GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	March 20, 2024
ECODAB	April 1, 2019

Displaying entries **176 - 200** of **360** in total

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Pathway Name	Protein Name	UniProt ID	Gene Symbol ▼	Organism	GlyTouCan ID
Signaling by ERBB2	Betacellulin Epiregulin Heat shock protein HSP 90-alpha Heat shock protein HSP 90-alpha Hsp90 co-chaperone Cdc37 Neuregulin 2 Neuregulin 3 Pro-epidermal growth factor Pro-neuregulin-1, membrane-bound isoform Proheparin-binding EGF-like growth factor Receptor protein-tyrosine kinase Receptor protein-tyrosine kinase Receptor protein-tyrosine kinase Receptor protein-tyrosine kinase Tyrosine-protein kinase Fyn Tyrosine-protein kinase Tyrosine-protein kinase	A0A286ZJM1 A0A287A231 A0A287A6I2 A0A287AZM9 A0A287BCW9 A0A480J4F4 A0A5G2QBP1 A0A5G2QU81 A0A5G2R1H6 A0A8I8C3K7 A1Y2K1 F1RWM5 F1SSQ9 K7GPR7 O02705 Q01580 Q684M6	BTC CDC37 DTR EGF EGFR ERBB2 ERBB3 ERBB4 EREG FYN HBEGF HEGFL HSP90A HSP90AA1 HSPCA NRG1 NRG2 NRG3 SRC YES1	Sus scrofa (pig)
Downregulation of ERBB2 signaling	Betacellulin Cullin-5 E3 ubiquitin-protein ligase CHIP Epiregulin Heat shock protein HSP 90-alpha Heat shock protein HSP 90-alpha Hsp90 co-chaperone Cdc37 Neuregulin 2 Neuregulin 3 Polyubiquitin-C Pro-epidermal growth factor Pro-neuregulin-1, membrane-bound isoform Proheparin-binding EGF-like growth factor Receptor protein-tyrosine kinase Receptor protein-tyrosine kinase Receptor protein-tyrosine kinase Receptor protein-tyrosine kinase Tyrosine-protein kinase Ubiquitin B Ubiquitin C Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein protein-tyrosine-phosphatase protein-tyrosine-phosphatase	A0A286ZJM1 A0A287A231 A0A287A6I2 A0A287AZA7 A0A287AZM9 A0A287B8P3 A0A287BCW9 A0A287BGG6 A0A287BKD5 A0A2C9F3G2 A0A480J4F4 A0A5G2QBP1 A0A5G2R1H6 A0A5G2R2M6 A0A8I8C3K7 A7U5U2 F1RWM5 F1RXX2 F1S911 F1SSQ9 O02705 P0CG68 Q01580 Q684M6	BTC CDC37 CUL5 DTR EGF EGFR ERBB2 ERBB3 ERBB4 EREG HBEGF HEGFL HSP90A HSP90AA1 HSPCA MATK NRG1 NRG2 NRG3 PTPN12 PTPN18 RPS27A STUB1 UBA52 UBB UBC	Sus scrofa (pig)
Integrin cell surface interactions	Basigin CD44 antigen Cadherin-1 Cartilage oligomeric matrix protein Collagen alpha-1(XVI) chain Collagen alpha-2(IX) chain Collagen type IV alpha 1 chain Collagen type IV alpha 2 chain Collagen type IV alpha 3 chain Collagen type IV alpha 4 chain Collagen type IX alpha 1 chain Collagen type IX alpha 3 chain Collagen type XIII alpha 1 chain Collagen type XVIII alpha 1 chain Fibrinogen alpha chain Fibrinogen beta chain Fibrinogen gamma chain Fibronectin Integrin alpha-4 isoform 1 preproprotein Integrin alpha-5 Integrin alpha-9 Integrin beta Integrin beta Integrin beta Integrin beta Integrin beta Integrin beta Integrin beta Integrin subunit alpha 10 Integrin subunit alpha 11 Integrin subunit alpha 1 Integrin subunit alpha 2 Integrin subunit alpha 2b Integrin subunit alpha 3 Integrin subunit alpha 6 Integrin subunit alpha 8 Integrin subunit alpha D Integrin subunit alpha E Integrin subunit alpha L Integrin subunit alpha M Integrin subunit alpha V Integrin-binding sialoprotein Intercellular adhesion molecule 1 Intercellular adhesion molecule 2 Intercellular adhesion molecule 4 Intercellular adhesion molecule 5 Junctional adhesion molecule 2 Junctional adhesion molecule 3 Junctional adhesion molecule A Leukocyte surface antigen CD47 Lumican Mucosal addressin cell adhesion molecule 1 isoform a Osteopontin Platelet and endothelial cell adhesion molecule 1 Platelet endothelial cell adhesion molecule Tenascin C Tenascin N Thrombospondin 1 VWFA domain-containing protein Vascular cell adhesion molecule 1 Vitronectin	