GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	March 20, 2024
ECODAB	April 1, 2019

Displaying entries **126 - 150** of **360** in total

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Pathway Name	Protein Name	UniProt ID	Gene Symbol ▲	Organism	GlyTouCan ID
EGFR downregulation	Amphiregulin Betacellulin Cell division control protein 42 homolog E3 ubiquitin-protein ligase CBL Endophilin-A2 Epidermal growth factor receptor pathway substrate 15 like 1 Epidermal growth factor receptor pathway substrate 15 Epiregulin Epsin 1 Growth factor receptor bound protein 2 Hepatocyte growth factor-regulated tyrosine kinase substrate Polyubiquitin-C Pro-epidermal growth factor Proheparin-binding EGF-like growth factor Protein sprouty homolog 1 Receptor protein-tyrosine kinase Rho guanine nucleotide exchange factor 7 SH3 domain containing GRB2 like 3, endophilin A3 SH3 domain containing kinase binding protein 1 Signal transducing adaptor molecule 2 Signal transducing adaptor molecule Transforming growth factor alpha Tyrosine-protein phosphatase non-receptor type Ubiquitin B Ubiquitin C Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein protein-tyrosine-phosphatase protein-tyrosine-phosphatase	A0A286ZPM4 A0A286ZQE1 A0A286ZY48 A0A287A000 A0A287A231 A0A287A519 A0A287A6I2 A0A287AR65 A0A287AZA7 A0A287AZM9 A0A287B5N2 A0A287BKD5 A0A2C9F3G2 A0A5G2Q9Y0 A0A5G2QBP1 A0A5G2QFX7 A0A5G2RE13 A7U5U2 B6E241 F1RRA2 F1S7L8 F1S911 F1SHW8 F1SLD3 I3LPZ5 P0CG68 Q007T2 Q01580 Q9BDH4	AREG ARHGEF7 BTC CBL CDC42 DTR EGF EGFR EPN1 EPS15 EPS15L1 EREG GRB2 HBEGF HEGFL HGS PTPN12 PTPN3 PTPRK RPS27A SH3GL1 SH3GL3 SH3KBP1 SPRY1 STAM STAM2 TGFA UBA52 UBB UBC	Sus scrofa (pig)
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling	Amphiregulin Betacellulin CD80 molecule CD86 molecule Epiregulin Estrogen receptor beta Estrogen receptor Fibroblast growth factor 23 Fibroblast growth factor 9 Fibroblast growth factor receptor Fibroblast growth factor receptor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fms related receptor tyrosine kinase 3 ligand GRB2 associated binding protein 1 GRB2 associated binding protein 2 Growth factor receptor bound protein 2 Hepatocyte growth factor receptor Hepatocyte growth factor Immediate early response 3 Insulin receptor substrate 1 Insulin receptor substrate 2 Insulin Interleukin 1 receptor like 1 Interleukin-1 receptor-associated kinase 4 Kit ligand Klotho beta Klotho Mast/stem cell growth factor receptor Mitogen-activated protein kinase Mitogen-activated protein kinase Multifunctional fusion protein Myeloid differentiation primary response protein MyD88 Neuregulin 2 Neuregulin 3 Phosphatidylinositol 3-kinase regulatory subunit alpha isoform 2 Phosphatidylinositol 3-kinase regulatory subunit beta Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha isoform X5 Phosphatidylinositol 4-phosphate 5-kinase type-1 beta isoform X1 Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma isoform X5 Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha Phosphatidylinositol 5-phosphate 4-kinase type-2 beta Phosphoinositide-3-kinase adaptor protein 1 Platelet-derived growth factor receptor alpha Platelet-derived growth factor receptor beta Platelet-derived growth factor subunit A Platelet-derived growth factor subunit B Pro-epidermal growth factor Pro-neuregulin-1, membrane-bound isoform Proheparin-binding EGF-like growth factor Protein phosphatase 2 regulatory subunit B'gamma Protein phosphatase 2 scaffold subunit Abeta Proto-oncogene vav Rac family small GTPase 2 Ras homolog family member G Ras-related C3 botulinum toxin substrate 1 Receptor protein-tyrosine kinase Receptor protein-tyrosine kinase Receptor protein-tyrosine kinase Receptor protein-tyrosine kinase Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform Serine/threonine-protein phosphatase Striatin