROBO Rho GTPase activating protein 1 SLIT-ROBO Rho GTPase activating protein 2 SLIT-ROBO Rho GTPase activating protein 3 SOS Ras/Rac guanine nucleotide exchange factor 1 SOS Ras/Rho guanine nucleotide exchange factor 2 Switching B cell complex subunit SWAP70 Synapse defective Rho GTPase homolog 2 Synaptosomal-associated protein T cell activation RhoGTPase activating protein TIAM Rac1 associated GEF 1 TIAM Rac1 associated GEF 2 Transferrin receptor protein 1 Transferrin receptor protein 1 Tyrosine-protein kinase Vang-like protein Vav guanine nucleotide exchange factor 2 Vesicle-associated membrane protein 3 WASP like actin nucleation promoting factor WH2 domain-containing protein Wiskott-Aldrich syndrome protein family member Wiskott-Aldrich syndrome protein family member YKT6 v-SNARE homolog non-specific serine/threonine protein kinase non-specific serine/threonine protein kinase non-specific serine/threonine protein kinase non-specific serine/threonine protein kinase non-specific serine/threonine protein kinase non-specific serine/threonine protein kinase phosphatidylinositol-4,5-bisphosphate 3-kinase protein kinase C protein kinase C receptor protein-tyrosine kinase	A0A0U2ETD0 A0A286ZI16 A0A286ZJI5 A0A286ZJP1 A0A286ZJQ9 A0A286ZLF6 A0A286ZMP2 A0A286ZN71 A0A286ZPM4 A0A286ZQX2 A0A286ZUE0 A0A286ZUQ0 A0A286ZWQ0 A0A286ZYD7 A0A286ZZ01 A0A286ZZA8 A0A286ZZD3 A0A287A159 A0A287A1S5 A0A287A2E5 A0A287A2N5 A0A287A5N4 A0A287A671 A0A287A853 A0A287AAT1 A0A287AFT4 A0A287AGS3 A0A287AH65 A0A287AHK8 A0A287AIC4 A0A287AIM9 A0A287AJY4 A0A287AKJ4 A0A287AMB8 A0A287APY3 A0A287AR23 A0A287ART1 A0A287AUX3 A0A287AV01 A0A287AV22 A0A287AVV3 A0A287AVY9 A0A287AYN9 A0A287AZB9 A0A287AZG0 A0A287B3E0 A0A287B6K8 A0A287B8N4 A0A287B9E3 A0A287BAQ0 A0A287BEC7 A0A287BEY0 A0A287BG06 A0A287BGM7 A0A287BKM4 A0A287BKW5 A0A287BKX8 A0A287BLK5 A0A287BPH9 A0A287BRV9 A0A287BSE0 A0A287BSS5 A0A287BT14 A0A287BT99 A0A480IRR7 A0A480KQN9 A0A480LCB3 A0A480P3R5 A0A481A732 A0A5G2QA45 A0A5G2QJL5 A0A5G2QPS5 A0A5G2QQG7 A0A5G2QVJ5 A0A5G2QWD7 A0A5G2QXS5 A0A5G2R098 A0A5G2R0L8 A0A5G2R1A0 A0A5G2R4C3 A0A5G2R5Z3 A0A5G2RDC7 A0A5G2RET7 A0A5G2RKR1 A0A5K1UB41 A0A5K1VSC0 A0A5K1VSS6 A0A5S6GXI4 A0A8W4FEI6 A0A8W4FG77 A0A8W4FI56 A0A8W4FJM1 A0A8W4FMP1 A0A8W4FMS3 A0A8W4FNZ4 A0A8W4FQ33 E7EI20 F1RF08 F1RFK7 F1RFV6 F1RFZ2 F1RJ64 F1RJL1 F1RJU3 F1RM07 F1RM08 F1RN87 F1RQ74 F1RR27 F1RS73 F1RSQ1 F1RTK2 F1RTW7 F1RU77 F1RV35 F1RW15 F1RZ09 F1S291 F1S4M1 F1S540 F1S916 F1SAW7 F1SB25 F1SB58 F1SEG8 F1SEU3 F1SEW6 F1SG02 F1SGW7 F1SH88 F1SHY0 