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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
open-angle glaucoma
Summary
- Synonym
-
- Wide-angle glaucoma
- glaucoma simplex
- open angle glaucoma
- pigmentary glaucoma
- Definition
- A glaucoma characterized by optic nerve damage resulting in progressive loss of visual field and increased pressure in the eye due to trabecular blockage.
- Super Class
- glaucoma
External Links
- Disease Ontology
- DOID:1067
- Mondo Disease Ontology
- MeSH
- UMLS
- NCI Thesaurus
- OMIM
- MGI genotype (from TogoID)
Related Genes
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 28 | ABO | ABO, alpha 1-3-N-acetylgalactosaminyltransferase and alpha 1-3-galactosyltransferase | |
| 231 | AKR1B1 | aldo-keto reductase family 1 member B | |
| 501 | ALDH7A1 | aldehyde dehydrogenase 7 family member A1 | |
| 952 | CD38 | CD38 molecule | |
| 1545 | CYP1B1 | cytochrome P450 family 1 subfamily B member 1 | |
| 1636 | ACE | angiotensin I converting enzyme | |
| 2762 | GMDS | GDP-mannose 4,6-dehydratase | |
| 5373 | PMM2 | phosphomannomutase 2 | |
| 5730 | PTGDS | prostaglandin D2 synthase | |
| 5743 | PTGS2 | prostaglandin-endoperoxide synthase 2 |
Related Glycoprotein
| UniProt ID | Protein Name | Source |
|---|---|---|
| Q16678 | Cytochrome P450 1B1 | |
| Q16760 | Diacylglycerol kinase delta | |
| Q9P212 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase epsilon-1 |
- The Human Phenotype Ontology
| HPO ID | HPO Term |
|---|---|
| HP:0007906 | Ocular hypertension |
| HP:0000593 | Abnormal anterior chamber morphology |
| HP:0012511 | Temporal optic disc pallor |
| HP:0000525 | Abnormality iris morphology |
| HP:0011003 | High myopia |
| HP:0012796 | Increased cup-to-disc ratio |
| HP:0001138 | Optic neuropathy |
| HP:0000505 | Visual impairment |
| HP:0007854 | Glaucomatous visual field defect |
| HP:0012108 | Open angle glaucoma |
