major depressive disorder

Summary
Synonym
  • clinical depression
  • major depression
  • recurrent major depression
  • single major depressive episode
  • unipolar depression
Definition
A depressive disorder that is characterized by at least two weeks of loss of interest or pleasure in normally enjoyable activities or depressed mood along with additional cognitive or somatic impairments such as appetite or weight changes, sleep difficulties, psychomotor agitation or retardation, fatigue or loss of energy, diminished ability to think or concentrate, feelings of worthlessness or excessive guilt, and suicidality.
Super Class
depressive disorder
External Links
Disease Ontology
DOID:1470
Mondo Disease Ontology
UMLS
NCI Thesaurus
OMIM
MGI genotype (from TogoID)
WikiPathways (from TogoID)
Related Genes
Displaying entries 131 - 140 of 217 in total
Gene ID Gene Symbol Description Source
6609 SMPD1 sphingomyelin phosphodiesterase 1
6646 SOAT1 sterol O-acyltransferase 1
6715 SRD5A1 steroid 5 alpha-reductase 1
6783 SULT1E1 sulfotransferase family 1E member 1
7357 UGCG UDP-glucose ceramide glucosyltransferase
7412 VCAM1 vascular cell adhesion molecule 1
7903 ST8SIA4 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4
7957 EPM2A EPM2A glucan phosphatase, laforin
7991 TUSC3 tumor suppressor candidate 3
8398 PLA2G6 phospholipase A2 group VI
Displaying 1 entry
Gene ID Gene Symbol Description Source
15558 Htr2a 5-hydroxytryptamine (serotonin) receptor 2A
Displaying 1 entry
Gene ID Gene Symbol Description Source
29595 Htr2a 5-hydroxytryptamine receptor 2A
Related Glycoprotein
Displaying entry 161 - 161 of 161 in total
UniProt ID Protein Name Source
Q9Y6A2 Cholesterol 24-hydroxylase

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Last updated: August 19, 2024