GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	March 20, 2024
ECODAB	April 1, 2019

Displaying entries **201 - 225** of **360** in total

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Pathway Name	Protein Name	UniProt ID ▼	Gene Symbol	Organism	GlyTouCan ID
Na+/Cl- dependent neurotransmitter transporters	Solute carrier family 18 member A1 Solute carrier family 22 member 1 Solute carrier family 22 member 2 Solute carrier family 6 member 18 Solute carrier family 6 member 19 Transporter Transporter Transporter Transporter Transporter Transporter Transporter Transporter Transporter Transporter Transporter Transporter Transporter	A0A286ZR77 A0A287A9U9 A0A287AJD7 A0A287AMT4 A0A287AYA7 A0A480E2J0 A0A5G2QRJ4 A0A5G2QXJ4 A0A5G2RG90 A0A5K1V0Y8 A0A8W4FJT1 F1RF13 F1RL70 F1RYN4 F1S024 I3LKJ8 I3LR93 O02713	OCT2 SLC18A1 SLC22A1 SLC22A2 SLC6A1 SLC6A11 SLC6A12 SLC6A13 SLC6A14 SLC6A15 SLC6A18 SLC6A19 SLC6A2 SLC6A20 SLC6A3 SLC6A5 SLC6A6 SLC6A7 SLC6A9	Sus scrofa (pig)
Erythropoietin activates Phosphoinositide-3-kinase (PI3K)	Erythropoietin receptor Erythropoietin GRB2 associated binding protein 1 Insulin receptor substrate 2 Phosphatidylinositol 3-kinase regulatory subunit alpha isoform 2 Phosphoinositide 3-kinase regulatory subunit 5 Tyrosine-protein kinase JAK2 Tyrosine-protein kinase phosphatidylinositol-4,5-bisphosphate 3-kinase phosphatidylinositol-4,5-bisphosphate 3-kinase phosphatidylinositol-4,5-bisphosphate 3-kinase phosphatidylinositol-4,5-bisphosphate 3-kinase	A0A286ZR76 A0A287B726 A0A5K1UB41 A0A5K1UPW2 A0A8X9AEI7 F1RT53 F1SKR9 I3LJB7 K7GMT0 O19064 P49157 Q9MYZ9	EPO EPOR GAB1 IRS2 JAK2 LYN PIK3CA PIK3CB PIK3CD PIK3CG PIK3R1 PIK3R5	Sus scrofa (pig)
Chemokine receptors bind chemokines	Alveolar macrophage chemotactic factor 2 Atypical chemokine receptor 2 Atypical chemokine receptor 3 Atypical chemokine receptor 4 C motif chemokine receptor 1 C-C chemokine receptor type 10 C-C chemokine receptor type 2 isoform B C-C chemokine receptor type 4 isoform X1 C-C chemokine receptor type 5 C-C chemokine receptor type 9 isoform A C-C motif chemokine 25 C-C motif chemokine 27 C-C motif chemokine 2 C-C motif chemokine 4 C-C motif chemokine ligand 21 C-C motif chemokine receptor 1 C-C motif chemokine receptor 6 C-C motif chemokine C-C motif chemokine C-C motif chemokine C-C motif chemokine C-C motif chemokine C-C motif chemokine C-X-C chemokine receptor type 2 C-X-C chemokine receptor type 2 C-X-C chemokine receptor type 3 C-X-C chemokine receptor type 4 C-X-C chemokine receptor type 6 C-X-C motif chemokine 16 C-X-C motif chemokine 16 C-X-C motif chemokine receptor 5 C-X-C motif chemokine C-X-C motif chemokine C-X-C motif chemokine C-X-C motif chemokine C-X-C motif chemokine Chemokine (C motif) ligand 1 Chemokine C-C motif receptor-like 2 Chemokine receptor 7 Interleukin-8 Platelet basic protein Stromal cell-derived factor 1	A0A286ZR23 A0A287A706 A0A287AV32 A0A287BIL1 A0A287BKA0 A0A5G2QQD0 A0A5G2RL73 A3F9C6 B0FYK2 D0EM41 F1RF20 F1RPV4 F1S1A1 F1S3U3 F1SM08 F1SS04 F1SS05 G8XRI4 I3LBI5 K7GML5 K7GPC7 K7GPV8 K7GQH9 P22952 P26894 P42831 P43030 Q1WL53 Q2EN89 Q4PR21 Q5K4L1 Q5S1S3 Q6YST0 Q6YT42 Q6YT44 Q6YT47 Q711P4 Q75ZH0 Q75ZH8 Q764M9 Q861S1 Q9GKE2	ACKR2 ACKR3 ACKR4 CCL1 CCL17 CCL2 CCL20 CCL21 CCL22 CCL25 CCL27 CCL3L1 CCL4 CCL5 CCR1 CCR10 CCR2 CCR3 CCR4 CCR5 CCR6 CCR7 CCR9 CCRL1 CCRL2 CCXCR1 CXCL10 CXCL12 CXCL13 CXCL16 CXCL2 CXCL7 CXCL8 CXCL9 CXCR2 CXCR3 CXCR4 CXCR5 CXCR6 IL8 LOC100525396 MIP1B PPBP SCY4A SCYA2 SCYB7 XCL1 XCR1	Sus scrofa (pig)
