acute chest syndrome

Summary
Synonym
  • acute chest syndrome in sickle cell disease
Definition
A lung disease that involves a vasoocclusive crisis of the pulmonary vasculature seen in patients with sickle cell anemia. The crisis is initiated by a lung infection, and the resulting inflammation and loss of oxygen tension leads to sickling of red cells and further vasoocclusion. The disease has_symptom fever, has_symptom pleuritic chest pain, has_symptom tachypnea, has_symptom cough, has_symptom hypoxemia, has_symptom marked leukocytosis, and has_symptom diffuse infiltrates on chest radiograph.
Super Class
lung disease
External Links
Disease Ontology
DOID:1584
Mondo Disease Ontology
MeSH
UMLS
NCI Thesaurus
Related Genes
Displaying entries 21 - 30 of 51 in total
Gene ID Gene Symbol Description Source
3897 L1CAM L1 cell adhesion molecule
3931 LCAT lecithin-cholesterol acyltransferase
3958 LGALS3 galectin 3
3988 LIPA lipase A, lysosomal acid type
3992 FADS1 fatty acid desaturase 1
4023 LPL lipoprotein lipase
4968 OGG1 8-oxoguanine DNA glycosylase
4973 OLR1 oxidized low density lipoprotein receptor 1
5130 PCYT1A phosphate cytidylyltransferase 1A, choline
5320 PLA2G2A phospholipase A2 group IIA

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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: August 19, 2024