GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	March 20, 2024
ECODAB	April 1, 2019

Displaying entries **151 - 175** of **360** in total

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Pathway Name	Protein Name	UniProt ID	Gene Symbol	Organism
Costimulation by the CD28 family	Ig-like domain-containing protein Phosphatidylinositol 3-kinase regulatory subunit alpha isoform 2 Phosphatidylinositol 3-kinase regulatory subunit beta phosphatidylinositol-4,5-bisphosphate 3-kinase	A0A5G2QMX5 A0A5K1UB41 F1S916 F1SKR9	ICOSLG PIK3CA PIK3R1 PIK3R2	Sus scrofa (pig)
MyD88-independent TLR4 cascade	Lymphocyte antigen 96 Monocyte differentiation antigen CD14 TIR domain-containing adapter molecule 1 TIR domain-containing adapter molecule 2 Toll-like receptor 4	A0A287BMU9 A0A480K9W0 A2SW51 A7BG67 K9J6H0	CD14 LY96 TICAM1 TICAM2 TLR4	Sus scrofa (pig)
MyD88:MAL(TIRAP) cascade initiated on plasma membrane	Evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial Mitogen-activated protein kinase kinase kinase 1 TNF receptor-associated factor 6 Toll/interleukin-1 receptor domain-containing adapter protein	A0A287A8A9 A0A287ABQ5 A7XUJ6 F1SA28	ECSIT MAP3K1 TIRAP TRAF6	Sus scrofa (pig)
Keratan sulfate biosynthesis	Aggrecan core protein Alpha2,3-sialyltransferase Beta-1,4-galactosyltransferase 5 Beta-1,4-galactosyltransferase Beta-1,4-galactosyltransferase Beta-1,4-galactosyltransferase Beta-1,4-galactosyltransferase Beta-1,4-galactosyltransferase Beta-1,4-glucuronyltransferase 1 CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 1 CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 4 isoform 4 Fibromodulin Gal-NAc6S Hexosyltransferase Hexosyltransferase Hexosyltransferase Keratocan Lumican Mimecan Osteomodulin Prolargin Solute carrier family 35 member D2 Sulfotransferase Sulfotransferase Sulfotransferase Type 2 lactosamine alpha-2,3-sialyltransferase	A0A0H5ANC0 A0A1S6M251 A0A287A537 A0A287AMU7 A0A287B863 A0A287BFE7 A0A287BG16 A0A287BJP1 A0A287BKI9 A0A5G2QU42 F1RRV7 F1RUS9 F1S1A6 F1S454 F1S6B4 F1S6B5 F1S6H2 F1SHJ6 F1SIW5 F1SPA3 F1SQ08 F1SQ09 F1SUE2 I3L6A5 I3LK83 Q70D54	ACAN B3GNT2 B3GNT4 B3GNT7 B4GALT1 B4GALT2 B4GALT3 B4GALT4 B4GALT5 B4GALT6 B4GAT1 CHST1 CHST2 FMOD KERA LOC100522551 LUM OGN OMD PRELP SLC35D2 ST3GAL-III ST3GAL1 ST3GAL2 ST3GAL3 ST3GAL4 ST3GAL6	Sus scrofa (pig)
Retinoid metabolism and transport	Agrin Aldo-keto reductase family 1 member C1 Apolipoprotein A-I Apolipoprotein A-II Apolipoprotein A-IV Apolipoprotein B Apolipoprotein C-II Apolipoprotein C-III Apolipoprotein E Apolipoprotein M Beta-carotene oxygenase 1 Carotenoid-cleaving dioxygenase, mitochondrial Colipase Glypican 2 Glypican 4 Glypican 5 Glypican-1 Glypican-3 Glypican-6 LDL receptor related protein 10 LDL receptor related protein 12 LDL receptor related protein 8 Lecithin retinol acyltransferase Lipoprotein lipase Phospholipase B1, membrane-associated Putative aldo-keto