Sialic acid metabolism	Alpha-2,8-sialyltransferase 8B Alpha-2,8-sialyltransferase 8F Alpha-N-acetylneuraminide alpha-2,8-sialyltransferase Alpha2,3-sialyltransferase Beta-galactosidase Beta-galactoside alpha-2,6-sialyltransferase 2 CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 1 CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 4 isoform 4 CMP-N-acetylneuraminate-poly-alpha-2,8-sialyltransferase CMP-sialic acid transporter isoform X1 Carboxypeptidase Gal-NAc6S Glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase Lactosylceramide alpha-2,3-sialyltransferase N-acetylneuraminate lyase N-acetylneuraminate lyase N-acetylneuraminate synthase N-acetylneuraminic acid phosphatase N-acylneuraminate cytidylyltransferase ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 3 ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 4 ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 5 ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 6 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 5 Sialidase-1 Sialin Type 2 lactosamine alpha-2,3-sialyltransferase alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase beta-galactoside alpha-(2,6)-sialyltransferase exo-alpha-sialidase exo-alpha-sialidase exo-alpha-sialidase	A0A286ZR19 A0A286ZSQ8 A0A286ZZR3 A0A287A0U5 A0A287A537 A0A287A8C8 A0A287ACU7 A0A287AMU7 A0A287ARB7 A0A287B0V1 A0A287BAR8 A0A287BJ72 A0A287BMG4 A0A287BP79 A0A287BS35 A0A480E8L5 A0A480LAY6 A0A8W4FH71 A0A8W4FIM2 A5PF10 F1RRV7 F1RS05 F1RWB6 F1RWP7 F1RZ66 F1S0G0 F1S6H2 F1SM45 F6PZ23 I3LGI9 I3LS82 M1FW61 Q70D54 Q9BEC7	CMAS CTSA GLB1 GNE NANP NANS NEU1 NEU2 NEU3 NEU4 NPL SLC17A5 SLC35A1 ST3GAL-III ST3GAL1 ST3GAL2 ST3GAL3 ST3GAL4 ST3GAL5 ST3GAL6 ST6GAL1 ST6GAL2 ST6GALNAC1 ST6GALNAC2 ST6GALNAC3 ST6GALNAC4 ST6GALNAC5 ST6GALNAC6 ST8SIA1 ST8SIA2 ST8SIA3 ST8SIA4 ST8SIA5 ST8SIA6 ST8Sia 2	Sus scrofa (pig)
Glycosphingolipid catabolism	Alpha-galactosidase Arylsulfatase A Arylsulfatase B Arylsulfatase D Arylsulfatase E (chondrodysplasia punctata 1) Arylsulfatase G Arylsulfatase K Arylsulfatase family member I Arylsulfatase family member J Beta-galactosidase Beta-galactosidase Beta-galactosidase Beta-hexosaminidase Beta-hexosaminidase Carboxypeptidase Ectonucleotide pyrophosphatase/phosphodiesterase 7 Galactocerebrosidase Galactosidase beta 1 like Ganglioside GM2 activator Glucosylceramidase beta 3 Mannose-6-phosphate receptor, cation dependent Neutral ceramidase Non-lysosomal glucosylceramidase Prosaposin Sialidase-1 Sphingomyelin phosphodiesterase 4 Sphingomyelin phosphodiesterase Sulfatase N-terminal domain-containing protein Sulfatase N-terminal domain-containing protein Sulfatase N-terminal domain-containing protein Sulfatase modifying factor 1 Sulfatase modifying factor 2 ceramidase exo-alpha-sialidase exo-alpha-sialidase exo-alpha-sialidase sphingomyelin phosphodiesterase sphingomyelin phosphodiesterase	A0A286ZR19 A0A286ZRI8 A0A286ZTV6 A0A287A0M2 A0A287A7V3 A0A287AGF2 A0A287AXH1 A0A287B239 A0A287B636 A0A287BP79 A0A480LAY6 A0A480QKC9 A0A5G2Q9X4 A0A5G2QVV6 A0A5G2QXG4 A0A5G2QXL0 A0A5G2R907 A0A5G2R9H5 A5PF10 D0G6X8 F1REY9 F1RIU4 F1RK95 F1RL69 F1RMN6 F1RSY4 F1RZ75 F1S048 F1SDZ2 F1SES5 F1SLX0 F1SM45 F1SR82 F1STB6 I3LGI9 I3LM95 I3LRN8 I3LS26	ARSA ARSB ARSD ARSG ARSI ARSJ ARSK ARSL ASAH1 ASAH2 CTSA ENPP7 GALC GBA2 GBA3 GLA GLB1 GLB1L GLB1L2 GLB1L3 GM2A HEXA HEXB LOC100621771 M6PR NEU1 NEU2 NEU3 NEU4 PSAP SMPD1 SMPD2 SMPD3 SMPD4 STS SUMF1 SUMF2	Sus scrofa (pig)	G09546QO G27025MB G58161NS
Pentose phosphate pathway	6-phosphogluconate dehydrogenase, decarboxylating 6-phosphogluconolactonase Glucose-6-phosphate 1-dehydrogenase Phosphoglucomutase 2 Ribokinase Ribulose-phosphate 3-epimerase Sedoheptulokinase Transaldolase Transketolase deoxyribose-phosphate aldolase ribose-5-phosphate isomerase	A0A286ZQY9 A0A286ZS31 A0A287A7K4 A0A287BSL9 A0A5G2QMT1 A0A5G2QR34 A8U4R4 F1RLI9 F1S4K7 F1STC1 Q29593	DERA G6PD PGD PGLS PGM2 RBKS RPE RPIA SHPK TALDO1 TKT tkt	Sus scrofa (pig)	G31080DL
Erythropoietin activates RAS	Erythropoietin receptor Erythropoietin Growth factor receptor bound protein 2 Insulin receptor substrate 2 Proto-oncogene vav Rap guanine nucleotide exchange factor 1 SHC-transforming protein 1 Tyrosine-protein kinase JAK2 Tyrosine-protein kinase	A0A286ZQX2 A0A287B726 A0A5K1V5Y3 B6E241 F1RT53 F1S0W0 O19064 P49157 Q9MYZ9	EPO EPOR GRB2 IRS2 JAK2 LYN RAPGEF1 SHC1 VAV1	Sus scrofa (pig)
