GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	March 20, 2024
ECODAB	April 1, 2019

Displaying entries **176 - 200** of **360** in total

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Pathway Name	Protein Name	UniProt ID	Gene Symbol ▲	Organism	GlyTouCan ID
TNF receptor superfamily (TNFSF) members mediating non-canonical NF-kB pathway	B-cell activating factor Baculoviral IAP repeat containing 2 CD40 ligand Lymphotoxin beta receptor Lymphotoxin-alpha Lymphotoxin-beta Mitogen-activated protein kinase kinase kinase 14 Putative inhibitor of apoptosis TNF receptor superfamily member 11a TNF receptor superfamily member 12A TNF receptor superfamily member 13C TNF receptor-associated factor TNF receptor-associated factor TNF superfamily member 11 TNF superfamily member 12 Tumor necrosis factor receptor superfamily member 5	A0A287AJ47 A0A287AWB6 A0A5G2Q934 A0A8W4FAU5 A0A8W4FCV1 A0MTC9 F1RJX1 F1RR25 F1RVZ4 I3L7R8 I3L871 I3LH37 K7GN73 O62640 P26445 Q8SQ34	BIRC2 CD40 CD40LG LTA LTB LTBR MAP3K14 PIAP TNFB TNFRSF11A TNFRSF12A TNFRSF13C TNFRSF5 TNFSF1 TNFSF11 TNFSF12 TNFSF13B TRAF2 TRAF3	Sus scrofa (pig)
TNFR1-induced NF-kappa-B signaling pathway	Baculoviral IAP repeat containing 2 IkappaB kinase Inhibitor of nuclear factor kappa-B kinase subunit alpha Mitogen-activated protein kinase kinase kinase 7 NF-kappa-B essential modulator Optineurin Putative inhibitor of apoptosis RBR-type E3 ubiquitin transferase RanBP-type and C3HC4-type zinc finger-containing protein 1 Receptor interacting serine/threonine kinase 1 Small ribosomal subunit protein RACK1 Spermatogenesis-associated protein 2 TGF-beta activated kinase 1 (MAP3K7) binding protein 1 TGF-beta activated kinase 1 (MAP3K7) binding protein 2 TGF-beta activated kinase 1 (MAP3K7) binding protein 3 TNF receptor-associated factor TNF receptor-associated factor Tumor necrosis factor receptor superfamily member 1A Tumor necrosis factor receptor type 1-associated DEATH domain protein Tumor necrosis factor Ubiquitin carboxyl-terminal hydrolase 4 Ubiquitin carboxyl-terminal hydrolase CYLD Ubiquitin carboxyl-terminal hydrolase Ubiquitin carboxyl-terminal hydrolase ubiquitinyl hydrolase 1 ubiquitinyl hydrolase 1 ubiquitinyl hydrolase 1	A0A286ZI91 A0A286ZVH7 A0A286ZYB8 A0A287A5Q1 A0A287AQJ4 A0A287AUG2 A0A287BGB4 A0A287BPE4 A0A287BRT1 A0A481CGW8 A9QT41 B0LXP5 F1RVZ4 F1S196 F1S6A4 F1S7J3 F1S7S1 F1S8V5 F1SDG3 F1SME2 I3LH37 I3LI16 K7GLB8 O62640 P23563 P63246 Q7YS99	BIRC2 CHUK CYLD GNB2L1 IKBKB IKBKG MAP3K7 OPTN OTUD1 OTUD7B PIAP RACK1 RBCK1 RIPK1 RNF31 SPATA2 TAB1 TAB2 TAB3 TAK1b TNF TNFA TNFAIP3 TNFRSF1A TNFSF2 TRADD TRAF1 TRAF2 USP2 USP21 USP4	Sus scrofa (pig)
TNFR1-induced proapoptotic signaling	Baculoviral IAP repeat containing 2 FAS-associated death domain protein Inhibitor of nuclear factor kappa B kinase subunit epsilon Putative inhibitor of apoptosis RBR-type E3 ubiquitin transferase RING-type E3 ubiquitin transferase RanBP-type and C3HC4-type zinc finger-containing protein 1 Receptor interacting serine/threonine kinase 1 Spermatogenesis-associated protein 2 TANK binding kinase 1 TNF receptor-associated factor Tumor necrosis factor receptor superfamily member 1A Tumor necrosis factor receptor type 1-associated DEATH domain protein Tumor necrosis factor Ubiquitin