reductase family 1 member C2 Retinol binding protein 1 Retinol binding protein 2 Retinol dehydrogenase 11 Retinol-binding protein Syndecan-4 Syndecan Syndecan Syndecan Transthyretin Transthyretin Triacylglycerol lipase	A0A286ZPB0 A0A286ZQC7 A0A286ZS39 A0A286ZXB4 A0A287AG13 A0A287AJ15 A0A287ATH4 A0A287AW22 A0A287B0A0 A0A287B286 A0A287BCU5 A0A287BM29 A0A480K0L3 A0A480KVF0 A0A480YJR0 A0A481BCM9 A0A5G2QEH1 A0A5G2QIE9 A0A5G2QTV7 A0A5G2RI58 A0A5G2RJR8 E7CXS0 F1RM45 F1RNM8 F1RTE1 F1RYR6 F1S0L5 F1SA24 F1SC80 F6PSJ3 K7GNF5 K7GQ93 P02703 P27917 P50390 Q2LE37 Q8HZJ6	AGRN AKR1C1 AKR1C2 APOA1 APOA2 APOA4 APOB APOC2 APOC3 APOE APOM ApoER2 BCO1 BCO2 CLPS GPC1 GPC2 GPC3 GPC4 GPC5 GPC6 LPL LRAT LRP10 LRP12 LRP8 PLB1 PNLIP RBP1 RBP2 RBP4 RDH11 SDC1 SDC2 SDC3 SDC4 TTR	Sus scrofa (pig)
Apoptotic execution phase	B-cell receptor-associated protein Caspase-8 Dynamin-1-like protein non-specific serine/threonine protein kinase	A0A287B0C4 A0A287BMW9 F1S2A8 Q56VC3	BCAP31 CASP8 DNM1L STK24	Sus scrofa (pig)
Negative regulation of MET activity	E3 ubiquitin-protein ligase CBL Endophilin-A2 Epidermal growth factor receptor pathway substrate 15 Growth factor receptor bound protein 2 Hepatocyte growth factor receptor Hepatocyte growth factor-regulated tyrosine kinase substrate Hepatocyte growth factor Leucine rich repeats and immunoglobulin like domains 1 Polyubiquitin-C SH3 domain containing GRB2 like 3, endophilin A3 SH3 domain containing kinase binding protein 1 Signal transducing adaptor molecule 2 Signal transducing adaptor molecule Tyrosine-protein phosphatase non-receptor type Tyrosine-protein phosphatase non-receptor type Ubiquitin B Ubiquitin C Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein ubiquitinyl hydrolase 1	A0A286ZQE1 A0A287A000 A0A287AZA7 A0A287BAQ6 A0A287BNZ9 A0A2C9F3G2 A0A5G2Q9Y0 A0A5G2QFX7 A0A5G2RE13 A7U5U2 B6E241 F1RYL9 F1S7L8 F1S911 F1SB93 F1SFR8 F1SHW8 I3LPZ5 P0CG68 Q2QLE0	CBL EPS15 GRB2 HGF HGS LRIG1 MET PTPN1 PTPN2 RPS27A SH3GL1 SH3GL3 SH3KBP1 STAM STAM2 UBA52 UBB UBC USP8	Sus scrofa (pig)
Trafficking and processing of endosomal TLR	Cathepsin B Cathepsin K Cathepsin L Endoplasmin Legumain Procathepsin L Protein canopy homolog 3 Toll like receptor 7 Toll like receptor 8 Toll-like receptor 9 Unc-93 homolog B1, TLR signaling regulator	A0A287AFA5 A0A288CG39 A0A5G2QDA1 A0A5G2QE64 A0A8W4FL93 A1E295 A5GFQ5 F1S4J6 Q28944 Q5I2M3 Q9GLE3	CNPY3 CTSB CTSK CTSL CTSL1 HSP90B1 LGMN TLR7 TLR8 TLR9 TNRC5 UNC93B1	Sus scrofa (pig)