F1SKH5 F1SKH7 F1SKR9 F1SMK2 F1SNP7 F1SPI5 F1SPM2 F1SQW0 F1SRN4 F1SSN5 F1SUS7 F1SUT8 F2Z5S6 I3L5H9 I3L6P2 I3LBU6 I3LCC0 I3LD06 I3LDR4 I3LG66 I3LIY8 I3LKJ5 I3LKY7 I3LPE0 I3LQ81 K7GKS3 K7GQ83 K7GR14 K9IWB5 K9J6I8 M3VH35 Q007T2 Q8HZV3	ABI1 ABI2 ABL2 ABR ALS2 AMIGO2 ARAP1 ARAP2 ARAP3 ARHGAP1 ARHGAP10 ARHGAP12 ARHGAP15 ARHGAP17 ARHGAP20 ARHGAP21 ARHGAP22 ARHGAP23 ARHGAP24 ARHGAP25 ARHGAP26 ARHGAP27 ARHGAP29 ARHGAP30 ARHGAP31 ARHGAP33 ARHGAP35 ARHGAP39 ARHGAP4 ARHGAP44 ARHGAP45 ARHGAP5 ARHGAP9 ARHGDIA ARHGEF10 ARHGEF11 ARHGEF15 ARHGEF18 ARHGEF19 ARHGEF25 ARHGEF39 ARHGEF5 ARHGEF6 ARHGEF7 BAIAP2 BAIAP2L1 BCR BRK1 CAV1 CDC42 CDC42BPA CDC42EP1 CDC42EP4 CHN1 CHN2 CIT CYBA CYFIP1 CYFIP2 DEF6 DEPDC1B DIAPH3 DLC1 DOCK1 DOCK10 DOCK11 DOCK2 DOCK3 DOCK4 DOCK5 DOCK6 DOCK7 DOCK8 DOCK9 ECT2 EMD EPHA2 ESYT1 FAM13A FAM13B FARP1 FARP2 FERMT2 FGD5 FMNL1 GARRE1 GIT1 GIT2 GMIP GNA13 GP91-PHOX IQGAP2 IQGAP3 ITGB1 JAG1 KIAA0355 KTN1 LAMTOR1 LBR MCAM MCF2 MCF2L MPP7 MYO9B NCF1 NCF2 NCF4 NCKAP1 NCKAP1L NGEF NHS NISCH NOX1 NOX3 NOXA1 NOXO1 OPHN1 PAK1 PAK2 PAK5 PAK6 PARD6A PIK3CA PIK3R1 PIK3R2 PKN1 PKN2 PLD1 PLD2 PLEKHG1 PLEKHG2 PLEKHG3 PLEKHG6 PREX1 PREX2 RAB7A RAC1 RACGAP1 RASGRF2 RBM39 SH3BP1 SLC1A5 SNAP23 SOS1 SOS2 SRGAP1 SRGAP2 SRGAP3 SWAP70 SYDE2 TAGAP TFRC TIAM1 TIAM2 TRIO VAMP3 VANGL1 VAV1 VAV2 WASF2 WASF3 WASL WIPF1 YKT6	Sus scrofa (pig)
MET activates PTK2 signaling	Hepatocyte growth factor receptor Hepatocyte growth factor Tyrosine-protein kinase	F1SB93 K7GPR7 Q2QLE0	HGF MET SRC	Sus scrofa (pig)
NTRK2 activates RAC1	Brain-derived neurotrophic factor Dedicator of cytokinesis 3 Ras-related C3 botulinum toxin substrate 1 Tyrosine-protein kinase Fyn	A0A287AKJ4 A0A8W4FI56 A1Y2K1 P14082	BDNF DOCK3 FYN RAC1	Sus scrofa (pig)
RND3 GTPase cycle	BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 1 BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 2 Carboxypeptidase D Caveolin Coiled-coil domain containing 88A Creatine kinase B-type Cytoskeleton associated protein 4 DEP domain containing 1B Desmoglein 1 Desmoglein-1 Desmoplakin Discs large MAGUK scaffold protein 5 Dystonin Family with sequence similarity 83 member B Flotillin Kinectin 1 Mucin 13, cell surface associated Nischarin Phosphatidylinositol 3-kinase regulatory subunit alpha isoform 2 Phosphatidylinositol 3-kinase regulatory subunit beta Phosphatidylinositol binding clathrin assembly protein Plakophilin 4 Pleckstrin homology and RhoGEF domain containing G5 RAS protein activator like 2 RNA binding motif protein 39 