carboxyl-terminal hydrolase 4 Ubiquitin carboxyl-terminal hydrolase CYLD Ubiquitin carboxyl-terminal hydrolase Ubiquitin carboxyl-terminal hydrolase ubiquitinyl hydrolase 1 ubiquitinyl hydrolase 1 ubiquitinyl hydrolase 1	A0A286ZI91 A0A286ZVH7 A0A286ZYB8 A0A287AL42 A0A287AQJ4 A0A287AUG2 A0A287B5E3 A0A287BGB4 A0A287BPE4 A0A287BRT1 F1RVZ4 F1S196 F1S6A4 F1S7J3 F1SDG3 I3LH37 I3LI16 M9MMN5 O62640 P23563 Q56VC2	BIRC2 CYLD FADD IKBKE MIB2 OTUD1 OTUD7B PIAP RBCK1 RIPK1 RNF31 SPATA2 TBK1 TNF TNFA TNFAIP3 TNFRSF1A TNFRSF6 TNFSF2 TRADD TRAF2 USP2 USP21 USP4	Sus scrofa (pig)
Molecules associated with elastic fibres	Bone morphogenetic protein 10 Bone morphogenetic protein 2 Bone morphogenetic protein 4 Bone morphogenetic protein 7 (Osteogenic protein 1) EGF containing fibulin extracellular matrix protein 2 Fibulin-5 Growth differentiation factor 5 Integrin beta Integrin beta Integrin beta Integrin beta Integrin beta Integrin subunit alpha 8 Integrin subunit alpha V Latent transforming growth factor beta binding protein 1 Latent transforming growth factor beta binding protein 3 Latent transforming growth factor beta binding protein 4 Microfibril associated protein 2 Microfibril associated protein 4 Microfibril associated protein 5 Transforming growth factor beta-1 proprotein Transforming growth factor beta-3 proprotein Transforming growth factor beta-3 proprotein Transforming growth factor beta Vitronectin	A0A286ZV08 A0A286ZWQ1 A0A286ZZE2 A0A287A7C6 A0A287AZ66 A0A287AZP0 A0A287BIH5 A0A287BIU2 A0A5G2QNS3 A0A5G2R2Y0 A0A5G2R7K7 A0A5K1V6L8 A0A8W4FF41 A5GFN2 A7LJT9 A9X6R3 F1RRJ9 F1RW86 F1S4W8 F1SD87 K7GQ83 K7GSJ9 P07200 P15203 P48819	BMP10 BMP2 BMP4 BMP7 EFEMP2 FBLN5 GDF5 ITGA8 ITGAV ITGB1 ITGB3 ITGB5 ITGB6 ITGB8 LTBP1 LTBP3 LTBP4 MFAP2 MFAP4 MFAP5 TGFB1 TGFB2 TGFB3 VTN bmp4	Sus scrofa (pig)
Antimicrobial peptides	Antibacterial peptide BPI fold containing family A member 2 BPI fold containing family B member 1 BPI fold containing family B member 2 BPI fold containing family B member 4 BPI fold-containing family A member 1 Bactericidal permeability-increasing protein C-type lectin domain-containing protein C-type lectin domain-containing protein Chromogranin-A Clusterin Clusterin Elafin Epididymal peptidase inhibitor Fibrinogen C-terminal domain-containing protein Granulysin Lactotransferrin Liver-expressed antimicrobial peptide 2 Lysozyme C-3 N-acetylmuramoyl-L-alanine amidase Non-secretory ribonuclease Peptidase S1 domain-containing protein Peptidoglycan recognition protein 3 Peptidoglycan recognition protein 4 Peptidoglycan-recognition protein Regenerating islet-derived 3 gamma Uncharacterized protein trypsin	A0A286ZI97 A0A287AE25 A0A287AN19 A0A287BDI2 A0A287BGS7 A0A287BLV6 A0A287BME6 A0A287BQB3 A0A5G2QHA2 A0A5G2QU73 A0A5G2R6C7 A0A5G2RCV2 A0A5G2RIT7 A0A5K1UBC7 A0A5S8KLN1 A0A8X9AES5 A7J149 B8YGC1 C6L245 F1SD66 F1SFU8 F1SNX2 K7GS01 K7GSX9 P12069 Q29125 Q29549 Q6YT39	BPI BPIFA1 BPIFA2 BPIFB1 BPIFB2 BPIFB4 CHGA CLU EPPIN GNLY LEAP2 LOC100154047 LOC100520832 LOC100624628 LOC102163838 LOC110255221 LOC110260309 LTF PGLYRP1 PGLYRP2 PGLYRP3 PGLYRP4 PMAP-36 PRSS2 REG3G try	Sus scrofa (pig)	G49108TO
