GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	March 20, 2024
ECODAB	April 1, 2019

Displaying entries **101 - 125** of **360** in total

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Pathway Name	Protein Name	UniProt ID	Gene Symbol	Organism ▼	GlyTouCan ID
Regulation of Complement cascade	C5a anaphylatoxin chemotactic receptor 1 CD55 molecule (Cromer blood group) CD59 glycoprotein CD81 molecule Carboxypeptidase B2 Carboxypeptidase N catalytic chain Carboxypeptidase N subunit 2 Clusterin Clusterin Complement C1q B chain Complement C1q C chain Complement C1q subcomponent subunit A Complement C1s Complement C2 Complement C3 Complement C4A (Rodgers blood group) Complement C5 Complement C5a receptor 2 Complement C7 Complement C8 alpha chain Complement C8 gamma chain Complement component C6 Complement component C8 beta chain Complement component C9 Complement factor B Complement factor H Complement factor I Ig lambda chain C region Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Immunoglobulin V-set domain-containing protein Immunoglobulin V-set domain-containing protein Plasma protease C1 inhibitor Prothrombin Sushi domain-containing protein Sushi domain-containing protein Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein Vitronectin complement subcomponent C1r	A0A075B7I6 A0A0A0MY58 A0A286ZIM1 A0A286ZJL9 A0A286ZKR7 A0A286ZLN6 A0A286ZMU4 A0A286ZP42 A0A286ZQH2 A0A286ZSJ7 A0A286ZSX6 A0A286ZTI5 A0A286ZU07 A0A286ZUL8 A0A287A3T6 A0A287A7S8 A0A287AA42 A0A287ADE7 A0A287AE51 A0A287AFQ4 A0A287AIM8 A0A287AKW2 A0A287ALJ6 A0A287AM45 A0A287AM58 A0A287ANU5 A0A287AP28 A0A287APG4 A0A287AQ20 A0A287AT36 A0A287AU93 A0A287AUR4 A0A287AWH3 A0A287AWQ8 A0A287AYC4 A0A287B1Y4 A0A287B5G0 A0A287B6Q2 A0A287BAB3 A0A287BD18 A0A287BDV3 A0A287BH28 A0A287BHK5 A0A287BLF6 A0A287BLH9 A0A287BMT4 A0A287BNF7 A0A287BNX9 A0A287BRE1 A0A480RJC3 A0A5G2NLY0 A0A5G2Q7F8 A0A5G2Q7Q6 A0A5G2QCL1 A0A5G2QHE8 A0A5G2QNN2 A0A5G2QXT5 A0A5G2R8T9 A0A5G2R9V1 A0A5S8KLN1 A0A8W4F6L3 A0A8W4F7N5 A0A8W4F807 A0A8W4F8A6 A0A8W4F8U6 A0A8W4F9I3 A0A8W4FA34 A0A8W4FAN5 A0A8W4FC14 A0A8W4FC15 A0A8W4FC67 A0A8W4FDG3 A0A8W4FDT9 A0A8W4FEK6 A0A8W4FEL9 A0A8W4FGI9 A0A8W4FGK7 A0A8W4FHQ3 A0A8W4FHY5 A0A8W4FI53 A0A8W4FJA1 A0A8W4FJL3 A0A8W4FL59 A0A8W4FLJ3 A0A8W4FMG3 A0A8W4FMI6 A0A8W4FN37 A0A8W4FNE8 A0A8W4FQ38 A0A8W4FQC5 A0A8W4FRI5 F1RK01 F1RL06 F1RQW7 F1S788 F1S8V7 F1S9H7 F1SIB1 F1SJW8 F1SMJ1 F1STC2 F1STC3 F1STC5 I3L6U3 I3LBK0 I3LF89 I3LUE7 K7GLM8 K7GPT9 O62680 P01846 P48819 Q29549	C1QA C1QB C1QC C1R C1S C2 C3 C4A C5 C5AR1 C5AR2 C6 C7 C8A C8B C8G C9 CD55 CD59 CD81 CFB CFH CFI CLU CPB2 CPN1 CPN2 F2 IGKV5-2 LOC100125542 LOC100523213 SERPING1 VTN	Sus scrofa (pig)
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling	Amphiregulin Betacellulin CD80 molecule CD86 molecule Epiregulin Estrogen receptor beta Estrogen receptor Fibroblast growth factor 23 Fibroblast growth factor 9 Fibroblast growth factor receptor Fibroblast growth factor receptor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fms related receptor tyrosine kinase 3 ligand GRB2 associated binding protein 1 GRB2 associated binding protein 2 Growth factor receptor bound protein 2 Hepatocyte growth factor receptor Hepatocyte growth factor Immediate early response 3 Insulin receptor substrate 1 Insulin receptor substrate 2 Insulin Interleukin 1 receptor like 1 Interleukin-1 receptor-associated kinase 4 Kit ligand Klotho beta Klotho Mast/stem cell growth factor receptor Mitogen-activated protein kinase Mitogen-activated protein kinase Multifunctional fusion protein Myeloid differentiation primary response protein MyD88 Neuregulin 2 Neuregulin 3 Phosphatidylinositol 3-kinase regulatory subunit alpha isoform 2 Phosphatidylinositol 3-kinase regulatory subunit