GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	March 20, 2024
ECODAB	April 1, 2019

Displaying entries **51 - 75** of **360** in total

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Pathway Name	Protein Name ▼	UniProt ID	Gene Symbol	Organism	GlyTouCan ID
DDX58/IFIH1-mediated induction of interferon-alpha/beta	Heat shock protein HSP 90-alpha Heat shock protein HSP 90-alpha Heat shock protein HSP 90-beta Interferon regulatory factor 3 Mitochondrial antiviral signaling protein Mitochondrial import receptor subunit TOM70 TANK binding kinase 1	A0A286ZKC5 A0A287AL42 A0A480UKD4 A0A5K1V3V4 A0A8I8C3K7 K7GM32 O02705	HSP90A HSP90AA1 HSP90AB1 HSPCA IRF3 MAVS TBK1 TOMM70	Sus scrofa (pig)
MET Receptor Activation	HGF activator Hepatocyte growth factor receptor Hepatocyte growth factor Hepsin Serine peptidase inhibitor, Kunitz type 1 Serine peptidase inhibitor, Kunitz type 2	A0A286ZMW3 A0A287BCY0 A0A287BHH9 A0A5G2R148 F1SB93 Q2QLE0	HGF HGFAC HPN MET SPINT1 SPINT2	Sus scrofa (pig)
Growth hormone receptor signaling	Growth hormone 1 Mitogen-activated protein kinase Mitogen-activated protein kinase Prolactin receptor Prolactin SH2B adaptor protein 1 Somatotropin Tyrosine-protein kinase JAK2 Tyrosine-protein kinase Tyrosine-protein phosphatase non-receptor type	A0A287BAQ6 A0A480NH74 A0A5G2RG05 A0A5S6I4D7 F1RFI0 F1RT53 O19064 P01238 P01248 Q6JTA8	GH1 JAK2 LYN MAPK1 MAPK3 PRL PRLR PTPN1 SH2B1	Sus scrofa (pig)
SHC-related events triggered by IGF1R	Growth factor receptor bound protein 2 Insulin-like growth factor I Insulin-like growth factor II Insulin-like growth factor II SHC-transforming protein 1 SOS Ras/Rac guanine nucleotide exchange factor 1 Tyrosine-protein kinase receptor	A0A286ZUQ0 A0A287BJL7 A0A5K1V5Y3 B6E241 F1CK17 P16545 P23695	GRB2 IGF1 IGF1R IGF2 SHC1 SOS1	Sus scrofa (pig)
Insulin receptor signalling cascade	Growth factor receptor bound protein 2 Growth factor receptor-bound protein 10 Insulin SHC-transforming protein 1 SOS Ras/Rac guanine nucleotide exchange factor 1 Tyrosine-protein kinase receptor	A0A286ZUQ0 A0A5K1V5Y3 B5KFD7 B6E241 F1SCL0 P01315	GRB2 Grb10 INS INSR SHC1 SOS1	Sus scrofa (pig)
PTK6 promotes HIF1A stabilization	Glycoprotein nmb Hypoxia-inducible factor 1-alpha Proheparin-binding EGF-like growth factor Receptor protein-tyrosine kinase Tyrosine-protein kinase non-specific serine/threonine protein kinase	A0A286ZJF6 A0A286ZYS4 A0A287B2Q0 A0A5G2QBP1 F1SHN7 Q01580	DTR EGFR GPNMB HBEGF HEGFL HIF1A LRRK2 PTK6	Sus scrofa (pig)
Platelet Aggregation (Plug Formation)	Glycoprotein IX platelet Glycoprotein Ib platelet subunit beta Glycoprotein V platelet Prothrombin von Willebrand factor	B7TY21 B7TY22 F1SIB1 F1SL22 K7GN20	F2 GP1BB GP5 GP9 GPIX GPIbB VWF	Sus scrofa (pig)
Glycerophospholipid catabolism	Glycerophosphocholine cholinephosphodiesterase ENPP6 Glycerophosphodiester phosphodiesterase 1 Patatin like phospholipase domain containing 6	A0A286ZW95 I3LLY2 Q58D68	ENPP6 GDE1 PNPLA6	Sus scrofa (pig)
Electric Transmission Across Gap Junctions	Gap junction gamma-1 protein Gap junction protein Gap junction protein Pannexin Pannexin	A0A287AL56 A0A287B8K3 A4GVD1 F1RXR8 F1RY20	GJA10 GJA7 GJC1 GJD2 PANX PANX1 PANX2	Sus scrofa (pig)
