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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
chronic closed-angle glaucoma
Summary
- Synonym
-
- Anatomical narrow angle glaucoma
- chronic angle-closure glaucoma
- chronic narrow angle glaucoma
- Definition
- A primary angle-closure glaucoma characterized by chronic and progressive narrowing of the anterior chamber angle by an intrinsic defect such that aqueous outflow is blocked and the intraocular pressure becomes inappropriately elevated leading to optic nerve damage and visual field loss. Chronic closed-angle glaucoma has_symptom progressive loss of peripheral vision, decreased vision, and occasionally headaches. Chronic closed-angle glaucoma can be caused by anatomically narrow angle, defects in the trabecular meshwork, and iris abnormalities. Primary angle-closure glaucoma has a strong genetic component.
- Super Class
- primary angle-closure glaucoma
External Links
- Disease Ontology
- DOID:14445
- UMLS
Related Genes
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 847 | CAT | catalase | |
| 1103 | CHAT | choline O-acetyltransferase | |
| 1109 | AKR1C4 | aldo-keto reductase family 1 member C4 | |
| 1545 | CYP1B1 | cytochrome P450 family 1 subfamily B member 1 | |
| 1555 | CYP2B6 | cytochrome P450 family 2 subfamily B member 6 | |
| 1634 | DCN | decorin | |
| 4907 | NT5E | 5'-nucleotidase ecto | |
| 4968 | OGG1 | 8-oxoguanine DNA glycosylase | |
| 8818 | DPM2 | dolichyl-phosphate mannosyltransferase subunit 2, regulatory |
Related Glycoprotein
| UniProt ID | Protein Name | Source |
|---|---|---|
| P04040 | Catalase | |
| P07585 | Decorin | |
| P21589 | 5'-nucleotidase | |
| P28329 | Choline O-acetyltransferase | |
| Q16678 | Cytochrome P450 1B1 |