beta Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha isoform X5 Phosphatidylinositol 4-phosphate 5-kinase type-1 beta isoform X1 Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma isoform X5 Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha Phosphatidylinositol 5-phosphate 4-kinase type-2 beta Phosphoinositide-3-kinase adaptor protein 1 Platelet-derived growth factor receptor alpha Platelet-derived growth factor receptor beta Platelet-derived growth factor subunit A Platelet-derived growth factor subunit B Pro-epidermal growth factor Pro-neuregulin-1, membrane-bound isoform Proheparin-binding EGF-like growth factor Protein phosphatase 2 regulatory subunit B'gamma Protein phosphatase 2 scaffold subunit Abeta Proto-oncogene vav Rac family small GTPase 2 Ras homolog family member G Ras-related C3 botulinum toxin substrate 1 Receptor protein-tyrosine kinase Receptor protein-tyrosine kinase Receptor protein-tyrosine kinase Receptor protein-tyrosine kinase Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform Serine/threonine-protein phosphatase Striatin T-cell-specific surface glycoprotein CD28 TNF receptor-associated factor 6 Transforming growth factor alpha Tyrosine-protein kinase Fyn Tyrosine-protein kinase receptor Tyrosine-protein kinase Tyrosine-protein kinase Tyrosine-protein phosphatase non-receptor type non-specific serine/threonine protein kinase phosphatidylinositol-4,5-bisphosphate 3-kinase phosphatidylinositol-4,5-bisphosphate 3-kinase phosphatidylinositol-4,5-bisphosphate 3-kinase receptor protein-tyrosine kinase	A0A140TAK4 A0A286ZJM1 A0A286ZQX2 A0A286ZSM8 A0A287A231 A0A287A4F0 A0A287A6I2 A0A287A9P4 A0A287AAE4 A0A287ADF0 A0A287AFX3 A0A287APB4 A0A287AU44 A0A287AXR0 A0A287AYB4 A0A287AZM9 A0A287B3V5 A0A287B510 A0A287B5E0 A0A287B630 A0A287B726 A0A287B929 A0A287BCW9 A0A287BG34 A0A287BGB1 A0A287BGK8 A0A287BK67 A0A480ECT1 A0A480I421 A0A480J4F4 A0A480LMF4 A0A480NH74 A0A5G2QBP1 A0A5G2QNL8 A0A5G2QUY7 A0A5G2R1H6 A0A5G2R1K1 A0A5G2R7G2 A0A5G2RG05 A0A5K1UB41 A0A5K1UPW2 A0A8W4FI56 A0A8W4FMH5 A0A8X9AEI7 A1Y2K1 A7XUJ6 B6E241 F1RL75 F1RM38 F1RQR5 F1RSR6 F1RVI6 F1RWM5 F1RX68 F1RY78 F1RY80 F1RZU1 F1S2V7 F1S3B8 F1S4P0 F1S916 F1SB93 F1SCL0 F1SET9 F1SKR9 F1SLD3 F1SMG2 F1SRR6 F1SSQ9 F1SV94 F6Q7E6 I3L560 I3LG49 I3LKR6 I3LLF1 I3LR27 K7GMQ2 K7GMT0 K7GMU1 K7GPR7 K7GQJ1 P01315 P54612 P67776 Q01580 Q29040 Q2QLE0 Q95L12 Q9BDH4 Q9BE99	AREG BTC CD28 CD80 CD80/B7-1 CD86 DTR EGF EGFR ERBB2 ERBB3 ERBB4 EREG ESR ESR1 ESR2 FGF1 FGF10 FGF16 FGF18 FGF19 FGF2 FGF20 FGF22 FGF23 FGF3 FGF4 FGF5 FGF6 FGF8 FGF9 FGFR1 FGFR4 FLT3 FLT3LG FYN Fgf4 GAB1 GAB2 GRB2 HBEGF HEGFL HGF IER3 IL1RL1 INS INSR IRAK1 IRAK4 IRS1 IRS2 KIT KITLG KL KLB LCK MAPK1 MAPK3 MET MYD88 NR3A1 NRG1 NRG2 NRG3 PDGFA PDGFB PDGFRA PDGFRB PIK3AP1 PIK3CA PIK3CB PIK3CD PIK3R1 PIK3R2 PIP4K2A PIP4K2B PIP5K1A PIP5K1B PIP5K1C PPP2CA PPP2CB PPP2R1A PPP2R1B PPP2R5A PPP2R5B PPP2R5C PPP2R5D PTPN11 RAC1 RAC2 RHOG SRC STRN TGFA TRAF6 VAV1	Sus scrofa (pig)
Formation of ATP by chemiosmotic coupling	ATP synthase F1 subunit epsilon ATP synthase lipid-binding protein ATP synthase lipid-binding protein ATP synthase lipid-binding protein ATP synthase protein 8 ATP synthase subunit O, mitochondrial ATP synthase subunit a ATP synthase subunit alpha, mitochondrial ATP synthase subunit beta ATP synthase subunit e, mitochondrial ATP synthase subunit f, mitochondrial ATP synthase subunit gamma ATP synthase subunit s, mitochondrial isoform X1 ATP synthase subunit	A0A286ZIA7 A0A286ZRY7 A0A287BN31 A0A8W4F7C1 A0A8W4FI02 A0A8X9AEI6 K7GLT8 K7GS22 P80021 Q2EN81 Q35914 Q35915 Q95339 Q9MYT8	ATP5A1 ATP5A2 ATP5F1A ATP5F1B ATP5F1C ATP5F1E ATP5I ATP5J2 ATP5MC2 ATP5MC3 ATP5ME ATP5MF ATP5O ATP5PO ATP6 ATP8 ATPASE6 ATPASE8 DMAC2L LOC100519871 MT-ATP6 MT-ATP8 MTATP6 MTATP8	Sus scrofa (pig)
