GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	March 20, 2024
ECODAB	April 1, 2019

Displaying entries **201 - 225** of **360** in total

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Pathway Name	Protein Name	UniProt ID	Gene Symbol	Organism ▼	GlyTouCan ID
SHC1 events in ERBB4 signaling	Betacellulin Epiregulin GTPase HRas GTPase NRas Growth factor receptor bound protein 2 Neuregulin 2 Neuregulin 3 Pro-neuregulin-1, membrane-bound isoform Proheparin-binding EGF-like growth factor Receptor protein-tyrosine kinase SHC-transforming protein 1 SOS Ras/Rac guanine nucleotide exchange factor 1 small monomeric GTPase	A0A286ZJM1 A0A286ZUQ0 A0A287A6I2 A0A287AZM9 A0A287BCW9 A0A5G2QLX0 A0A5G2R1H6 A0A5K1V5Y3 B6E241 F1SSQ9 I3LCQ9 Q01580 Q2MJK3	BTC DTR ERBB4 EREG GRB2 HBEGF HEGFL HRAS KRAS NRAS NRG1 NRG2 NRG3 SHC1 SOS1	Sus scrofa (pig)
TRAF6 mediated NF-kB activation	Advanced glycosylation end-product specific receptor Amyloid-beta A4 protein Amyloid-beta precursor protein IkappaB kinase Inhibitor of nuclear factor kappa-B kinase subunit alpha NF-kappa-B essential modulator NF-kappa-B inhibitor alpha NF-kappa-B inhibitor-interacting Ras-like protein 1 isoform X1 NF-kappa-B inhibitor-interacting Ras-like protein 2 Nuclear factor NF-kappa-B p100 subunit isoform X1 Nuclear factor NF-kappa-B p105 subunit Protein S100-A12 Protein S100-B RELA proto-oncogene, NF-kB subunit S100 calcium binding protein A12	A0A286ZTE6 A0A287A5Q1 A0A287AVR3 A0A5S6H0X2 A0A8W4FCZ9 A0A8W4FET6 A9QT41 F1S8V5 F2Z555 F6PVF4 I3L911 K9IW82 P79307 P80310 Q08353	A4 AD1 AGER APP CHUK IKBA IKBKB IKBKG NFKB1 NFKB2 NFKB2_tv2 NFKBIA NKIRAS1 NKIRAS2 RELA S100A12 S100B	Sus scrofa (pig)
RHOC GTPase cycle	A-kinase anchor protein 13 ATP binding cassette subfamily D member 3 Active breakpoint cluster region-related protein Acyl-CoA-binding domain-containing protein 5 Anillin, actin binding protein BCR activator of RhoGEF and GTPase Caveolae associated protein 1 Caveolin Citron Rho-interacting kinase Coiled-coil domain containing 187 Complement component 1 Q subcomponent-binding protein, mitochondrial DEP domain containing 1B Delta(14)-sterol reductase LBR Diaphanous related formin 1 Diaphanous related formin 3 Dishevelled associated activator of morphosis 1 Flotillin-1 Flotillin Formin like 2 Formin like 3 Guanine nucleotide exchange factor DBS isoform X2 IQ motif containing GTPase activating protein 3 Junction plakoglobin Junction plakoglobin Lectin, mannose binding 1 MCF.2 cell line derived transforming sequence Macoilin Melanoma cell adhesion molecule Myosin IXB Oligophrenin-1 Phosphatidylinositol 3-kinase regulatory subunit alpha isoform 2 Phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 1 Rac GTPase activating protein 1 Rho GDP-dissociation inhibitor 1 Rho GTPase activating protein 18 Rho GTPase activating protein 1 Rho GTPase activating protein 21 Rho GTPase activating protein 39 Rho GTPase activating protein 5 Rho GTPase-activating protein 26 Rho GTPase-activating protein 35 Rho GTPase-activating protein 7 Rho guanine nucleotide exchange factor 10 like Rho guanine nucleotide exchange factor 10 Rho guanine nucleotide exchange factor 11 Rho guanine nucleotide exchange factor 12 Rho guanine nucleotide exchange factor 17 Rho guanine nucleotide exchange factor 1 Rho guanine nucleotide exchange factor 25 Rho guanine nucleotide exchange factor 28 Rho guanine nucleotide exchange factor 5 Rho-associated protein kinase 2 Rho-associated protein kinase Rho-related GTP-binding protein RhoC Rhotekin Stomatin Tight junction protein 2 Transferrin