Golgi Associated Vesicle Biogenesis	ADP-ribosylation factor 1 AP complex subunit beta AP complex subunit beta AP complex subunit sigma AP complex subunit sigma AP-1 complex subunit gamma AP-1 complex subunit mu-1 AP-1 complex subunit mu-2 AP-3 complex subunit beta Acyl-CoA binding domain containing 3 Adaptin ear-binding coat-associated protein 1 Adaptor related protein complex 3 subunit sigma 1 Adaptor related protein complex 4 subunit epsilon 1 Beta-arrestin-1 Biogenesis of lysosome-related organelles complex 1 subunit 3 Biogenesis of lysosome-related organelles complex 1 subunit 6 Carboxypeptidase D Clathrin heavy chain Clathrin light chain Cyclin G associated kinase Dystrobrevin binding protein 1 Golgin B1 Huntingtin interacting protein 1 related Insulin like growth factor 2 receptor NSF attachment protein alpha Phosphatidylinositol binding clathrin assembly protein Phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 alpha Protein YIPF SNARE-associated protein Snapin Sortilin 1 Sorting nexin-2 Sorting nexin Sorting nexin TBC1 domain family member 8B TPD52 like 1 Thioredoxin domain containing 5 Trans-Golgi network integral membrane protein 2 Transferrin receptor protein 1 Transferrin receptor protein 1 Tumor protein D52 Vesicle-associated membrane protein 2 Vesicle-associated membrane protein 8 dynamin GTPase phosphoinositide 5-phosphatase	A0A286ZND1 A0A286ZSA0 A0A286ZUD5 A0A287A638 A0A287A682 A0A287A8E1 A0A287ARZ1 A0A287B8X7 A0A287BMK7 A0A287BPZ4 A0A5G2QCF0 A0A5G2QG20 A0A5G2QNT7 A0A5G2QQ26 A0A5G2QSL5 A0A5G2QSN6 A0A5G2QTU8 A0A5G2QW16 A0A5G2R276 A0A5G2RAI6 A0A5G2RCK3 A0A5S6GXI4 A0A8W4F8A7 A0A8W4FA01 A0A8W4FAA6 A5A769 A5A778 F1REX8 F1RFI2 F1RN68 F1RX99 F1RYM9 F1RZ19 F1S2G1 F1S3C7 F1SB67 F1SBI1 F1SBR2 F1SQ16 I3LE99 I3LLX2 I3LPF1 K7GLS0 Q8HZV3	ACBD3 AP1B1 AP1G1 AP1M1 AP1M2 AP1S1 AP1S3 AP3B1 AP3S1 AP4B1 AP4E1 ARF1 ARRB1 BLOC1S3 BLOC1S6 CLTA CLTC CPD DNM2 DTNBP1 GAK GOLGB1 HIP1R IGF2R NAPA NECAP1 OCRL PICALM PIK3C2A PLDN SNAPIN SNX2 SNX5 SNX9 SORT1 TBC1D8B TFRC TPD52 TPD52L1 TXNDC5 VAMP2 VAMP8 YIPF6	Sus scrofa (pig)
Signaling by Activin	Inhibin alpha chain Inhibin beta A chain Inhibin beta B chain Mitogen-activated protein kinase Mitogen-activated protein kinase Mothers against decapentaplegic homolog 3 Mothers against decapentaplegic homolog 4 Mothers against decapentaplegic homolog Serine/threonine-protein kinase receptor Serine/threonine-protein kinase receptor Transforming growth factor beta receptor 3 receptor protein serine/threonine kinase receptor protein serine/threonine kinase	A0A287AAP7 A0A287BE69 A0A287BJX6 A0A287BPF5 A0A287BPI7 A0A480NH74 A0A5G2RG05 A0A5K1U747 F1S0H6 P03970 P04087 P84024 Q9GKQ9	ACVR1B ACVR1C ACVR2A ACVR2B INHA INHBA INHBB MADH3 MADH4 MAPK1 MAPK3 SMAD2 SMAD3 SMAD4 TGFBR3	Sus scrofa (pig)
PI Metabolism	Tumor necrosis factor alpha-induced protein 8-like protein 2	F1SSY0	TNFAIP8L2	Sus scrofa (pig)
GAB1 signalosome	Amphiregulin Betacellulin Epiregulin GRB2 associated binding protein 1 Growth factor receptor bound protein 2 Paxillin Phosphatidylinositol 3-kinase regulatory subunit alpha isoform 2 Phosphoprotein membrane anchor with glycosphingolipid microdomains 1 Pro-epidermal growth factor Proheparin-binding EGF-like growth factor Receptor protein-tyrosine kinase Transforming growth factor alpha Tyrosine-protein kinase Tyrosine-protein kinase Tyrosine-protein phosphatase non-receptor type phosphatidylinositol-4,5-bisphosphate 3-kinase	A0A287A231 A0A287A6I2 A0A287AZM9 A0A480LMF4 A0A5G2QBP1 A0A5G2RG25 A0A5K1UB41 B6E241 F1RXA1 F1SJ27 F1SKR9 F1SLD3 K7GMT0 K7GPR7 Q01580 Q9BDH4	AREG BTC CSK DTR EGF EGFR EREG GAB1 GRB2 HBEGF HEGFL PAG1 PIK3CA PIK3R1 PTPN11 PXN SRC TGFA	Sus scrofa (pig)
