acute chest syndrome

Summary
Synonym
  • acute chest syndrome in sickle cell disease
Definition
A lung disease that involves a vasoocclusive crisis of the pulmonary vasculature seen in patients with sickle cell anemia. The crisis is initiated by a lung infection, and the resulting inflammation and loss of oxygen tension leads to sickling of red cells and further vasoocclusion. The disease has_symptom fever, has_symptom pleuritic chest pain, has_symptom tachypnea, has_symptom cough, has_symptom hypoxemia, has_symptom marked leukocytosis, and has_symptom diffuse infiltrates on chest radiograph.
Super Class
lung disease
External Links
Disease Ontology
DOID:1584
Mondo Disease Ontology
MeSH
UMLS
NCI Thesaurus
Related Genes
Displaying entries 1 - 10 of 51 in total
Gene ID Gene Symbol Description Source
28 ABO ABO, alpha 1-3-N-acetylgalactosaminyltransferase and alpha 1-3-galactosyltransferase
31 ACACA acetyl-CoA carboxylase alpha
32 ACACB acetyl-CoA carboxylase beta
217 ALDH2 aldehyde dehydrogenase 2 family member
240 ALOX5 arachidonate 5-lipoxygenase
410 ARSA arylsulfatase A
929 CD14 CD14 molecule
960 CD44 CD44 molecule (IN blood group)
1116 CHI3L1 chitinase 3 like 1
1543 CYP1A1 cytochrome P450 family 1 subfamily A member 1
Related Glycoprotein
Displaying entry 41 - 41 of 41 in total
UniProt ID Protein Name Source
Q9Y5X9 Endothelial lipase

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Last updated: August 19, 2024