A0A286ZIL9 A0A286ZJF0 A0A286ZTM0 A0A287AAG8 A0A287AD51 A0A287AI56 A0A287AK86 A0A287AQ10 A0A287AZ66 A0A287AZF2 A0A287B874 A0A287BIH5 A0A480VGP1 A0A5G2QD63 A0A5G2QGZ8 A0A5G2QUU1 A0A5G2QVP2 A0A5G2QY29 A0A5G2QYR6 A0A5G2R3T7 A0A5G2R7K7 A0A5G2R836 A0A5G2REH3 A0A5G2RNE8 A0A5K1V6L8 A0A8W4FC88 A0A8W4FCC2 A0A8W4FP23 A9X6R3 F1RLL9 F1RQY8 F1RRC1 F1RSK4 F1RT62 F1RW86 F1RX36 F1RX37 F1S3J9 F1S3K0 F1S3K1 F1S567 F1S708 F1S902 F1SGT4 F1SMF4 F1SNP0 F1SQ09 F1SR53 F1SS24 F1SS26 I3L5Z1 I3LCD8 I3LUI4 K7GQ83 K7GS31 K9IVL5 P14287 P48819 Q2V6R9 Q95242 Q9GKE8	BSG CD44 CD47 CDH1 COL13A1 COL16A1 COL18A1 COL4A1 COL4A2 COL4A3 COL4A4 COL9A1 COL9A2 COL9A3 COMP F11R FGA FGB FGG FN1 IBSP ICAM1 ICAM2 ICAM4 ICAM5 ITGA1 ITGA10 ITGA11 ITGA2 ITGA2B ITGA3 ITGA4 ITGA5 ITGA6 ITGA8 ITGA9 ITGAD ITGAE ITGAL ITGAM ITGAV ITGB1 ITGB2 ITGB3 ITGB5 ITGB6 ITGB7 ITGB8 JAM2 JAM3 LUM MADCAM1 OPN PECAM1 SPP1 THBS1 TNC TNN VCAM1 VTN	Sus scrofa (pig)
Interleukin-7 signaling	Bromodomain and WD repeat domain containing 1 Cytokine receptor-like factor 2 Histone H3 Histone H3 Insulin receptor substrate 1 Insulin receptor substrate 2 Interleukin 2 receptor gamma Interleukin-7 receptor subunit alpha Interleukin-7 Phosphatidylinositol 3-kinase regulatory subunit alpha isoform 2 Phosphatidylinositol 3-kinase regulatory subunit beta SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 Signal transducer and activator of transcription 3 Signal transducer and activator of transcription Signal transducer and activator of transcription Signal transducer and activator of transcription Tyrosine-protein kinase Tyrosine-protein kinase	A0A0A0MY60 A0A286ZJQ0 A0A286ZLI2 A0A286ZSF3 A0A287ARN1 A0A287B726 A0A2C9F3G4 E7CR01 F1RVA0 F1S916 F1SKR9 I3LLF1 K7GLC0 K7GSE8 K7GT64 Q19S50 Q76KD0 Q9N2G6	BRWD1 CRLF2 H3C12 H3C14 H3C15 H3C4 H3C6 HIST1H3E IL2RG IL7 IL7R IRS1 IRS2 JAK1 JAK3 LOC110257900 PIK3R1 PIK3R2 SMARCA4 STAT3 STAT5A STAT5B stat5B	Sus scrofa (pig)
Toll Like Receptor 4 (TLR4) Cascade	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma Bactericidal permeability-increasing protein CD180 antigen Integrin beta Integrin subunit alpha M Lipopolysaccharide-binding protein Lymphocyte antigen 86 Lymphocyte antigen 96 Monocyte differentiation antigen CD14 TIR domain-containing adapter molecule 2 Toll-like receptor 4 dynamin GTPase dynamin GTPase dynamin GTPase	A0A287A869 A0A287AK86 A0A287AN09 A0A287B5Y6 A0A287B8X7 A0A287BLV6 A0A287BMU9 A0A480K9W0 A0A5G2REH3 A2SW51 A7BG67 F1S475 I3LCZ7 Q7YRL4	BPI CD14 CD180 DNM1 DNM2 DNM3 ITGAM ITGB2 LBP LY64 LY86 LY96 PLCG2 TICAM2 TLR4	Sus scrofa (pig)
Antimicrobial peptides	Antibacterial peptide BPI fold containing family A member 2 BPI fold containing family B member 1 BPI fold containing family B member 2 BPI fold containing family B member 4 BPI fold-containing family A member 1 Bactericidal permeability-increasing protein C-type lectin domain-containing protein C-type lectin domain-containing protein Chromogranin-A Clusterin Clusterin Elafin Epididymal peptidase inhibitor Fibrinogen C-terminal domain-containing protein Granulysin Lactotransferrin Liver-expressed antimicrobial peptide 2 Lysozyme C-3 N-acetylmuramoyl-L-alanine amidase Non-secretory ribonuclease Peptidase S1 domain-containing protein Peptidoglycan recognition protein 3 Peptidoglycan recognition protein 4 Peptidoglycan-recognition protein Regenerating islet-derived 3 gamma Uncharacterized protein trypsin	A0A286ZI97 A0A287AE25 A0A287AN19 A0A287BDI2 A0A287BGS7 A0A287BLV6 A0A287BME6 A0A287BQB3 A0A5G2QHA2 A0A5G2QU73 A0A5G2R6C7 A0A5G2RCV2 A0A5G2RIT7 A0A5K1UBC7 A0A5S8KLN1 A0A8X9AES5 A7J149 B8YGC1 C6L245 F1SD66 F1SFU8 F1SNX2 K7GS01 K7GSX9 P12069 Q29125 Q29549 Q6YT39	BPI BPIFA1 BPIFA2 BPIFB1 BPIFB2 BPIFB4 CHGA CLU EPPIN GNLY LEAP2 LOC100154047 LOC100520832 LOC100624628 LOC102163838 LOC110255221 LOC110260309 LTF PGLYRP1 PGLYRP2 PGLYRP3 PGLYRP4 PMAP-36 PRSS2 REG3G try	Sus scrofa (pig)	G49108TO