receptor protein 1 Transferrin receptor protein 1 Transforming protein RhoA VAMP associated protein B and C Vang-like protein Vav guanine nucleotide exchange factor 2 Vesicle-associated membrane protein 3 Vesicle-associated membrane protein-associated protein B non-specific serine/threonine protein kinase protein kinase C protein kinase C protein kinase C	A0A0D5BWD2 A0A286ZJQ9 A0A286ZLF6 A0A286ZUE0 A0A286ZZ97 A0A287A7V4 A0A287AAT1 A0A287AIC4 A0A287AJS0 A0A287ALN0 A0A287APG0 A0A287AQA7 A0A287AQX9 A0A287AV56 A0A287AYN9 A0A287AZG0 A0A287B186 A0A287B310 A0A287B8N4 A0A287BEC7 A0A287BF14 A0A287BT99 A0A2C9F3E9 A0A480QRR0 A0A481A732 A0A481BTZ2 A0A5G2QA45 A0A5G2QIS7 A0A5G2QRI9 A0A5G2QXS5 A0A5G2R1A0 A0A5G2R5Z3 A0A5G2REY5 A0A5S6GXI4 A0A8W4FBH6 A0A8W4FG77 A0A8W4FKM4 A0A8W4FMS3 A0A8W4FNA4 A5GFS8 E7EI20 F1RJ64 F1RM07 F1RQ74 F1RSQ1 F1S2Z5 F1SAW7 F1SCI4 F1SEU3 F1SH88 F1SIM2 F1SKH7 F1SKR9 F1SMS8 F1SUT6 I3LBU6 I3LD06 I3LDR4 I3LI20 I3LKY7 I3LQ81 I3LQV1 I3LVS7 M3TYT0 M3VH35 Q2TLZ2 Q767L6 Q8HZV3 Q8WNW3	ABCD3 ABR ACBD5 AKAP13 ANLN ARHGAP1 ARHGAP18 ARHGAP21 ARHGAP26 ARHGAP35 ARHGAP39 ARHGAP5 ARHGDIA ARHGEF1 ARHGEF10 ARHGEF10L ARHGEF11 ARHGEF12 ARHGEF17 ARHGEF25 ARHGEF28 ARHGEF5 BCR C1QBP CAV1 CAVIN1 CIT DAAM1 DEPDC1B DIAPH1 DIAPH3 DLC1 FLOT1 FLOT2 FMNL2 FMNL3 IQGAP3 JUP Jup LBR LMAN1 MACO1 MCAM MCF2 MCF2L MYO9B OPHN1 PIK3R1 PKN1 PKN2 PKN3 PREX1 RACGAP1 RHOA RHOC ROCK1 ROCK2 RTKN SLK STOM TFRC TJP2 TMEM57 VAMP3 VANGL1 VAPB VAV2	Sus scrofa (pig)
Activated NTRK2 signals through PLCG1	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma Brain-derived neurotrophic factor Neurotrophin-4	F1RIN3 F1SDV6 P14082	BDNF NTF4 PLCG1	Sus scrofa (pig)
Tandem of pore domain in a weak inwardly rectifying K+ channels (TWIK)	Potassium channel subfamily K member Potassium channel subfamily K member Potassium channel subfamily K member	A0A287AWU0 F1RGV1 F1RRI8	KCNK1 KCNK6 KCNK7	Sus scrofa (pig)
RHOBTB1 GTPase cycle	COP9 signalosome complex subunit 2 COP9 signalosome complex subunit 4 Cleavage and polyadenylation specific factor 7 Cullin 3 E3 ubiquitin-protein ligase RBBP6 G protein pathway suppressor 1 Heterogeneous nuclear ribonucleoproteins C1/C2 isoform X1 Phosphodiesterase Rho related BTB domain containing 1 Rho-associated protein kinase 2 Rho-associated protein kinase Serine and arginine repetitive matrix 1 Serine/threonine kinase 38 T-complex protein 1 subunit beta TRA2B Thioredoxin like 1 Unconventional myosin-VI Vimentin	A0A287A2J9 A0A287AAK1 A0A287AL07 A0A287AV47 A0A287B475 A0A5G2QIS7 A0A5G2QW31 A0A5K1ULP5 A7Y521 D0G0C8 F1RKQ8 F1RY93 F1S1X9 I3LK71 K9IVT3 M3TYT0 P02543 Q06AA7	CCT2 COPS2 COPS4 CPSF7 CUL3 GPS1 HNRNPC MYO6 PDE5A RBBP6 RHOBTB1 ROCK1 ROCK2 SRRM1 STK38 TRA2B TXNL1 VIM	Sus scrofa (pig)
FasL/ CD95L signaling	Caspase-8 FAS-associated death domain protein Tumor necrosis factor receptor superfamily member 6 Tumor necrosis factor receptor superfamily member 6	F1SCY7 O77736 Q56VC2 Q56VC3	APT1 CASP8 FADD FAS TNFRSF6	Sus scrofa (pig)
TNFs bind their physiological receptors	B-cell activating factor CD27 CD70 molecule EDAR associated death domain Ectodysplasin A receptor Ectodysplasin A Lymphotoxin-alpha TNF receptor superfamily member 13B TNF receptor superfamily member 17 TNF receptor superfamily member 18 TNF receptor superfamily member 1B TNF receptor superfamily member 25 TNF receptor superfamily member 4 TNF receptor superfamily member 9 TNF superfamily member 11 TNF superfamily member 13 TNF superfamily member 15 TNF superfamily member 18 TNF superfamily member 4 TNF superfamily member 9 Tumor necrosis factor receptor superfamily member 11B Tumor necrosis factor receptor superfamily member 1A	A0A286ZPI2 A0A286ZQA0 A0A286ZVH7 A0A287A0L0 A0A287A7B3 A0A5K1VKG5 A0A5S6H780 A0A8W4FAC7 A0A8W4FCJ9 A0A8W4FMJ5 A0MTC9 F1RJX1 F1S746 F1SBT1 F1SU31 I3LDN7 I3LL00 I3LP81 K7GPY3 L7QHB1 P26445 Q4QTJ8	CD27 CD70 EDA EDAR EDARADD LTA TNFB TNFRSF11B TNFRSF13B TNFRSF17 TNFRSF18 TNFRSF1A TNFRSF1B TNFRSF25 TNFRSF4 TNFRSF9 TNFSF1 TNFSF11 TNFSF13 TNFSF13B TNFSF15 TNFSF18 TNFSF4 TNFSF9	Sus scrofa (pig)