Dimerization of procaspase-8	Caspase 9 Caspase-8 FAS-associated death domain protein Receptor interacting serine/threonine kinase 1 TNF receptor-associated factor Tumor necrosis factor receptor superfamily member 10A Tumor necrosis factor receptor superfamily member 10A Tumor necrosis factor receptor superfamily member 6 Tumor necrosis factor receptor superfamily member 6 Tumor necrosis factor receptor type 1-associated DEATH domain protein	A0A286ZQG3 A0A287BPE4 A0A287BRT1 F1RVZ4 F1SCY7 F1SUV9 I3L5L0 O77736 Q56VC2 Q56VC3	APT1 CASP8 CASP9 FADD FAS LOC100624226 LOC100737977 RIPK1 TNFRSF6 TRADD TRAF2	Sus scrofa (pig)
Regulation by c-FLIP	Caspase 9 Caspase-8 FAS-associated death domain protein Receptor interacting serine/threonine kinase 1 TNF receptor-associated factor Tumor necrosis factor receptor superfamily member 10A Tumor necrosis factor receptor superfamily member 10A Tumor necrosis factor receptor superfamily member 6 Tumor necrosis factor receptor superfamily member 6 Tumor necrosis factor receptor type 1-associated DEATH domain protein	A0A286ZQG3 A0A287BPE4 A0A287BRT1 F1RVZ4 F1SCY7 F1SUV9 I3L5L0 O77736 Q56VC2 Q56VC3	APT1 CASP8 CASP9 FADD FAS LOC100624226 LOC100737977 RIPK1 TNFRSF6 TRADD TRAF2	Sus scrofa (pig)
Negative regulation of FGFR4 signaling	E3 ubiquitin-protein ligase CBL Fibroblast growth factor 23 Fibroblast growth factor 9 Fibroblast growth factor receptor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Growth factor receptor bound protein 2 Klotho beta Mitogen-activated protein kinase Mitogen-activated protein kinase Multifunctional fusion protein Polyubiquitin-C Tyrosine-protein phosphatase non-receptor type Ubiquitin B Ubiquitin C Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	A0A286ZQE1 A0A287AFX3 A0A287AXR0 A0A287AZA7 A0A287B3V5 A0A287BGK8 A0A2C9F3G2 A0A480LMF4 A0A480NH74 A0A5G2QUY7 A0A5G2R7G2 A0A5G2RG05 A7U5U2 B6E241 F1RM38 F1RY80 F1S3B8 F1S911 F1SET9 I3L560 I3LR27 P0CG68 Q95L12	CBL FGF1 FGF16 FGF18 FGF19 FGF2 FGF20 FGF23 FGF4 FGF6 FGF8 FGF9 FGFR4 Fgf4 GRB2 KLB MAPK1 MAPK3 PTPN11 RPS27A UBA52 UBB UBC	Sus scrofa (pig)
Negative regulation of FGFR1 signaling	Anosmin 1 E3 ubiquitin-protein ligase CBL Fibroblast growth factor 23 Fibroblast growth factor 9 Fibroblast growth factor receptor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Growth factor receptor bound protein 2 Klotho Mitogen-activated protein kinase Mitogen-activated protein kinase Multifunctional fusion protein Polyubiquitin-C Tyrosine-protein phosphatase non-receptor type Ubiquitin B Ubiquitin C Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	A0A286ZQE1 A0A287AAE4 A0A287AFX3 A0A287AXR0 A0A287AZA7 A0A287BG34 A0A287BGK8 A0A2C9F3G2 A0A480LMF4 A0A480NH74 A0A5G2R7G2 A0A5G2RG05 A7U5U2 B6E241 F1RM38 F1RSR6 F1RY78 F1RY80 F1S911 F1SET9 F1SMG2 K7GQJ1 K7GS84 P0CG68 Q95L12	ANOS1 CBL FGF1 FGF10 FGF2 FGF20 FGF22 FGF23 FGF3 FGF4 FGF5 FGF6 FGF8 FGF9 FGFR1 Fgf4 GRB2 KL MAPK1 MAPK3 PTPN11 RPS27A UBA52 UBB UBC	Sus scrofa (pig)
Negative regulation of MET activity	E3 ubiquitin-protein ligase CBL Endophilin-A2 Epidermal growth factor receptor pathway substrate 15 Growth factor receptor bound protein 2 Hepatocyte growth factor receptor Hepatocyte growth factor-regulated tyrosine kinase substrate Hepatocyte growth factor Leucine rich repeats and immunoglobulin like domains 1 Polyubiquitin-C SH3 domain containing GRB2 like 3, endophilin A3 SH3 domain containing kinase binding protein 1 Signal transducing adaptor molecule 2 Signal transducing adaptor molecule Tyrosine-protein phosphatase non-receptor type Tyrosine-protein phosphatase non-receptor type Ubiquitin B Ubiquitin C Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein ubiquitinyl hydrolase 1	A0A286ZQE1 A0A287A000 A0A287AZA7 A0A287BAQ6 A0A287BNZ9 A0A2C9F3G2 A0A5G2Q9Y0 A0A5G2QFX7 A0A5G2RE13 A7U5U2 B6E241 F1RYL9 F1S7L8 F1S911 F1SB93 F1SFR8 F1SHW8 I3LPZ5 P0CG68 Q2QLE0	CBL EPS15 GRB2 HGF HGS LRIG1 MET PTPN1 PTPN2 RPS27A SH3GL1 SH3GL3 SH3KBP1 STAM STAM2 UBA52 UBB UBC USP8	Sus scrofa (pig)