Molecules associated with elastic fibres	Bone morphogenetic protein 10 Bone morphogenetic protein 2 Bone morphogenetic protein 4 Bone morphogenetic protein 7 (Osteogenic protein 1) EGF containing fibulin extracellular matrix protein 2 Fibulin-5 Growth differentiation factor 5 Integrin beta Integrin beta Integrin beta Integrin beta Integrin beta Integrin subunit alpha 8 Integrin subunit alpha V Latent transforming growth factor beta binding protein 1 Latent transforming growth factor beta binding protein 3 Latent transforming growth factor beta binding protein 4 Microfibril associated protein 2 Microfibril associated protein 4 Microfibril associated protein 5 Transforming growth factor beta-1 proprotein Transforming growth factor beta-3 proprotein Transforming growth factor beta-3 proprotein Transforming growth factor beta Vitronectin	A0A286ZV08 A0A286ZWQ1 A0A286ZZE2 A0A287A7C6 A0A287AZ66 A0A287AZP0 A0A287BIH5 A0A287BIU2 A0A5G2QNS3 A0A5G2R2Y0 A0A5G2R7K7 A0A5K1V6L8 A0A8W4FF41 A5GFN2 A7LJT9 A9X6R3 F1RRJ9 F1RW86 F1S4W8 F1SD87 K7GQ83 K7GSJ9 P07200 P15203 P48819	BMP10 BMP2 BMP4 BMP7 EFEMP2 FBLN5 GDF5 ITGA8 ITGAV ITGB1 ITGB3 ITGB5 ITGB6 ITGB8 LTBP1 LTBP3 LTBP4 MFAP2 MFAP4 MFAP5 TGFB1 TGFB2 TGFB3 VTN bmp4	Sus scrofa (pig)
TNFR1-induced proapoptotic signaling	Baculoviral IAP repeat containing 2 FAS-associated death domain protein Inhibitor of nuclear factor kappa B kinase subunit epsilon Putative inhibitor of apoptosis RBR-type E3 ubiquitin transferase RING-type E3 ubiquitin transferase RanBP-type and C3HC4-type zinc finger-containing protein 1 Receptor interacting serine/threonine kinase 1 Spermatogenesis-associated protein 2 TANK binding kinase 1 TNF receptor-associated factor Tumor necrosis factor receptor superfamily member 1A Tumor necrosis factor receptor type 1-associated DEATH domain protein Tumor necrosis factor Ubiquitin carboxyl-terminal hydrolase 4 Ubiquitin carboxyl-terminal hydrolase CYLD Ubiquitin carboxyl-terminal hydrolase Ubiquitin carboxyl-terminal hydrolase ubiquitinyl hydrolase 1 ubiquitinyl hydrolase 1 ubiquitinyl hydrolase 1	A0A286ZI91 A0A286ZVH7 A0A286ZYB8 A0A287AL42 A0A287AQJ4 A0A287AUG2 A0A287B5E3 A0A287BGB4 A0A287BPE4 A0A287BRT1 F1RVZ4 F1S196 F1S6A4 F1S7J3 F1SDG3 I3LH37 I3LI16 M9MMN5 O62640 P23563 Q56VC2	BIRC2 CYLD FADD IKBKE MIB2 OTUD1 OTUD7B PIAP RBCK1 RIPK1 RNF31 SPATA2 TBK1 TNF TNFA TNFAIP3 TNFRSF1A TNFRSF6 TNFSF2 TRADD TRAF2 USP2 USP21 USP4	Sus scrofa (pig)
TNFR1-induced NF-kappa-B signaling pathway	Baculoviral IAP repeat containing 2 IkappaB kinase Inhibitor of nuclear factor kappa-B kinase subunit alpha Mitogen-activated protein kinase kinase kinase 7 NF-kappa-B essential modulator Optineurin Putative inhibitor of apoptosis RBR-type E3 ubiquitin transferase RanBP-type and C3HC4-type zinc finger-containing protein 1 Receptor interacting serine/threonine kinase 1 Small ribosomal subunit protein RACK1 Spermatogenesis-associated protein 2 TGF-beta activated kinase 1 (MAP3K7) binding protein 1 TGF-beta activated kinase 1 (MAP3K7) binding protein 2 TGF-beta activated kinase 1 (MAP3K7) binding protein 3 TNF receptor-associated factor TNF receptor-associated factor Tumor necrosis factor receptor superfamily member 1A Tumor necrosis factor receptor type 1-associated DEATH domain protein Tumor necrosis factor Ubiquitin carboxyl-terminal hydrolase 4 Ubiquitin carboxyl-terminal hydrolase