Rho GTPase activating protein 21 Rho GTPase activating protein 5 Rho GTPase-activating protein 35 Rho-associated protein kinase Rho-related GTP-binding protein RhoE Scribble planar cell polarity protein Ssemaphorin 4F Thioredoxin like 1 Tropomodulin 3 Tyrosine-protein phosphatase non-receptor type 13 UBX domain protein 11 Uncharacterized protein Vang-like protein Vang-like protein receptor protein-tyrosine kinase tRNA (34-2'-O)-methyltransferase regulator WDR6	A0A286ZJQ9 A0A286ZM17 A0A286ZPP2 A0A287AH84 A0A287AIV8 A0A287ALN0 A0A287B402 A0A287B7U3 A0A287BAQ0 A0A287BCT3 A0A287BKB6 A0A287BQA2 A0A287BS05 A0A480JZF5 A0A5G2QA45 A0A5G2QIS7 A0A5G2R425 A0A5G2R4N6 A0A5G2RAI6 A0A5G2RKR1 A0A8W4FAC1 F1RJY3 F1RM07 F1RN68 F1RW75 F1RZW2 F1S1X9 F1S916 F1SAW7 F1SKR9 F1SPP8 F1SQ58 F1SSN5 F1SUT8 I3LA65 I3LD06 I3LDR4 I3LM60 I3LMD8 I3LPB5 Q3BDI7	ARHGAP21 ARHGAP35 ARHGAP5 CAV1 CCDC88A CKAP4 CKB CPD DEPDC1B DLG5 DSG1 DSP DST EPHA2 FAM83B FLOT2 KCTD13 KTN1 LOC100516390 MUC13 NISCH PICALM PIK3R1 PIK3R2 PKP4 PLEKHG5 PTPN13 RASAL2 RBM39 RND3 ROCK1 SCRIB SEMA4F TMOD3 TNFAIP1 TXNL1 UBXN11 VANGL1 VANGL2 WDR6	Sus scrofa (pig)
Atorvastatin ADME	ABC-type glutathione-S-conjugate transporter Cytochrome P450 3A Cytochrome P450 3A Cytochrome P450 3A Multidrug resistance protein 1 Paraoxonase Paraoxonase Solute carrier organic anion transporter family member Solute carrier organic anion transporter family member glucuronosyltransferase	A0A287AWR7 A0A287B7I8 A0A8W4FMT0 F1S8V9 F1SBZ0 F1SM17 F1SUN1 F6KQD9 I3LA57 I3LEX8	ABCC2 CYP3A22 CYP3A227 CYP3A29 LOC100522267 PON1 PON3 SLCO1B2 SLCO1B3 SLCO2B1 UGT1A6	Sus scrofa (pig)
TNF signaling	ADAM metallopeptidase domain 17 BAG cochaperone 4 Receptor interacting serine/threonine kinase 1 TNF receptor-associated factor Tumor necrosis factor receptor superfamily member 1A Tumor necrosis factor receptor type 1-associated DEATH domain protein Tumor necrosis factor	A0A286ZVH7 A0A287AP23 A0A287BPE4 A0A287BRT1 A0A5G2QLA4 F1RVZ4 P23563	ADAM17 BAG4 RIPK1 TNF TNFA TNFRSF1A TNFSF2 TRADD TRAF2	Sus scrofa (pig)
Growth hormone receptor signaling	Growth hormone 1 Mitogen-activated protein kinase Mitogen-activated protein kinase Prolactin receptor Prolactin SH2B adaptor protein 1 Somatotropin Tyrosine-protein kinase JAK2 Tyrosine-protein kinase Tyrosine-protein phosphatase non-receptor type	A0A287BAQ6 A0A480NH74 A0A5G2RG05 A0A5S6I4D7 F1RFI0 F1RT53 O19064 P01238 P01248 Q6JTA8	GH1 JAK2 LYN MAPK1 MAPK3 PRL PRLR PTPN1 SH2B1	Sus scrofa (pig)