Ion transport by P-type ATPases	ATPase 13A1 ATPase Na+/K+ transporting subunit alpha 3 ATPase cation transporting 13A2 Calcium-transporting ATPase Calcium-transporting ATPase Calcium-transporting ATPase Calcium-transporting ATPase Calcium-transporting ATPase Calcium-transporting ATPase Calcium-transporting ATPase Calcium/calmodulin-dependent protein kinase type II subunit delta Calmodulin 3 Cardiac phospholamban Cation-transporting ATPase Cation-transporting ATPase FXYD domain-containing ion transport regulator P-type Cu(+) transporter PDZ domain-containing protein 11 Phospholemman Phospholipid-transporting ATPase Phospholipid-transporting ATPase Phospholipid-transporting ATPase Phospholipid-transporting ATPase Phospholipid-transporting ATPase Phospholipid-transporting ATPase Phospholipid-transporting ATPase Phospholipid-transporting ATPase Phospholipid-transporting ATPase Phospholipid-transporting ATPase Phospholipid-transporting ATPase Phospholipid-transporting ATPase Phospholipid-transporting ATPase Phospholipid-transporting ATPase Potassium-transporting ATPase subunit beta Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 Sarcoplasmic/endoplasmic reticulum calcium ATPase 3 Sodium/potassium-transporting ATPase subunit alpha-2 Sodium/potassium-transporting ATPase subunit alpha Sodium/potassium-transporting ATPase subunit alpha Sodium/potassium-transporting ATPase subunit beta-1 Sodium/potassium-transporting ATPase subunit beta Sodium/potassium-transporting ATPase subunit beta Sorcin calcium/calmodulin-dependent protein kinase calcium/calmodulin-dependent protein kinase calcium/calmodulin-dependent protein kinase	A0A287A226 A0A287AFK3 A0A287AL21 A0A287APC7 A0A287B705 A0A287B7D1 A0A287B7S6 A0A287BAN5 A0A287BCC5 A0A5G2Q8V3 A0A5G2QCQ9 A0A5G2QQF7 A0A5G2QSB0 A0A5G2QWK6 A0A5G2RAC3 A0A5G2RDL8 A0A5K1U0J0 A0A5K1VCX5 A0A8W4FK37 A0A8W4FN13 A0A8X9AEX2 D2WKD8 F1RL74 F1RM59 F1RQ73 F1S340 F1S3S6 F1SDH8 F1SFG8 F1SM35 F1SNN7 F1SQH3 F1ST41 F1SUR9 I3LIK9 I3LMB3 I3LN55 I3LUR3 K7GQ24 O77696 P05027 P11607 P18434 P61013 Q6QA76 Q95266	ATP10A ATP10B ATP10D ATP11A ATP11B ATP11C ATP12A ATP13A1 ATP13A2 ATP13A4 ATP13A5 ATP1A2 ATP1A3 ATP1B1 ATP1B2 ATP1B3 ATP2A1 ATP2A2 ATP2A3 ATP2B1 ATP2B2 ATP2B3 ATP2B4 ATP2C1 ATP2C2 ATP4A ATP4B ATP7A ATP8A1 ATP8A2 ATP8B1 ATP8B2 ATP8B3 ATP8B4 ATP9A ATP9B CALM3 CAMK2A CAMK2B CAMK2D CAMK2G FXYD1 FXYD6 PDZD11 PDZK11 PLM PLN SRI	Sus scrofa (pig)
G alpha (z) signalling events	Adenylate cyclase 3 Adenylate cyclase type 1 Adenylate cyclase type 2 Adenylate cyclase type 4 Adenylate cyclase type 5 Adenylate cyclase type 6 Adenylate cyclase type 7 Adenylate cyclase type 8 Alpha-2A adrenergic receptor Alpha-2B adrenergic receptor Alpha-2C adrenergic receptor G protein subunit alpha z G protein subunit beta 2 G protein subunit beta 3 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 Guanine nucleotide-binding protein subunit beta-5 Guanine nucleotide-binding protein subunit gamma Guanine nucleotide-binding protein subunit gamma Guanine nucleotide-binding protein subunit gamma Guanine nucleotide-binding protein subunit gamma Guanine nucleotide-binding protein