T-cell-specific surface glycoprotein CD28 TNF receptor-associated factor 6 Transforming growth factor alpha Tyrosine-protein kinase Fyn Tyrosine-protein kinase receptor Tyrosine-protein kinase Tyrosine-protein kinase Tyrosine-protein phosphatase non-receptor type non-specific serine/threonine protein kinase phosphatidylinositol-4,5-bisphosphate 3-kinase phosphatidylinositol-4,5-bisphosphate 3-kinase phosphatidylinositol-4,5-bisphosphate 3-kinase receptor protein-tyrosine kinase	A0A140TAK4 A0A286ZJM1 A0A286ZQX2 A0A286ZSM8 A0A287A231 A0A287A4F0 A0A287A6I2 A0A287A9P4 A0A287AAE4 A0A287ADF0 A0A287AFX3 A0A287APB4 A0A287AU44 A0A287AXR0 A0A287AYB4 A0A287AZM9 A0A287B3V5 A0A287B510 A0A287B5E0 A0A287B630 A0A287B726 A0A287B929 A0A287BCW9 A0A287BG34 A0A287BGB1 A0A287BGK8 A0A287BK67 A0A480ECT1 A0A480I421 A0A480J4F4 A0A480LMF4 A0A480NH74 A0A5G2QBP1 A0A5G2QNL8 A0A5G2QUY7 A0A5G2R1H6 A0A5G2R1K1 A0A5G2R7G2 A0A5G2RG05 A0A5K1UB41 A0A5K1UPW2 A0A8W4FI56 A0A8W4FMH5 A0A8X9AEI7 A1Y2K1 A7XUJ6 B6E241 F1RL75 F1RM38 F1RQR5 F1RSR6 F1RVI6 F1RWM5 F1RX68 F1RY78 F1RY80 F1RZU1 F1S2V7 F1S3B8 F1S4P0 F1S916 F1SB93 F1SCL0 F1SET9 F1SKR9 F1SLD3 F1SMG2 F1SRR6 F1SSQ9 F1SV94 F6Q7E6 I3L560 I3LG49 I3LKR6 I3LLF1 I3LR27 K7GMQ2 K7GMT0 K7GMU1 K7GPR7 K7GQJ1 P01315 P54612 P67776 Q01580 Q29040 Q2QLE0 Q95L12 Q9BDH4 Q9BE99	AREG BTC CD28 CD80 CD80/B7-1 CD86 DTR EGF EGFR ERBB2 ERBB3 ERBB4 EREG ESR ESR1 ESR2 FGF1 FGF10 FGF16 FGF18 FGF19 FGF2 FGF20 FGF22 FGF23 FGF3 FGF4 FGF5 FGF6 FGF8 FGF9 FGFR1 FGFR4 FLT3 FLT3LG FYN Fgf4 GAB1 GAB2 GRB2 HBEGF HEGFL HGF IER3 IL1RL1 INS INSR IRAK1 IRAK4 IRS1 IRS2 KIT KITLG KL KLB LCK MAPK1 MAPK3 MET MYD88 NR3A1 NRG1 NRG2 NRG3 PDGFA PDGFB PDGFRA PDGFRB PIK3AP1 PIK3CA PIK3CB PIK3CD PIK3R1 PIK3R2 PIP4K2A PIP4K2B PIP5K1A PIP5K1B PIP5K1C PPP2CA PPP2CB PPP2R1A PPP2R1B PPP2R5A PPP2R5B PPP2R5C PPP2R5D PTPN11 RAC1 RAC2 RHOG SRC STRN TGFA TRAF6 VAV1	Sus scrofa (pig)
PI3K/AKT Signaling	3-phosphoinositide-dependent protein kinase 1 Amphiregulin Betacellulin CD80 molecule CD86 molecule Epiregulin Estrogen receptor beta Estrogen receptor Fibroblast growth factor 23 Fibroblast growth factor 9 Fibroblast growth factor receptor Fibroblast growth factor receptor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fms related receptor tyrosine kinase 3 ligand GRB2 associated binding protein 1 GRB2 associated binding protein 2 Growth factor receptor bound protein 2 Hepatocyte growth factor receptor Hepatocyte growth factor Insulin receptor substrate 1 Insulin receptor substrate 2 Interleukin 1 receptor like 1 Interleukin-1 receptor-associated kinase 4 Kit ligand Klotho beta Klotho Mast/stem cell growth factor receptor Multifunctional fusion protein Myeloid differentiation primary response protein MyD88 Neuregulin 2 Neuregulin 3 Phosphatidylinositol 3-kinase regulatory subunit alpha isoform 2 Phosphatidylinositol 3-kinase regulatory subunit beta Phosphoinositide-3-kinase adaptor protein 1 Platelet-derived growth factor receptor alpha Platelet-derived growth factor receptor beta Platelet-derived growth factor subunit A Platelet-derived growth factor subunit B Pro-epidermal growth factor Pro-neuregulin-1, membrane-bound isoform Proheparin-binding EGF-like growth factor Proline rich 5 Proto-oncogene vav RPTOR independent companion of MTOR complex 2 Rac family small GTPase 2 Ras homolog family member G Ras-related C3 botulinum toxin substrate 1 Receptor protein-tyrosine kinase Receptor protein-tyrosine kinase Receptor protein-tyrosine kinase Receptor protein-tyrosine kinase Serine/threonine-protein kinase mTOR Striatin T-cell-specific surface glycoprotein CD28 TNF receptor-associated factor 6 Target of rapamycin complex subunit LST8 Transforming growth factor alpha Tyrosine-protein kinase Fyn Tyrosine-protein kinase Tyrosine-protein kinase Tyrosine-protein phosphatase non-receptor type non-specific serine/threonine protein