Estrogen-dependent gene expression	CDK9 Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 1 Core-binding factor subunit beta Cyclin-T1 DNA-directed RNA polymerase II subunit E DNA-directed RNA polymerase II subunit RPB9 DNA-directed RNA polymerase RBP11-like dimerisation domain-containing protein DNA-directed RNA polymerase subunit beta DNA-directed RNA polymerase subunit DNA-directed RNA polymerase subunit DNA-directed RNA polymerases I, II, and III subunit RPABC3 DNA-directed RNA polymerases I, II, and III subunit RPABC5 Estrogen receptor Forkhead box A1 GATA binding protein 3 Growth regulating estrogen receptor binding 1 Heat shock protein HSP 90-alpha Heat shock protein HSP 90-alpha Heat shock protein HSP 90-beta Histone H2A Histone H2A Histone H2A Histone H2A Histone H2A Histone H2A Histone H2A Histone H2A Histone H2A Histone H2B Histone H2B Histone H2B Histone H2B Histone H2B Histone H3.3 Histone H3 Histone H3 Histone H4 Histone acetyltransferase Histone acetyltransferase Histone deacetylase 1 Histone-arginine methyltransferase CARM1 Lysine-specific histone demethylase Mediator of RNA polymerase II transcription subunit 1 Nuclear receptor coactivator 3 Nuclear receptor coactivator Nuclear receptor coactivator Nuclear receptor interacting protein 1 Nuclear receptor subfamily 5 group A member 2 POU domain protein Probable ATP-dependent RNA helicase DDX5 Progesterone receptor Prostaglandin E synthase 3 Protein c-Fos RNA polymerase II subunit D Ral transcription factor IIA subunit 1 Receptor protein-tyrosine kinase Runt-related transcription factor Sp1 transcription factor TLE family member 3, transcriptional corepressor Transcription factor Jun Transcription initiation factor IIA subunit 2 Transcription initiation factor IIF subunit alpha Upstream stimulatory factor 1 Upstream transcription factor 2, c-fos interacting YY1 transcription factor Zinc finger protein 217 [histone H3]-trimethyl-L-lysine(9) demethylase histone acetyltransferase histone acetyltransferase peptidylprolyl isomerase type I protein arginine methyltransferase	A0A286ZJQ0 A0A286ZKC5 A0A286ZQB6 A0A286ZZJ6 A0A287A670 A0A287ADR4 A0A287AEQ3 A0A287ALJ7 A0A287AVZ1 A0A287BCG5 A0A287BID4 A0A287BIM6 A0A287BJI0 A0A287BKD1 A0A287BLH5 A0A287BTE0 A0A480JJE7 A0A480PU90 A0A480SJY5 A0A5G2QMX0 A0A5G2QRV8 A0A5G2QTZ9 A0A5G2QVN7 A0A5G2QW64 A0A5G2R2L4 A0A5G2R318 A0A5G2R6C5 A0A5G2RF15 A0A5G2RHQ3 A0A8I8C3K7 A0A8W4F948 A0A8W4F9W9 A0A8W4FA99 A0A8W4FCQ5 A0A8W4FIU6 A0A8W4FNL8 A5GFZ7 C9E1C9 F1RK46 F1RRK4 F1RU09 F1RUM8 F1RVA0 