subunit gamma Guanine nucleotide-binding protein subunit gamma Guanine nucleotide-binding protein subunit gamma Guanine nucleotide-binding protein subunit gamma Guanine nucleotide-binding protein subunit gamma Guanine nucleotide-binding protein subunit gamma Regulator of G protein signaling 20 Regulator of G-protein signaling 16 Regulator of G-protein signaling 17 adenylate cyclase	A0A286ZLJ8 A0A286ZT06 A0A286ZVN4 A0A287ADM2 A0A287AHC5 A0A287AW90 A0A287AWF4 A0A287B2U1 A0A287B6W0 A0A5G2QFC3 A0A5G2QYS1 A0A5G2R753 A0A8W4FGM1 B9TRW9 F1RLT6 F1RSG7 F1S0T0 F1S668 F1S7X6 F1SDL2 F1SGQ5 F1SLU8 F1SPN5 F1ST77 F2Z4Z8 I3L9P4 I3LFJ1 I3LM81 P18871 Q38PT0	A2AR ADCY1 ADCY2 ADCY3 ADCY4 ADCY5 ADCY6 ADCY7 ADCY8 ADCY9 ADRA2A ADRA2B ADRA2C GNAZ GNB1 GNB2 GNB3 GNB5 GNG10 GNG11 GNG12 GNG3 GNG4 GNG5 GNG7 GNG8 LOC100621431 LOC110255211 RGS16 RGS17 RGS20	Sus scrofa (pig)
Iron uptake and transport	Broad substrate specificity ATP-binding cassette transporter ABCG2 Broad substrate specificity ATP-binding cassette transporter ABCG2 Cullin 1 Cullin-associated NEDD8-dissociated protein 1 Cytoplasmic aconitate hydratase F-box/LRR-repeat protein 5 FLVCR heme transporter 1 Ferritin Ferritin Heme oxygenase 1 Hephaestin Iron-responsive element-binding protein 2 Iron-responsive element-binding protein 2 Lipocalin 2 NEDD8 Plasma membrane ascorbate-dependent reductase CYBRD1 Polyubiquitin-C Proton-coupled folate transporter S-phase kinase-associated protein 1 Serotransferrin Solute carrier family 11 member 2 Solute carrier family 22 member 17 Ubiquitin B Ubiquitin C Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	A0A286ZMM6 A0A287AE63 A0A287AL10 A0A287ARU4 A0A287AZA7 A0A287BJ65 A0A287BLE8 A0A287BQT2 A0A288CFV5 A0A2C9F3G2 A0A5S6GWJ4 A0A8W4FQ04 A7U5U2 B2ZPK1 B3VKQ2 F1RKU5 F1S2X6 F1S5E2 F1S911 F1S9E2 F2Z5R6 I3L9X9 K7GSZ6 P0CG68 P32394 Q8MIB3	ABCG2 ABCG2A ACO1 BMDP CAND1 CUL1 CYBRD1 FBXL5 FLVCR1 FTH1 FTL HEPH HMOX1 IREB2 LCN2 NEDD8 RPS27A SKP1 SLC11A2 SLC22A17 SLC46A1 TF UBA52 UBB UBC	Sus scrofa (pig)
GRB2 events in ERBB2 signaling	Betacellulin Epiregulin GTPase HRas GTPase NRas Growth factor receptor bound protein 2 Neuregulin 2 Neuregulin 3 Pro-neuregulin-1, membrane-bound isoform Proheparin-binding EGF-like growth factor Receptor protein-tyrosine kinase Receptor protein-tyrosine kinase SOS Ras/Rac guanine nucleotide exchange factor 1 small monomeric GTPase	A0A286ZJM1 A0A286ZUQ0 A0A287A6I2 A0A287AZM9 A0A287BCW9 A0A5G2QLX0 A0A5G2R1H6 B6E241 F1RWM5 F1SSQ9 I3LCQ9 Q01580 Q2MJK3	BTC DTR ERBB2 ERBB4 EREG GRB2 HBEGF HEGFL HRAS KRAS NRAS NRG1 NRG2 NRG3 SOS1	Sus scrofa (pig)
Nuclear signaling by ERBB4	Estrogen receptor Gamma-secretase subunit APH-1 Gamma-secretase subunit APH-1 Nicastrin Presenilin-2 Presenilin Presenilin Receptor protein-tyrosine kinase Signal transducer and activator of transcription Tyrosine-protein kinase WW domain-containing oxidoreductase Yes1 associated transcriptional regulator	A0A0A0MY60 A0A286ZNK4 A0A286ZSI3 A0A287ALG6 A0A2C9F398 A0A5G2RBN0 F1S3K9 F1SSQ9 I3L8R2 K7GPR7 Q0MS45 Q29040	APH1A APH1B ERBB4 ESR ESR1 NCSTN NR3A1 PSEN1 PSEN2 SRC STAT5A WWOX YAP1	Sus scrofa (pig)
MyD88 cascade initiated on plasma membrane	Evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial Mitogen-activated protein kinase kinase kinase 1 TNF receptor-associated factor 6	A0A287ABQ5 A7XUJ6 F1SA28	ECSIT MAP3K1 TRAF6	Sus scrofa (pig)
MET interacts with TNS proteins	Hepatocyte growth factor receptor Hepatocyte growth factor Integrin beta Tensin 3 Tensin-4	F1RXE4 F1SB93 F1ST78 K7GQ83 Q2QLE0	HGF ITGB1 MET TNS3 TNS4	Sus scrofa (pig)