CYLD Ubiquitin carboxyl-terminal hydrolase Ubiquitin carboxyl-terminal hydrolase ubiquitinyl hydrolase 1 ubiquitinyl hydrolase 1 ubiquitinyl hydrolase 1	A0A286ZI91 A0A286ZVH7 A0A286ZYB8 A0A287A5Q1 A0A287AQJ4 A0A287AUG2 A0A287BGB4 A0A287BPE4 A0A287BRT1 A0A481CGW8 A9QT41 B0LXP5 F1RVZ4 F1S196 F1S6A4 F1S7J3 F1S7S1 F1S8V5 F1SDG3 F1SME2 I3LH37 I3LI16 K7GLB8 O62640 P23563 P63246 Q7YS99	BIRC2 CHUK CYLD GNB2L1 IKBKB IKBKG MAP3K7 OPTN OTUD1 OTUD7B PIAP RACK1 RBCK1 RIPK1 RNF31 SPATA2 TAB1 TAB2 TAB3 TAK1b TNF TNFA TNFAIP3 TNFRSF1A TNFSF2 TRADD TRAF1 TRAF2 USP2 USP21 USP4	Sus scrofa (pig)
TNF receptor superfamily (TNFSF) members mediating non-canonical NF-kB pathway	B-cell activating factor Baculoviral IAP repeat containing 2 CD40 ligand Lymphotoxin beta receptor Lymphotoxin-alpha Lymphotoxin-beta Mitogen-activated protein kinase kinase kinase 14 Putative inhibitor of apoptosis TNF receptor superfamily member 11a TNF receptor superfamily member 12A TNF receptor superfamily member 13C TNF receptor-associated factor TNF receptor-associated factor TNF superfamily member 11 TNF superfamily member 12 Tumor necrosis factor receptor superfamily member 5	A0A287AJ47 A0A287AWB6 A0A5G2Q934 A0A8W4FAU5 A0A8W4FCV1 A0MTC9 F1RJX1 F1RR25 F1RVZ4 I3L7R8 I3L871 I3LH37 K7GN73 O62640 P26445 Q8SQ34	BIRC2 CD40 CD40LG LTA LTB LTBR MAP3K14 PIAP TNFB TNFRSF11A TNFRSF12A TNFRSF13C TNFRSF5 TNFSF1 TNFSF11 TNFSF12 TNFSF13B TRAF2 TRAF3	Sus scrofa (pig)
TNFR2 non-canonical NF-kB pathway	26S protease regulatory subunit 4 26S proteasome non-ATPase regulatory subunit 11 26S proteasome non-ATPase regulatory subunit 13 26S proteasome non-ATPase regulatory subunit 1 26S proteasome non-ATPase regulatory subunit 2 26S proteasome non-ATPase regulatory subunit 3 26S proteasome non-ATPase regulatory subunit 4 26S proteasome non-ATPase regulatory subunit 6 26S proteasome non-ATPase regulatory subunit 8 26S proteasome non-ATPase regulatory subunit 9 26S proteasome regulatory subunit 8 B-cell activating factor Baculoviral IAP repeat containing 2 CD40 ligand Lymphotoxin beta receptor Lymphotoxin-alpha Lymphotoxin-beta Mitogen-activated protein kinase kinase kinase 14 Proteasome 20S subunit alpha 2 Proteasome 26S subunit, ATPase 3 Proteasome 26S subunit, ATPase 6 Proteasome 26S subunit, non-ATPase 14 Proteasome 26S subunit, non-ATPase 7 Proteasome activator complex subunit 1 Proteasome activator complex subunit 2 Proteasome activator complex subunit 3 Proteasome activator complex subunit 4 Proteasome inhibitor PI31 subunit Proteasome subunit alpha type Proteasome subunit alpha type Proteasome subunit alpha type Proteasome subunit alpha type Proteasome subunit alpha type Proteasome subunit alpha type Proteasome subunit beta type-7 Proteasome subunit beta Proteasome subunit beta Proteasome subunit beta Proteasome subunit beta Proteasome subunit beta Putative inhibitor of apoptosis TNF receptor superfamily member 11a TNF receptor superfamily member 12A TNF receptor superfamily member 13C TNF receptor superfamily member 1B TNF receptor-associated factor TNF receptor-associated factor TNF superfamily member 11 TNF superfamily member 12 Tumor necrosis factor receptor superfamily member 5 Tumor necrosis factor Uncharacterized protein	A0A286ZLP7 A0A286ZN52 A0A286ZS34 A0A287AEH0 A0A287AJ47 A0A287APQ3 A0A287AWB6 A0A287B5Q7 A0A287BG14 A0A287BPP9 A0A287BRR7 A0A287BRV0 A0A288CG47 A0A480JRT9 A0A5G2Q934 A0A5G2QI19 A0A5G2QL81 A0A5G2QSU8 A0A5G2R6X9 A0A8W4FAU5 A0A8W4FCV1 A0A8W4FHK5 A0A8W4FNV3 A0MTC9 A1XQU1 F1RJX1 F1RKW8 F1RPQ3 F1RR25 F1RVZ4 F1RXA7 F1S9C7 F1SBA5 F1SGF1 F1SGM3 F1SMW9 F2Z5J1 F2Z5K2 F2Z5N0 I3L7R8 I3L871 I3LH37 I3LP81 K7GN73 O62640 P23563 P26445 P61291 P62197 Q2PYM7 Q64L94 Q8SQ34	BIRC2 CD40 CD40LG LMP2 LTA LTB LTBR MAP3K14 PIAP PRORP PSMA1 PSMA2 PSMA4 PSMA5 PSMA6 PSMA7 PSMA8 PSMB1 PSMB10 PSMB11 PSMB3 PSMB7 PSMB9 PSMC1 PSMC3 PSMC5 PSMC6 PSMD1 PSMD11 PSMD13 PSMD14 PSMD2 PSMD3 PSMD4 PSMD6 PSMD7 PSMD8 PSMD9 PSME1 PSME2 PSME3 PSME4 PSMF1 TNF TNFA TNFB TNFRSF11A TNFRSF12A TNFRSF13C TNFRSF1B TNFRSF5 TNFSF1 TNFSF11 TNFSF12 TNFSF13B TNFSF2 TRAF2 TRAF3	Sus scrofa (pig)