Signaling by Insulin receptor	Insulin Tyrosine-protein kinase receptor	F1SCL0 P01315	INS INSR	Sus scrofa (pig)
Erythropoietin activates Phosphoinositide-3-kinase (PI3K)	Erythropoietin receptor Erythropoietin GRB2 associated binding protein 1 Insulin receptor substrate 2 Phosphatidylinositol 3-kinase regulatory subunit alpha isoform 2 Phosphoinositide 3-kinase regulatory subunit 5 Tyrosine-protein kinase JAK2 Tyrosine-protein kinase phosphatidylinositol-4,5-bisphosphate 3-kinase phosphatidylinositol-4,5-bisphosphate 3-kinase phosphatidylinositol-4,5-bisphosphate 3-kinase phosphatidylinositol-4,5-bisphosphate 3-kinase	A0A286ZR76 A0A287B726 A0A5K1UB41 A0A5K1UPW2 A0A8X9AEI7 F1RT53 F1SKR9 I3LJB7 K7GMT0 O19064 P49157 Q9MYZ9	EPO EPOR GAB1 IRS2 JAK2 LYN PIK3CA PIK3CB PIK3CD PIK3CG PIK3R1 PIK3R5	Sus scrofa (pig)
Vitamin C (ascorbate) metabolism	Cytochrome b5 Glutathione S-transferase omega-1 NADH-cytochrome b5 reductase Solute carrier family 2, facilitated glucose transporter member 1 Solute carrier family 2, facilitated glucose transporter member 3 Solute carrier family 23 member 1	A0A5G2QPB6 I3LCS3 O62787 P00172 P20303 Q9N1F5	CYB5 CYB5A CYB5R3 GLUT1 GLUT3 GSTO1 SLC23A1 SLC2A1 SLC2A3	Sus scrofa (pig)
Translocation of ZAP-70 to Immunological synapse	Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein MHC class II DR-alpha MHC class II antigen MHC class II histocompatibility antigen SLA-DRB1 SLA class II histocompatibility antigen, DQ haplotype D alpha chain SLA-DQ beta1 domain T-cell surface glycoprotein CD3 delta chain T-cell surface glycoprotein CD3 epsilon chain T-cell surface glycoprotein CD3 gamma chain T-cell surface glycoprotein CD3 zeta chain T-cell surface glycoprotein CD4 Tyrosine-protein kinase Uncharacterized protein protein-tyrosine-phosphatase	A0A286ZKB7 A0A286ZUJ9 A0A287AC24 A0A287AT33 A0A287B968 A0A287BD80 A0A287BF11 A0A287BQ31 A0A5G2QCN4 A0A8W4F9V5 A0A8W4FBN9 A0A8W4FJW4 A0A8W4FNK4 A0A8W4FP49 A0A8X9AEU9 F1S6S1 F1S975 F1SV94 I3L556 I3LAQ5 K7GS60 P15981 Q5PXD3 Q764N2 Q7YQ94 Q85ZW4	CD247 CD3D CD3E CD3G CD4 DRA HLA-DRA LCK LOC100153139 PTPN22 SLA-DQA SLA-DQA1 SLA-DQB1 SLA-DR SLA-DRA SLA-DRA1 SLA-DRB1	Sus scrofa (pig)
Glycerophospholipid biosynthesis	Acylglycerol kinase, mitochondrial Copine 1 Copine 3 Copine 6	A0A287B2X0 B8XSJ0 F1S4V8 F1SGL6	AGK CPNE1 CPNE3 CPNE6	Sus scrofa (pig)
PTK6 promotes HIF1A stabilization	Glycoprotein nmb Hypoxia-inducible factor 1-alpha Proheparin-binding EGF-like growth factor Receptor protein-tyrosine kinase Tyrosine-protein kinase non-specific serine/threonine protein kinase	A0A286ZJF6 A0A286ZYS4 A0A287B2Q0 A0A5G2QBP1 F1SHN7 Q01580	DTR EGFR GPNMB HBEGF HEGFL HIF1A LRRK2 PTK6	Sus scrofa (pig)
Regulation of TNFR1 signaling	Baculoviral IAP repeat containing 2 CAP-Gly domain-containing linker protein 3 Caspase 9 Caspase-8 E2 ubiquitin-conjugating enzyme E2 ubiquitin-conjugating enzyme E3 ubiquitin-protein ligase CHIP FAS-associated death domain protein IkappaB kinase Inhibitor of nuclear factor kappa B kinase subunit epsilon Inhibitor of nuclear factor kappa-B kinase subunit alpha MAP kinase-activating death domain protein MAPK activated protein kinase 2 NF-kappa-B essential modulator Optineurin Polyubiquitin-C Putative inhibitor of apoptosis RBR-type E3 ubiquitin transferase RING-type E3 ubiquitin transferase RanBP-type and C3HC4-type zinc finger-containing protein 1 Receptor interacting serine/threonine kinase 1 Serine/threonine-protein kinase Signal peptide peptidase like 2A Signal peptide peptidase like 2B Small ribosomal subunit protein RACK1 Spermatogenesis-associated protein 2 TANK binding kinase 1 TNF receptor-associated factor TNF receptor-associated factor Tax1 binding