kinase phosphatidylinositol-4,5-bisphosphate 3-kinase phosphatidylinositol-4,5-bisphosphate 3-kinase phosphatidylinositol-4,5-bisphosphate 3-kinase receptor protein-tyrosine kinase	A0A140TAK4 A0A286ZJM1 A0A286ZQX2 A0A286ZSM8 A0A286ZV67 A0A287A231 A0A287A6I2 A0A287A8R7 A0A287AAE4 A0A287ADF0 A0A287AFX3 A0A287AXR0 A0A287AYB4 A0A287AZM9 A0A287B3V5 A0A287B510 A0A287B5E0 A0A287B630 A0A287B726 A0A287B929 A0A287BCW9 A0A287BG34 A0A287BGK8 A0A287BK67 A0A480ECT1 A0A480J4F4 A0A480LMF4 A0A5G2QBP1 A0A5G2QNL8 A0A5G2QUY7 A0A5G2R1H6 A0A5G2R1K1 A0A5G2R7G2 A0A5K1UB41 A0A5K1UPW2 A0A8W4FI56 A0A8W4FMH5 A0A8X9AEI7 A1Y2K1 A7XUJ6 B6E241 F1RFA8 F1RHR8 F1RL75 F1RM38 F1RSR6 F1RWM5 F1RY78 F1RY80 F1RZU1 F1S3B8 F1S4P0 F1S916 F1SB93 F1SET9 F1SKR9 F1SLD3 F1SMG2 F1SRR6 F1SSQ9 F1SV94 F6Q7E6 I3L560 I3LEK8 I3LKR6 I3LLF1 I3LR27 K7GMT0 K7GMU1 K7GPR7 K7GQJ1 Q01580 Q29040 Q2QLE0 Q95L12 Q9BDH4 Q9BE99	AREG BTC CD28 CD80 CD80/B7-1 CD86 DTR EGF EGFR ERBB2 ERBB3 ERBB4 EREG ESR ESR1 ESR2 FGF1 FGF10 FGF16 FGF18 FGF19 FGF2 FGF20 FGF22 FGF23 FGF3 FGF4 FGF5 FGF6 FGF8 FGF9 FGFR1 FGFR4 FLT3 FLT3LG FYN Fgf4 GAB1 GAB2 GRB2 HBEGF HEGFL HGF IL1RL1 IRAK1 IRAK4 IRS1 IRS2 KIT KITLG KL KLB LCK MET MLST8 MTOR MYD88 NR3A1 NRG1 NRG2 NRG3 PDGFA PDGFB PDGFRA PDGFRB PDPK1 PIK3AP1 PIK3CA PIK3CB PIK3CD PIK3R1 PIK3R2 PRR5 PTPN11 RAC1 RAC2 RHOG RICTOR SRC STRN TGFA TRAF6 VAV1	Sus scrofa (pig)
GAB1 signalosome	Amphiregulin Betacellulin Epiregulin GRB2 associated binding protein 1 Growth factor receptor bound protein 2 Paxillin Phosphatidylinositol 3-kinase regulatory subunit alpha isoform 2 Phosphoprotein membrane anchor with glycosphingolipid microdomains 1 Pro-epidermal growth factor Proheparin-binding EGF-like growth factor Receptor protein-tyrosine kinase Transforming growth factor alpha Tyrosine-protein kinase Tyrosine-protein kinase Tyrosine-protein phosphatase non-receptor type phosphatidylinositol-4,5-bisphosphate 3-kinase	A0A287A231 A0A287A6I2 A0A287AZM9 A0A480LMF4 A0A5G2QBP1 A0A5G2RG25 A0A5K1UB41 B6E241 F1RXA1 F1SJ27 F1SKR9 F1SLD3 K7GMT0 K7GPR7 Q01580 Q9BDH4	AREG BTC CSK DTR EGF EGFR EREG GAB1 GRB2 HBEGF HEGFL PAG1 PIK3CA PIK3R1 PTPN11 PXN SRC TGFA	Sus scrofa (pig)
SHC1 events in EGFR signaling	Amphiregulin Betacellulin Epiregulin GTPase HRas GTPase NRas Growth factor receptor bound protein 2 Pro-epidermal growth factor Proheparin-binding EGF-like growth factor Receptor protein-tyrosine kinase SHC-transforming protein 1 SOS Ras/Rac guanine nucleotide exchange factor 1 Transforming growth factor alpha small monomeric GTPase	A0A286ZUQ0 A0A287A231 A0A287A6I2 A0A287AZM9 A0A5G2QBP1 A0A5G2QLX0 A0A5K1V5Y3 B6E241 F1SLD3 I3LCQ9 Q01580 Q2MJK3 Q9BDH4	AREG BTC DTR EGF EGFR EREG GRB2 HBEGF HEGFL HRAS KRAS NRAS SHC1 SOS1 TGFA	Sus scrofa (pig)
GRB2 events in EGFR signaling	Amphiregulin Betacellulin Epiregulin GTPase HRas GTPase NRas Growth factor receptor bound protein 2 Pro-epidermal growth factor Proheparin-binding EGF-like growth factor Receptor protein-tyrosine kinase SOS Ras/Rac guanine nucleotide exchange factor 1 Transforming growth factor alpha small monomeric GTPase	A0A286ZUQ0 A0A287A231 A0A287A6I2 A0A287AZM9 A0A5G2QBP1 A0A5G2QLX0 B6E241 F1SLD3 I3LCQ9 Q01580 Q2MJK3 Q9BDH4	AREG BTC DTR EGF EGFR EREG GRB2 HBEGF HEGFL HRAS KRAS NRAS SOS1 TGFA	Sus scrofa (pig)
EGFR interacts with phospholipase C-gamma	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma Amphiregulin Betacellulin Epiregulin Pro-epidermal growth factor Proheparin-binding EGF-like growth factor Receptor protein-tyrosine kinase Transforming growth factor alpha	A0A287A231 A0A287A6I2 A0A287AZM9 A0A5G2QBP1 F1SDV6 F1SLD3 Q01580 Q9BDH4	AREG BTC DTR EGF EGFR EREG HBEGF HEGFL PLCG1 TGFA	Sus scrofa (pig)