Regulation of necroptotic cell death	Baculoviral IAP repeat containing 2 Caspase-8 E2 ubiquitin-conjugating enzyme E3 ubiquitin-protein ligase CHIP FAS-associated death domain protein Flotillin-1 Flotillin Heat shock protein HSP 90-alpha Heat shock protein HSP 90-alpha Hsp90 co-chaperone Cdc37 Mixed lineage kinase domain like pseudokinase Polyubiquitin-C Programmed cell death 6 interacting protein Putative inhibitor of apoptosis Receptor interacting serine/threonine kinase 1 Syndecan binding protein TNF receptor-associated factor Tumor necrosis factor receptor type 1-associated DEATH domain protein Ubiquitin B Ubiquitin C Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein non-specific serine/threonine protein kinase	A0A287AG10 A0A287AH24 A0A287ALN0 A0A287AZA7 A0A287BGG6 A0A287BPE4 A0A287BRT1 A0A2C9F3G2 A0A5G2QUT6 A0A5G2R6P0 A0A8I8C3K7 A7U5U2 F1RVZ4 F1S911 F1SGQ6 I3LH37 O02705 O62640 P0CG68 Q56VC2 Q56VC3 Q684M6 Q767L6	BIRC2 CASP8 CDC37 FADD FLOT1 FLOT2 HSP90A HSP90AA1 HSPCA MLKL PDCD6IP PIAP RIPK1 RIPK3 RPS27A SDCBP STUB1 TNFRSF6 TRADD TRAF2 UBA52 UBB UBC UBE2L3	Sus scrofa (pig)
Regulation of TNFR1 signaling	Baculoviral IAP repeat containing 2 CAP-Gly domain-containing linker protein 3 Caspase 9 Caspase-8 E2 ubiquitin-conjugating enzyme E2 ubiquitin-conjugating enzyme E3 ubiquitin-protein ligase CHIP FAS-associated death domain protein IkappaB kinase Inhibitor of nuclear factor kappa B kinase subunit epsilon Inhibitor of nuclear factor kappa-B kinase subunit alpha MAP kinase-activating death domain protein MAPK activated protein kinase 2 NF-kappa-B essential modulator Optineurin Polyubiquitin-C Putative inhibitor of apoptosis RBR-type E3 ubiquitin transferase RING-type E3 ubiquitin transferase RanBP-type and C3HC4-type zinc finger-containing protein 1 Receptor interacting serine/threonine kinase 1 Serine/threonine-protein kinase Signal peptide peptidase like 2A Signal peptide peptidase like 2B Small ribosomal subunit protein RACK1 Spermatogenesis-associated protein 2 TANK binding kinase 1 TNF receptor-associated factor TNF receptor-associated factor Tax1 binding protein 1 Tumor necrosis factor receptor superfamily member 1A Tumor necrosis factor receptor type 1-associated DEATH domain protein Tumor necrosis factor Ubiquitin B Ubiquitin C Ubiquitin carboxyl-terminal hydrolase 4 Ubiquitin carboxyl-terminal hydrolase CYLD Ubiquitin carboxyl-terminal hydrolase Ubiquitin carboxyl-terminal hydrolase Ubiquitin conjugating enzyme E2 D3 Ubiquitin-conjugating enzyme E2 D2 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein ubiquitinyl hydrolase 1 ubiquitinyl hydrolase 1 ubiquitinyl hydrolase 1	A0A286ZI91 A0A286ZVH7 A0A286ZYB8 A0A287A5Q1 A0A287AL42 A0A287AQJ4 A0A287AUG2 A0A287AZA7 A0A287B5E3 A0A287B9E9 A0A287BGB4 A0A287BGG6 A0A287BPE4 A0A287BRT1 A0A288CFV1 A0A2C9F3G2 A0A5G2QUT6 A0A5G2R1D9 A0A8W4FES8 A7U5U2 A9QT41 F1RFR1 F1RLF4 F1RVZ4 F1RYM5 F1S196 F1S6A4 F1S7J3 F1S8G9 F1S8V5 F1S911 F1SDG3 F1SME2 F1SUV9 I3LH37 I3LI16 K7GLC2 M9MMN5 O62640 P0CG68 P23563 P63246 Q06AA8 Q56VC2 Q56VC3 Q7YS99	BIRC2 CASP8 CASP9 CHUK CLIP3 CYLD FADD GNB2L1 IKBKB IKBKE IKBKG MADD MAPKAPK2 MIB2 OPTN OTUD1 OTUD7B PIAP RACK1 RBCK1 RIPK1 RNF31 RPS27A SPATA2 SPPL2A SPPL2B STUB1 TAX1BP1 TBK1 TNF TNFA TNFAIP3 TNFRSF1A TNFRSF6 TNFSF2 TRADD TRAF1 TRAF2 UBA52 UBB UBC UBE2D1 UBE2D2 UBE2D3 UBE2L3 ULK1 USP2 USP21 USP4	Sus scrofa (pig)
