GPER1 signaling

Summary
Species
Homo sapiens
Reactome
PubChem
Click on a node on the pathway to see its details. Glycoproteins are marked with a glycoprotein icon in their name.
cAMPPKA tetramer:4xcAMPPKA tetramerPRKACA,PRKACB,PRKACGcAMP:PKA regulatory subunitPKA catalytic subunitsGPER1:Heterotrimeric G-protein Gs (inactive)GPER1:Heterotrimeric G-protein Gs:ESTGESTGGDPGTPGPER1:Heterotrimeric G-protein Gs (active):ESTGGPER1:ESTGGs:GTPG-protein beta-gamma complexATPpY-SHC1ADPSHC1integrin alpha5beta1:Fibronectin matrix:pY-SHC1Integrin alpha5beta1:Fibronectin matrixAdenylate cyclase (Mg2+ cofactor)Gs-activated adenylate cyclasePPi
ProteinProtein familyDNARNAComplexChemical/MoleculePhenotype/StimulusNucleusMitochondriaEndosomeGolgi apparatusLysosomeMembraneUp-regulatesDown-regulatesPhysical interactionUnknownDirectIndirectBindingHighlight
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International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: April 7, 2025