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MIRAGE
Heme biosynthesis

Summary
Species
Homo sapiens
Reactome
PubChem
Click on a node on the pathway to see its details. Glycoproteins are marked with a glycoprotein icon in their name.
ferrohemehemeH2OPiATPH+ADPGlydALAH+CO2SUCC-CoACoAdALA8x(ALAD:Zn2+)8xALAD:Pb2+:Zn2+Pb2+Zn2+PBGNH4+HMBLURO3URO1COPRO3CO2COPRO1COPRO3H+H2OPPGEN9O2CO2PRIN9H2O2PRIN9heme bFe2+hemeALBALB:hemePPiH2OFPPheme Ohydrogen acceptorhydrogen donorheme A
ProteinProtein familyDNARNAComplexChemical/MoleculePhenotype/StimulusNucleusMitochondriaEndosomeGolgi apparatusLysosomeMembraneUp-regulatesDown-regulatesPhysical interactionUnknownDirectIndirectBindingHighlight
SPV: a JavaScript Signaling Pathway Visualizer, Bioinformatics, 2018
If you want to check the location of a particular molecule, you can do so by clicking on the "Switching Highlight" button on the page you have navigated to by clicking on "view".
a simple tooltip
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International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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GlyCosmos Portal v4.2.1

Last updated: April 7, 2025