major depressive disorder

Summary
Synonym
  • clinical depression
  • major depression
  • recurrent major depression
  • single major depressive episode
  • unipolar depression
Definition
A depressive disorder that is characterized by at least two weeks of loss of interest or pleasure in normally enjoyable activities or depressed mood along with additional cognitive or somatic impairments such as appetite or weight changes, sleep difficulties, psychomotor agitation or retardation, fatigue or loss of energy, diminished ability to think or concentrate, feelings of worthlessness or excessive guilt, and suicidality.
Super Class
depressive disorder
External Links
Disease Ontology
DOID:1470
Mondo Disease Ontology
UMLS
NCI Thesaurus
OMIM
MGI genotype (from TogoID)
WikiPathways (from TogoID)
Related Genes
Displaying entries 111 - 120 of 217 in total
Gene ID Gene Symbol Description Source
5321 PLA2G4A phospholipase A2 group IVA
5332 PLCB4 phospholipase C beta 4
5335 PLCG1 phospholipase C gamma 1
5507 PPP1R3C protein phosphatase 1 regulatory subunit 3C
5538 PPT1 palmitoyl-protein thioesterase 1
5621 PRNP prion protein (Kanno blood group)
5660 PSAP prosaposin
5728 PTEN phosphatase and tensin homolog
5730 PTGDS prostaglandin D2 synthase
5742 PTGS1 prostaglandin-endoperoxide synthase 1
Displaying 1 entry
Gene ID Gene Symbol Description Source
15558 Htr2a 5-hydroxytryptamine (serotonin) receptor 2A
Displaying 1 entry
Gene ID Gene Symbol Description Source
29595 Htr2a 5-hydroxytryptamine receptor 2A

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Last updated: August 19, 2024