RHOB GTPase cycle	A-kinase anchor protein 13 Actin, alpha cardiac muscle 1 Active breakpoint cluster region-related protein Anillin, actin binding protein BCR activator of RhoGEF and GTPase Caveolae associated protein 1 Caveolin Citron Rho-interacting kinase DEP domain containing 1B Diaphanous related formin 1 Diaphanous related formin 3 Dishevelled associated activator of morphosis 1 Epithelial cell transforming 2 Flotillin-1 Flotillin Guanine nucleotide exchange factor DBS isoform X2 IQ motif containing GTPase activating protein 3 Junction plakoglobin Junction plakoglobin MCF.2 cell line derived transforming sequence Melanoma cell adhesion molecule Myosin IXA Myosin IXB Neuroepithelial cell transforming 1 Oligophrenin-1 Phosphatidylinositol 3-kinase regulatory subunit alpha isoform 2 Phosphatidylinositol 3-kinase regulatory subunit beta Phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 1 Protocadherin 7 RHOB Rac GTPase activating protein 1 Rho GDP dissociation inhibitor gamma Rho GTPase activating protein 1 Rho GTPase activating protein 21 Rho GTPase activating protein 39 Rho GTPase activating protein 5 Rho GTPase-activating protein 26 Rho GTPase-activating protein 35 Rho GTPase-activating protein 7 Rho guanine nucleotide exchange factor 10 like Rho guanine nucleotide exchange factor 10 Rho guanine nucleotide exchange factor 11 Rho guanine nucleotide exchange factor 12 Rho guanine nucleotide exchange factor 17 Rho guanine nucleotide exchange factor 1 Rho guanine nucleotide exchange factor 25 Rho guanine nucleotide exchange factor 28 Rho guanine nucleotide exchange factor 2 Rho guanine nucleotide exchange factor 3 Rho guanine nucleotide exchange factor 5 Rho-associated protein kinase 2 Rho-associated protein kinase Rhophilin-2 Rhotekin StAR related lipid transfer domain containing 8 Stomatin Synaptosomal-associated protein Tight junction protein 2 Transferrin receptor protein 1 Transferrin receptor protein 1 Vang-like protein Vav guanine nucleotide exchange factor 2 Vesicle-associated membrane protein 3 non-specific serine/threonine protein kinase protein kinase C protein kinase C protein kinase C	A0A286ZJQ9 A0A286ZLF6 A0A286ZUE0 A0A286ZZ97 A0A287A7V4 A0A287AAM5 A0A287AAT1 A0A287AHK8 A0A287AIC4 A0A287AIM9 A0A287AJS0 A0A287ALN0 A0A287APG0 A0A287AQX9 A0A287AV13 A0A287AV56 A0A287AYN9 A0A287AZG0 A0A287B310 A0A287B6A9 A0A287B7D4 A0A287B8N4 A0A287BEC7 A0A287BF14 A0A287BP24 A0A287BPQ3 A0A287BT99 A0A2C9F3E9 A0A480QRR0 A0A481A732 A0A481BTZ2 A0A5G2QA45 A0A5G2QIS7 A0A5G2QRI9 A0A5G2QXC2 A0A5G2QXS5 A0A5G2R1A0 A0A5G2R5Z3 A0A5S6GXI4 A0A8W4F696 A0A8W4FG77 A0A8W4FMS3 A0A8W4FNA4 F1RJ64 F1RM07 F1RQ74 F1RSQ1 F1S916 F1SAW7 F1SCI4 F1SEU3 F1SH88 F1SIM2 F1SKH7 F1SKR9 F1SUT6 I3LBU6 I3LD06 I3LDR4 I3LKY7 I3LQ81 I3LRU1 M3TYT0 Q06AT8 Q767L6 Q8HZV3 Q8WNW3	ABR ACTC1 AKAP13 ANLN ARHGAP1 ARHGAP21 ARHGAP26 ARHGAP35 ARHGAP39 ARHGAP5 ARHGDIG ARHGEF1 ARHGEF10 ARHGEF10L ARHGEF11 ARHGEF12 ARHGEF17 ARHGEF2 ARHGEF25 ARHGEF28 ARHGEF3 ARHGEF5 BCR CAV1 CAVIN1 CIT DAAM1 DEPDC1B DIAPH1 DIAPH3 DLC1 ECT2 FLOT1 FLOT2 IQGAP3 JUP Jup MCAM MCF2 MCF2L MYO9A MYO9B NET1 OPHN1 PCDH7 PIK3R1 PIK3R2 PKN1 PKN2 PKN3 PREX1 RACGAP1 RHOB RHPN2 ROCK1 ROCK2 RTKN SLK SNAP23 STARD8 STOM TFRC TJP2 VAMP3 VANGL1 VAV2	Sus scrofa (pig)