TGF-beta receptor signaling activates SMADs	E3 ubiquitin-protein ligase CBL Integrin beta Integrin beta Integrin beta Integrin beta Integrin beta Integrin subunit alpha 8 Integrin subunit alpha V Latent transforming growth factor beta binding protein 1 Latent transforming growth factor beta binding protein 3 Latent transforming growth factor beta binding protein 4 Mothers against decapentaplegic homolog 3 Mothers against decapentaplegic homolog 4 Mothers against decapentaplegic homolog NEDD8 Serine/threonine-protein kinase receptor TGF-beta receptor type-1 Transforming growth factor beta receptor 3 Transforming growth factor beta-1 proprotein Transforming growth factor beta-3 proprotein Transforming growth factor beta-3 proprotein Transforming growth factor beta Ubiquitin conjugating enzyme E2 M Zinc finger FYVE domain-containing protein furin peptidylprolyl isomerase	A0A286ZQE1 A0A286ZV08 A0A286ZWQ1 A0A287AE63 A0A287AZ66 A0A287BE69 A0A287BIH5 A0A287BIQ9 A0A287BLR9 A0A287BNE4 A0A287BPI7 A0A5G2R7K7 A0A5G2RC56 A0A5K1V6L8 A0A8W4FF41 A9X6R3 F1RMJ1 F1RRJ9 F1RW86 K7GQ83 K7GSJ9 P07200 P15203 P84024 Q2VTP6 Q9GKQ9	CBL FKBP1A FURIN ITGA8 ITGAV ITGB1 ITGB3 ITGB5 ITGB6 ITGB8 LTBP1 LTBP3 LTBP4 MADH3 MADH4 NEDD8 SMAD2 SMAD3 SMAD4 TGFB1 TGFB2 TGFB3 TGFBR1 TGFBR2 TGFBR3 UBE2M ZFYVE9	Sus scrofa (pig)
Scavenging by Class A Receptors	Apolipoprotein A-I Apolipoprotein B Apolipoprotein E Calreticulin Collectin-11 Endoplasmin MBL associated serine protease 1	A0A286ZQC7 A0A287AFA5 A0A287AG13 A0A5G2QE59 F1RM45 I3LEW0 P28491	APOA1 APOB APOE CALR COLEC11 HSP90B1 MASP1	Sus scrofa (pig)	G70323CJ G82576YO
HDL clearance	Apolipoprotein A-I High density lipoprotein binding protein Scavenger receptor class B member 1 Scavenger receptor class B member 1	A0A286ZQC7 A0A286ZVH8 A0A8W4FKC7 Q8SQC1	APOA1 HDLBP SCARB1	Sus scrofa (pig)
Scavenging by Class B Receptors	Apolipoprotein A-I Apolipoprotein B Platelet glycoprotein 4 Scavenger receptor class B member 1 Scavenger receptor class B member 1	A0A286ZQC7 A0A286ZVH8 A0A287AG13 Q3HUX1 Q8SQC1	APOA1 APOB CD36 SCARB1	Sus scrofa (pig)
Post-translational protein phosphorylation	Adipose triglyceride lipase Albumin Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase A Alpha-2-HS-glycoprotein Alpha-L-fucosidase Alpha-fetoprotein Ameloblastin Amelogenin Amyloid beta like protein 2 Amyloid-beta A4 protein Amyloid-beta precursor protein Anoctamin Antithrombin-III Apolipoprotein A-I Apolipoprotein A-II Apolipoprotein A-V Apolipoprotein B Apolipoprotein E Apolipoprotein L3 isoform 1 Apolipoprotein L3 isoform X1 BPI fold containing family B member 2 Bone morphogenetic protein 15 Bone morphogenetic protein 4 CCN family member 1 Cadherin-2 Chordin like 1 Coagulation factor V Complement C3 Complement C4A (Rodgers blood group) Cystatin C Cytoskeleton associated protein 4 Dentin matrix acidic phosphoprotein 1 Disintegrin and metalloproteinase domain-containing protein 10 DnaJ homolog subfamily C member 3 Endoplasmin Extracellular serine/threonine protein kinase FAM20C isoform X1 FAM20A golgi associated secretory pathway pseudokinase Fibrinogen alpha chain Fibrinogen gamma chain Fibroblast growth factor 23 Fibronectin Follistatin-related protein 1 Galectin Glucosidase 2 subunit beta Glypican-3 Golgi membrane protein 1 Growth arrest specific 6 Heparin cofactor 2 Histidine rich calcium binding protein Insulin like growth factor binding protein 7 Insulin-like growth factor-binding protein 1 Insulin-like growth factor-binding protein 3 Insulin-like growth factor-binding protein 4 Insulin-like growth factor-binding protein 5 Inter-alpha-trypsin inhibitor heavy chain H2 Interleukin-6 Kinectin 1 Kininogen 1 Latent transforming growth factor beta binding protein 1 MIA SH3 domain ER export factor 3 Macrophage colony-stimulating factor 1 Matrilin 3 Matrix extracellular phosphoglycoprotein Matrix remodeling-associated protein 8 Melanotransferrin Membrane bound transcription factor peptidase, site 1 Menin Metalloproteinase inhibitor 1 Multiple EGF like domains 6 Nucleobindin-1 Osteopontin Proprotein convertase subtilisin/kexin type 9 Protein disulfide-isomerase A6 Protein disulfide-isomerase Reticulocalbin-1 SPARC like 1 Secreted phosphoprotein 24 Secretogranin-1 Secretogranin-2 Secretogranin-3 Serine protease 23 Serotransferrin Serpin family A member 1 Stanniocalcin-2 Sulfhydryl oxidase Syndecan Tenascin C Tenascin N Trans-Golgi network integral membrane protein 2 