F1RWL2 F1SBF0 F1SBT5 F1SE01 F1SIT5 F1SL99 F1SSQ9 F1STX7 F1SV76 F2Z584 F2Z587 F2Z5L2 F2Z5L5 F8SIP5 I3L9U8 I3LBN0 I3LCK3 I3LCU3 I3LGP4 I3LJR4 I3LP18 I3LRW1 K9IVK7 O02705 P60899 P62802 Q29040 Q71LE2	CARM1 CBFB CCNT1 CDK9 CITED1 CREBBP DDX5 EP300 ERBB4 ESR ESR1 FKBP4 FOS FOXA1 GATA3 GREB1 GTF2A1 GTF2A2 GTF2F1 H1-2 H2AB1 H2AB2 H2AB3 H2AC10 H2AC11 H2AC17 H2AC18 H2AC19 H2AC20 H2AC4 H2AC6 H2AC7 H2AC8 H2AX H2AZ2 H2BC11 H2BC12 H2BC19 H2BC20 H2BC21 H2BC5 H3-3A H3C12 H3C14 H3C15 H3C4 H3C6 H3F3A HDAC1 HIST1H2BD HIST1H3E HSP90A HSP90AA1 HSP90AB1 HSPCA JUN KAT2B KAT5 KDM1A KDM4B LOC110261482 MED1 NCOA1 NCOA2 NCOA3 NR3A1 NR5A2 NRIP1 PGR POLR2A POLR2B POLR2D POLR2E POLR2G POLR2H POLR2I POLR2J POLR2L POU2F1 PRMT1 PTGES3 RUNX1 SP1 TLE3 USF1 USF2 YY1 ZNF217	Sus scrofa (pig)
ABO blood group biosynthesis	Galactoside alpha-(1,2)-fucosyltransferase 1 Galactoside alpha-(1,2)-fucosyltransferase 2	Q10982 Q29043	FUT1 FUT2	Sus scrofa (pig)
Cytosolic sulfonation of small molecules	3'(2'),5'-bisphosphate nucleotidase 1 Golgi-resident adenosine 3',5'-bisphosphate 3'-phosphatase Podocalyxin like 2 Protein-tyrosine sulfotransferase Putative protein-lysine deacylase ABHD14B Sulfotransferase Sulfotransferase Sulfotransferase Sulfotransferase Sulfotransferase Sulfotransferase Sulfotransferase Sulfotransferase	A0A286ZRJ8 A0A286ZW98 A0A287A5T1 A0A287ADU1 A0A287BHE6 F1RT67 F1S9K3 F1SJU2 I3L7V6 I3LC84 I3LLX8 I3LRP8 Q3S3F7	ABHD14B BPNT1 BPNT2 IMPA3 IMPAD1 PODXL2 SULT1A3 SULT1B1 SULT1C4 SULT1E1 SULT2A1 SULT2B1 SULT4A1 SULT6B1 TPST2	Sus scrofa (pig)
Insulin receptor signalling cascade	Growth factor receptor bound protein 2 Growth factor receptor-bound protein 10 Insulin SHC-transforming protein 1 SOS Ras/Rac guanine nucleotide exchange factor 1 Tyrosine-protein kinase receptor	A0A286ZUQ0 A0A5K1V5Y3 B5KFD7 B6E241 F1SCL0 P01315	GRB2 Grb10 INS INSR SHC1 SOS1	Sus scrofa (pig)
PI3K events in ERBB4 signaling	Betacellulin Epiregulin Neuregulin 2 Neuregulin 3 Phosphatidylinositol 3-kinase regulatory subunit alpha isoform 2 Pro-neuregulin-1, membrane-bound isoform Proheparin-binding EGF-like growth factor Receptor protein-tyrosine kinase phosphatidylinositol-4,5-bisphosphate 3-kinase	A0A286ZJM1 A0A287A6I2 A0A287AZM9 A0A287BCW9 A0A5G2R1H6 A0A5K1UB41 F1SKR9 F1SSQ9 Q01580	BTC DTR ERBB4 EREG HBEGF HEGFL NRG1 NRG2 NRG3 PIK3CA PIK3R1	Sus scrofa (pig)
Negative regulation of the PI3K/AKT network	Phosphatase and tensin homolog	F2Z5H1	PTEN	Sus scrofa (pig)

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