Toll Like Receptor 4 (TLR4) Cascade	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma Bactericidal permeability-increasing protein CD180 antigen Integrin beta Integrin subunit alpha M Lipopolysaccharide-binding protein Lymphocyte antigen 86 Lymphocyte antigen 96 Monocyte differentiation antigen CD14 TIR domain-containing adapter molecule 2 Toll-like receptor 4 dynamin GTPase dynamin GTPase dynamin GTPase	A0A287A869 A0A287AK86 A0A287AN09 A0A287B5Y6 A0A287B8X7 A0A287BLV6 A0A287BMU9 A0A480K9W0 A0A5G2REH3 A2SW51 A7BG67 F1S475 I3LCZ7 Q7YRL4	BPI CD14 CD180 DNM1 DNM2 DNM3 ITGAM ITGB2 LBP LY64 LY86 LY96 PLCG2 TICAM2 TLR4	Sus scrofa (pig)
Interleukin-7 signaling	Bromodomain and WD repeat domain containing 1 Cytokine receptor-like factor 2 Histone H3 Histone H3 Insulin receptor substrate 1 Insulin receptor substrate 2 Interleukin 2 receptor gamma Interleukin-7 receptor subunit alpha Interleukin-7 Phosphatidylinositol 3-kinase regulatory subunit alpha isoform 2 Phosphatidylinositol 3-kinase regulatory subunit beta SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 Signal transducer and activator of transcription 3 Signal transducer and activator of transcription Signal transducer and activator of transcription Signal transducer and activator of transcription Tyrosine-protein kinase Tyrosine-protein kinase	A0A0A0MY60 A0A286ZJQ0 A0A286ZLI2 A0A286ZSF3 A0A287ARN1 A0A287B726 A0A2C9F3G4 E7CR01 F1RVA0 F1S916 F1SKR9 I3LLF1 K7GLC0 K7GSE8 K7GT64 Q19S50 Q76KD0 Q9N2G6	BRWD1 CRLF2 H3C12 H3C14 H3C15 H3C4 H3C6 HIST1H3E IL2RG IL7 IL7R IRS1 IRS2 JAK1 JAK3 LOC110257900 PIK3R1 PIK3R2 SMARCA4 STAT3 STAT5A STAT5B stat5B	Sus scrofa (pig)
Integrin cell surface interactions	Basigin CD44 antigen Cadherin-1 Cartilage oligomeric matrix protein Collagen alpha-1(XVI) chain Collagen alpha-2(IX) chain Collagen type IV alpha 1 chain Collagen type IV alpha 2 chain Collagen type IV alpha 3 chain Collagen type IV alpha 4 chain Collagen type IX alpha 1 chain Collagen type IX alpha 3 chain Collagen type XIII alpha 1 chain Collagen type XVIII alpha 1 chain Fibrinogen alpha chain Fibrinogen beta chain Fibrinogen gamma chain Fibronectin Integrin alpha-4 isoform 1 preproprotein Integrin alpha-5 Integrin alpha-9 Integrin beta Integrin beta Integrin beta Integrin beta Integrin beta Integrin beta Integrin beta Integrin subunit alpha 10 Integrin subunit alpha 11 Integrin subunit alpha 1 Integrin subunit alpha 2 Integrin subunit alpha 2b Integrin subunit alpha 3 Integrin subunit alpha 6 Integrin subunit alpha 8 Integrin subunit alpha D Integrin subunit alpha E Integrin subunit alpha L Integrin subunit alpha M Integrin subunit alpha V Integrin-binding sialoprotein Intercellular adhesion molecule 1 Intercellular adhesion molecule 2 Intercellular adhesion molecule 4 Intercellular adhesion molecule 5 Junctional adhesion molecule 2 Junctional adhesion molecule 3 Junctional adhesion molecule A Leukocyte surface antigen CD47 Lumican Mucosal addressin cell adhesion molecule 1 isoform a Osteopontin Platelet and endothelial cell adhesion molecule 1 Platelet endothelial cell adhesion molecule Tenascin C Tenascin N Thrombospondin 1 VWFA domain-containing protein Vascular cell adhesion molecule 1 Vitronectin	A0A286ZIL9 A0A286ZJF0 A0A286ZTM0 A0A287AAG8 A0A287AD51 A0A287AI56 A0A287AK86 A0A287AQ10 A0A287AZ66 A0A287AZF2 A0A287B874 A0A287BIH5 A0A480VGP1 A0A5G2QD63 A0A5G2QGZ8 A0A5G2QUU1 A0A5G2QVP2 