protein 1 Tumor necrosis factor receptor superfamily member 1A Tumor necrosis factor receptor type 1-associated DEATH domain protein Tumor necrosis factor Ubiquitin B Ubiquitin C Ubiquitin carboxyl-terminal hydrolase 4 Ubiquitin carboxyl-terminal hydrolase CYLD Ubiquitin carboxyl-terminal hydrolase Ubiquitin carboxyl-terminal hydrolase Ubiquitin conjugating enzyme E2 D3 Ubiquitin-conjugating enzyme E2 D2 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein ubiquitinyl hydrolase 1 ubiquitinyl hydrolase 1 ubiquitinyl hydrolase 1	A0A286ZI91 A0A286ZVH7 A0A286ZYB8 A0A287A5Q1 A0A287AL42 A0A287AQJ4 A0A287AUG2 A0A287AZA7 A0A287B5E3 A0A287B9E9 A0A287BGB4 A0A287BGG6 A0A287BPE4 A0A287BRT1 A0A288CFV1 A0A2C9F3G2 A0A5G2QUT6 A0A5G2R1D9 A0A8W4FES8 A7U5U2 A9QT41 F1RFR1 F1RLF4 F1RVZ4 F1RYM5 F1S196 F1S6A4 F1S7J3 F1S8G9 F1S8V5 F1S911 F1SDG3 F1SME2 F1SUV9 I3LH37 I3LI16 K7GLC2 M9MMN5 O62640 P0CG68 P23563 P63246 Q06AA8 Q56VC2 Q56VC3 Q7YS99	BIRC2 CASP8 CASP9 CHUK CLIP3 CYLD FADD GNB2L1 IKBKB IKBKE IKBKG MADD MAPKAPK2 MIB2 OPTN OTUD1 OTUD7B PIAP RACK1 RBCK1 RIPK1 RNF31 RPS27A SPATA2 SPPL2A SPPL2B STUB1 TAX1BP1 TBK1 TNF TNFA TNFAIP3 TNFRSF1A TNFRSF6 TNFSF2 TRADD TRAF1 TRAF2 UBA52 UBB UBC UBE2D1 UBE2D2 UBE2D3 UBE2L3 ULK1 USP2 USP21 USP4	Sus scrofa (pig)
Keratan sulfate degradation	Aggrecan core protein Beta-galactosidase Beta-galactosidase Beta-galactosidase Beta-hexosaminidase Beta-hexosaminidase Fibromodulin Galactosidase beta 1 like Keratocan Lumican Mimecan N-acetylglucosamine-6-sulfatase Osteomodulin Prolargin	A0A0H5ANC0 A0A287A524 A0A287A7V3 A0A287B239 A0A287B863 A0A5G2R907 D0G6X8 F1S6B4 F1S6B5 F1SQ08 F1SQ09 F1SR82 F1SUE2 I3LGI9	ACAN FMOD GLB1 GLB1L GLB1L2 GLB1L3 GNS HEXA HEXB KERA LUM OGN OMD PRELP	Sus scrofa (pig)	G09546QO G20239CJ G27025MB G50451AA G80016QC G82768YB G85384LV
Ligand-dependent caspase activation	Caspase-8 FAS-associated death domain protein Lymphocyte antigen 96 Monocyte differentiation antigen CD14 Receptor interacting serine/threonine kinase 1 TIR domain-containing adapter molecule 1 TIR domain-containing adapter molecule 2 Toll-like receptor 4	A0A287BMU9 A0A287BRT1 A0A480K9W0 A2SW51 A7BG67 K9J6H0 Q56VC2 Q56VC3	CASP8 CD14 FADD LY96 RIPK1 TICAM1 TICAM2 TLR4 TNFRSF6	Sus scrofa (pig)
Toll Like Receptor 4 (TLR4) Cascade	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma Bactericidal permeability-increasing protein CD180 antigen Integrin beta Integrin subunit alpha M Lipopolysaccharide-binding protein Lymphocyte antigen 86 Lymphocyte antigen 96 Monocyte differentiation antigen CD14 TIR domain-containing adapter molecule 2 Toll-like receptor 4 dynamin GTPase dynamin GTPase dynamin GTPase	A0A287A869 A0A287AK86 A0A287AN09 A0A287B5Y6 A0A287B8X7 A0A287BLV6 A0A287BMU9 A0A480K9W0 A0A5G2REH3 A2SW51 A7BG67 F1S475 I3LCZ7 Q7YRL4	BPI CD14 CD180 DNM1 DNM2 DNM3 ITGAM ITGB2 LBP LY64 LY86 LY96 PLCG2 TICAM2 TLR4	Sus scrofa (pig)
Post-translational protein phosphorylation	Adipose triglyceride lipase Albumin Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase A Alpha-2-HS-glycoprotein Alpha-L-fucosidase Alpha-fetoprotein Ameloblastin Amelogenin Amyloid beta like protein 2 Amyloid-beta A4 protein Amyloid-beta precursor protein Anoctamin Antithrombin-III Apolipoprotein A-I Apolipoprotein A-II Apolipoprotein A-V Apolipoprotein B Apolipoprotein E Apolipoprotein L3 isoform 1 Apolipoprotein L3 isoform X1 BPI fold containing family B member 2 Bone morphogenetic protein 15 Bone morphogenetic protein 4 CCN family member 1 Cadherin-2 Chordin like 1 Coagulation factor V Complement C3 Complement C4A (Rodgers blood group) Cystatin C Cytoskeleton associated protein 4 Dentin matrix acidic phosphoprotein 1 Disintegrin and metalloproteinase domain-containing protein 10 DnaJ homolog