Activated NTRK2 signals through PLCG1	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma Brain-derived neurotrophic factor Neurotrophin-4	F1RIN3 F1SDV6 P14082	BDNF NTF4 PLCG1	Sus scrofa (pig)
Activated NTRK2 signals through FRS2 and FRS3	Brain-derived neurotrophic factor Growth factor receptor bound protein 2 Neurotrophin-4 SOS Ras/Rac guanine nucleotide exchange factor 1	A0A286ZUQ0 B6E241 F1RIN3 P14082	BDNF GRB2 NTF4 SOS1	Sus scrofa (pig)
NTRK2 activates RAC1	Brain-derived neurotrophic factor Dedicator of cytokinesis 3 Ras-related C3 botulinum toxin substrate 1 Tyrosine-protein kinase Fyn	A0A287AKJ4 A0A8W4FI56 A1Y2K1 P14082	BDNF DOCK3 FYN RAC1	Sus scrofa (pig)
Downstream TCR signaling	26S protease regulatory subunit 4 26S proteasome non-ATPase regulatory subunit 11 26S proteasome non-ATPase regulatory subunit 13 26S proteasome non-ATPase regulatory subunit 1 26S proteasome non-ATPase regulatory subunit 2 26S proteasome non-ATPase regulatory subunit 3 26S proteasome non-ATPase regulatory subunit 4 26S proteasome non-ATPase regulatory subunit 6 26S proteasome non-ATPase regulatory subunit 8 26S proteasome non-ATPase regulatory subunit 9 26S proteasome regulatory subunit 8 3-phosphoinositide-dependent protein kinase 1 B-cell CLL/lymphoma 10 Caspase recruitment domain family member 11 Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein IkappaB kinase Inhibitor of nuclear factor kappa-B kinase subunit alpha MALT1 paracaspase MHC class II DR-alpha MHC class II antigen MHC class II histocompatibility antigen SLA-DRB1 Mitogen-activated protein kinase kinase kinase 7 NF-kappa-B essential modulator NF-kappa-B inhibitor alpha Nuclear factor NF-kappa-B p105 subunit Phosphatase and tensin homolog Phosphatidylinositol 3-kinase regulatory subunit alpha isoform 2 Phosphatidylinositol 3-kinase regulatory subunit beta Proteasome 20S subunit alpha 2 Proteasome 26S subunit, ATPase 3 Proteasome 26S subunit, ATPase 6 Proteasome 26S subunit, non-ATPase 14 Proteasome 26S subunit, non-ATPase 7 Proteasome activator complex subunit 1 Proteasome activator complex subunit 2 Proteasome activator complex subunit 3 Proteasome activator complex subunit 4 Proteasome inhibitor PI31 subunit Proteasome subunit alpha type Proteasome subunit alpha type Proteasome subunit alpha type Proteasome subunit alpha type Proteasome subunit alpha type Proteasome subunit alpha type Proteasome subunit beta type-7 Proteasome subunit beta Proteasome subunit beta Proteasome subunit beta Proteasome subunit beta Proteasome subunit beta RELA proto-oncogene, NF-kB subunit Receptor-interacting serine/threonine-protein kinase 2 SLA class II histocompatibility antigen, DQ haplotype D alpha chain SLA-DQ beta1 domain T-cell surface glycoprotein CD3 delta chain T-cell surface glycoprotein CD3 epsilon chain T-cell surface glycoprotein CD3 gamma chain T-cell surface glycoprotein CD3 zeta chain T-cell surface glycoprotein CD4 TGF-beta activated kinase 1 (MAP3K7) binding protein 2 TNF receptor-associated factor 6 Tyrosine-protein kinase UBC core domain-containing protein Uncharacterized protein Uncharacterized protein phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase phosphatidylinositol-4,5-bisphosphate 3-kinase phosphatidylinositol-4,5-bisphosphate 3-kinase	A0A286ZKB7 A0A286ZLP7 A0A286ZN52 A0A286ZS34 A0A286ZUJ9 A0A286ZV67 A0A287A3X6 A0A287A5Q1 A0A287ABR0 A0A287AC24 A0A287AEH0 A0A287APQ3 A0A287AT33 A0A287AVR3 A0A287B5Q7 