MTOR signalling	14-3-3 protein beta/alpha AKT1 substrate 1 Late endosomal/lysosomal adaptor, MAPK and MTOR activator 2 Neutral amino acid transporter 9 Ragulator complex protein LAMTOR1 Ragulator complex protein LAMTOR3 Ragulator complex protein LAMTOR4 Ragulator complex protein LAMTOR5 Ras homolog, mTORC1 binding Ras-related GTP-binding protein Ras-related GTP-binding protein Ras-related GTP-binding protein Ras-related GTP-binding protein Regulatory associated protein of MTOR complex 1 Serine/threonine-protein kinase mTOR Target of rapamycin complex subunit LST8	A0A286ZKD7 A0A287ASH4 A0A287AYR5 A0A287BPX7 A0A480VPY5 A0A5G2RAT2 A0A5G2RET7 A0A8W4FBM1 F1RFA8 F1RHR8 F1RHU2 F2Z518 F2Z5Q5 I3L942 I3LK13 Q66X52	AKT1S1 LAMTOR1 LAMTOR2 LAMTOR3 LAMTOR4 LAMTOR5 MLST8 MTOR RHEB RPTOR RRAGA RRAGB RRAGC RRAGD SLC38A9 YWHAB	Sus scrofa (pig)
UCH proteinases	26S protease regulatory subunit 4 26S proteasome non-ATPase regulatory subunit 11 26S proteasome non-ATPase regulatory subunit 13 26S proteasome non-ATPase regulatory subunit 1 26S proteasome non-ATPase regulatory subunit 2 26S proteasome non-ATPase regulatory subunit 3 26S proteasome non-ATPase regulatory subunit 4 26S proteasome non-ATPase regulatory subunit 6 26S proteasome non-ATPase regulatory subunit 8 26S proteasome non-ATPase regulatory subunit 9 26S proteasome regulatory subunit 8 ADRM1 26S proteasome ubiquitin receptor ASXL transcriptional regulator 1 ASXL transcriptional regulator 2 Actin like 6A Actin, cytoplasmic 1 Actin-related protein 5 Actin-related protein 8 BRCA1 associated RING domain 1 Chromatin-remodeling ATPase INO80 Forkhead box K1 Forkhead box K2 Histone H2A Histone H2A Histone H2A Histone H2A Histone H2A Histone H2A Histone H2A Histone H2A Histone H2A Host cell factor C1 INO80 complex subunit B INO80 complex subunit C INO80 complex subunit D INO80 complex subunit E Lysine demethylase 1B Methyl-CpG binding domain protein 5 Methyl-CpG binding domain protein 6 Microspherule protein 1 NEDD8 Nuclear factor related to kappaB binding protein Polyubiquitin-C Proteasome 20S subunit alpha 2 Proteasome 26S subunit, ATPase 3 Proteasome 26S subunit, ATPase 6 Proteasome 26S subunit, non-ATPase 14 Proteasome 26S subunit, non-ATPase 7 Proteasome activator complex subunit 1 Proteasome activator complex subunit 2 Proteasome activator complex subunit 3 Proteasome activator complex subunit 4 Proteasome inhibitor PI31 subunit Proteasome subunit alpha type Proteasome subunit alpha type Proteasome subunit alpha type Proteasome subunit alpha type Proteasome subunit alpha type Proteasome subunit alpha type Proteasome subunit beta type-7 Proteasome subunit beta Proteasome subunit beta Proteasome subunit beta Proteasome subunit beta Proteasome subunit beta RuvB-like helicase SUMO peptidase family member, NEDD8 specific TCF3 fusion partner Ubiquitin B Ubiquitin C Ubiquitin carboxyl-terminal hydrolase isozyme L1 Ubiquitin carboxyl-terminal hydrolase isozyme L5 Ubiquitin carboxyl-terminal hydrolase Ubiquitin carboxyl-terminal hydrolase Ubiquitin carboxyl-terminal hydrolase Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein Uncharacterized protein YY1 transcription factor	A0A286ZLP7 A0A286ZN52 A0A286ZS34 A0A287AE63 A0A287AEH0 A0A287ALX5 A0A287APQ3 A0A287ARK3 A0A287AZA7 A0A287B0L6 A0A287B5Q7 A0A287B8Q3 A0A287BCD1 A0A287BFK0 A0A287BG14 A0A287BPP9 A0A287BRR7 A0A287BRV0 A0A288CG47 A0A2C9F3G2 A0A480JJE7 A0A480JRT9 A0A480SJY5 A0A480TR54 A0A5G2QI19 A0A5G2QL81 A0A5G2QNC6 A0A5G2QSU8 A0A5G2R6X9 A0A5G2RET1 A0A8W4F7H9 A0A8W4F948 A0A8W4FHK5 A0A8W4FNV3 A1XQU1 A7U5U2 F1RI50 F1RKW8 F1RNI4 F1RPL1 F1RPQ3 F1RUH6 F1RXA7 F1S012 F1S0H8 F1S6F0 F1S911 F1S9C7 F1SAA9 F1SBA5 F1SDL7 F1SDX1 F1SGC8 F1SGF1 F1SGM3 F1SHB3 F1SHE0 F1SL57 F1SLH2 F1SMW9 F1SSV0 F2Z587 F2Z5J1 F2Z5K2 F2Z5L2 F2Z5L5 F2Z5N0 I3L5H4 I3L742 K9IVK7 K9IVT5 P0CG68 P61291 P62197 Q06AT3 Q2PYM7 Q64L94 Q6QAQ1 Q6SEG5	ACTB ACTL6A ACTR5 ACTR8 ADRM1 ASXL1 ASXL2 BAP1 BARD1 FOXK1 FOXK2 H2AC10 H2AC11 H2AC12 H2AC14 H2AC17 H2AC18 H2AC19 H2AC20 H2AC25 H2AC4 H2AC6 H2AC7 H2AC8 HCFC1 INO80 INO80B INO80C INO80D INO80E KDM1B LMP2 LOC110261482 MBD5 MBD6 MCRS1 NEDD8 NFRKB PRORP PSMA1 PSMA2 PSMA4 PSMA5 PSMA6 PSMA7 PSMA8 PSMB1 PSMB10 PSMB11 PSMB3 PSMB7 PSMB9 PSMC1 PSMC3 PSMC5 PSMC6 PSMD1 PSMD11 PSMD13 PSMD14 PSMD2 PSMD3 PSMD4 PSMD6 PSMD7 PSMD8 PSMD9 PSME1 PSME2 PSME3 PSME4 PSMF1 RPS27A RUVBL1 SENP8 TFPT UBA52 UBB UBC UCHL1 UCHL3 UCHL5 YY1	Sus scrofa (pig)