subfamily C member 3 Endoplasmin Extracellular serine/threonine protein kinase FAM20C isoform X1 FAM20A golgi associated secretory pathway pseudokinase Fibrinogen alpha chain Fibrinogen gamma chain Fibroblast growth factor 23 Fibronectin Follistatin-related protein 1 Galectin Glucosidase 2 subunit beta Glypican-3 Golgi membrane protein 1 Growth arrest specific 6 Heparin cofactor 2 Histidine rich calcium binding protein Insulin like growth factor binding protein 7 Insulin-like growth factor-binding protein 1 Insulin-like growth factor-binding protein 3 Insulin-like growth factor-binding protein 4 Insulin-like growth factor-binding protein 5 Inter-alpha-trypsin inhibitor heavy chain H2 Interleukin-6 Kinectin 1 Kininogen 1 Latent transforming growth factor beta binding protein 1 MIA SH3 domain ER export factor 3 Macrophage colony-stimulating factor 1 Matrilin 3 Matrix extracellular phosphoglycoprotein Matrix remodeling-associated protein 8 Melanotransferrin Membrane bound transcription factor peptidase, site 1 Menin Metalloproteinase inhibitor 1 Multiple EGF like domains 6 Nucleobindin-1 Osteopontin Proprotein convertase subtilisin/kexin type 9 Protein disulfide-isomerase A6 Protein disulfide-isomerase Reticulocalbin-1 SPARC like 1 Secreted phosphoprotein 24 Secretogranin-1 Secretogranin-2 Secretogranin-3 Serine protease 23 Serotransferrin Serpin family A member 1 Stanniocalcin-2 Sulfhydryl oxidase Syndecan Tenascin C Tenascin N Trans-Golgi network integral membrane protein 2 Transmembrane protein 132A Uteroferrin associated basic protein-2 VGF nerve growth factor inducible Versican core protein Vitamin K-dependent protein C Wolframin ER transmembrane glycoprotein [Wnt protein] O-palmitoleoyl-L-serine hydrolase von Willebrand factor A domain-containing protein 1	A0A286ZQC7 A0A286ZRX5 A0A286ZTE6 A0A286ZU78 A0A286ZWQ1 A0A286ZZH4 A0A287A5V7 A0A287AF70 A0A287AFA5 A0A287AG13 A0A287AKS6 A0A287ALA1 A0A287AXR0 A0A287AYJ5 A0A287B049 A0A287B0E4 A0A287BAY9 A0A287BDE8 A0A287BFZ3 A0A287BHU3 A0A287BP22 A0A287BPE2 A0A288CFV5 A0A480P2S5 A0A480Y2E3 A0A481BCM9 A0A481BLI9 A0A5G2Q797 A0A5G2QCF0 A0A5G2QCL1 A0A5G2QN69 A0A5G2QS80 A0A5G2QUR1 A0A5G2QUU1 A0A5G2QXX3 A0A5G2R599 A0A5G2R6R2 A0A5G2RA54 A0A5G2RDD7 A0A5G2RIA8 A0A5G2RIT7 A0A8W4FB62 A0A8W4FDT9 A0A8W4FKM9 A5JT15 A7LJT9 E0A8P1 E2I6L6 E9KYT3 F1REZ2 F1RIA4 F1RIN7 F1RJE3 F1RM45 F1RPW2 F1RQR2 F1RV24 F1RV73 F1RVH7 F1RWV2 F1RX36 F1S0L5 F1S4I1 F1S596 F1S708 F1SAM3 F1SCE4 F1SCU3 F1SGP8 F1SJZ1 F1SM14 F1SPP8 F1SPU1 F1SQX4 F1SS24 F1SSN5 F1STR4 F6PZL5 I3LBK9 I3LGB2 I3LIW9 I3LLG6 I3LU40 I3LUI4 I3LUV5 I3LVB2 K7GQ93 K7GRE3 O02668 O77633 P14287 P45561 P79307 Q0Z8R0 Q28989 Q8MJ76 Q9GLG4	A4 AD1 ADAM10 AFP AHSG ALB AMBN AMEL ANO8 APLP2 APOA1 APOA2 APOA5 APOB APOE APP ATGL BMP15 BMP4 BPIFB2 C3 C4A CCN1 CDH2 CHGB CHRDL1 CKAP4 CSF1 CST3 DMP1 DNAJC3 F5 FAM20A FAM20C FGA FGF23 FGG FN1 FSTL1 FUCA2 GAS6 GOLM1 GPC3 HRC HSP90B1 IGFBP1 IGFBP3 IGFBP4 IGFBP5 IGFBP7 IL-6 IL6 ITIH2 KNG1 KTN1 LGALS1 LOC100156062 LOC100738836 LOC106510284 LTBP1 MATN3 MBTPS1 MEGF6 MELTF MEN1 MEPE MGAT4A MIA3 MXRA8 NOTUM NUCB1 OPN P4HB PCSK9 PDIA6 PNPLA2 PRKCSH PROC PRSS23 QSOX1 RCN1 SCG2 SCG3 SDC2 SERPINA1 SERPINC1 SERPIND1 SPARCL1 SPP1 SPP2 STC2 TF TIMP1 TMEM132A TNC TNN UABP-2 VCAN VGF VWA1 WFS1 bmp4	Sus scrofa (pig)
TNF receptor superfamily (TNFSF) members mediating non-canonical NF-kB pathway	B-cell activating factor Baculoviral IAP repeat containing 2 CD40 ligand Lymphotoxin beta receptor Lymphotoxin-alpha Lymphotoxin-beta Mitogen-activated protein kinase kinase kinase 14 Putative inhibitor of apoptosis TNF receptor superfamily member 11a TNF receptor superfamily member 12A TNF receptor superfamily member 13C TNF receptor-associated factor TNF receptor-associated factor TNF superfamily member 11 TNF superfamily member 12 Tumor necrosis factor receptor superfamily member 5	A0A287AJ47 A0A287AWB6 A0A5G2Q934 A0A8W4FAU5 A0A8W4FCV1 A0MTC9 F1RJX1 F1RR25 F1RVZ4 I3L7R8 I3L871 I3LH37 K7GN73 O62640 P26445 Q8SQ34	BIRC2 CD40 CD40LG LTA LTB LTBR MAP3K14 PIAP TNFB TNFRSF11A TNFRSF12A TNFRSF13C TNFRSF5 TNFSF1 TNFSF11 TNFSF12 TNFSF13B TRAF2 TRAF3	Sus scrofa (pig)