A0A5G2QY29 A0A5G2QYR6 A0A5G2R3T7 A0A5G2R7K7 A0A5G2R836 A0A5G2REH3 A0A5G2RNE8 A0A5K1V6L8 A0A8W4FC88 A0A8W4FCC2 A0A8W4FP23 A9X6R3 F1RLL9 F1RQY8 F1RRC1 F1RSK4 F1RT62 F1RW86 F1RX36 F1RX37 F1S3J9 F1S3K0 F1S3K1 F1S567 F1S708 F1S902 F1SGT4 F1SMF4 F1SNP0 F1SQ09 F1SR53 F1SS24 F1SS26 I3L5Z1 I3LCD8 I3LUI4 K7GQ83 K7GS31 K9IVL5 P14287 P48819 Q2V6R9 Q95242 Q9GKE8	BSG CD44 CD47 CDH1 COL13A1 COL16A1 COL18A1 COL4A1 COL4A2 COL4A3 COL4A4 COL9A1 COL9A2 COL9A3 COMP F11R FGA FGB FGG FN1 IBSP ICAM1 ICAM2 ICAM4 ICAM5 ITGA1 ITGA10 ITGA11 ITGA2 ITGA2B ITGA3 ITGA4 ITGA5 ITGA6 ITGA8 ITGA9 ITGAD ITGAE ITGAL ITGAM ITGAV ITGB1 ITGB2 ITGB3 ITGB5 ITGB6 ITGB7 ITGB8 JAM2 JAM3 LUM MADCAM1 OPN PECAM1 SPP1 THBS1 TNC TNN VCAM1 VTN	Sus scrofa (pig)
Downregulation of ERBB2 signaling	Betacellulin Cullin-5 E3 ubiquitin-protein ligase CHIP Epiregulin Heat shock protein HSP 90-alpha Heat shock protein HSP 90-alpha Hsp90 co-chaperone Cdc37 Neuregulin 2 Neuregulin 3 Polyubiquitin-C Pro-epidermal growth factor Pro-neuregulin-1, membrane-bound isoform Proheparin-binding EGF-like growth factor Receptor protein-tyrosine kinase Receptor protein-tyrosine kinase Receptor protein-tyrosine kinase Receptor protein-tyrosine kinase Tyrosine-protein kinase Ubiquitin B Ubiquitin C Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein protein-tyrosine-phosphatase protein-tyrosine-phosphatase	A0A286ZJM1 A0A287A231 A0A287A6I2 A0A287AZA7 A0A287AZM9 A0A287B8P3 A0A287BCW9 A0A287BGG6 A0A287BKD5 A0A2C9F3G2 A0A480J4F4 A0A5G2QBP1 A0A5G2R1H6 A0A5G2R2M6 A0A8I8C3K7 A7U5U2 F1RWM5 F1RXX2 F1S911 F1SSQ9 O02705 P0CG68 Q01580 Q684M6	BTC CDC37 CUL5 DTR EGF EGFR ERBB2 ERBB3 ERBB4 EREG HBEGF HEGFL HSP90A HSP90AA1 HSPCA MATK NRG1 NRG2 NRG3 PTPN12 PTPN18 RPS27A STUB1 UBA52 UBB UBC	Sus scrofa (pig)
Signaling by ERBB2	Betacellulin Epiregulin Heat shock protein HSP 90-alpha Heat shock protein HSP 90-alpha Hsp90 co-chaperone Cdc37 Neuregulin 2 Neuregulin 3 Pro-epidermal growth factor Pro-neuregulin-1, membrane-bound isoform Proheparin-binding EGF-like growth factor Receptor protein-tyrosine kinase Receptor protein-tyrosine kinase Receptor protein-tyrosine kinase Receptor protein-tyrosine kinase Tyrosine-protein kinase Fyn Tyrosine-protein kinase Tyrosine-protein kinase	A0A286ZJM1 A0A287A231 A0A287A6I2 A0A287AZM9 A0A287BCW9 A0A480J4F4 A0A5G2QBP1 A0A5G2QU81 A0A5G2R1H6 A0A8I8C3K7 A1Y2K1 F1RWM5 F1SSQ9 K7GPR7 O02705 Q01580 Q684M6	BTC CDC37 DTR EGF EGFR ERBB2 ERBB3 ERBB4 EREG FYN HBEGF HEGFL HSP90A HSP90AA1 HSPCA NRG1 NRG2 NRG3 SRC YES1	Sus scrofa (pig)
ERBB2 Regulates Cell Motility	Betacellulin Diaphanous related formin 1 Epiregulin Neuregulin 2 Neuregulin 3 Pro-epidermal growth factor Pro-neuregulin-1, membrane-bound isoform Proheparin-binding EGF-like growth factor Protein MEMO1 Receptor protein-tyrosine kinase Receptor protein-tyrosine kinase Receptor protein-tyrosine kinase Receptor protein-tyrosine kinase Transforming protein RhoA	A0A286ZJM1 A0A287A231 A0A287A6I2 A0A287AZM9 A0A287BCW9 A0A480J4F4 A0A5G2QBP1 A0A5G2QRI9 A0A5G2R1H6 F1RWM5 F1SSQ9 F2Z5F8 I3LVS7 Q01580	BTC DIAPH1 DTR EGF EGFR ERBB2 ERBB3 ERBB4 EREG HBEGF HEGFL MEMO1 NRG1 NRG2 NRG3 RHOA	Sus scrofa (pig)
