Submissions
GlyTouCan
Glycan Structure Repository
GlyComb
Glycoconjugate Repository
GlycoPOST
Glycomics MS raw data Repository
UniCarb-DR
Glycomics MS Repository for glycan annotations from GlycoWorkbench
All Resources
Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Lewy body dementia
Summary
- Synonym
-
- Dementia with Lewy bodies
- Diffuse Lewy body disease
- Lewy body disease
- Senile dementia of the Lewy body type
- Definition
- A dementia that is characterized by the development of abnormal proteinaceous (alpha-synuclein) cytoplasmic inclusions, called Lewy bodies, throughout the brain that results in progressive decline in mental abilities.
- Super Class
- dementia
Related Genes
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 43 | ACHE | acetylcholinesterase (Yt blood group) | |
| 308 | ANXA5 | annexin A5 | |
| 427 | ASAH1 | N-acylsphingosine amidohydrolase 1 | |
| 1116 | CHI3L1 | chitinase 3 like 1 | |
| 1312 | COMT | catechol-O-methyltransferase | |
| 1555 | CYP2B6 | cytochrome P450 family 2 subfamily B member 6 | |
| 1636 | ACE | angiotensin I converting enzyme | |
| 1738 | DLD | dihydrolipoamide dehydrogenase | |
| 2026 | ENO2 | enolase 2 | |
| 2053 | EPHX2 | epoxide hydrolase 2 |
Related Glycoprotein
| UniProt ID | Protein Name | Source |
|---|---|---|
| P19320 | Vascular cell adhesion protein 1 | |
| P20916 | Myelin-associated glycoprotein | |
| P21964 | Catechol O-methyltransferase | |
| P22303 | Acetylcholinesterase | |
| P29218 | Inositol monophosphatase 1 | |
| P34913 | Bifunctional epoxide hydrolase 2 | |
| P35354 | Prostaglandin G/H synthase 2 | |
| P36222 | Chitinase-3-like protein 1 | |
| P48740 | Mannan-binding lectin serine protease 1 | |
| Q13510 | Acid ceramidase |
- The Human Phenotype Ontology
| HPO ID | HPO Term |
|---|---|
| HP:0001300 | Parkinsonism |
| HP:0000726 | Dementia |
| HP:0007159 | Fluctuations in consciousness |
| HP:0000006 | Autosomal dominant inheritance |
| HP:0002367 | Visual hallucination |
| HP:0100315 | Lewy bodies |
| HP:0000746 | Delusion |
