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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
asthma
Summary
- Synonym
-
- bronchial hyperreactivity
- chronic obstructive asthma
- chronic obstructive asthma with acute exacerbation
- chronic obstructive asthma with status asthmaticus
- Definition
- A bronchial disease that is characterized by chronic inflammation and narrowing of the airways, which is caused by a combination of environmental and genetic factors. The disease has_symptom recurring periods of wheezing (a whistling sound while breathing), has_symptom chest tightness, has_symptom shortness of breath, has_symptom mucus production and has_symptom coughing.
- Super Class
- bronchial disease
Related Genes
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 5293 | PIK3CD | phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta | |
| 5294 | PIK3CG | phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma | |
| 5319 | PLA2G1B | phospholipase A2 group IB | |
| 5320 | PLA2G2A | phospholipase A2 group IIA | |
| 5321 | PLA2G4A | phospholipase A2 group IVA | |
| 5329 | PLAUR | plasminogen activator, urokinase receptor | |
| 5335 | PLCG1 | phospholipase C gamma 1 | |
| 5337 | PLD1 | phospholipase D1 | |
| 5476 | CTSA | cathepsin A | |
| 5553 | PRG2 | proteoglycan 2, pro eosinophil major basic protein |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 12654 | Chi3l1 | chitinase 3 like 1 | |
| 12655 | Chil3 | chitinase-like 3 | |
| 16182 | Il18r1 | interleukin 18 receptor 1 | |
| 16846 | Lep | leptin | |
| 17082 | Il1rl1 | interleukin 1 receptor-like 1 | |
| 18654 | Pgf | placental growth factor | |
| 18783 | Pla2g4a | phospholipase A2, group IVA (cytosolic, calcium-dependent) | |
| 21897 | Tlr1 | toll-like receptor 1 | |
| 21898 | Tlr4 | toll-like receptor 4 | |
| 21899 | Tlr6 | toll-like receptor 6 |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 24835 | Tnf | tumor necrosis factor | |
| 25556 | Il1rl1 | interleukin 1 receptor-like 1 | |
| 25591 | Parp1 | poly (ADP-ribose) polymerase 1 | |
| 25608 | Lep | leptin | |
| 29260 | Tlr4 | toll-like receptor 4 | |
| 65270 | Abo3 | histo-blood group ABO system transferase 3 | |
| 89824 | Chi3l1 | chitinase 3 like 1 | |
| 94203 | Pgf | placental growth factor | |
| 113901 | Chia | chitinase, acidic | |
| 296504 | Abo2 | histo-blood group ABO system transferase 2 |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 31926 | Idgf4 | Imaginal disc growth factor 4 | |
| 34978 | Idgf1 | Imaginal disc growth factor 1 | |
| 34979 | Idgf2 | Imaginal disc growth factor 2 | |
| 34981 | Idgf3 | Imaginal disc growth factor 3 | |
| 36868 | Idgf6 | Imaginal disc growth factor 6 | |
| 37104 | Idgf5 | Imaginal disc growth factor 5 | |
| 38223 | Cht2 | Chitinase 2 | |
| 38973 | se | sepia | |
| 43222 | Tl | Toll | |
| 3355109 | Parp1 | Poly-(ADP-ribose) polymerase 1 |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 387303 | gbgt1l4 | globoside alpha-1,3-N-acetylgalactosaminyltransferase 1, like 4 | |
| 447881 | gbgt1l3 | globoside alpha-1,3-N-acetylgalactosaminyltransferase 1, like 3 | |
| 560788 | parp1 | poly (ADP-ribose) polymerase 1 | |
| 563897 | gbgt1l5 | globoside alpha-1,3-N-acetylgalactosaminyltransferase 1, like 5 | |
| 566487 | gbgt1l2 | globoside alpha-1,3-N-acetylgalactosaminyltransferase 1, like 2 | |
| 100005565 | gbgt1l8 | globoside alpha-1,3-N-acetylgalactosaminyltransferase 1, like 8 | |
| 100005704 | gbgt1l9 | globoside alpha-1,3-N-acetylgalactosaminyltransferase 1, like 9 |
| Gene ID | Gene Symbol | Description | Source | Organism |
|---|---|---|---|---|
| 495825 | abo.3.L | ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase) L homeolog | Xenopus laevis (African clawed frog) | |
| 549437 | abo.3 | ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase) gene 3 | Xenopus tropicalis (tropical clawed frog) | |
| 549858 | abo.2 | ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase) gene 2 | Xenopus tropicalis (tropical clawed frog) | |
| 550054 | abo.1 | ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase) gene 1 | Xenopus tropicalis (tropical clawed frog) | |
| 100497509 | abo.4 | ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase) gene 4 | Xenopus tropicalis (tropical clawed frog) | |
| 108698211 | abo.2.L | ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase) gene 2 L homeolog | Xenopus laevis (African clawed frog) | |
| 108698863 | abo.4.L | ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase) gene 4 L homeolog | Xenopus laevis (African clawed frog) |
Related Glycoprotein
| UniProt ID | Protein Name | Source |
|---|---|---|
| P09104 | Gamma-enolase | |
| P09326 | CD48 antigen | |
| P09382 | Galectin-1 | |
| P09525 | Annexin A4 | |
| P09848 | Lactase/phlorizin hydrolase | |
| P09874 | Poly [ADP-ribose] polymerase 1 | |
| P09960 | Leukotriene A-4 hydrolase | |
| P10619 | Lysosomal protective protein | |
| P11226 | Mannose-binding protein C | |
| P11413 | Glucose-6-phosphate 1-dehydrogenase |
- The Human Phenotype Ontology
| HPO ID | HPO Term |
|---|---|
| HP:0001426 | Non-Mendelian inheritance |
| HP:0000006 | Autosomal dominant inheritance |
| HP:0002099 | Asthma |