PI3K events in ERBB2 signaling	Betacellulin Epiregulin GRB2 associated binding protein 1 Growth factor receptor bound protein 2 Neuregulin 2 Neuregulin 3 Phosphatidylinositol 3-kinase regulatory subunit alpha isoform 2 Pro-epidermal growth factor Pro-neuregulin-1, membrane-bound isoform Proheparin-binding EGF-like growth factor Receptor protein-tyrosine kinase Receptor protein-tyrosine kinase Receptor protein-tyrosine kinase Receptor protein-tyrosine kinase phosphatidylinositol-4,5-bisphosphate 3-kinase	A0A286ZJM1 A0A287A231 A0A287A6I2 A0A287AZM9 A0A287BCW9 A0A480J4F4 A0A5G2QBP1 A0A5G2R1H6 A0A5K1UB41 B6E241 F1RWM5 F1SKR9 F1SSQ9 K7GMT0 Q01580	BTC DTR EGF EGFR ERBB2 ERBB3 ERBB4 EREG GAB1 GRB2 HBEGF HEGFL NRG1 NRG2 NRG3 PIK3CA PIK3R1	Sus scrofa (pig)
SHC1 events in ERBB2 signaling	Betacellulin Epiregulin Neuregulin 2 Neuregulin 3 Pro-epidermal growth factor Pro-neuregulin-1, membrane-bound isoform Proheparin-binding EGF-like growth factor Protein kinase C epsilon type Protein kinase C Receptor protein-tyrosine kinase Receptor protein-tyrosine kinase Receptor protein-tyrosine kinase Receptor protein-tyrosine kinase SHC-transforming protein 1 protein kinase C protein-tyrosine-phosphatase	A0A286ZJM1 A0A287A231 A0A287A6I2 A0A287AZM9 A0A287BBY6 A0A287BCW9 A0A287BKD5 A0A480J4F4 A0A5G2QBP1 A0A5G2R1H6 A0A5K1V5Y3 F1RV14 F1RWM5 F1S5K7 F1SSQ9 Q01580	BTC DTR EGF EGFR ERBB2 ERBB3 ERBB4 EREG HBEGF HEGFL NRG1 NRG2 NRG3 PRKCA PRKCD PRKCE PTPN12 SHC1	Sus scrofa (pig)
ERBB2 Activates PTK6 Signaling	Betacellulin Epiregulin Neuregulin 2 Neuregulin 3 Pro-epidermal growth factor Pro-neuregulin-1, membrane-bound isoform Proheparin-binding EGF-like growth factor Receptor protein-tyrosine kinase Receptor protein-tyrosine kinase Receptor protein-tyrosine kinase Receptor protein-tyrosine kinase Tyrosine-protein kinase	A0A286ZJM1 A0A286ZYS4 A0A287A231 A0A287A6I2 A0A287AZM9 A0A287BCW9 A0A480J4F4 A0A5G2QBP1 A0A5G2R1H6 F1RWM5 F1SSQ9 Q01580	BTC DTR EGF EGFR ERBB2 ERBB3 ERBB4 EREG HBEGF HEGFL NRG1 NRG2 NRG3 PTK6	Sus scrofa (pig)
Signaling by ERBB4	Betacellulin Epiregulin Neuregulin 2 Neuregulin 3 Pro-epidermal growth factor Pro-neuregulin-1, membrane-bound isoform Proheparin-binding EGF-like growth factor Receptor protein-tyrosine kinase Receptor protein-tyrosine kinase Receptor protein-tyrosine kinase	A0A286ZJM1 A0A287A231 A0A287A6I2 A0A287AZM9 A0A287BCW9 A0A480J4F4 A0A5G2QBP1 A0A5G2R1H6 F1SSQ9 Q01580	BTC DTR EGF EGFR ERBB3 ERBB4 EREG HBEGF HEGFL NRG1 NRG2 NRG3	Sus scrofa (pig)
GRB2 events in ERBB2 signaling	Betacellulin Epiregulin GTPase HRas GTPase NRas Growth factor receptor bound protein 2 Neuregulin 2 Neuregulin 3 Pro-neuregulin-1, membrane-bound isoform Proheparin-binding EGF-like growth factor Receptor protein-tyrosine kinase Receptor protein-tyrosine kinase SOS Ras/Rac guanine nucleotide exchange factor 1 small monomeric GTPase	A0A286ZJM1 A0A286ZUQ0 A0A287A6I2 A0A287AZM9 A0A287BCW9 A0A5G2QLX0 A0A5G2R1H6 B6E241 F1RWM5 F1SSQ9 I3LCQ9 Q01580 Q2MJK3	BTC DTR ERBB2 ERBB4 EREG GRB2 HBEGF HEGFL HRAS KRAS NRAS NRG1 NRG2 NRG3 SOS1	Sus scrofa (pig)
SHC1 events in ERBB4 signaling	Betacellulin Epiregulin GTPase HRas GTPase NRas Growth factor receptor bound protein 2 Neuregulin 2 Neuregulin 3 Pro-neuregulin-1, membrane-bound isoform Proheparin-binding EGF-like growth factor Receptor protein-tyrosine kinase SHC-transforming protein 1 SOS Ras/Rac guanine nucleotide exchange factor 1 small monomeric GTPase	A0A286ZJM1 A0A286ZUQ0 A0A287A6I2 A0A287AZM9 A0A287BCW9 A0A5G2QLX0 A0A5G2R1H6 A0A5K1V5Y3 B6E241 F1SSQ9 I3LCQ9 Q01580 Q2MJK3	BTC DTR ERBB4 EREG GRB2 HBEGF HEGFL HRAS KRAS NRAS NRG1 NRG2 NRG3 SHC1 SOS1	Sus scrofa (pig)