HSF1-dependent transactivation	AKT1 substrate 1 Alpha-crystallin B chain Calcium/calmodulin-dependent protein kinase type II subunit delta Heat shock 70 kDa protein 1-like Heat shock 70 kDa protein 1B Heat shock cognate 71 kDa protein Heat shock factor protein 1 Heat shock factor-binding protein 1 Heat shock protein HSP 90-alpha Heat shock protein HSP 90-alpha Heat shock protein HSP 90-beta Heat shock protein beta-8 Regulatory associated protein of MTOR complex 1 Serine/threonine-protein kinase mTOR Target of rapamycin complex subunit LST8 Uncharacterized protein calcium/calmodulin-dependent protein kinase calcium/calmodulin-dependent protein kinase calcium/calmodulin-dependent protein kinase	A0A286ZKC5 A0A286ZWK2 A0A287BCC5 A0A287BMT8 A0A287BQU9 A0A5G2QCQ9 A0A8I8C3K7 A0A8W4FJ36 A5A8V7 F1RFA8 F1RHR8 F1RHU2 F1RL74 F1RSM7 I3L942 O02705 Q6S4N2 Q7M2W6 Q95266	AKT1S1 CAMK2A CAMK2B CAMK2D CAMK2G CRYAB HSBP1 HSF1 HSP90A HSP90AA1 HSP90AB1 HSPA1B HSPA1L HSPA8 HSPB8 HSPCA MLST8 MTOR RPTOR	Sus scrofa (pig)
Regulation of CDH11 function	ADAM metallopeptidase domain 19 ADAM metallopeptidase domain 33 Angiomotin Angiopoietin-related protein 4 Cadherin 11 Catenin beta-1 Catenin delta 1 Junction plakoglobin Junction plakoglobin	A0A287AHV9 A0A287ASR6 A0A2C9F3E9 A0A5G2QJC4 F1RFU7 F1RWT7 F6QAP1 Q2TNK5 Q8WNW3	ADAM19 ADAM33 AMOT ANGPTL4 CDH11 CTNNB1 CTNND1 JUP Jup PGAR	Sus scrofa (pig)
Platelet homeostasis	P2X purinoceptor P2X purinoceptor P2X purinoceptor P2X purinoceptor P2X purinoceptor P2X purinoceptor P2X purinoceptor Platelet-activating factor acetylhydrolase	A0A286ZJX8 A0A286ZYA9 A0A287AVK8 A0A5G2QGJ3 A0A8W4FN26 F1RI70 F1RNN5 I3L7H5	P2RX1 P2RX2 P2RX3 P2RX4 P2RX5 P2RX6 P2RX7 PAFAH2	Sus scrofa (pig)
Platelet degranulation	Actin, cytoplasmic 2 Actinin alpha 2 Albumin Alpha-1-B glycoprotein Alpha-2-HS-glycoprotein Alpha-2-antiplasmin isoform X2 Alpha-2-macroglobulin Alpha-actinin-1 Alpha-actinin-4 Amyloid beta like protein 2 Amyloid-beta A4 protein Amyloid-beta precursor protein Annexin Apolipoprotein A-I Beta-2-glycoprotein 1 Bromodomain and PHD finger containing 3 C-type lectin domain family 3 member B CD109 antigen isoform 1 preproprotein CYFIP related Rac1 interactor B Calmodulin 3 Cathepsin W Chitinase domain-containing protein 1 Clusterin Clusterin Coagulation factor V Coagulation factor XIII A chain Complement factor D Cystic fibrosis transmembrane conductance regulator Endonuclease domain containing 1 Extracellular matrix protein 1 FERM domain containing kindlin 3 Fibrinogen alpha chain Fibrinogen beta chain Fibrinogen gamma chain Fibronectin Filamin A Fructose-bisphosphate aldolase GTP binding protein 2 Galectin-3-binding protein Growth arrest specific 6 Hepatocyte growth factor Histidine-rich glycoprotein Hyaluronan binding protein 4 Immunoglobulin superfamily containing leucine rich repeat Insulin-like growth factor I Insulin-like growth factor II Insulin-like growth factor II Integrin beta Integrin subunit alpha 2b Inter-alpha-trypsin inhibitor heavy chain 4 Inter-alpha-trypsin inhibitor heavy chain H3 Kininogen 1 LHFPL tetraspan subfamily member 2 Left-right determination factor Left-right determination factor Lipocalin/cytosolic fatty-acid binding domain-containing protein Lymphocyte antigen 6 complex locus G6F Lysosomal associated membrane protein 2 MICOS complex subunit Metalloproteinase