Cargo concentration in the ER	Amphiregulin CD59 glycoprotein CTAGE family member 5 isoform X2 Coagulation factor V Collagen type VII alpha 1 chain Cornichon family AMPA receptor auxiliary protein 1 Cornichon family AMPA receptor auxiliary protein 3 Folate receptor alpha Glutamate receptor Golgi SNAP receptor complex member 2 Lectin, mannose binding 1 like Lectin, mannose binding 1 Lectin, mannose binding 2 like Lectin, mannose binding 2 MIA SH3 domain ER export factor 3 Multiple coagulation factor deficiency 2, ER cargo receptor complex subunit Prolactin regulatory element-binding protein Protein transport protein SEC23 Protein transport protein Sec24B isoform a SEC24 homolog A, COPII coat complex component SEC24 homolog C, COPII coat complex component SEC24 homolog D, COPII coat complex component Serpin family A member 1 Small COPII coat GTPase SAR1B Transforming growth factor alpha Transmembrane emp24 domain-containing protein 10 Transmembrane p24 trafficking protein 2 Uteroferrin associated basic protein-2 cathepsin X	A0A286ZS63 A0A286ZV95 A0A287A6D5 A0A287AD28 A0A287ALA1 A0A287AWH7 A0A287BBV1 A0A287BLX2 A0A5G2QL94 A0A5G2QUR1 A0A8W4FFC7 A5GFX7 F1RPW2 F1S129 F1S155 F1S3D5 F1SCE4 F1SED4 F1SHL3 F1SJ28 F1SKM1 F1SLD3 F1SMS8 F1SU53 I3LJD2 K7GQY4 O62680 Q5PYH3 Q9BDH4	AREG CD59 CNIH1 CNIH3 COL7A1 CTSZ F5 FOLR1 FOLR3 GOSR2 GRIA1 LMAN1 LMAN1L LMAN2 LMAN2L MCFD2 MIA2 MIA3 PREB SAR1B SEC23A SEC24A SEC24B SEC24C SEC24D SERPINA1 TGFA TMED10 TMED2 UABP-2	Sus scrofa (pig)
trans-Golgi Network Vesicle Budding	ADP-ribosylation factor 1 Golgi brefeldin A resistant guanine nucleotide exchange factor 1 Synaptosomal-associated protein Syntaxin 4 Vesicle-associated membrane protein 2 Vesicle-associated membrane protein 8	A0A287AHK8 A0A5G2R276 A0A8W4F8A7 A0A8W4FA01 A0A8W4FPV1 F1RIR2	ARF1 GBF1 SNAP23 STX4 VAMP2 VAMP8	Sus scrofa (pig)
VxPx cargo-targeting to cilium	ADP-ribosylation factor ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 Cyclic nucleotide gated channel subunit alpha 4 Cyclic nucleotide gated channel subunit beta 1 Exocyst complex component 1 Exocyst complex component 2 Exocyst complex component 3 Exocyst complex component 5 Exocyst complex component 7 Exocyst complex component 8 Exocyst complex component Golgi brefeldin A resistant guanine nucleotide exchange factor 1 Polycystin 1, transient receptor potential channel interacting Polycystin-2 RAB11 family interacting protein 3 RAB3A interacting protein Ras-related protein Rab-11A Ras-related protein Rab-8A Rhodopsin	A0A286ZTQ8 A0A287A1M9 A0A287AA07 A0A287B229 A0A287B6N7 A0A287B8J6 A0A480IUJ5 A0A480TWJ1 A0A5G2QDG7 A0A8W4FPV1 F1RF40 F1RFB1 F1RMM3 F1RXP8 F1SH42 F2VYA1 F2Z5I8 O18766 Q52NJ1	ARF4 ASAP1 CNGA4 CNGB1 EXOC1 EXOC2 EXOC3 EXOC5 EXOC6 EXOC7 EXOC8 GBF1 PKD1 PKD2 RAB11 RAB11A RAB11FIP3 RAB3IP RAB8A RHO RHO1	Sus scrofa (pig)
MET receptor recycling	ADP-ribosylation factor 6 Adapter molecule crk GRB2 associated binding protein 1 Golgi associated, gamma adaptin ear containing, ARF binding protein 3 Growth factor receptor bound protein 2 Hepatocyte growth factor receptor Hepatocyte growth factor Ras-related protein Rab-4 Ras-related protein Rab-4	A0A286ZN77 A0A286ZTD8 A0A286ZXD1 A0A5G2QNF6 B6E241 F1SB93 K7GMT0 Q007T5 Q2QLE0	ARF6 CRK GAB1 GGA3 GRB2 HGF MET RAB4A RAB4B	Sus scrofa (pig)
RHOQ GTPase cycle	ADP ribosylation factor like GTPase 13B Amino acid transporter Anion exchange protein CDC42 effector protein 1 CDC42 effector protein 3 CDC42 effector protein 4 Caveolin Cdc42 effector protein 2 Cdc42-interacting protein 4 isoform 1 Cell division control protein 42 homolog Copine-8 Cystic fibrosis transmembrane conductance regulator DEP domain containing 1B Diaphanous related formin 3 E3 ubiquitin-protein ligase Formin binding protein 1 GIT ArfGAP 1 GIT ArfGAP 2 Gap junction protein Gfo/Idh/MocA-like oxidoreductase domain containing 1 Golgi associated PDZ and coiled-coil motif containing IQ motif containing GTPase activating protein 3 Intersectin 1 Junction plakoglobin Junction plakoglobin MAGUK p55 subfamily