PI3K events in ERBB4 signaling	Betacellulin Epiregulin Neuregulin 2 Neuregulin 3 Phosphatidylinositol 3-kinase regulatory subunit alpha isoform 2 Pro-neuregulin-1, membrane-bound isoform Proheparin-binding EGF-like growth factor Receptor protein-tyrosine kinase phosphatidylinositol-4,5-bisphosphate 3-kinase	A0A286ZJM1 A0A287A6I2 A0A287AZM9 A0A287BCW9 A0A5G2R1H6 A0A5K1UB41 F1SKR9 F1SSQ9 Q01580	BTC DTR ERBB4 EREG HBEGF HEGFL NRG1 NRG2 NRG3 PIK3CA PIK3R1	Sus scrofa (pig)
Regulation of Complement cascade	C5a anaphylatoxin chemotactic receptor 1 CD55 molecule (Cromer blood group) CD59 glycoprotein CD81 molecule Carboxypeptidase B2 Carboxypeptidase N catalytic chain Carboxypeptidase N subunit 2 Clusterin Clusterin Complement C1q B chain Complement C1q C chain Complement C1q subcomponent subunit A Complement C1s Complement C2 Complement C3 Complement C4A (Rodgers blood group) Complement C5 Complement C5a receptor 2 Complement C7 Complement C8 alpha chain Complement C8 gamma chain Complement component C6 Complement component C8 beta chain Complement component C9 Complement factor B Complement factor H Complement factor I Ig lambda chain C region Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Immunoglobulin V-set domain-containing protein Immunoglobulin V-set domain-containing protein Plasma protease C1 inhibitor Prothrombin Sushi domain-containing protein Sushi domain-containing protein Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein Vitronectin complement subcomponent C1r	A0A075B7I6 A0A0A0MY58 A0A286ZIM1 A0A286ZJL9 A0A286ZKR7 A0A286ZLN6 A0A286ZMU4 A0A286ZP42 A0A286ZQH2 A0A286ZSJ7 A0A286ZSX6 A0A286ZTI5 A0A286ZU07 A0A286ZUL8 A0A287A3T6 A0A287A7S8 A0A287AA42 A0A287ADE7 A0A287AE51 A0A287AFQ4 A0A287AIM8 A0A287AKW2 A0A287ALJ6 A0A287AM45 A0A287AM58 A0A287ANU5 A0A287AP28 A0A287APG4 A0A287AQ20 A0A287AT36 A0A287AU93 A0A287AUR4 A0A287AWH3 A0A287AWQ8 A0A287AYC4 A0A287B1Y4 A0A287B5G0 A0A287B6Q2 A0A287BAB3 A0A287BD18 A0A287BDV3 A0A287BH28 A0A287BHK5 A0A287BLF6 A0A287BLH9 A0A287BMT4 A0A287BNF7 A0A287BNX9 A0A287BRE1 A0A480RJC3 A0A5G2NLY0 A0A5G2Q7F8 A0A5G2Q7Q6 A0A5G2QCL1 A0A5G2QHE8 A0A5G2QNN2 A0A5G2QXT5 A0A5G2R8T9 A0A5G2R9V1 A0A5S8KLN1 A0A8W4F6L3 A0A8W4F7N5 A0A8W4F807 A0A8W4F8A6 A0A8W4F8U6 A0A8W4F9I3 A0A8W4FA34 A0A8W4FAN5 A0A8W4FC14 A0A8W4FC15 A0A8W4FC67 A0A8W4FDG3 A0A8W4FDT9 A0A8W4FEK6 A0A8W4FEL9 A0A8W4FGI9 A0A8W4FGK7 A0A8W4FHQ3 A0A8W4FHY5 A0A8W4FI53 A0A8W4FJA1 A0A8W4FJL3 A0A8W4FL59 A0A8W4FLJ3 A0A8W4FMG3 A0A8W4FMI6 A0A8W4FN37 A0A8W4FNE8 A0A8W4FQ38 A0A8W4FQC5 A0A8W4FRI5 F1RK01 F1RL06 F1RQW7 F1S788 F1S8V7 F1S9H7 F1SIB1 F1SJW8 F1SMJ1 F1STC2 F1STC3 F1STC5 I3L6U3 I3LBK0 I3LF89 I3LUE7 K7GLM8 K7GPT9 O62680 P01846 P48819 Q29549	C1QA C1QB C1QC C1R C1S C2 C3 C4A C5 C5AR1 C5AR2 C6 C7 C8A C8B C8G C9 CD55 CD59 CD81 CFB CFH CFI CLU CPB2 CPN1 CPN2 F2 IGKV5-2 LOC100125542 LOC100523213 SERPING1 VTN	Sus scrofa (pig)
