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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
major depressive disorder
Summary
- Synonym
-
- clinical depression
- major depression
- recurrent major depression
- single major depressive episode
- unipolar depression
- Definition
- A depressive disorder that is characterized by at least two weeks of loss of interest or pleasure in normally enjoyable activities or depressed mood along with additional cognitive or somatic impairments such as appetite or weight changes, sleep difficulties, psychomotor agitation or retardation, fatigue or loss of energy, diminished ability to think or concentrate, feelings of worthlessness or excessive guilt, and suicidality.
- Super Class
- depressive disorder
External Links
- Disease Ontology
- DOID:1470
- Mondo Disease Ontology
- UMLS
- NCI Thesaurus
- OMIM
- MGI genotype (from TogoID)
- WikiPathways (from TogoID)
Related Genes
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 6609 | SMPD1 | sphingomyelin phosphodiesterase 1 | |
| 6646 | SOAT1 | sterol O-acyltransferase 1 | |
| 6715 | SRD5A1 | steroid 5 alpha-reductase 1 | |
| 6783 | SULT1E1 | sulfotransferase family 1E member 1 | |
| 7357 | UGCG | UDP-glucose ceramide glucosyltransferase | |
| 7412 | VCAM1 | vascular cell adhesion molecule 1 | |
| 7903 | ST8SIA4 | ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4 | |
| 7957 | EPM2A | EPM2A glucan phosphatase, laforin | |
| 7991 | TUSC3 | tumor suppressor candidate 3 | |
| 8398 | PLA2G6 | phospholipase A2 group VI |
Related Glycoprotein
| UniProt ID | Protein Name | Source |
|---|---|---|
| Q9H2K2 | Poly [ADP-ribose] polymerase tankyrase-2 | |
| Q9NQ66 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 | |
| Q9NR19 | Acetyl-coenzyme A synthetase, cytoplasmic | |
| Q9NR45 | Sialic acid synthase | |
| Q9NRA2 | Sialin | |
| Q9NYP7 | Very long chain fatty acid elongase 5 | |
| Q9NZ01 | Very-long-chain enoyl-CoA reductase | |
| Q9P035 | Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 3 | |
| Q9P121 | Neurotrimin | |
| Q9P232 | Contactin-3 |
