primary open angle glaucoma

Summary
Synonym
  • chronic simple glaucoma
Definition
An open-angle glaucoma that is characterized by the absence of any apparent obstruction of aqueous outflow through the trabecular meshwork with gonioscopy, but often with elevated intraocular pressure.
Super Class
open-angle glaucoma
Disease Ontology
DOID:1070
Mondo Disease Ontology
MeSH
UMLS
NCI Thesaurus
OMIM
MGI genotype (from TogoID)
Related Genes
Displaying entries 1 - 10 of 27 in total
Gene ID Gene Symbol Description Source
90 ACVR1 activin A receptor type 1
154 ADRB2 adrenoceptor beta 2
348 APOE apolipoprotein E
627 BDNF brain derived neurotrophic factor
1293 COL6A3 collagen type VI alpha 3 chain
1545 CYP1B1 cytochrome P450 family 1 subfamily B member 1
1906 EDN1 endothelin 1
2006 ELN elastin
2752 GLUL glutamate-ammonia ligase
3913 LAMB2 laminin subunit beta 2
Displaying entries 11 - 20 of 20 in total
Gene ID Gene Symbol Description Source
18127 Nos3 nitric oxide synthase 3, endothelial cell
18294 Ogg1 8-oxoguanine DNA-glycosylase 1
18979 Pon1 paraoxonase 1
20656 Sod2 superoxide dismutase 2, mitochondrial
21825 Thbs1 thrombospondin 1
21898 Tlr4 toll-like receptor 4
21926 Tnf tumor necrosis factor
22059 Trp53 transformation related protein 53
60596 Gucy1a1 guanylate cyclase 1, soluble, alpha 1
83995 Mmp1a matrix metallopeptidase 1a (interstitial collagenase)
Displaying entries 11 - 12 of 12 in total
Gene ID Gene Symbol Description Source
81528 Ogg1 8-oxoguanine DNA glycosylase
84024 Pon1 paraoxonase 1
Displaying all 3 entries
Gene ID Gene Symbol Description Source
31806 Ogg1 8-oxoguanine DNA glycosylase
41549 Octbeta2R Octopamine beta2 receptor
43222 Tl Toll
Displaying 1 entry
Gene ID Gene Symbol Description Source
447803 pon1 paraoxonase 1
Displaying 1 entry
Gene ID Gene Symbol Description Source Organism
448598 pon2 paraoxonase 2 Xenopus tropicalis (tropical clawed frog)
Displaying all 7 entries
Gene ID Gene Symbol Description Source
171999 poml-2 Arylesterase
174044 sma-6 Serine/threonine-protein kinase receptor sma-6
176829 daf-1 Cell surface receptor daf-1
177292 lam-1 Laminin subunit beta-1
178748 zmp-3 Matrix metalloproteinase-C
182256 R193.2 VWFA domain-containing protein
187297 poml-1 PON (paraoxonase) and MEC-6 Like
Displaying 1 entry
Gene ID Gene Symbol Description Source
854942 OGG1 8-oxoguanine glycosylase OGG1

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Last updated: December 9, 2024