Initial triggering of complement	Collectin subfamily member 10 Collectin-11 Complement C1q B chain Complement C1q C chain Complement C1q subcomponent subunit A Complement C1s Complement C2 Complement C4A (Rodgers blood group) Ficolin (collagen/fibrinogen domain containing lectin) 2 (hucolin) Ficolin (collagen/fibrinogen domain containing) 1 Ig lambda chain C region Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Immunoglobulin V-set domain-containing protein Immunoglobulin V-set domain-containing protein MBL associated serine protease 1 MBL associated serine protease 2 Mannose-binding protein C Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein complement subcomponent C1r	A0A075B7I6 A0A0A0MY58 A0A286ZIM1 A0A286ZJL9 A0A286ZKR7 A0A286ZLN6 A0A286ZMU4 A0A286ZP42 A0A286ZQH2 A0A286ZSJ7 A0A286ZSX6 A0A286ZU07 A0A286ZUL8 A0A287A3T6 A0A287A7S8 A0A287AA42 A0A287ADE7 A0A287AE51 A0A287AKW2 A0A287ALJ6 A0A287AM45 A0A287AM58 A0A287ANU5 A0A287AP28 A0A287APG4 A0A287ATF0 A0A287AU93 A0A287AUR4 A0A287AWH3 A0A287AWQ8 A0A287AYC4 A0A287B1Y4 A0A287B5G0 A0A287BAB3 A0A287BDV3 A0A287BH28 A0A287BHK5 A0A287BLH9 A0A287BMT4 A0A287BNF7 A0A287BNX9 A0A287BRE1 A0A480RJC3 A0A5G2NLY0 A0A5G2Q7F8 A0A5G2Q7Q6 A0A5G2QCL1 A0A5G2QE59 A0A5G2QFX9 A0A5G2QNN2 A0A5G2QP75 A0A5G2QXT5 A0A5G2R9V1 A0A8W4F6L3 A0A8W4F7N5 A0A8W4F807 A0A8W4F8U6 A0A8W4F9I3 A0A8W4FA34 A0A8W4FAN5 A0A8W4FC14 A0A8W4FC15 A0A8W4FC67 A0A8W4FDG3 A0A8W4FEK6 A0A8W4FEL9 A0A8W4FGI9 A0A8W4FGK7 A0A8W4FHQ3 A0A8W4FHY5 A0A8W4FI53 A0A8W4FJA1 A0A8W4FJL3 A0A8W4FL59 A0A8W4FLJ3 A0A8W4FMG3 A0A8W4FMI6 A0A8W4FN37 A0A8W4FNE8 A0A8W4FNY0 A0A8W4FQ38 A0A8W4FQC5 A0A8W4FRI5 F1RL06 F1RQW7 F1S9H7 F1STC2 F1STC3 F1STC5 I3L6U3 I3LBK0 I3LEW0 K7GKU8 P01846	C1QA C1QB C1QC C1R C1S C2 C4A COLEC10 COLEC11 FCN1 FCN2 IGKV5-2 LOC100125542 LOC100523213 MASP1 MASP2 MBL2	Sus scrofa (pig)	G49108TO G57321FI
Terminal pathway of complement	Clusterin Clusterin Complement C5 Complement C7 Complement C8 alpha chain Complement C8 gamma chain Complement component C6 Complement component C8 beta chain Complement component C9	A0A287AFQ4 A0A287AIM8 A0A287AT36 A0A5G2R8T9 A0A5S8KLN1 A0A8W4F8A6 F1S788 F1SMJ1 Q29549	C5 C6 C7 C8A C8B C8G C9 CLU	Sus scrofa (pig)
Inactivation, recovery and regulation of the phototransduction cascade	Calmodulin 3 Calmodulin-lysine N-methyltransferase Cyclic nucleotide gated channel subunit beta 1 G protein-coupled receptor kinase G protein-coupled receptor kinase Glycylpeptide N-tetradecanoyltransferase Glycylpeptide N-tetradecanoyltransferase Guanine nucleotide-binding protein subunit beta-5 Guanylate cyclase Guanylyl cyclase-activating protein 2 Methionine aminopeptidase 2 Methionine aminopeptidase Phosphodiesterase Recoverin Regulator of G-protein signaling 9-binding protein Regulator of G-protein signaling 9 Rhodopsin kinase GRK7 Rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma Rhodopsin Serine/threonine-protein phosphatase with EF-hands cGMP-gated cation channel alpha-1	A0A287AGE9 A0A287AL00 A0A287BB66 A0A480L5Q2 A0A5G2QFC3 A0A5G2QWK6 A0A5G2R841 A0A8W4FII8 F1RF40 F1RL89 F1RN35 F1RR06 F1RUU3 F1S5K4 F1S8P7 I3LJL1 I3LR47 I3LSP1 I3LTH3 O18766 Q8WP15	CALM3 CAMKMT CNGA1 CNGB1 GNB5 GRK1 GRK4 GRK7 GUCA1B GUCY2D METAP1 METAP2 NMT1 NMT2 PDE6A PDE6G PPEF1 RCVRN RGS9 RGS9BP RHO RHO1	Sus scrofa (pig)