Transmembrane protein 132A Uteroferrin associated basic protein-2 VGF nerve growth factor inducible Versican core protein Vitamin K-dependent protein C Wolframin ER transmembrane glycoprotein [Wnt protein] O-palmitoleoyl-L-serine hydrolase von Willebrand factor A domain-containing protein 1	A0A286ZQC7 A0A286ZRX5 A0A286ZTE6 A0A286ZU78 A0A286ZWQ1 A0A286ZZH4 A0A287A5V7 A0A287AF70 A0A287AFA5 A0A287AG13 A0A287AKS6 A0A287ALA1 A0A287AXR0 A0A287AYJ5 A0A287B049 A0A287B0E4 A0A287BAY9 A0A287BDE8 A0A287BFZ3 A0A287BHU3 A0A287BP22 A0A287BPE2 A0A288CFV5 A0A480P2S5 A0A480Y2E3 A0A481BCM9 A0A481BLI9 A0A5G2Q797 A0A5G2QCF0 A0A5G2QCL1 A0A5G2QN69 A0A5G2QS80 A0A5G2QUR1 A0A5G2QUU1 A0A5G2QXX3 A0A5G2R599 A0A5G2R6R2 A0A5G2RA54 A0A5G2RDD7 A0A5G2RIA8 A0A5G2RIT7 A0A8W4FB62 A0A8W4FDT9 A0A8W4FKM9 A5JT15 A7LJT9 E0A8P1 E2I6L6 E9KYT3 F1REZ2 F1RIA4 F1RIN7 F1RJE3 F1RM45 F1RPW2 F1RQR2 F1RV24 F1RV73 F1RVH7 F1RWV2 F1RX36 F1S0L5 F1S4I1 F1S596 F1S708 F1SAM3 F1SCE4 F1SCU3 F1SGP8 F1SJZ1 F1SM14 F1SPP8 F1SPU1 F1SQX4 F1SS24 F1SSN5 F1STR4 F6PZL5 I3LBK9 I3LGB2 I3LIW9 I3LLG6 I3LU40 I3LUI4 I3LUV5 I3LVB2 K7GQ93 K7GRE3 O02668 O77633 P14287 P45561 P79307 Q0Z8R0 Q28989 Q8MJ76 Q9GLG4	A4 AD1 ADAM10 AFP AHSG ALB AMBN AMEL ANO8 APLP2 APOA1 APOA2 APOA5 APOB APOE APP ATGL BMP15 BMP4 BPIFB2 C3 C4A CCN1 CDH2 CHGB CHRDL1 CKAP4 CSF1 CST3 DMP1 DNAJC3 F5 FAM20A FAM20C FGA FGF23 FGG FN1 FSTL1 FUCA2 GAS6 GOLM1 GPC3 HRC HSP90B1 IGFBP1 IGFBP3 IGFBP4 IGFBP5 IGFBP7 IL-6 IL6 ITIH2 KNG1 KTN1 LGALS1 LOC100156062 LOC100738836 LOC106510284 LTBP1 MATN3 MBTPS1 MEGF6 MELTF MEN1 MEPE MGAT4A MIA3 MXRA8 NOTUM NUCB1 OPN P4HB PCSK9 PDIA6 PNPLA2 PRKCSH PROC PRSS23 QSOX1 RCN1 SCG2 SCG3 SDC2 SERPINA1 SERPINC1 SERPIND1 SPARCL1 SPP1 SPP2 STC2 TF TIMP1 TMEM132A TNC TNN UABP-2 VCAN VGF VWA1 WFS1 bmp4	Sus scrofa (pig)
Regulation of IGF Activity by IGFBP	Adipose triglyceride lipase Albumin Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase A Alpha-2-HS-glycoprotein Alpha-L-fucosidase Alpha-fetoprotein Ameloblastin Amelogenin Amyloid beta like protein 2 Amyloid-beta A4 protein Amyloid-beta precursor protein Anoctamin Antithrombin-III Apolipoprotein A-I Apolipoprotein A-II Apolipoprotein A-V Apolipoprotein B Apolipoprotein E Apolipoprotein L3 isoform 1 Apolipoprotein L3 isoform X1 BPI fold containing family B member 2 Bone morphogenetic protein 15 Bone morphogenetic protein 4 CCN family member 1 Cadherin-2 Chordin like 1 Coagulation factor V Complement C3 Complement C4A (Rodgers blood group) Cystatin C Cytoskeleton associated protein 4 Dentin matrix acidic phosphoprotein 1 Disintegrin and metalloproteinase domain-containing protein 10 DnaJ homolog subfamily C member 3 Endoplasmin Extracellular serine/threonine protein kinase FAM20C isoform X1 FAM20A golgi associated secretory pathway pseudokinase Fibrinogen alpha chain Fibrinogen gamma chain Fibroblast growth factor 23 Fibronectin Follistatin-related protein 1 Galectin Glucosidase 2 subunit beta Glypican-3 Golgi membrane protein 1 Growth arrest specific 6 Heparin cofactor 2 Histidine rich calcium binding protein Insulin like growth factor binding protein 7 Insulin-like growth factor I Insulin-like growth factor II Insulin-like growth factor II Insulin-like growth factor-binding protein 1 Insulin-like growth factor-binding protein 2 Insulin-like growth factor-binding protein 3 Insulin-like growth factor-binding protein 4 Insulin-like growth factor-binding protein 5 Insulin-like growth factor-binding protein 6 Inter-alpha-trypsin inhibitor heavy chain H2 Interleukin-6 Kinectin 1 Kininogen 1 Latent transforming growth factor beta binding protein 1 MIA SH3 domain ER export factor 3 Macrophage colony-stimulating factor 1 Matrilin 3 Matrix extracellular phosphoglycoprotein Matrix remodeling-associated protein 8 Melanotransferrin Membrane bound transcription factor peptidase, site 1 Menin Metalloproteinase inhibitor 1 Multiple EGF like domains 6 Nucleobindin-1 Osteopontin Pappalysin 1 Pappalysin 2 Proprotein convertase subtilisin/kexin type 9 Protein disulfide-isomerase A6 Protein disulfide-isomerase Reticulocalbin-1 SPARC like 1 Secreted phosphoprotein 