A0A287B968 A0A287BF11 A0A287BG14 A0A287BPP9 A0A287BQ31 A0A287BRR7 A0A287BRV0 A0A288CG47 A0A480JRT9 A0A5G2QCN4 A0A5G2QI19 A0A5G2QL81 A0A5G2QSU8 A0A5G2QZC6 A0A5G2R6X9 A0A5K1UB41 A0A8W4F9V5 A0A8W4FBN9 A0A8W4FHK5 A0A8W4FJW4 A0A8W4FNK4 A0A8W4FNV3 A0A8W4FP49 A0A8X9AEI7 A0A8X9AEU9 A1XQU1 A7XP20 A7XUJ6 A9QT41 B0LXP5 F1RKW8 F1RPQ3 F1RXA7 F1S6S1 F1S7S1 F1S8V5 F1S916 F1S975 F1S9C7 F1SBA5 F1SGF1 F1SGM3 F1SKR9 F1SMW9 F1SV94 F2Z5H1 F2Z5J1 F2Z5K2 F2Z5N0 F6PVF4 I3L556 I3LAQ5 K7GL70 K7GQH5 K7GS60 P15981 P61291 P62197 Q08353 Q2PYM7 Q5PXD3 Q64L94 Q764N2 Q7YQ94 Q85ZW4	BCL10 CARD11 CD247 CD3D CD3E CD3G CD4 CHUK DRA HLA-DRA IKBA IKBKB IKBKG INPP5D LCK LMP2 LOC100153139 MALT1 MAP3K7 NFKB1 NFKBIA PDPK1 PIK3CA PIK3CB PIK3R1 PIK3R2 PRORP PSMA1 PSMA2 PSMA4 PSMA5 PSMA6 PSMA7 PSMA8 PSMB1 PSMB10 PSMB11 PSMB3 PSMB7 PSMB9 PSMC1 PSMC3 PSMC5 PSMC6 PSMD1 PSMD11 PSMD13 PSMD14 PSMD2 PSMD3 PSMD4 PSMD6 PSMD7 PSMD8 PSMD9 PSME1 PSME2 PSME3 PSME4 PSMF1 PTEN RELA RIPK2 SLA-DQA SLA-DQA1 SLA-DQB1 SLA-DR SLA-DRA SLA-DRA1 SLA-DRB1 TAB2 TAK1b TRAF6 UBE2NL	Sus scrofa (pig)
Apoptotic execution phase	B-cell receptor-associated protein Caspase-8 Dynamin-1-like protein non-specific serine/threonine protein kinase	A0A287B0C4 A0A287BMW9 F1S2A8 Q56VC3	BCAP31 CASP8 DNM1L STK24	Sus scrofa (pig)
Pyroptosis	BCL2 associated X, apoptosis regulator Caspase 1, apoptosis-related cysteine peptidase Caspase-4 Charged multivesicular body protein 2B Charged multivesicular body protein 2a Charged multivesicular body protein 4C Charged multivesicular body protein 6 Charged multivesicular body protein 7 Cytochrome c domain-containing protein Cytochrome c domain-containing protein Cytochrome c domain-containing protein Cytochrome c domain-containing protein Cytochrome c domain-containing protein Cytochrome c domain-containing protein Cytochrome c domain-containing protein Cytochrome c domain-containing protein Cytochrome c Gasdermin E Gasdermin-D Granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1) Interleukin-1 alpha Interleukin-1 beta Interleukin-18 Interleukin-18 Multifunctional fusion protein Multifunctional fusion protein Multifunctional fusion protein Multifunctional fusion protein Multifunctional fusion protein Multifunctional fusion protein	A0A286ZMX3 A0A286ZQJ2 A0A286ZTT0 A0A287A1F6 A0A287AFR7 A0A287B6X4 A0A287BRB4 A0A288CG12 A0A2C9F3A1 A0A5G2QU46 A0A5G2RHT4 A0A8W4F7C9 A0A8W4FBV5 A0A8W4FDZ8 A0A8W4FGL8 A0A8W4FGU7 F1RHI4 F1RZY6 F1SEV7 F1ST94 F1SUB9 F1SV36 I3LCB9 I3LNY8 I3LSS2 M3VK03 O19073 P18430 P26889 P62895	BAX CASP1 CHMP2A CHMP2B CHMP4C CHMP6 CHMP7 CYC CYCS GSDMD GSDME GZMB IGIF IL18 IL1A IL1B IL1B2 LOC100519295 LOC100522842 LOC100522887 LOC100621347 LOC100739590 LOC110255300 LOC110258125 LOC110258578 LOC110259156	Sus scrofa (pig)
Downregulation of TGF-beta receptor signaling	BMP and activin membrane-bound inhibitor homolog E3 ubiquitin-protein ligase CHIP E3 ubiquitin-protein ligase Mothers against decapentaplegic homolog 3 Mothers against decapentaplegic homolog Mothers against decapentaplegic homolog Polyubiquitin-C Prostate transmembrane protein, androgen induced 1 Serine/threonine-protein kinase receptor TGF-beta receptor type-1 Transforming growth factor beta-1 proprotein Ubiquitin B Ubiquitin C Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein protein-tyrosine-phosphatase	A0A287ATZ7 A0A287AZA7 A0A287BBB7 A0A287BE69 A0A287BGG6 A0A287BLR9 A0A287BQ73 A0A2C9F3G2 A0A5G2RC56 A7U5U2 E9LHE5 F1CK19 F1S911 P07200 P0CG68 P84024	BAMBI MADH3 MTMR4 PMEPA1 RPS27A SMAD2 SMAD3 SMAD7 SMURF2 STUB1 Smad7 TGFB1 TGFBR1 TGFBR2 UBA52 UBB UBC bambi	Sus scrofa (pig)