APAP ADME	ABC-type glutathione-S-conjugate transporter ABC-type glutathione-S-conjugate transporter ATP binding cassette subfamily C member 5 Aminoacylase-1 Broad substrate specificity ATP-binding cassette transporter ABCG2 Broad substrate specificity ATP-binding cassette transporter ABCG2 Cystic fibrosis transmembrane conductance regulator Cytochrome P450 2E1 Cytosolic non-specific dipeptidase Gamma-glutamyltransferase 6 Glutathione hydrolase Glutathione hydrolase Multidrug resistance-associated protein 1 Sulfotransferase Sulfotransferase Sulfotransferase Sulfotransferase UDP-glucuronosyltransferase UDP-glucuronosyltransferase UDP-glucuronosyltransferase UDP-glucuronosyltransferase arylamine N-acetyltransferase arylamine N-acetyltransferase glucuronosyltransferase glucuronosyltransferase glutathione transferase glutathione transferase	A0A286ZRB6 A0A286ZW98 A0A287A3B9 A0A287ABK7 A0A287AY60 A0A287BBR6 A0A480QK70 A0A480RQR3 A0A5G2QMB0 A0A5G2R0Q5 A0A5G2R2F8 A0A5G2R606 A0A5K1UGB8 A0A5S6GWJ4 A0A8W4F6U6 A0A8W4FC10 A0A8W4FI10 A0A8X9AEU1 F1RL37 F1S4Y1 F1S8V9 F1SNL7 I3LC84 I3LLX8 P37111 Q3S3F7 Q8MIB3	ABCC1 ABCC2 ABCC3 ABCC4 ABCC5 ABCG2 ABCG2A ACY1 BMDP CNDP2 CYP2E1 GGT1 GGT6 GGT7 GSTT1 LOC100153094 LOC100511540 LOC100515741 LOC100516628 LOC100623255 LOC100623504 LOC100739163 LOC110262115 SULT1A3 SULT1C4 SULT1E1 SULT2A1 UGT2B31	Sus scrofa (pig)
Heme biosynthesis	5-aminolevulinate synthase 5-aminolevulinate synthase Albumin Broad substrate specificity ATP-binding cassette transporter ABCG2 Broad substrate specificity ATP-binding cassette transporter ABCG2 Cytochrome c oxidase assembly homolog COX15 Delta-aminolevulinic acid dehydratase FLVCR heme transporter 1 Ferrochelatase Protoheme IX farnesyltransferase, mitochondrial Protoporphyrinogen oxidase Uroporphyrinogen decarboxylase coproporphyrinogen oxidase hydroxymethylbilane synthase uroporphyrinogen-III synthase	A0A287B3T2 A0A287BAY9 A0A287BGW4 A0A5S6GWJ4 A0SNU8 F1RUD4 F1S197 F1S2X6 F1S365 F1S8W1 F1SIX5 F1SK95 F1SS45 I3LT93 Q8MIB3	ABCG2 ABCG2A ALAD ALAS1 ALAS2 ALB BMDP COX10 COX15 CPOX FECH FLVCR1 HMBS PPOX UROD UROS	Sus scrofa (pig)
VEGFR2 mediated vascular permeability	3-phosphoinositide-dependent protein kinase 1 Cadherin-5 Calmodulin 3 Catenin alpha 1 Catenin beta-1 Catenin delta 1 Caveolin Heat shock protein HSP 90-alpha Heat shock protein HSP 90-alpha Junction plakoglobin Junction plakoglobin Nitric oxide synthase Proto-oncogene vav Ras-related C3 botulinum toxin substrate 1 Vav guanine nucleotide exchange factor 2 non-specific serine/threonine protein kinase non-specific serine/threonine protein kinase	A0A286ZJQ9 A0A286ZQX2 A0A286ZV67 A0A287B8N4 A0A2C9F3E9 A0A5G2QJC4 A0A5G2QWK6 A0A5K1VSS6 A0A8I8C3K7 A0A8W4FI56 F1RGJ2 F1SQW0 F6QAP1 O02705 Q7YSG7 Q8WNW3 Q8WNW5	CALM3 CAV1 CDH5 CTNNA1 CTNNB1 CTNND1 HSP90A HSP90AA1 HSPCA JUP Jup NOS3 PAK1 PAK2 PDPK1 RAC1 VAV1 VAV2	Sus scrofa (pig)
