Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1

Summary
Species
Homo sapiens
Reactome
PubChem
Click on a node on the pathway to see its details. Glycoproteins are marked with a glycoprotein icon in their name.
E2F1 geneE2F1HDAC1:RBL2:E2F4,E2F5:TFDP1,TFDP2; HDAC1:RBL1:E2F4:TFDP1,TFDP2HDAC1:RBL2:E2F4,E2F5:TFDP1,TFDP2; HDAC1:RBL1:E2F4:TFDP1,TFDP2:CCNA2 geneCCNA2 geneCCNA2CDK1 geneHDAC1:RBL2:E2F4,E2F5:TFDP1,TFDP2; HDAC1:RBL1:E2F4:TFDP1,TFDP2:CDK1 geneCDK1HDAC1:RBL2:E2F4,E2F5:TFDP1,TFDP2; HDAC1:RBL1:E2F4:TFDP1,TFDP2:E2F1 geneHDAC1:RBL2:E2F4,E2F5:TFDP1,TFDP2; HDAC1:RBL1:E2F4:TFDP1,TFDP2:MYBL2 geneMYBL2 geneBMYB
ProteinProtein familyDNARNAComplexChemical/MoleculePhenotype/StimulusNucleusMitochondriaEndosomeGolgi apparatusLysosomeMembraneUp-regulatesDown-regulatesPhysical interactionUnknownDirectIndirectBindingHighlight
Displaying all 8 entries
UniProt ID Protein Name Gene Symbol Pathway Viewer
P10244 Myb-related protein B
  • BMYB
  • MYBL2
view
Q01094 Transcription factor E2F1
  • E2F1
  • RBBP3
view
Q08999 Retinoblastoma-like protein 2
  • RB2
  • RBL2
view
Q09028 Histone-binding protein RBBP4
  • RBAP48
  • RBBP4
view
Q13547 Histone deacetylase 1
  • HDAC1
  • RPD3L1
view
Q16254 Transcription factor E2F4
  • E2F4
view
Q6MZP7 Protein lin-54 homolog
  • CXCDC1
  • KIAA2037
  • LIN54
view
Q96GY3 Protein lin-37 homolog
  • LIN37
view
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International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: April 7, 2025