Lactose synthesis	Alpha-lactalbumin Beta-1,4-galactosyltransferase Solute carrier family 2, facilitated glucose transporter member 1	A0A287BG16 P18137 P20303	B4GALT1 GLUT1 LALBA SLC2A1	Sus scrofa (pig)	G58161NS G74621DY
N-Glycan antennae elongation	Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase A Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase B Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase C Alpha-2,8-sialyltransferase 8B Alpha-2,8-sialyltransferase 8F Beta-1,4-galactosyltransferase 5 Beta-1,4-galactosyltransferase Beta-1,4-galactosyltransferase Beta-1,4-galactosyltransferase Beta-1,4-galactosyltransferase Beta-1,4-galactosyltransferase CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 4 isoform 4 MGAT4 family member C ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3 beta-galactoside alpha-(2,6)-sialyltransferase	A0A1S6M251 A0A286ZSQ8 A0A286ZZR3 A0A287AS89 A0A287B0E4 A0A287BG16 A0A287BJP1 A0A5G2QU42 F1RWB6 F1S1A6 F1S444 F1S6H2 F1SPA3 M1FW61 Q6ITT3	B4GALT1 B4GALT2 B4GALT3 B4GALT4 B4GALT5 B4GALT6 MGAT4A MGAT4B MGAT4C ST3GAL4 ST6GAL1 ST8SIA2 ST8SIA3 ST8SIA6 ST8Sia 2	Sus scrofa (pig)	G81533KY
Lewis blood group biosynthesis	Alpha-(1,3)-fucosyltransferase Alpha-(1,3)-fucosyltransferase Alpha2,3-sialyltransferase CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 4 isoform 4 Fucosyltransferase Fucosyltransferase Fucosyltransferase Galactoside alpha-(1,2)-fucosyltransferase 2 Glycosyltransferase 2-like domain-containing protein Hexosyltransferase Hexosyltransferase Hexosyltransferase ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 6 Type 2 lactosamine alpha-2,3-sialyltransferase	A0A287AMU7 A0A287B633 A0A287B819 A0A287BIT3 A0A287BS10 A0A8W4FN42 F1RS05 F1RZT4 F1S6H2 F1SAB1 F1SBU3 I3L7N4 Q10982 Q70D54	B3GALT1 B3GALT2 B3GALT4 FUT10 FUT11 FUT2 FUT4 FUT7 LOC100513844 LOC110255214 ST3GAL-III ST3GAL3 ST3GAL4 ST3GAL6 ST6GALNAC6	Sus scrofa (pig)	G39211DH G81971FM G83633HB G90387AM G98173LG
O-linked glycosylation	Beta-1,4-glucuronyltransferase 1 Dolichyl-phosphate-mannose--protein mannosyltransferase Dolichyl-phosphate-mannose--protein mannosyltransferase Dystroglycan 1 Hexosyltransferase LARGE xylosyl- and glucuronyltransferase 1 LARGE xylosyl- and glucuronyltransferase 2 Protein O-linked-mannose beta-1,2-N-acetylglucosaminyltransferase Protein O-linked-mannose beta-1,4-N-acetylglucosaminyltransferase 2 Protein O-mannose kinase	A0A287AB08 A0A287AH62 A0A287AMB9 A0A287BBR1 A0A287BKQ3 A0A480F6A1 F1RUS9 F1S2M9 F1SI95 F1SRD5	B3GALNT2 B4GAT1 DAG1 LARGE1 LARGE2 POMGNT1 POMGNT2 POMK POMT1 POMT2	Sus scrofa (pig)
DAP12 interactions	Beta-2-microglobulin C-type lectin domain family 5 member A C-type lectin domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Immunoglobulin C1-set domain-containing protein Killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 1 MHC class I antigen 2 MHC class I antigen 3 MHC class I antigen 6 MHC class I antigen 7 MHC class I antigen 8 Natural killer cells antigen CD94 Sialic acid binding Ig like lectin 15 Sialic acid-binding Ig-like lectin 5 Signal regulatory protein alpha TYRO protein tyrosine kinase-binding protein Triggering receptor expressed on myeloid cells 1 Triggering receptor expressed on myeloid cells 2	A0A287AFM5 A0A287AIY8 A0A287AJS8 A0A287B0R8 A0A287B4V1 A0A5G2Q878 A0A5G2R144 A0A5G2R517 A0A5G2RH45 A0A8W4F753 A0A8W4FKP8 A0A8W4FNN4 F1RP86 F1RTG6 F1RUY5 F1SQ28 I3LTK3 M9MMN6 Q07717 Q6TYI6 Q9GLF3 Q9TU45	B2M CLEC5A CLECSF5 DAP12 KIR2DL1 KLRD1 LOC100513601 LOC100513863 LOC100523789 MDL1 NCR2 SIGLEC14 SIGLEC15 SIGLEC5 SIRPA SLA-2 SLA-3 SLA-6 SLA-7 SLA-8 TREM1 TREM2 TYROBP	Sus scrofa (pig)

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