FRS-mediated FGFR4 signaling	Fibroblast growth factor 23 Fibroblast growth factor 9 Fibroblast growth factor receptor substrate 3 Fibroblast growth factor receptor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor GTPase HRas GTPase NRas Growth factor receptor bound protein 2 Klotho beta Multifunctional fusion protein SOS Ras/Rac guanine nucleotide exchange factor 1 Tyrosine-protein phosphatase non-receptor type small monomeric GTPase	A0A286ZUQ0 A0A287AFX3 A0A287AXR0 A0A287B3V5 A0A287BGK8 A0A480LMF4 A0A5G2QLX0 A0A5G2QUY7 A0A5G2R7G2 B6E241 F1RM38 F1RUW8 F1RY80 F1S3B8 F1SET9 I3L560 I3LCQ9 I3LR27 Q2MJK3 Q95L12	FGF1 FGF16 FGF18 FGF19 FGF2 FGF20 FGF23 FGF4 FGF6 FGF8 FGF9 FGFR4 FRS3 Fgf4 GRB2 HRAS KLB KRAS NRAS PTPN11 SOS1	Sus scrofa (pig)
Passive transport by Aquaporins	Aquaporin 7 Aquaporin 9 Aquaporin-10 Aquaporin-1 Aquaporin-2 Aquaporin-3 Aquaporin-4 Aquaporin-5 Aquaporin-8 Aquaporin	A0A286ZI15 A0A287AT23 A0A287AVV4 A0A287BD05 A8W649 A8WCF7 A9Y007 B2D2K0 F1DQZ7 I3LH92	AQP1 AQP10 AQP12 AQP2 AQP3 AQP4 AQP5 AQP7 AQP8 AQP9	Sus scrofa (pig)
Nuclear Receptor transcription pathway	Androgen receptor Bile acid receptor isoform 4 Estrogen receptor beta Estrogen receptor Estrogen related receptor alpha Estrogen related receptor beta Estrogen related receptor gamma Glucocorticoid receptor Hepatocyte nuclear factor 4 alpha Hepatocyte nuclear factor 4 gamma Mediator of RNA polymerase II transcription subunit 1 Mineralocorticoid receptor Neuron-derived orphan receptor-1 alfa Nuclear receptor corepressor 1 Nuclear receptor corepressor 2 Nuclear receptor subfamily 0 group B member 1 Nuclear receptor subfamily 0 group B member 2 Nuclear receptor subfamily 1 group D member 1 Nuclear receptor subfamily 1 group D member 2 Nuclear receptor subfamily 1 group H member 2 Nuclear receptor subfamily 1 group H member 3 Nuclear receptor subfamily 1 group I member 2 Nuclear receptor subfamily 1 group I member 3 Nuclear receptor subfamily 2 group C member 1 Nuclear receptor subfamily 2 group E member 1 Nuclear receptor subfamily 2 group E member 3 Nuclear receptor subfamily 2 group F member 1 Nuclear receptor subfamily 2 group F member 6 Nuclear receptor subfamily 4 group A member 1 Nuclear receptor subfamily 4 group A member 2 Nuclear receptor subfamily 5 group A member 2 Nuclear receptor subfamily 6 group A member 1 Peroxisome proliferator activated receptor delta Peroxisome proliferator-activated receptor alpha Peroxisome proliferator-activated receptor gamma Progesterone receptor RAR related orphan receptor A RAR related