ABO blood group biosynthesis	Galactoside alpha-(1,2)-fucosyltransferase 1 Galactoside alpha-(1,2)-fucosyltransferase 2	Q10982 Q29043	FUT1 FUT2	Sus scrofa (pig)
Galactose catabolism	Galactose-1-phosphate uridylyltransferase galactokinase	A0A5G2QDU1 F1S3U0	GALK1 GALT	Sus scrofa (pig)	G93924TT
EGFR Transactivation by Gastrin	GTPase HRas GTPase NRas Growth factor receptor bound protein 2 Proheparin-binding EGF-like growth factor Protein kinase C Receptor protein-tyrosine kinase SOS Ras/Rac guanine nucleotide exchange factor 1 Stromelysin-1 small monomeric GTPase	A0A286ZUQ0 A0A5G2QBP1 A0A5G2QLX0 B6E241 F1RV14 F1SV58 I3LCQ9 Q01580 Q2MJK3	DTR EGFR GRB2 HBEGF HEGFL HRAS KRAS MMP3 NRAS PRKCA SOS1	Sus scrofa (pig)
MET activates RAS signaling	GTPase HRas GTPase NRas Growth factor receptor bound protein 2 Hepatocyte growth factor receptor Hepatocyte growth factor Mucin 20, cell surface associated RAN binding protein 10 Ran-binding protein 9 SHC-transforming protein 1 SOS Ras/Rac guanine nucleotide exchange factor 1 small monomeric GTPase	A0A286ZUQ0 A0A5G2QLX0 A0A5K1V5Y3 B6E241 F1RV77 F1SB93 F6Q8N2 I3LCC3 I3LCQ9 Q2MJK3 Q2QLE0	GRB2 HGF HRAS KRAS MET MUC20 NRAS RANBP10 RANBP9 SHC1 SOS1	Sus scrofa (pig)
MET activates PTPN11	GRB2 associated binding protein 1 Growth factor receptor bound protein 2 Hepatocyte growth factor receptor Hepatocyte growth factor Tyrosine-protein phosphatase non-receptor type	A0A480LMF4 B6E241 F1SB93 K7GMT0 Q2QLE0	GAB1 GRB2 HGF MET PTPN11	Sus scrofa (pig)
MET activates PI3K/AKT signaling	GRB2 associated binding protein 1 Growth factor receptor bound protein 2 Hepatocyte growth factor receptor Hepatocyte growth factor Phosphatidylinositol 3-kinase regulatory subunit alpha isoform 2 phosphatidylinositol-4,5-bisphosphate 3-kinase	A0A5K1UB41 B6E241 F1SB93 F1SKR9 K7GMT0 Q2QLE0	GAB1 GRB2 HGF MET PIK3CA PIK3R1	Sus scrofa (pig)
Amine ligand-binding receptors	G-protein coupled receptor 143 G-protein coupled receptor 143	A0A286ZZS9 F1SG22	GPR143	Sus scrofa (pig)
Sensory perception of sweet, bitter, and umami (glutamate) taste	G protein subunit beta 3 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 Inositol 1,4,5-trisphosphate receptor Taste 1 receptor member 1 Taste 2 receptor member 39 Taste receptor type 1 member 2 Taste receptor type 1 member 3 Taste receptor type 2 member 40 Taste receptor type 2 Taste receptor type 2 Taste receptor type 2 Taste receptor type 2 Taste receptor type 2 Taste receptor type 2 Taste receptor type 2 Taste receptor type 2 Taste receptor type 2	A0A286ZVQ9 A0A287A3Q1 A0A287AA31 A0A287AFV6 A0A287AW90 A0A287AYK0 A0A287BL11 A0A480JCU5 A0A5G2QX37 A0A8W4F831 F1RIJ7 F1RJE6 F1SLU8 F1SSI6 I3LCT3 I3LE78 I3LF46	GNB1 GNB3 ITPR3 LOC100154902 TAS1R1 TAS1R2 TAS1R3 TAS2R1 TAS2R10 TAS2R16 TAS2R3 TAS2R39 TAS2R4 TAS2R40 TAS2R41 TAS2R7	Sus scrofa (pig)	G58161NS
GDP-fucose biosynthesis	Fucose kinase GDP-L-fucose synthase GDP-mannose 4,6-dehydratase L-fucose mutarotase Solute carrier family 35 member C1	A0A287A769 A0A5G2QJW6 A0A5G2QRL7 A0A5G2R675 F1SAC0	FCSK FUOM GFUS GMDS SLC35C1	Sus scrofa (pig)	G85196CF G96881BQ
