idiopathic pulmonary fibrosis

Summary
Synonym
  • FIBROCYSTIC PULMONARY DYSPLASIA
  • IDIOPATHIC PULMONARY FIBROSIS, FAMILIAL
  • cryptogenic fibrosing alveolitis
Definition
A pulmonary fibrosis that is characterized by scarring of the lung.
Super Class
pulmonary fibrosis
Disease Ontology
DOID:0050156
Mondo Disease Ontology
MeSH
UMLS
NCI Thesaurus
OMIM
GARD
MGI genotype (from TogoID)
Related Genes
Displaying entries 1 - 10 of 27 in total
Gene ID Gene Symbol Description Source
142 PARP1 poly(ADP-ribose) polymerase 1
207 AKT1 AKT serine/threonine kinase 1
335 APOA1 apolipoprotein A1
780 DDR1 discoidin domain receptor tyrosine kinase 1
2033 EP300 E1A binding protein p300
2152 F3 coagulation factor III, tissue factor
2263 FGFR2 fibroblast growth factor receptor 2
2355 FOSL2 FOS like 2, AP-1 transcription factor subunit
3123 HLA-DRB1 major histocompatibility complex, class II, DR beta 1
3559 IL2RA interleukin 2 receptor subunit alpha
Displaying entries 1 - 10 of 20 in total
Gene ID Gene Symbol Description Source
11651 Akt1 thymoma viral proto-oncogene 1
12305 Ddr1 discoidin domain receptor family, member 1
14066 F3 coagulation factor III
14183 Fgfr2 fibroblast growth factor receptor 2
14284 Fosl2 fos-like antigen 2
14969 H2-Eb1 histocompatibility 2, class II antigen E beta
16184 Il2ra interleukin 2 receptor, alpha chain
17082 Il1rl1 interleukin 1 receptor-like 1
17126 Smad2 SMAD family member 2
17829 Muc1 mucin 1, transmembrane
Displaying all 10 entries
Gene ID Gene Symbol Description Source
24185 Akt1 AKT serine/threonine kinase 1
24773 Sftpa1 surfactant protein A1
24835 Tnf tumor necrosis factor
25022 Fgfr2 fibroblast growth factor receptor 2
25054 Ntrk2 neurotrophic receptor tyrosine kinase 2
25556 Il1rl1 interleukin 1 receptor-like 1
25591 Parp1 poly (ADP-ribose) polymerase 1
25704 Il2ra interleukin 2 receptor subunit alpha
29436 Tfpi tissue factor pathway inhibitor
29527 Ptgs2 prostaglandin-endoperoxide synthase 2
Displaying all 4 entries
Gene ID Gene Symbol Description Source
31722 fs(1)h female sterile (1) homeotic
39564 btl breathless
42160 htl heartless
3355109 Parp1 Poly-(ADP-ribose) polymerase 1
Displaying all 2 entries
Gene ID Gene Symbol Description Source
352940 fgfr2 fibroblast growth factor receptor 2
560788 parp1 poly (ADP-ribose) polymerase 1
Displaying 1 entry
Gene ID Gene Symbol Description Source Organism
399170 akt1.S AKT serine/threonine kinase 1 S homeolog Xenopus laevis (African clawed frog)
Displaying all 4 entries
Gene ID Gene Symbol Description Source
178748 zmp-3 Matrix metalloproteinase-C
180622 ddr-2 Discoidin domain-containing receptor tyrosine kinase B
180836 W01C8.5 DM13 domain-containing protein
266823 parp-1 Poly [ADP-ribose] polymerase;Poly [ADP-ribose] polymerase 1
The Human Phenotype Ontology
Displaying entries 11 - 17 of 17 in total
HPO ID HPO Term
HP:0002875 Exertional dyspnea
HP:0010702 Increased circulating antibody level
HP:0002094 Dyspnea
HP:0000006 Autosomal dominant inheritance
HP:0001394 Cirrhosis
HP:0006519 Alveolar cell carcinoma
HP:0002092 Pulmonary arterial hypertension
Displaying all 3 entries
Gene ID Gene Symbol Description
6440 SFTPC surfactant protein C
653509 SFTPA1 surfactant protein A1
729238 SFTPA2 surfactant protein A2

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Last updated: December 9, 2024