member 7 Oligophrenin-1 Phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 1 Pleckstrin homology and RhoGEF domain containing G3 Ragulator complex protein LAMTOR1 Ras homolog family member Q Ras-related protein Rab-7a Rho GTPase activating protein 17 Rho GTPase activating protein 1 Rho GTPase activating protein 21 Rho GTPase activating protein 33 Rho GTPase activating protein 5 Rho GTPase-activating protein 26 Rho GTPase-activating protein 35 Rho GTPase-activating protein 7 Rho guanine nucleotide exchange factor 7 Rho guanine nucleotide exchange factor 9 SLIT-ROBO Rho GTPase activating protein 2 STEAP3 metalloreductase Scribble planar cell polarity protein Stomatin Synapse defective Rho GTPase homolog 1 Synaptosomal-associated protein Transferrin receptor protein 1 Transferrin receptor protein 1 Vang-like protein Vesicle-associated membrane protein 3 WASP like actin nucleation promoting factor non-specific serine/threonine protein kinase non-specific serine/threonine protein kinase non-specific serine/threonine protein kinase non-specific serine/threonine protein kinase	A0A286ZI11 A0A286ZJQ9 A0A286ZMP2 A0A286ZPM4 A0A286ZUE0 A0A286ZYD7 A0A286ZZ96 A0A286ZZA8 A0A287A6H2 A0A287AHK8 A0A287AR23 A0A287AZG0 A0A287B310 A0A287B3E0 A0A287B7W3 A0A287BEC7 A0A287BSS5 A0A2C9F3E9 A0A480JSC9 A0A480P3R5 A0A481A732 A0A5G2QA45 A0A5G2QDP4 A0A5G2QFN5 A0A5G2QXS5 A0A5G2R661 A0A5G2RET7 A0A5K1VSS6 A0A5S6GXI4 A0A8W4FAC1 A0A8W4FMS3 A0A8W4FQG7 F1RJ64 F1RM07 F1RM08 F1RN87 F1RQV5 F1RV35 F1S4Q9 F1SAN7 F1SAW7 F1SEU3 F1SF43 F1SMK2 F1SQW0 I3L5H9 I3LAS2 I3LB11 I3LD06 I3LDR4 I3LG84 I3LIY8 I3LJN3 K9IWC9 Q007T2 Q8HZV3 Q8WNW3	ARHGAP1 ARHGAP17 ARHGAP21 ARHGAP26 ARHGAP33 ARHGAP35 ARHGAP5 ARHGEF7 ARHGEF9 ARL13B CAV1 CDC42 CDC42BPA CDC42BPB CDC42EP1 CDC42EP2 CDC42EP3 CDC42EP4 CFTR CPNE8 DEPDC1B DIAPH3 DLC1 FNBP1 GFOD1 GIT1 GIT2 GJA1 GOPC IQGAP3 ITSN1 JUP Jup LAMTOR1 MPP7 OPHN1 PAK1 PAK2 PLEKHG3 PREX1 RAB7A RHOQ SCRIB SLC1A5 SLC4A7 SNAP23 SRGAP2 STEAP3 STOM SYDE1 TFRC TRIP10 VAMP3 VANGL1 WASL WWP2	Sus scrofa (pig)
RND3 GTPase cycle	BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 1 BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 2 Carboxypeptidase D Caveolin Coiled-coil domain containing 88A Creatine kinase B-type Cytoskeleton associated protein 4 DEP domain containing 1B Desmoglein 1 Desmoglein-1 Desmoplakin Discs large MAGUK scaffold protein 5 Dystonin Family with sequence similarity 83 member B Flotillin Kinectin 1 Mucin 13, cell surface associated Nischarin Phosphatidylinositol 3-kinase regulatory subunit alpha isoform 2 Phosphatidylinositol 3-kinase regulatory subunit beta Phosphatidylinositol binding clathrin assembly protein Plakophilin 4 Pleckstrin homology and RhoGEF domain containing G5 RAS protein activator like 2 RNA binding motif protein 39 Rho GTPase activating protein 21 Rho GTPase activating protein 5 Rho GTPase-activating protein 35 Rho-associated protein kinase Rho-related GTP-binding protein RhoE Scribble planar cell polarity protein Ssemaphorin 4F Thioredoxin like 1 Tropomodulin 3 Tyrosine-protein phosphatase non-receptor type 13 UBX domain protein 11 Uncharacterized protein Vang-like protein Vang-like protein receptor protein-tyrosine kinase tRNA (34-2'-O)-methyltransferase regulator WDR6	A0A286ZJQ9 A0A286ZM17 A0A286ZPP2 A0A287AH84 A0A287AIV8 A0A287ALN0 A0A287B402 A0A287B7U3 A0A287BAQ0 A0A287BCT3 A0A287BKB6 A0A287BQA2 A0A287BS05 A0A480JZF5 A0A5G2QA45 A0A5G2QIS7 A0A5G2R425 A0A5G2R4N6 A0A5G2RAI6 A0A5G2RKR1 A0A8W4FAC1 F1RJY3 F1RM07 F1RN68 F1RW75 F1RZW2 F1S1X9 F1S916 F1SAW7 F1SKR9 F1SPP8 F1SQ58 F1SSN5 F1SUT8 I3LA65 I3LD06 I3LDR4 I3LM60 I3LMD8 I3LPB5 Q3BDI7	ARHGAP21 ARHGAP35 ARHGAP5 CAV1 CCDC88A CKAP4 CKB CPD DEPDC1B DLG5 DSG1 DSP DST EPHA2 FAM83B FLOT2 KCTD13 KTN1 LOC100516390 MUC13 NISCH PICALM PIK3R1 PIK3R2 PKP4 PLEKHG5 PTPN13 RASAL2 RBM39 RND3 ROCK1 SCRIB SEMA4F TMOD3 TNFAIP1 TXNL1 UBXN11 VANGL1 VANGL2 WDR6	Sus scrofa (pig)