24 Secretogranin-1 Secretogranin-2 Secretogranin-3 Serine protease 23 Serotransferrin Serpin family A member 1 Stanniocalcin-2 Sulfhydryl oxidase Syndecan Tenascin C Tenascin N Trans-Golgi network integral membrane protein 2 Transmembrane protein 132A Uteroferrin associated basic protein-2 VGF nerve growth factor inducible Versican core protein Vitamin K-dependent protein C Wolframin ER transmembrane glycoprotein [Wnt protein] O-palmitoleoyl-L-serine hydrolase von Willebrand factor A domain-containing protein 1	A0A286ZQC7 A0A286ZRX5 A0A286ZTE6 A0A286ZU78 A0A286ZWQ1 A0A286ZZH4 A0A287A5V7 A0A287AF70 A0A287AFA5 A0A287AG13 A0A287AKS6 A0A287ALA1 A0A287AXR0 A0A287AYJ5 A0A287B049 A0A287B0E4 A0A287BAY9 A0A287BDE8 A0A287BFZ3 A0A287BHU3 A0A287BJL7 A0A287BP22 A0A287BPE2 A0A288CFV5 A0A480P2S5 A0A480Y2E3 A0A481BCM9 A0A481BLI9 A0A5G2Q797 A0A5G2QCF0 A0A5G2QCL1 A0A5G2QN69 A0A5G2QS80 A0A5G2QUR1 A0A5G2QUU1 A0A5G2QXX3 A0A5G2R599 A0A5G2R6R2 A0A5G2RA54 A0A5G2RDD7 A0A5G2RIA8 A0A5G2RIT7 A0A8W4FB62 A0A8W4FDT9 A0A8W4FKM9 A5JT15 A6ZIC9 A7LJT9 E0A8P1 E2I6L6 E9KYT3 F1REZ2 F1RIA4 F1RIN7 F1RJE3 F1RM45 F1RPW2 F1RQR2 F1RV24 F1RV73 F1RVH7 F1RWV2 F1RX36 F1S0L5 F1S4I1 F1S596 F1S703 F1S708 F1SAM3 F1SCE4 F1SCU3 F1SGP8 F1SJZ1 F1SM14 F1SMI4 F1SPP8 F1SPU1 F1SQX4 F1SS24 F1SSN5 F1STR4 F6PZL5 I3LBK9 I3LGB2 I3LIW9 I3LLG6 I3LU40 I3LUI4 I3LUV5 I3LVB2 K7GQ93 K7GRE3 O02668 O77633 P14287 P16545 P23695 P24853 P45561 P79307 Q0Z8R0 Q28989 Q8MJ76 Q9GLG4	A4 AD1 ADAM10 AFP AHSG ALB AMBN AMEL ANO8 APLP2 APOA1 APOA2 APOA5 APOB APOE APP ATGL BMP15 BMP4 BPIFB2 C3 C4A CCN1 CDH2 CHGB CHRDL1 CKAP4 CSF1 CST3 DMP1 DNAJC3 F5 FAM20A FAM20C FGA FGF23 FGG FN1 FSTL1 FUCA2 GAS6 GOLM1 GPC3 HRC HSP90B1 IGF1 IGF2 IGFBP1 IGFBP2 IGFBP3 IGFBP4 IGFBP5 IGFBP6 IGFBP7 IL-6 IL6 ITIH2 KNG1 KTN1 LGALS1 LOC100156062 LOC100738836 LOC106510284 LTBP1 MATN3 MBTPS1 MEGF6 MELTF MEN1 MEPE MGAT4A MIA3 MXRA8 NOTUM NUCB1 OPN P4HB PAPPA PAPPA2 PCSK9 PDIA6 PNPLA2 PRKCSH PROC PRSS23 QSOX1 RCN1 SCG2 SCG3 SDC2 SERPINA1 SERPINC1 SERPIND1 SPARCL1 SPP1 SPP2 STC2 TF TIMP1 TMEM132A TNC TNN UABP-2 VCAN VGF VWA1 WFS1 bmp4	Sus scrofa (pig)
SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription	CDK9 Cyclin K Cyclin T2 Cyclin-C Cyclin-T1 Cyclin-dependent kinase 8 E2F transcription factor 4 E2F transcription factor 5 Menin Mitogen-activated protein kinase Mitogen-activated protein kinase Mothers against decapentaplegic homolog 3 Mothers against decapentaplegic homolog 4 Mothers against decapentaplegic homolog Mothers against decapentaplegic homolog Polyubiquitin-C RB transcriptional corepressor like 1 RING-type E3 ubiquitin transferase Sp1 transcription factor Transcription factor Ubiquitin B Ubiquitin C Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein WW domain containing transcription regulator 1 furin	A0A286ZQB6 A0A286ZZJ6 A0A286ZZW3 A0A287A3Y0 A0A287AEE7 A0A287ALK4 A0A287AZA7 A0A287B504 A0A287BE69 A0A2C9F3G2 A0A480NH74 A0A5G2RG05 A0A8W4F719 A7U5U2 C9E1C9 F1CK19 F1RMJ1 F1RN38 F1RQR2 F1RXB8 F1S911 F1SAQ3 F1SJP0 P0CG68 P84024 Q9GKQ9	CCNC CCNK CCNT1 CCNT2 CDK8 CDK9 E2F4 E2F5 FURIN MADH3 MADH4 MAPK1 MAPK3 MEN1 RBL1 RNF111 RPS27A SMAD2 SMAD3 SMAD4 SMAD7 SP1 Smad7 TFDP1 UBA52 UBB UBC WWTR1	Sus scrofa (pig)
RNA polymerase II transcribes snRNA genes	Arsenite-resistance protein 2 CDK9 Cyclin K Cyclin T2 Cyclin-T1 Cyclin-dependent kinase 7 DNA-directed RNA polymerase II subunit E DNA-directed RNA polymerase II subunit RPB9 DNA-directed RNA polymerase RBP11-like dimerisation domain-containing protein DNA-directed RNA polymerase subunit beta DNA-directed RNA polymerase subunit DNA-directed RNA polymerase subunit DNA-directed RNA polymerases I, II, and III subunit RPABC3 DNA-directed RNA polymerases I, II, and III subunit RPABC5 Elongation factor for RNA polymerase II 2 Elongation factor for RNA polymerase II 3 General transcription factor IIE subunit 1 Integrator complex subunit 10 Integrator complex subunit 11 Integrator complex subunit 12 Integrator complex subunit 13 Integrator complex subunit 1 Integrator complex subunit 2 Integrator complex subunit 3 Integrator complex subunit 4 Integrator