inhibitor 1 Metalloproteinase inhibitor 3 Multimerin 1 NHL repeat containing 2 Obg-like ATPase 1 Palladin isoform X4 Phosphatase and actin regulator Plasma protease C1 inhibitor Plasminogen activator inhibitor 1 Plasminogen activator inhibitor 1 Plasminogen Platelet and endothelial cell adhesion molecule 1 Platelet basic protein Platelet endothelial cell adhesion molecule Platelet glycoprotein 4 Platelet-derived growth factor subunit A Platelet-derived growth factor subunit B Pleckstrin Prenylcysteine oxidase 1 like Pro-epidermal growth factor Prosaposin Protein FAM3C Protocadherin 7 Retinoic acid receptor responder protein 2 SPARC SPARC Saccharopine dehydrogenase-like oxidoreductase Secreted phosphoprotein 24 Secretogranin-3 Serglycin Serotransferrin Serpin domain-containing protein Serpin family A member 1 Serpin family A member 4 Sulfhydryl oxidase Superoxide dismutase [Cu-Zn] Synaptotagmin like 4 Syntaxin-binding protein 2 Talin 1 Tetraspanin Tetraspanin Thrombospondin 1 Thymosin beta-4 Torsin family 4 member A Transforming growth factor beta-1 proprotein Transforming growth factor beta-3 proprotein Transforming growth factor beta-3 proprotein Transforming growth factor beta Transgelin Tubulin alpha-4A chain Uteroferrin associated basic protein-2 Vascular endothelial growth factor B Vascular endothelial growth factor C Vascular endothelial growth factor D Vascular permeability factor Vinculin Vitamin K-dependent protein S WD repeat domain 1 cytochrome-b5 reductase p-selectin small monomeric GTPase von Willebrand factor	A0A1L6ZA08 A0A286ZFW3 A0A286ZQC7 A0A286ZS02 A0A286ZTE6 A0A286ZTH5 A0A286ZUY9 A0A286ZV08 A0A286ZXF1 A0A286ZZX3 A0A287A231 A0A287A5V7 A0A287A6Q0 A0A287AA77 A0A287ADF0 A0A287AKS6 A0A287ALA1 A0A287AR46 A0A287AW81 A0A287AYJ5 A0A287B0D0 A0A287B850 A0A287B9B3 A0A287BAK1 A0A287BAY9 A0A287BBR6 A0A287BDE8 A0A287BFL9 A0A287BFY0 A0A287BH21 A0A287BJL7 A0A287BPI5 A0A288CFV5 A0A480TAV6 A0A480XYV1 A0A480Y2E3 A0A481B9A6 A0A481CKM4 A0A5G2Q8I9 A0A5G2QA44 A0A5G2QE94 A0A5G2QLU2 A0A5G2QPB0 A0A5G2QT56 A0A5G2QUU1 A0A5G2QWK6 A0A5G2QXC2 A0A5G2QXR3 A0A5G2QXX3 A0A5G2QZI2 A0A5G2QZT2 A0A5G2R0I4 A0A5G2R655 A0A5G2R6P1 A0A5G2R7K7 A0A5G2R7M3 A0A5G2RDM3 A0A5G2RH83 A0A5G2RIC7 A0A5G2RLP2 A0A5S8KLN1 A0A8W4FBV2 A0A8W4FIF1 A0A8W4FMH5 F1RI39 F1RJ93 F1RPW2 F1RQ01 F1RQ05 F1RQY8 F1RT19 F1RU23 F1RVY0 F1RW71 F1RWV2 F1RX36 F1RX37 F1S1M2 F1S2F5 F1S5H7 F1S8P1 F1S8R0 F1SB93 F1SCE4 F1SH96 F1SIT0 F1SJW8 F1SL22 F1SM14 F1SPK8 F1SQU4 F1SRC8 F1SS24 F1SS26 F1STI9 F2Z5C1 I3L695 I3LC64 I3LKI1 I3LLY3 I3LQQ6 I3LS26 K7GKY0 K7GS31 K7GSJ9 K9IVR7 P04178 P07200 P15203 P16545 P20112 P23695 P26234 P43030 P51779 P79307 P79335 Q29549 Q3HUX1 Q95242 Q95274	A1BG A2M A4 ABCC4 ACTG1 ACTN1 ACTN2 ACTN4 AD1 AHSG ALB ALDOA ANXA5 APLP2 APOA1 APOH APOOL APP BRPF3 CALM3 CD109 CD36 CD63 CD9 CFD CHID1 CLEC3B CLU CTSW CXCL7 CYB5R1 CYRIB DF ECM1 EGF ENDOD1 F13A1 F5 FAM3C FERMT3 FGA FGB FGG FLNA FN1 GAS6 GTPBP2 HABP4 HGF HRG IGF1 IGF2 ISLR ITGA2B ITGB3 ITIH3 ITIH4 KNG1 LAMP2 LEFTY2 LGALS3BP LHFPL2 LOC100156325 LOC100524517 LY6G6F MMRN1 NHLRC2 OLA1 ORM1 PAI1 PALLD PCDH7 PCYOX1L PDGFA PDGFB PECAM1 PHACTR2 PLANH1 PLEK PLG PPBP PROS1 PSAP QSOX1 RAB27B RARRES2 SCCPDH SCG3 SCYB7 SELP SERPINA1 SERPINA4 SERPINE1 SERPINF2 SERPING1 SOD1 SPARC SPP2 SRGN STXBP2 SYTL4 TAGLN2 TF TGFB1 TGFB2 TGFB3 THBS1 TIMP1 TIMP3 TLN1 TMSB4 TOR4A TUBA4A UABP-2 VCL VEGFA VEGFB VEGFC VEGFD VWF WDR1 ly6g6f	Sus scrofa (pig)
