TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest

Summary
Species
Homo sapiens
Reactome
PubChem
Click on a node on the pathway to see its details. Glycoproteins are marked with a glycoprotein icon in their name.
ARID3A Genep-S15,S20-TP53 Tetramer:ARID3A Genep-S15,S20-TP53 TetramerDRXE2F7 Genep-S15,S20-TP53 Tetramer:E2F7 GeneE2F72xE2F7E2F8E2F7:E2F82xE2F8E2F7,E2F8 dimersE2F7,E2F8 dimers:E2F1 GeneE2F1 geneE2F1PCBP4 Genep-S15,S20-TP53 Tetramer:PCBP4 GenePCBP4p21 genep-S15,S20-TP53 Tetramer:ZNF385A:CDKN1A Genep-S15,S20-TP53 Tetramer:ZNF385Ap21 mRNAPCBP4:CDKN1A mRNAp21p21,p27Cyclin E:CDK2:p21,p27CCNE:CDK2CCNA:CDK2Cyclin A:Cdk2:p21/p27 complex
ProteinProtein familyDNARNAComplexChemical/MoleculePhenotype/StimulusNucleusMitochondriaEndosomeGolgi apparatusLysosomeMembraneUp-regulatesDown-regulatesPhysical interactionUnknownDirectIndirectBindingHighlight
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International Collaboration

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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: April 7, 2025