complex subunit 5 Integrator complex subunit 6 Integrator complex subunit 7 Integrator complex subunit 8 Integrator complex subunit 9 Interactor of little elongation complex ELL subunit 1 Interactor of little elongation complex ELL subunit 2 Nuclear cap binding protein subunit 1 Nuclear cap-binding protein subunit 2 Nucleic acid binding protein 2 PCF11 cleavage and polyadenylation factor subunit POU domain protein POU domain protein Phosphorylated adapter RNA export protein RNA polymerase II subunit A C-terminal domain phosphatase SSU72 RNA polymerase II subunit B1 CTD phosphatase RPAP2 homolog RNA polymerase II subunit D Ral transcription factor IIA subunit 1 Regulation of nuclear pre-mRNA domain containing 2 Regulation of nuclear pre-mRNA domain-containing protein Small nuclear RNA activating complex polypeptide 1 Small nuclear RNA activating complex polypeptide 2 Small nuclear RNA activating complex polypeptide 4 Small nuclear RNA activating complex polypeptide 5 Sp1 transcription factor TATA-box binding protein associated factor 11 TATA-box binding protein associated factor 13 TATA-box binding protein associated factor 5 TATA-box binding protein associated factor 9 Transcription elongation factor SPT4 Transcription elongation factor SPT5 Transcription initiation factor IIA subunit 2 Transcription initiation factor IIB Transcription initiation factor IIE subunit beta Transcription initiation factor IIF subunit alpha Transcription initiation factor TFIID subunit 6 Transcription initiation factor TFIID subunit 8 snRNA-activating protein complex subunit 3	A0A286ZQB6 A0A286ZSR2 A0A286ZWK5 A0A286ZZJ6 A0A287A0W8 A0A287ADR4 A0A287AFL9 A0A287AL22 A0A287B2D4 A0A287B756 A0A287B947 A0A287BAH6 A0A287BD12 A0A287BF49 A0A287BH65 A0A287BKD1 A0A287BRS7 A0A287BT48 A0A480JTG5 A0A480PU90 A0A480VIE8 A0A5G2QD06 A0A5G2QFS1 A0A5G2QPV0 A0A5G2QRV8 A0A5G2QTZ9 A0A5G2QYQ2 A0A5G2R4N4 A0A5G2R6C5 A0A5G2R6U9 A0A5G2RF15 A0A8W4F719 A0A8W4F9W9 A0A8W4FEY2 A0A8W4FNR9 C9E1C9 F1RJC9 F1RX65 F1RY55 F1RZ14 F1S074 F1S221 F1S845 F1SA68 F1SAQ3 F1SBT5 F1SE01 F1SFW4 F1SI81 F1SLZ8 F1STU9 F1STY6 F2Z5Q4 F2Z5Q9 I3LGP4 I3LI05 I3LJR4 I3LJV3 I3LMH3 I3LRU6 I3LT26 I3LTH2 P60899	CCNK CCNT1 CCNT2 CDK7 CDK9 ELL2 ELL3 GTF2A1 GTF2A2 GTF2B GTF2E1 GTF2E2 GTF2F1 ICE1 ICE2 INTS1 INTS10 INTS11 INTS12 INTS13 INTS2 INTS3 INTS4 INTS5 INTS6 INTS7 INTS8 INTS9 NABP2 NCBP1 NCBP2 PCF11 PHAX POLR2A POLR2B POLR2D POLR2E POLR2G POLR2H POLR2I POLR2J POLR2L POU2F1 POU2F2 RPAP2 RPRD1A RPRD2 SNAPC1 SNAPC2 SNAPC3 SNAPC4 SNAPC5 SP1 SRRT SSU72 SUPT4H1 SUPT5H TAF11 TAF13 TAF5 TAF6 TAF8 TAF9	Sus scrofa (pig)
EGFR downregulation	Amphiregulin Betacellulin Cell division control protein 42 homolog E3 ubiquitin-protein ligase CBL Endophilin-A2 Epidermal growth factor receptor pathway substrate 15 like 1 Epidermal growth factor receptor pathway substrate 15 Epiregulin Epsin 1 Growth factor receptor bound protein 2 Hepatocyte growth factor-regulated tyrosine kinase substrate Polyubiquitin-C Pro-epidermal growth factor Proheparin-binding EGF-like growth factor Protein sprouty homolog 1 Receptor protein-tyrosine kinase Rho guanine nucleotide exchange factor 7 SH3 domain containing GRB2 like 3, endophilin A3 SH3 domain containing kinase binding protein 1 Signal transducing adaptor molecule 2 Signal transducing adaptor molecule Transforming growth factor alpha Tyrosine-protein phosphatase non-receptor type Ubiquitin B Ubiquitin C Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein protein-tyrosine-phosphatase protein-tyrosine-phosphatase	A0A286ZPM4 A0A286ZQE1 A0A286ZY48 A0A287A000 A0A287A231 A0A287A519 A0A287A6I2 A0A287AR65 A0A287AZA7 A0A287AZM9 A0A287B5N2 A0A287BKD5 A0A2C9F3G2 A0A5G2Q9Y0 A0A5G2QBP1 A0A5G2QFX7 A0A5G2RE13 A7U5U2 B6E241 F1RRA2 F1S7L8 F1S911 F1SHW8 F1SLD3 I3LPZ5 P0CG68 Q007T2 Q01580 Q9BDH4	AREG ARHGEF7 BTC CBL CDC42 DTR EGF EGFR EPN1 EPS15 EPS15L1 EREG GRB2 HBEGF HEGFL HGS PTPN12 PTPN3 PTPRK RPS27A SH3GL1 SH3GL3 SH3KBP1 SPRY1 STAM STAM2 TGFA UBA52 UBB UBC	Sus scrofa (pig)
