NRAGE signals death through JNK

Summary
Species
Homo sapiens
Reactome
PubChem
Click on a node on the pathway to see its details. Glycoproteins are marked with a glycoprotein icon in their name.
mature NGF homodimer:p75NTRNGF:p75NTR:NRAGENRAGENGF ligand:p75NTR:NRAGE:CHE1AATFJNK1ADPp-T,Y-JNK1ATPGTPRAC1:GTPGDPRAC1:GDPBIMp-S91-BADBADBCL2L11p-T,Y-JNK1
ProteinProtein familyDNARNAComplexChemical/MoleculePhenotype/StimulusNucleusMitochondriaEndosomeGolgi apparatusLysosomeMembraneUp-regulatesDown-regulatesPhysical interactionUnknownDirectIndirectBindingHighlight
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International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: April 7, 2025