orphan receptor B Retinoic acid receptor RXR-gamma Retinoic acid receptor RXR Retinoic acid receptor alpha Retinoid X receptor beta Steroidogenic factor 1 Thyroid hormone receptor alpha Thyroid hormone receptor beta Vitamin D3 receptor	A0A286ZW94 A0A287A1X6 A0A287A395 A0A287A9D2 A0A287AWT1 A0A287B3I8 A0A287B660 A0A287B6Y7 A0A287BBC6 A0A287BCG5 A0A287BP95 A0A288CG33 A0A288CG37 A0A480PNE7 A0A5G2R5L5 A0A5G2R9M5 A0A8W4F8E8 A0A8W4F919 A0A8W4FPC3 A0A8X9AEJ2 A3RGC1 F1RFN3 F1RH38 F1RNX7 F1RQP2 F1RTM6 F1RWL2 F1S2P9 F1S962 F1SIS0 F1SM76 F1SPV3 F1SQP7 F1SRR6 F1STR7 F1SV76 F6PWE0 F6Q6I2 I3LL46 I3LU21 O62807 O97716 O97726 P79387 Q0GFF6 Q29040	AR ESR ESR1 ESR2 ESRRA ESRRB ESRRG FTZF1 HNF4A HNF4G MED1 NCOR1 NCOR2 NOR-1 NR0B1 NR0B2 NR1A1 NR1C3 NR1D1 NR1D2 NR1H2 NR1H3 NR1H4 NR1I1 NR1I2 NR1I3 NR2B3 NR2C1 NR2E1 NR2E3 NR2F1 NR2F6 NR3A1 NR3C1 NR3C2 NR4A1 NR4A2 NR4A3 NR5A1 NR5A2 NR6A1 PGR PPARA PPARD PPARG RARA RORA RORB RXRA RXRB RXRG THRA THRB VDR	Sus scrofa (pig)
Melanin biosynthesis	5,6-dihydroxyindole-2-carboxylic acid oxidase L-dopachrome tautomerase OCA2 melanosomal transmembrane protein Solute carrier family 45 member 2 Tyrosinase	A0A8W4FBC9 F1SP14 F6Q7U8 Q4R1H1 Q4R1H3	DCT OCA2 SLC45A2 TYR TYRP1 TYRP2	Sus scrofa (pig)
Interleukin-3, Interleukin-5 and GM-CSF signaling	14-3-3 protein zeta/delta Colony stimulating factor 2 receptor subunit beta Fibronectin type-III domain-containing protein Granulocyte-macrophage colony-stimulating factor Interleukin 5 receptor subunit alpha Interleukin-5 Phosphatidylinositol 3-kinase regulatory subunit alpha isoform 2 Phosphatidylinositol 3-kinase regulatory subunit beta Proto-oncogene vav SHC-transforming protein 1 Signal transducer and activator of transcription Signal transducer and activator of transcription Tyrosine-protein kinase JAK2 Tyrosine-protein kinase Tyrosine-protein phosphatase non-receptor type phosphatidylinositol-4,5-bisphosphate 3-kinase phosphatidylinositol-4,5-bisphosphate 3-kinase phosphatidylinositol-4,5-bisphosphate 3-kinase	A0A0A0MY60 A0A286ZQX2 A0A287BFJ1 A0A480LMF4 A0A5G2QEJ3 A0A5K1UB41 A0A5K1UPW2 A0A5K1V5Y3 A0A8X9AEI7 E7CR01 F1S916 F1SEA4 F1SFL9 F1SKR9 F2Z558 O19064 Q29118 Q9MYM5	CSF2 CSF2RA CSF2RB IL5 IL5RA JAK2 PIK3CA PIK3CB PIK3CD PIK3R1 PIK3R2 PTPN11 SHC1 STAT5A STAT5B TEC VAV1 YWHAZ stat5B	Sus scrofa (pig)
TNFR1-induced proapoptotic signaling	Baculoviral IAP repeat containing 2 FAS-associated death domain protein Inhibitor of nuclear factor kappa B kinase subunit epsilon Putative inhibitor of apoptosis RBR-type E3 ubiquitin transferase RING-type E3 ubiquitin transferase RanBP-type and C3HC4-type zinc finger-containing protein 1 Receptor interacting serine/threonine kinase 1 Spermatogenesis-associated protein 2 TANK binding kinase 1 TNF receptor-associated factor Tumor necrosis factor receptor superfamily member 1A Tumor necrosis factor receptor type 1-associated DEATH domain protein