Regulation by c-FLIP	Caspase 9 Caspase-8 FAS-associated death domain protein Receptor interacting serine/threonine kinase 1 TNF receptor-associated factor Tumor necrosis factor receptor superfamily member 10A Tumor necrosis factor receptor superfamily member 10A Tumor necrosis factor receptor superfamily member 6 Tumor necrosis factor receptor superfamily member 6 Tumor necrosis factor receptor type 1-associated DEATH domain protein	A0A286ZQG3 A0A287BPE4 A0A287BRT1 F1RVZ4 F1SCY7 F1SUV9 I3L5L0 O77736 Q56VC2 Q56VC3	APT1 CASP8 CASP9 FADD FAS LOC100624226 LOC100737977 RIPK1 TNFRSF6 TRADD TRAF2	Sus scrofa (pig)
Platelet sensitization by LDL	Apolipoprotein B LDL receptor related protein 8 Mitogen-activated protein kinase 14 Platelet and endothelial cell adhesion molecule 1 Platelet endothelial cell adhesion molecule Protein phosphatase 2 regulatory subunit B'gamma Protein phosphatase 2 scaffold subunit Abeta Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform Serine/threonine-protein phosphatase Tyrosine-protein phosphatase non-receptor type	A0A287A9P4 A0A287AG13 A0A287APB4 A0A287BGB1 A0A287BHS8 A0A480LMF4 E7CXS0 F1RQR5 F1RX68 F1S2V7 K7GS31 P54612 P67776 Q95242	APOB ApoER2 LRP8 MAPK14 PECAM1 PPP2CA PPP2CB PPP2R1A PPP2R1B PPP2R5A PPP2R5B PPP2R5C PPP2R5D PTPN11	Sus scrofa (pig)
Lactose synthesis	Alpha-lactalbumin Beta-1,4-galactosyltransferase Solute carrier family 2, facilitated glucose transporter member 1	A0A287BG16 P18137 P20303	B4GALT1 GLUT1 LALBA SLC2A1	Sus scrofa (pig)	G58161NS G74621DY
RIPK1-mediated regulated necrosis	Flotillin-1 Flotillin Mixed lineage kinase domain like pseudokinase Programmed cell death 6 interacting protein Receptor interacting serine/threonine kinase 1 Syndecan binding protein non-specific serine/threonine protein kinase	A0A287AG10 A0A287AH24 A0A287ALN0 A0A287BRT1 A0A5G2R6P0 F1SGQ6 Q767L6	FLOT1 FLOT2 MLKL PDCD6IP RIPK1 RIPK3 SDCBP	Sus scrofa (pig)
Orexin and neuropeptides FF and QRFP bind to their respective receptors	Hypocretin neuropeptide precursor Neuropeptide FF receptor 1 Neuropeptide FF receptor 2 Orexin receptor type 2 Orexin/Hypocretin receptor type 1 Pyroglutamylated RFamide peptide receptor	A0A287A138 F1RUN6 F1S1T5 F1SUD0 O62809 O77668	HCRT HCRTR1 HCRTR2 NPFFR1 NPFFR2 ORX OX PPOX QRFPR	Sus scrofa (pig)
RAC3 GTPase cycle	Abl interactor 1 Abl interactor 2 Active breakpoint cluster region-related protein Adhesion molecule with Ig like domain 2 Amino acid transporter Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2 BAR/IMD domain containing adaptor protein 2 like 1 BCR activator of RhoGEF and GTPase BRICK1 subunit of SCAR/WAVE actin nucleating complex Brain-specific angiogenesis inhibitor 1-associated protein 2 CDC42 effector protein 1 Caveolin Cell division control protein 42 homolog Cytochrome b-245 heavy chain Cytochrome b-245 light chain Cytoplasmic FMR1 interacting protein 1 DEP domain containing 1B Dedicator of cytokinesis 10 Delta(14)-sterol reductase LBR Delta-like protein Desmoglein 2 Diaphanous related formin 3 Emerin Extended synaptotagmin 1 FERM domain containing kindlin 2 GIT ArfGAP 