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granulomatosis with polyangiitis
Summary
- Synonym
-
- Necrotizing respiratory granulomatosis
- Wegener granulomatosis, formerly
- Definition
- An autoimmune disease that is characterized by necrotizing granulomatous inflammation of the upper and lower respiratory tract, glomerulonephritis, vasculitis, and the presence of antineutrophil cytoplasmatic autoantibodies (ANCAs) in patient sera, and is located_in lung, located_in kidney, located_in skin resulting from an autoimmune attack by antineutrophil cytoplasmic antibodies against small and medium-size blood vessels.
- Super Class
- autoimmune disease of blood kidney disease lung disease skin disease
External Links
- Disease Ontology
- DOID:12132
- Mondo Disease Ontology
- MeSH
- UMLS
- NCI Thesaurus
- OMIM
- GARD
Related Genes
Related Glycoprotein
| UniProt ID | Protein Name | Source |
|---|---|---|
| O15327 | Inositol polyphosphate 4-phosphatase type II | |
| O75015 | Low affinity immunoglobulin gamma Fc region receptor III-B | |
| P06280 | Alpha-galactosidase A | |
| P12821 | Angiotensin-converting enzyme | |
| P16109 | P-selectin | |
| P16442 | Histo-blood group ABO system transferase | |
| P19320 | Vascular cell adhesion protein 1 | |
| P19835 | Bile salt-activated lipase | |
| P21589 | 5'-nucleotidase | |
| P36222 | Chitinase-3-like protein 1 |