Glycoprotein hormones	Follitropin subunit beta Glycoprotein hormones alpha chain Inhibin alpha chain Inhibin beta A chain Inhibin beta B chain Inhibin beta C chain preproprotein Inhibin subunit beta E Lutropin subunit beta Thyrotropin subunit beta	A0A286ZIJ6 A0A287BPF5 F1SKG1 P01219 P01224 P01228 P01232 P03970 P04087	CGA FSHB INHA INHBA INHBB INHBC INHBE LHB TSHB	Sus scrofa (pig)
Antagonism of Activin by Follistatin	Follistatin Follistatin Inhibin beta A chain Inhibin beta B chain	A0A287BPF5 F1SLQ4 P03970 P10669	FST INHBA INHBB	Sus scrofa (pig)
Hormone ligand-binding receptors	Follicle-stimulating hormone receptor Follitropin subunit beta Glycoprotein hormones alpha chain Gonadotropin releasing hormone receptor 2 Gonadotropin-releasing hormone receptor Lutropin subunit beta Lutropin-choriogonadotropic hormone receptor Progonadoliberin-1 Progonadoliberin Thyrotropin receptor Thyrotropin subunit beta	A0A287AY01 A0A287BBU3 F1SDF3 I3L9Z2 P01219 P01224 P01228 P01232 P16582 P49921 P49922	CGA FSHB FSHR GNRH GNRH1 GNRH2 GNRHR GNRHR2 LHB LHCGR TSHB TSHR	Sus scrofa (pig)
RIPK1-mediated regulated necrosis	Flotillin-1 Flotillin Mixed lineage kinase domain like pseudokinase Programmed cell death 6 interacting protein Receptor interacting serine/threonine kinase 1 Syndecan binding protein non-specific serine/threonine protein kinase	A0A287AG10 A0A287AH24 A0A287ALN0 A0A287BRT1 A0A5G2R6P0 F1SGQ6 Q767L6	FLOT1 FLOT2 MLKL PDCD6IP RIPK1 RIPK3 SDCBP	Sus scrofa (pig)
Ficolins bind to repetitive carbohydrate structures on the target cell surface	Ficolin (collagen/fibrinogen domain containing lectin) 2 (hucolin) Ficolin (collagen/fibrinogen domain containing) 1 MBL associated serine protease 1 MBL associated serine protease 2	A0A5G2QE59 A0A5G2QP75 A0A8W4FNY0 K7GKU8	FCN1 FCN2 MASP1 MASP2	Sus scrofa (pig)	G49108TO G57321FI
Extracellular matrix organization	Fibronectin	F1SS24	FN1	Sus scrofa (pig)
Cellular hexose transport	Fibroblast growth factor Major facilitator superfamily domain containing 4B Sodium/glucose cotransporter 1 Sodium/mannose cotransporter SLC5A10 Solute carrier family 2 member 11 Solute carrier family 2 member 6 Solute carrier family 2 member 7 Solute carrier family 2 member 8 Solute carrier family 2 member 9 Solute carrier family 2, facilitated glucose transporter member 10 Solute carrier family 2, facilitated glucose transporter member 12 Solute carrier family 2, facilitated glucose transporter member 1 Solute carrier family 2, facilitated glucose transporter member 2 Solute carrier family 2, facilitated glucose transporter member 2 Solute carrier family 2, facilitated glucose transporter member 3 Solute carrier family 2, facilitated glucose transporter member 4 Solute carrier family 45 member 3 Solute carrier family 5 member 2 Solute carrier family 5 member 4 Solute carrier family 5 member 9 Sugar transporter SWEET	A0A286ZVH1 A0A287AF62 A0A287AYR1 A0A287BJ50 A0A480HHY7 A0A5G2Q9A3 A0A5G2QCF1 A0A5G2R5M2 A0A8W4FPK7 C6JWG4 F1RF44 F1RGR5 F1RIH9 F1RLV1 F1RZP2 F1SB19 I3LQQ9 O62786 O62787 P20303 P31636	FGF21 GLUT1 GLUT2 GLUT3 MFSD4B SAAT1 SGLT3 SLC2A1 SLC2A10 SLC2A11 SLC2A12 SLC2A2 SLC2A3 SLC2A4 SLC2A6 SLC2A7 SLC2A8 SLC2A9 SLC45A3 SLC50A1 SLC5A1 SLC5A10 SLC5A2 SLC5A4 SLC5A9	Sus scrofa (pig)	G58161NS G70323CJ

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