1 GIT ArfGAP 2 Granule associated Rac and RHOG effector 1 Integrin beta Lectin, mannose binding 1 MAGUK p55 subfamily member 7 MCF.2 cell line derived transforming sequence Melanoma cell adhesion molecule NADPH oxidase 1 NADPH oxidase 3 NADPH oxidase activator 1 NADPH oxidase organizer 1 NCK associated protein 1 like NHS actin remodeling regulator Nck-associated protein 1 Neutrophil cytosolic factor 1 Neutrophil cytosolic factor 2 Neutrophil cytosolic factor 4 Oligophrenin-1 Phosphatidylinositol 3-kinase regulatory subunit alpha isoform 2 Phosphatidylinositol 3-kinase regulatory subunit beta Phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 1 Progesterone receptor membrane component 2 RNA binding motif protein 39 Rac GTPase activating protein 1 Rac family small GTPase 3 Ragulator complex protein LAMTOR1 Rap guanine nucleotide exchange factor 1 Ras-related protein Rab-7a Rho GTPase activating protein 17 Rho GTPase activating protein 1 Rho GTPase activating protein 21 Rho GTPase activating protein 39 Rho GTPase activating protein 5 Rho GTPase activating protein 6 Rho GTPase-activating protein 15 Rho GTPase-activating protein 26 Rho GTPase-activating protein 35 SLIT and NTRK like family member 3 SLIT and NTRK like family member 5 SLIT-ROBO Rho GTPase activating protein 2 Switching B cell complex subunit SWAP70 Synapse defective Rho GTPase homolog 1 Synaptosomal-associated protein TIAM Rac1 associated GEF 1 Transferrin receptor protein 1 Transferrin receptor protein 1 Tyrosine-protein kinase Vang-like protein Vav guanine nucleotide exchange factor 2 Vesicle-associated membrane protein 3 Wiskott-Aldrich syndrome protein family member YKT6 v-SNARE homolog non-specific serine/threonine protein kinase non-specific serine/threonine protein kinase non-specific serine/threonine protein kinase phosphoinositide 5-phosphatase receptor protein-tyrosine kinase	A0A0U2ETD0 A0A286ZJQ9 A0A286ZMP2 A0A286ZN71 A0A286ZUE0 A0A286ZWQ0 A0A286ZZA8 A0A287A159 A0A287A2E5 A0A287A671 A0A287AHK8 A0A287AIC4 A0A287AJY4 A0A287AR23 A0A287ATF2 A0A287ATV4 A0A287AUX3 A0A287AZB9 A0A287AZG0 A0A287B3E0 A0A287B8N4 A0A287BAQ0 A0A287BEC7 A0A287BG06 A0A287BKM4 A0A287BKX8 A0A287BT99 A0A480IRR7 A0A480KQN9 A0A480P3R5 A0A480TSR9 A0A5G2QA45 A0A5G2QJL5 A0A5G2QQG7 A0A5G2QSN6 A0A5G2QXS5 A0A5G2R098 A0A5G2R0L8 A0A5G2R5Z3 A0A5G2RET7 A0A5K1VSC0 A0A5K1VSS6 A0A5S6GXI4 A0A8W4FA00 A0A8W4FEI6 A0A8W4FJM1 A0A8W4FMS3 F1RFK7 F1RFZ2 F1RJ64 F1RJL1 F1RM07 F1RM08 F1RN87 F1RQ74 F1RSQ1 F1RTW7 F1S0W0 F1S4M1 F1S916 F1SAN7 F1SAW7 F1SB25 F1SGW7 F1SH46 F1SH88 F1SKR9 F1SMS8 F1SNP7 F1SQW0 F1SRN4 F1SUT8 F2Z5S6 I3LD06 I3LDR4 I3LIY8 K7GKS3 K7GN21 K7GQ83 K7GR14 K9IWB5 M3VH35 Q007T2 Q8HZV3	ABI1 ABI2 ABL2 ABR AMIGO2 ARAP2 ARAP3 ARHGAP1 ARHGAP15 ARHGAP17 ARHGAP21 ARHGAP26 ARHGAP35 ARHGAP39 ARHGAP5 ARHGAP6 BAIAP2 BAIAP2L1 BCR BRK1 CAV1 CDC42 CDC42EP1 CYBA CYFIP1 DEPDC1B DIAPH3 DOCK10 DSG2 EMD EPHA2 ESYT1 FERMT2 GARRE1 GIT1 GIT2 GP91-PHOX ITGB1 JAG1 KIAA0355 LAMTOR1 LBR LMAN1 MCAM MCF2 MPP7 NCF1 NCF2 NCF4 NCKAP1 NCKAP1L NHS NOX1 NOX3 NOXA1 NOXO1 OCRL OPHN1 PAK1 PAK2 PGRMC2 PIK3R1 PIK3R2 PREX1 RAB7A RAC3 RACGAP1 RAPGEF1 RBM39 SLC1A5 SLITRK3 SLITRK5 SNAP23 SRGAP2 SWAP70 SYDE1 TFRC TIAM1 TRIO VAMP3 VANGL1 VAV2 WASF2 YKT6	Sus scrofa (pig)
Toll Like Receptor 9 (TLR9) Cascade	Early endosome antigen 1 Phosphatidylinositol 3-kinase catalytic subunit type 3 Rabenosyn, RAB effector Toll-like receptor 9 non-specific serine/threonine protein kinase	A0A287AVI7 A0A287BHR8 A0A5G2RJ76 F1SAI0 Q5I2M3	EEA1 PIK3C3 PIK3R4 RBSN TLR9	Sus scrofa (pig)

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