TNFs bind their physiological receptors	B-cell activating factor CD27 CD70 molecule EDAR associated death domain Ectodysplasin A receptor Ectodysplasin A Lymphotoxin-alpha TNF receptor superfamily member 13B TNF receptor superfamily member 17 TNF receptor superfamily member 18 TNF receptor superfamily member 1B TNF receptor superfamily member 25 TNF receptor superfamily member 4 TNF receptor superfamily member 9 TNF superfamily member 11 TNF superfamily member 13 TNF superfamily member 15 TNF superfamily member 18 TNF superfamily member 4 TNF superfamily member 9 Tumor necrosis factor receptor superfamily member 11B Tumor necrosis factor receptor superfamily member 1A	A0A286ZPI2 A0A286ZQA0 A0A286ZVH7 A0A287A0L0 A0A287A7B3 A0A5K1VKG5 A0A5S6H780 A0A8W4FAC7 A0A8W4FCJ9 A0A8W4FMJ5 A0MTC9 F1RJX1 F1S746 F1SBT1 F1SU31 I3LDN7 I3LL00 I3LP81 K7GPY3 L7QHB1 P26445 Q4QTJ8	CD27 CD70 EDA EDAR EDARADD LTA TNFB TNFRSF11B TNFRSF13B TNFRSF17 TNFRSF18 TNFRSF1A TNFRSF1B TNFRSF25 TNFRSF4 TNFRSF9 TNFSF1 TNFSF11 TNFSF13 TNFSF13B TNFSF15 TNFSF18 TNFSF4 TNFSF9	Sus scrofa (pig)
Retinoid metabolism and transport	Agrin Aldo-keto reductase family 1 member C1 Apolipoprotein A-I Apolipoprotein A-II Apolipoprotein A-IV Apolipoprotein B Apolipoprotein C-II Apolipoprotein C-III Apolipoprotein E Apolipoprotein M Beta-carotene oxygenase 1 Carotenoid-cleaving dioxygenase, mitochondrial Colipase Glypican 2 Glypican 4 Glypican 5 Glypican-1 Glypican-3 Glypican-6 LDL receptor related protein 10 LDL receptor related protein 12 LDL receptor related protein 8 Lecithin retinol acyltransferase Lipoprotein lipase Phospholipase B1, membrane-associated Putative aldo-keto reductase family 1 member C2 Retinol binding protein 1 Retinol binding protein 2 Retinol dehydrogenase 11 Retinol-binding protein Syndecan-4 Syndecan Syndecan Syndecan Transthyretin Transthyretin Triacylglycerol lipase	A0A286ZPB0 A0A286ZQC7 A0A286ZS39 A0A286ZXB4 A0A287AG13 A0A287AJ15 A0A287ATH4 A0A287AW22 A0A287B0A0 A0A287B286 A0A287BCU5 A0A287BM29 A0A480K0L3 A0A480KVF0 A0A480YJR0 A0A481BCM9 A0A5G2QEH1 A0A5G2QIE9 A0A5G2QTV7 A0A5G2RI58 A0A5G2RJR8 E7CXS0 F1RM45 F1RNM8 F1RTE1 F1RYR6 F1S0L5 F1SA24 F1SC80 F6PSJ3 K7GNF5 K7GQ93 P02703 P27917 P50390 Q2LE37 Q8HZJ6	AGRN AKR1C1 AKR1C2 APOA1 APOA2 APOA4 APOB APOC2 APOC3 APOE APOM ApoER2 BCO1 BCO2 CLPS GPC1 GPC2 GPC3 GPC4 GPC5 GPC6 LPL LRAT LRP10 LRP12 LRP8 PLB1 PNLIP RBP1 RBP2 RBP4 RDH11 SDC1 SDC2 SDC3 SDC4 TTR	Sus scrofa (pig)
Regulation of insulin secretion	ATP binding cassette subfamily C member 8 Calcium voltage-gated channel auxiliary subunit alpha2delta 2 Rap guanine nucleotide exchange factor 3 Rap guanine nucleotide exchange factor 4 Solute carrier family 2, facilitated glucose transporter member 1 Solute carrier family 2, facilitated glucose transporter member 2 Solute carrier family 2, facilitated glucose transporter member 2 Voltage-dependent L-type calcium channel subunit alpha Voltage-dependent L-type calcium channel subunit beta-2 Voltage-dependent L-type calcium channel subunit beta-3 Voltage-dependent R-type calcium channel subunit alpha	A0A286ZP06 A0A286ZP52 A0A5G2QE81 A0A8W4FF87 A0A8W4FPK7 F1S067 F1S675 F1S9A6 I3L7Z0 O62786 P20303	ABCC8 CACNA1D CACNA1E CACNA2D2 CACNB2 CACNB3 GLUT1 GLUT2 RAPGEF3 RAPGEF4 SLC2A1 SLC2A2	Sus scrofa (pig)	G58161NS
A tetrasaccharide linker sequence is required for GAG synthesis	Agrin Beta-1,4-galactosyltransferase Biglycan Brevican core protein Chondroitin sulfate proteoglycan 4 Chondroitin sulfate proteoglycan 5 Decorin Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase Glypican 2 Glypican 4 Glypican 5 Glypican-1 Glypican-3 Glypican-6 Hexosyltransferase Neurocan Syndecan-4 Syndecan Syndecan Syndecan Versican core protein Xylosyltransferase 1 Xylosyltransferase 2	A0A286ZNW5 A0A286ZS39 A0A286ZTI9 A0A287AHN9 A0A287AIY6 A0A287AJ15 A0A287ATH4 A0A287B286 A0A480K0L3 A0A5G2RB02 A0A5K1UKC5 A0A8W4FKJ8 F1REZ2 F1RLT2 F1RNM8 F1RT78 F1RTE1 F1S0L5 F1SJ86 I3LK23 I3LR31 I3LU42 K7GNF5 K7GQ93 Q8HZJ6	AGRN B3GALT6 B3GAT1 B3GAT2 B3GAT3 B4GALT7 BCAN BGN CSPG4 CSPG5 DCN GPC1 GPC2 GPC3 GPC4 GPC5 GPC6 NCAN SDC1 SDC2 SDC3 SDC4 VCAN XYLT1 XYLT2	Sus scrofa (pig)

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