Synthesis of Leukotrienes (LT) and Eoxins (EX)	Arachidonate 5-lipoxygenase Cytochrome P450 4A11 Cytochrome P450 4A24 Cytochrome P450 family 4 subfamily A member 21 Cytochrome P450 family 4 subfamily A member 24 Cytochrome P450 family 4 subfamily A member 90 Cytochrome P450 family 4 subfamily B member 1 Cytochrome P450 family 4 subfamily F member 22 Cytochrome P450 family 4 subfamily F member 52 Dipeptidase 1 Dipeptidase 3 Dipeptidase Dipeptidase Glutathione hydrolase Leukotriene A(4) hydrolase Leukotriene C4 synthase MAPK activated protein kinase 2 Multidrug resistance-associated protein 1 Phylloquinone omega-hydroxylase CYP4F2-like Polyunsaturated fatty acid lipoxygenase ALOX15 Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein	A0A287ABK7 A0A287AJX4 A0A287BMK6 A0A287BRK6 A0A5G2R092 A0A5K1UGB8 A0A8W4F6R7 A0A8W4F9A9 A0A8W4FCM8 A0A8W4FES8 A0A8W4FH73 A0A8W4FHR4 A0A900QA25 F1SAG6 F1SQR8 I3L719 I3LBY7 I3LEI1 I3LFR7 I3LIR7 K7GQZ4 P16469 P22412 Q8SPK1	ABCC1 ALOX15 ALOX5 CYP4A21 CYP4A23 CYP4A24 CYP4A90 CYP4B1 CYP4F22 CYP4F3 CYP4F52 DPEP1 DPEP2 DPEP3 GGT1 LOC110255311 LOC110259328 LOC110259329 LTA4H LTC4S MAPKAPK2 RDP	Sus scrofa (pig)
TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)	Cingulin E3 ubiquitin-protein ligase Junctional adhesion molecule A Par-3 family cell polarity regulator Par-6 family cell polarity regulator alpha Polyubiquitin-C Rho/Rac guanine nucleotide exchange factor 18 Serine/threonine-protein kinase receptor TGF-beta receptor type-1 Transforming growth factor beta-1 proprotein Transforming protein RhoA Ubiquitin B Ubiquitin C Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein protein kinase C	A0A286ZZ01 A0A287A1S5 A0A287AXZ5 A0A287AZA7 A0A287BLR9 A0A2C9F3G2 A0A5G2QMD9 A0A5G2QYR6 A0A5G2RC56 A7U5U2 F1S911 I3LTD6 I3LU84 I3LVS7 P07200 P0CG68	ARHGEF18 CGN F11R PARD3 PARD6A PRKCZ RHOA RPS27A SMURF1 TGFB1 TGFBR1 TGFBR2 UBA52 UBB UBC	Sus scrofa (pig)
Phospholipase C-mediated cascade: FGFR1	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma Fibroblast growth factor 23 Fibroblast growth factor 9 Fibroblast growth factor receptor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Klotho Multifunctional fusion protein	A0A287AAE4 A0A287AFX3 A0A287AXR0 A0A287BG34 A0A287BGK8 A0A5G2R7G2 F1RM38 F1RSR6 F1RY78 F1RY80 F1SDV6 F1SET9 F1SMG2 K7GQJ1 Q95L12	FGF1 FGF10 FGF2 FGF20 FGF22 FGF23 FGF3 FGF4 FGF5 FGF6 FGF8 FGF9 FGFR1 Fgf4 KL PLCG1	Sus scrofa (pig)
Transport of vitamins, nucleosides, and related molecules	PDZ domain-containing protein 11 Sodium-dependent multivitamin transporter Solute carrier family 33 member 1	A0A287BEL5 I3LE73 Q6QA76	PDZD11 PDZK11 SLC33A1 SLC5A6	Sus scrofa (pig)
Insertion of tail-anchored proteins into the endoplasmic reticulum membrane	Aldehyde dehydrogenase family 3 member A2 Amyloid-beta A4 protein Amyloid-beta precursor protein Cytochrome b5 E2 ubiquitin-conjugating enzyme Emerin Heme oxygenase 1 Major prion protein Protein transport protein Sec61 subunit gamma SEC61 translocon subunit beta Small glutamine rich tetratricopeptide repeat co-chaperone alpha Stress-associated endoplasmic reticulum protein Syntaxin-1A Vesicle-associated membrane protein 2 Vesicle-associated membrane protein-associated protein A	A0A0U2ETD0 A0A286ZIJ7 A0A286ZTE6 A0A287B1B1 A0A287BBJ7 A0A5G2QDR3 A0A5G2QXK3 A0A5G2R276 A0A5G2RB73 F1RGA3 F2Z5P0 P00172 P32394 P49927 P79307	A4 AD1 ALDH3A2 APP CYB5 CYB5A EMD HMOX1 PRNP PRP SEC61B SEC61G SERP1 SGTA STX1A UBE2J2 VAMP2 VAPA	Sus scrofa (pig)
Signal regulatory protein family interactions	FYN binding protein 1 Growth factor receptor bound protein 2 Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Leukocyte surface antigen CD47 Signal regulatory protein alpha Src kinase-associated phosphoprotein 2 TYRO protein tyrosine kinase-binding protein non-specific protein-tyrosine kinase	A0A480KBE3 A0A8W4FCP5 B6E241 F1RJS6 I3L932 K7GKB0 K7GL06 K7GLT9 M9MMN6 Q9GKE8 Q9TU45	CD47 DAP12 FYB1 GRB2 LOC100736623 LOC100739707 LOC102161654 PTK2B SIRPA SKAP2 TYROBP	Sus scrofa (pig)

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