Tumor necrosis factor Ubiquitin carboxyl-terminal hydrolase 4 Ubiquitin carboxyl-terminal hydrolase CYLD Ubiquitin carboxyl-terminal hydrolase Ubiquitin carboxyl-terminal hydrolase ubiquitinyl hydrolase 1 ubiquitinyl hydrolase 1 ubiquitinyl hydrolase 1	A0A286ZI91 A0A286ZVH7 A0A286ZYB8 A0A287AL42 A0A287AQJ4 A0A287AUG2 A0A287B5E3 A0A287BGB4 A0A287BPE4 A0A287BRT1 F1RVZ4 F1S196 F1S6A4 F1S7J3 F1SDG3 I3LH37 I3LI16 M9MMN5 O62640 P23563 Q56VC2	BIRC2 CYLD FADD IKBKE MIB2 OTUD1 OTUD7B PIAP RBCK1 RIPK1 RNF31 SPATA2 TBK1 TNF TNFA TNFAIP3 TNFRSF1A TNFRSF6 TNFSF2 TRADD TRAF2 USP2 USP21 USP4	Sus scrofa (pig)
Interleukin-12 signaling	Interleukin 12 receptor subunit beta 1 Interleukin 12 receptor subunit beta 2 Interleukin-12 subunit alpha Interleukin-12 subunit beta Protein disulfide-isomerase Signal transducer and activator of transcription Tyrosine-protein kinase JAK2 Tyrosine-protein kinase Tyrosine-protein kinase	A0A286ZLI2 A0A5G2QAF8 A0A5G2RDD7 A0A5S6GA10 E1U8C4 F1S3L9 F1S826 O19064 Q28938	IL12A IL12B IL12RB1 IL12RB2 JAK1 JAK2 LOC100736717 P4HB STAT4 TYK2 stat4	Sus scrofa (pig)
PI-3K cascade:FGFR1	Fibroblast growth factor 23 Fibroblast growth factor 9 Fibroblast growth factor receptor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor GRB2 associated binding protein 1 Growth factor receptor bound protein 2 Klotho Multifunctional fusion protein Phosphatidylinositol 3-kinase regulatory subunit alpha isoform 2 Tyrosine-protein phosphatase non-receptor type phosphatidylinositol-4,5-bisphosphate 3-kinase	A0A287AAE4 A0A287AFX3 A0A287AXR0 A0A287BG34 A0A287BGK8 A0A480LMF4 A0A5G2R7G2 A0A5K1UB41 B6E241 F1RM38 F1RSR6 F1RY78 F1RY80 F1SET9 F1SKR9 F1SMG2 K7GMT0 K7GQJ1 Q95L12	FGF1 FGF10 FGF2 FGF20 FGF22 FGF23 FGF3 FGF4 FGF5 FGF6 FGF8 FGF9 FGFR1 Fgf4 GAB1 GRB2 KL PIK3CA PIK3R1 PTPN11	Sus scrofa (pig)
Regulation of IFNG signaling	E3 SUMO-protein ligase PIAS1 isoform 2 Interferon gamma receptor 1 Interferon gamma receptor 2 Interferon gamma Signal transducer and activator of transcription Small ubiquitin-related modifier 1 Suppressor of cytokine signaling 1 Suppressor of cytokine signaling 3 Tyrosine-protein kinase JAK2 Tyrosine-protein kinase Tyrosine-protein phosphatase non-receptor type	A0A286ZLI2 A0A286ZN85 A0A287B963 A0A287BNZ9 A7WLH8 E5EZY0 E7CR04 F1S692 I3LJA1 O19064 P17803	IFNG IFNGR1 IFNGR2 JAK1 JAK2 PIAS1 PTPN2 SOCS1 SOCS3 STAT1 SUMO1 socs1	Sus scrofa (pig)
ESR-mediated signaling	Estrogen receptor beta Estrogen receptor Heat shock protein HSP 90-alpha Heat shock protein HSP 90-alpha Heat shock protein HSP 90-beta Prostaglandin E synthase 3 Serine/threonine-protein phosphatase peptidylprolyl isomerase peptidylprolyl isomerase	A0A286ZKC5 A0A5G2QVN7 A0A8I8C3K7 A0A8W4FCG7 F1RM25 F1SL99 F1SRR6 O02705 Q29040	ESR ESR1 ESR2 FKBP4 FKBP5 HSP90A HSP90AA1 HSP90AB1 HSPCA NR3A1 PPP5C PTGES3	Sus scrofa (pig)

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