Sema4D mediated inhibition of cell attachment and migration	Hepatocyte growth factor receptor Plexin B1 RAS related Ras-related C3 botulinum toxin substrate 1 Rho GTPase-activating protein 35 Semaphorin 4D Transforming protein RhoA	A0A5K1TV69 A0A8W4FI56 F1RHW4 F1RM07 F1SLI0 I3LVS7 Q2QLE0	ARHGAP35 MET PLXNB1 RAC1 RHOA RRAS SEMA4D	Sus scrofa (pig)
RHOH GTPase cycle	Amino acid transporter Anion exchange protein Caveolin Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex Family with sequence similarity 91 member A1 Junction plakoglobin Junction plakoglobin Methionine synthase NSFL1 cofactor p47 Nipsnap homolog 2 Ragulator complex protein LAMTOR1 Ral GTPase activating protein catalytic subunit alpha 1 Ras homolog family member H Ras-related protein Rab-7a Rho GDP dissociation inhibitor gamma Rho GDP-dissociation inhibitor 1 Rho-associated protein kinase 2 Rho-associated protein kinase Stomatin Transferrin receptor protein 1 Transferrin receptor protein 1 Transmembrane protein 59 Tubulin alpha-1B chain Tyrosine-protein kinase Tyrosine-protein kinase Uveal autoantigen with coiled-coil domains and ankyrin repeats Vang-like protein Vesicle-associated membrane protein 3 WD repeat domain 11 non-specific serine/threonine protein kinase non-specific serine/threonine protein kinase non-specific serine/threonine protein kinase non-specific serine/threonine protein kinase	A0A286ZI11 A0A286ZJP1 A0A286ZJQ9 A0A286ZMP2 A0A286ZTN4 A0A287B310 A0A287B7Y7 A0A287BEC7 A0A287BEY0 A0A287BPQ3 A0A2C9F3E9 A0A5G2QAH7 A0A5G2QFH7 A0A5G2QIS7 A0A5G2QMU0 A0A5G2R8G1 A0A5G2RET7 A0A5K1VSS6 A0A5S6GXI4 E7EI20 F1RHM1 F1RM08 F1SAW7 F1SJ27 F1SQW0 F1SV94 I3LR07 I3LRS0 M3TYT0 Q2F7Z7 Q2XVP4 Q8HZV3 Q8WNW3	ARHGDIA ARHGDIG CAV1 CSK DBT FAM91A1 JUP Jup LAMTOR1 LCK MTR NIPSNAP2 NSFL1C PAK1 PAK2 PAK5 PAK6 RAB7A RALGAPA1 RHOH ROCK1 ROCK2 SLC1A5 SLC4A7 STOM TFRC TMEM59 TUBA1B UACA VAMP3 VANGL1 WDR11	Sus scrofa (pig)
TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)	Cingulin E3 ubiquitin-protein ligase Junctional adhesion molecule A Par-3 family cell polarity regulator Par-6 family cell polarity regulator alpha Polyubiquitin-C Rho/Rac guanine nucleotide exchange factor 18 Serine/threonine-protein kinase receptor TGF-beta receptor type-1 Transforming growth factor beta-1 proprotein Transforming protein RhoA Ubiquitin B Ubiquitin C Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein protein kinase C	A0A286ZZ01 A0A287A1S5 A0A287AXZ5 A0A287AZA7 A0A287BLR9 A0A2C9F3G2 A0A5G2QMD9 A0A5G2QYR6 A0A5G2RC56 A7U5U2 F1S911 I3LTD6 I3LU84 I3LVS7 P07200 P0CG68	ARHGEF18 CGN F11R PARD3 PARD6A PRKCZ RHOA RPS27A SMURF1 TGFB1 TGFBR1 TGFBR2 UBA52 UBB UBC	Sus scrofa (pig)
Glycosphingolipid catabolism	Alpha-galactosidase Arylsulfatase A Arylsulfatase B Arylsulfatase D Arylsulfatase E (chondrodysplasia punctata 1) Arylsulfatase G Arylsulfatase K Arylsulfatase family member I Arylsulfatase family member J Beta-galactosidase Beta-galactosidase Beta-galactosidase Beta-hexosaminidase Beta-hexosaminidase Carboxypeptidase Ectonucleotide pyrophosphatase/phosphodiesterase 7 Galactocerebrosidase Galactosidase beta 1 like Ganglioside GM2 activator Glucosylceramidase beta 3 Mannose-6-phosphate receptor, cation dependent Neutral ceramidase Non-lysosomal glucosylceramidase Prosaposin Sialidase-1 Sphingomyelin phosphodiesterase 4 Sphingomyelin phosphodiesterase Sulfatase N-terminal domain-containing protein Sulfatase N-terminal domain-containing protein Sulfatase N-terminal domain-containing protein Sulfatase modifying factor 1 Sulfatase modifying factor 2 ceramidase exo-alpha-sialidase exo-alpha-sialidase exo-alpha-sialidase sphingomyelin phosphodiesterase sphingomyelin phosphodiesterase	A0A286ZR19 A0A286ZRI8 A0A286ZTV6 A0A287A0M2 A0A287A7V3 A0A287AGF2 A0A287AXH1 A0A287B239 A0A287B636 A0A287BP79 A0A480LAY6 A0A480QKC9 A0A5G2Q9X4 A0A5G2QVV6 A0A5G2QXG4 A0A5G2QXL0 A0A5G2R907 A0A5G2R9H5 A5PF10 D0G6X8 F1REY9 F1RIU4 F1RK95 F1RL69 F1RMN6 F1RSY4 F1RZ75 F1S048 F1SDZ2 F1SES5 F1SLX0 F1SM45 F1SR82 F1STB6 I3LGI9 I3LM95 I3LRN8 I3LS26	ARSA ARSB ARSD ARSG ARSI ARSJ ARSK ARSL ASAH1 ASAH2 CTSA ENPP7 GALC GBA2 GBA3 GLA GLB1 GLB1L GLB1L2 GLB1L3 GM2A HEXA HEXB LOC100621771 M6PR NEU1 NEU2 NEU3 NEU4 PSAP SMPD1 SMPD2 SMPD3 SMPD4 STS SUMF1 SUMF2	Sus scrofa (pig)	G09546QO G27025MB G58161NS