Extra-nuclear estrogen signaling	Calmodulin 3 Caveolin-2 Caveolin Estrogen receptor beta Estrogen receptor G protein subunit beta 2 G protein subunit beta 3 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 Guanine nucleotide-binding protein G(i) subunit alpha-1 Guanine nucleotide-binding protein G(i) subunit alpha-2 Guanine nucleotide-binding protein G(i) subunit alpha-3 Guanine nucleotide-binding protein subunit beta-5 Guanine nucleotide-binding protein subunit gamma Guanine nucleotide-binding protein subunit gamma Guanine nucleotide-binding protein subunit gamma Guanine nucleotide-binding protein subunit gamma Guanine nucleotide-binding protein subunit gamma Guanine nucleotide-binding protein subunit gamma Guanine nucleotide-binding protein subunit gamma Guanine nucleotide-binding protein subunit gamma Guanine nucleotide-binding protein subunit gamma Guanine nucleotide-binding protein subunit gamma Heat shock protein HSP 90-alpha Heat shock protein HSP 90-alpha Matrix metallopeptidase 7 Matrix metalloproteinase-9 Nitric oxide synthase Phosphatidylinositol 3-kinase regulatory subunit alpha isoform 2 Phosphatidylinositol 3-kinase regulatory subunit beta Proheparin-binding EGF-like growth factor SHC-transforming protein 1 Sphingosine kinase 1 Sphingosine-1-phosphate receptor 3 Striatin Stromelysin-1 Tyrosine-protein kinase receptor Tyrosine-protein kinase phosphatidylinositol-4,5-bisphosphate 3-kinase type I protein arginine methyltransferase	A0A286ZJQ9 A0A286ZLJ8 A0A286ZVN4 A0A287ADM2 A0A287AHC5 A0A287AW90 A0A287AZD5 A0A287B6W0 A0A287BTE0 A0A480UI36 A0A5G2QFC3 A0A5G2QWK6 A0A5G2QYS1 A0A5G2R753 A0A5K1UB41 A0A5K1V5Y3 A0A8I8C3K7 A0A8W4FGM1 B9TRW9 F1CK17 F1RN19 F1RWP6 F1S4P0 F1S916 F1SKR9 F1SLU8 F1SRR6 F1SV58 F1SV71 F2Z4Z8 I3LM81 K7GPR7 O02705 Q01580 Q06AS6 Q06AS8 Q29040 Q2QLE2 Q7YSG7	CALM3 CAV1 CAV2 DTR ESR ESR1 ESR2 GNAI1 GNAI2 GNAI3 GNB1 GNB2 GNB3 GNB5 GNG10 GNG11 GNG12 GNG3 GNG4 GNG5 GNG7 GNG8 HBEGF HEGFL HSP90A HSP90AA1 HSPCA IGF1R LOC100621431 LOC110255211 MMP3 MMP7 MMP9 NOS3 NR3A1 PIK3CA PIK3R1 PIK3R2 PRMT1 S1PR3 SHC1 SPHK1 SRC STRN	Sus scrofa (pig)
VEGFR2 mediated vascular permeability	3-phosphoinositide-dependent protein kinase 1 Cadherin-5 Calmodulin 3 Catenin alpha 1 Catenin beta-1 Catenin delta 1 Caveolin Heat shock protein HSP 90-alpha Heat shock protein HSP 90-alpha Junction plakoglobin Junction plakoglobin Nitric oxide synthase Proto-oncogene vav Ras-related C3 botulinum toxin substrate 1 Vav guanine nucleotide exchange factor 2 non-specific serine/threonine protein kinase non-specific serine/threonine protein kinase	A0A286ZJQ9 A0A286ZQX2 A0A286ZV67 A0A287B8N4 A0A2C9F3E9 A0A5G2QJC4 A0A5G2QWK6 A0A5K1VSS6 A0A8I8C3K7 A0A8W4FI56 F1RGJ2 F1SQW0 F6QAP1 O02705 Q7YSG7 Q8WNW3 Q8WNW5	CALM3 CAV1 CDH5 CTNNA1 CTNNB1 CTNND1 HSP90A HSP90AA1 HSPCA JUP Jup NOS3 PAK1 PAK2 PDPK1 RAC1 VAV1 VAV2	Sus scrofa (pig)
Glycogen breakdown (glycogenolysis)	Alpha-1,4 glucan phosphorylase Alpha-1,4 glucan phosphorylase Calmodulin 3 Lysosomal alpha-glucosidase Phosphorylase b kinase regulatory subunit Phosphorylase b kinase regulatory subunit Phosphorylase b kinase regulatory subunit glycogenin glucosyltransferase glycogenin glucosyltransferase phosphorylase kinase	A0A286ZUI9 A0A287AGE8 A0A287AL94 A0A287B6P0 A0A287BBS7 A0A5G2QWK6 A0A5G2RE07 F1RG75 F1RPM0 F1RZ82	CALM3 GAA GYG1 GYG2 PHKA1 PHKA2 PHKB PHKG2 PYGL PYGM	Sus scrofa (pig)	G58161NS

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