CS/DS degradation	Alpha-L-iduronidase Arylsulfatase B Beta-hexosaminidase Beta-hexosaminidase Biglycan Brevican core protein Chondroitin sulfate proteoglycan 4 Chondroitin sulfate proteoglycan 5 Decorin Hyaluronidase Iduronate 2-sulfatase Neurocan Versican core protein	A0A286ZRI8 A0A287A7V3 A0A287AHN9 A0A287AIY6 A0A287BS38 A0A5G2RB02 A0A5K1UKC5 A0A8W4FKJ8 D0G6X8 F1REZ2 F1SJ86 F1SPN9 M3VHA3	ARSB BCAN BGN CSPG4 CSPG5 DCN HEXA HEXB HYAL1 IDS IDUA NCAN VCAN	Sus scrofa (pig)	G27025MB
RET signaling	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma Artemin Cell division cycle 25C Docking protein 1 Docking protein 2 Docking protein 4 Docking protein 5 Docking protein 6 GDNF family receptor alpha 1 GDNF family receptor alpha 4 GDNF family receptor alpha-2 GRB2 associated binding protein 1 GRB2 associated binding protein 2 Glial cell derived neurotrophic factor Growth factor receptor bound protein 2 Growth factor receptor bound protein 7 Growth factor receptor-bound protein 10 Insulin receptor substrate 2 Mitogen-activated protein kinase Neurturin PDZ and LIM domain protein 7 Persephin Phosphatidylinositol 3-kinase regulatory subunit alpha isoform 2 Phosphatidylinositol 3-kinase regulatory subunit beta Protein kinase C Proto-oncogene tyrosine-protein kinase receptor Ret RAP1 GTPase activating protein SHC adaptor protein 3 SHC-transforming protein 1 SOS Ras/Rac guanine nucleotide exchange factor 1 Tyrosine-protein kinase Tyrosine-protein phosphatase non-receptor type phosphatidylinositol-4,5-bisphosphate 3-kinase phosphatidylinositol-4,5-bisphosphate 3-kinase phosphatidylinositol-4,5-bisphosphate 3-kinase	A0A286ZUQ0 A0A287ADY7 A0A287AY39 A0A287B5X0 A0A287B630 A0A287B726 A0A287B731 A0A287BDL2 A0A287BEY5 A0A480LMF4 A0A5G2QY14 A0A5K1UB41 A0A5K1UPW2 A0A5K1V5Y3 A0A8W4F937 A0A8W4FLI0 A0A8X9AEI7 A5GFP8 B5KFD7 B6E241 F1RG22 F1RH78 F1RMC2 F1RMZ6 F1RV14 F1RX94 F1S916 F1SBT4 F1SDV6 F1SKR9 F1SNV8 I3L7P2 K7GMT0 K7GPR7 M3VH78	ARTN CDC25C DOK1 DOK2 DOK4 DOK5 DOK6 GAB1 GAB2 GDNF GFRA1 GFRA2 GFRA3 GFRA4 GRB2 GRB7 Grb10 IRS2 MAPK7 NRTN PDLIM7 PIK3CA PIK3CB PIK3CD PIK3R1 PIK3R2 PLCG1 PRKCA PSPN PTPN11 RAP1GAP RET SHC1 SHC3 SOS1 SRC	Sus scrofa (pig)
Asparagine N-linked glycosylation	Asialoglycoprotein receptor 1 Asialoglycoprotein receptor 2 Glycosyltransferase 2-like domain-containing protein Uromodulin	A0A5G2Q826 A0A5G2QNB6 F1RPA9 I3L7N4	ASGR1 ASGR2 LOC110255214 UMOD	Sus scrofa (pig)
TFAP2 (AP-2) family regulates transcription of growth factors and their receptors	ATPase family AAA domain containing 2 Estrogen receptor Glycoprotein hormones alpha chain Lutropin subunit beta	A0A287AQ37 P01219 P01232 Q29040	ATAD2 CGA ESR ESR1 LHB NR3A1	Sus scrofa (pig)
Cilium Assembly	Alpha-tubulin N-acetyltransferase 1 Histone deacetylase 6	A0A287BPX4 I3L925	ATAT1 HDAC6 MEC17	Sus scrofa (pig)
Ion transport by P-type ATPases	ATPase 13A1 ATPase Na+/K+ transporting subunit alpha 3 ATPase cation transporting 13A2 Calcium-transporting ATPase Calcium-transporting ATPase Calcium-transporting ATPase Calcium-transporting ATPase Calcium-transporting ATPase Calcium-transporting ATPase Calcium-transporting ATPase Calcium/calmodulin-dependent protein kinase type II subunit delta Calmodulin 3 Cardiac phospholamban Cation-transporting ATPase Cation-transporting ATPase FXYD domain-containing ion transport regulator P-type Cu(+) transporter PDZ domain-containing protein 11 Phospholemman Phospholipid-transporting ATPase Phospholipid-transporting ATPase Phospholipid-transporting ATPase Phospholipid-transporting ATPase Phospholipid-transporting ATPase Phospholipid-transporting ATPase Phospholipid-transporting ATPase Phospholipid-transporting ATPase Phospholipid-transporting ATPase Phospholipid-transporting ATPase Phospholipid-transporting ATPase Phospholipid-transporting ATPase Phospholipid-transporting ATPase Phospholipid-transporting ATPase Potassium-transporting ATPase subunit beta Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 Sarcoplasmic/endoplasmic reticulum calcium ATPase 3 Sodium/potassium-transporting ATPase subunit alpha-2 Sodium/potassium-transporting ATPase subunit alpha Sodium/potassium-transporting ATPase subunit alpha Sodium/potassium-transporting ATPase subunit beta-1 Sodium/potassium-transporting ATPase subunit beta Sodium/potassium-transporting ATPase subunit beta Sorcin calcium/calmodulin-dependent protein kinase calcium/calmodulin-dependent protein kinase calcium/calmodulin-dependent protein kinase	A0A287A226 A0A287AFK3 A0A287AL21 A0A287APC7 A0A287B705 A0A287B7D1 A0A287B7S6 A0A287BAN5 A0A287BCC5 A0A5G2Q8V3 A0A5G2QCQ9 A0A5G2QQF7 A0A5G2QSB0 A0A5G2QWK6 A0A5G2RAC3 A0A5G2RDL8 A0A5K1U0J0 A0A5K1VCX5 A0A8W4FK37 A0A8W4FN13 A0A8X9AEX2 D2WKD8 F1RL74 F1RM59 F1RQ73 F1S340 F1S3S6 F1SDH8 F1SFG8 F1SM35 F1SNN7 F1SQH3 F1ST41 F1SUR9 I3LIK9 I3LMB3 I3LN55 I3LUR3 K7GQ24 O77696 P05027 P11607 P18434 P61013 Q6QA76 Q95266	ATP10A ATP10B ATP10D ATP11A ATP11B ATP11C ATP12A ATP13A1 ATP13A2 ATP13A4 ATP13A5 ATP1A2 ATP1A3 ATP1B1 ATP1B2 ATP1B3 ATP2A1 ATP2A2 ATP2A3 ATP2B1 ATP2B2 ATP2B3 ATP2B4 ATP2C1 ATP2C2 ATP4A ATP4B ATP7A ATP8A1 ATP8A2 ATP8B1 ATP8B2 ATP8B3 ATP8B4 ATP9A ATP9B CALM3 CAMK2A CAMK2B CAMK2D CAMK2G FXYD1 FXYD6 PDZD11 PDZK11 PLM PLN SRI	Sus scrofa (pig)
Basigin interactions	Asc-type amino acid transporter 1 Basigin Caveolin Cystine/glutamate transporter Integrin beta Integrin subunit alpha 3 Integrin subunit alpha 6 Interstitial collagenase Large neutral amino acids transporter small subunit 1 Large neutral amino acids transporter small subunit 2 Myelin associated glycoprotein Peptidyl-prolyl cis-trans isomerase A RING-type E3 ubiquitin transferase Sialophorin Sodium/potassium-transporting ATPase subunit beta-1 Sodium/potassium-transporting ATPase subunit beta Sodium/potassium-transporting ATPase subunit beta Solute carrier family 16 member 3 Solute carrier family 16 member 8 Solute carrier family 3 member 2 Solute carrier family 7 (Amino acid transporter light chain, y+L system), member 7 tv3 Solute carrier family 7 member 9	A0A286ZJQ9 A0A286ZQH4 A0A287AAH2 A0A287AMY7 A0A287BAN5 A0A5G2QGZ8 A0A5G2QRY2 A0A5G2R2T5 A0A8W4FC88 A8HG48 F1RNW8 F1RT62 F1ST41 I3L6F7 I3LQ25 I3LQW3 K7GQ83 K9IVK6 K9J6I4 P05027 P21692 P62936	ATP1B1 ATP1B2 ATP1B3 BSG CAV1 ITGA3 ITGA6 ITGB1 MAG MMP1 PPIA PPIL2 SLC16A3 SLC16A8 SLC3A2 SLC7A10 SLC7A11 SLC7A5 SLC7A7 SLC7A8 SLC7A9 SPN	Sus scrofa (pig)
Formation of ATP by chemiosmotic coupling	ATP synthase F1 subunit epsilon ATP synthase lipid-binding protein ATP synthase lipid-binding protein ATP synthase lipid-binding protein ATP synthase protein 8 ATP synthase subunit O, mitochondrial ATP synthase subunit a ATP synthase subunit alpha, mitochondrial ATP synthase subunit beta ATP synthase subunit e, mitochondrial ATP synthase subunit f, mitochondrial ATP synthase subunit gamma ATP synthase subunit s, mitochondrial isoform X1 ATP synthase subunit	A0A286ZIA7 A0A286ZRY7 A0A287BN31 A0A8W4F7C1 A0A8W4FI02 A0A8X9AEI6 K7GLT8 K7GS22 P80021 Q2EN81 Q35914 Q35915 Q95339 Q9MYT8	ATP5A1 ATP5A2 ATP5F1A ATP5F1B ATP5F1C ATP5F1E ATP5I ATP5J2 ATP5MC2 ATP5MC3 ATP5ME ATP5MF ATP5O ATP5PO ATP6 ATP8 ATPASE6 ATPASE8 DMAC2L LOC100519871 MT-ATP6 MT-ATP8 MTATP6 MTATP8	Sus scrofa (pig)

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