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asthma
Summary
- Synonym
-
- bronchial hyperreactivity
- chronic obstructive asthma
- chronic obstructive asthma with acute exacerbation
- chronic obstructive asthma with status asthmaticus
- Definition
- A bronchial disease that is characterized by chronic inflammation and narrowing of the airways, which is caused by a combination of environmental and genetic factors. The disease has_symptom recurring periods of wheezing (a whistling sound while breathing), has_symptom chest tightness, has_symptom shortness of breath, has_symptom mucus production and has_symptom coughing.
- Super Class
- bronchial disease
Related Genes
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 7941 | PLA2G7 | phospholipase A2 group VII | |
| 8518 | ELP1 | elongator acetyltransferase complex subunit 1 | |
| 8809 | IL18R1 | interleukin 18 receptor 1 | |
| 9173 | IL1RL1 | interleukin 1 receptor like 1 | |
| 10333 | TLR6 | toll like receptor 6 | |
| 10800 | CYSLTR1 | cysteinyl leukotriene receptor 1 | |
| 11213 | IRAK3 | interleukin 1 receptor associated kinase 3 | |
| 11251 | PTGDR2 | prostaglandin D2 receptor 2 | |
| 27159 | CHIA | chitinase acidic | |
| 54106 | TLR9 | toll like receptor 9 |
Related Glycoprotein
| UniProt ID | Protein Name | Source |
|---|---|---|
| P29460 | Interleukin-12 subunit beta | |
| P29474 | Nitric oxide synthase 3 | |
| P29475 | Nitric oxide synthase 1 | |
| P30411 | B2 bradykinin receptor | |
| P30542 | Adenosine receptor A1 | |
| P31645 | Sodium-dependent serotonin transporter | |
| P34998 | Corticotropin-releasing factor receptor 1 | |
| P35225 | Interleukin-13 | |
| P35228 | Nitric oxide synthase, inducible | |
| P35247 | Pulmonary surfactant-associated protein D |
| UniProt ID | Protein Name | Source |
|---|---|---|
| P16382 | Interleukin-4 receptor subunit alpha | |
| Q9D2L4 | Integrin beta |
| UniProt ID | Protein Name | Source |
|---|---|---|
| P01283 | VIP peptides | |
| P06399 | Fibrinogen alpha chain | |
| P08650 | Complement C5 | |
| P25023 | B2 bradykinin receptor | |
| P25095 | Type-1 angiotensin II receptor A | |
| P26897 | Interleukin-2 receptor subunit alpha | |
| P29456 | Interleukin-10 | |
| P29994 | Inositol 1,4,5-trisphosphate-gated calcium channel ITPR1 | |
| P34980 | Prostaglandin E2 receptor EP3 subtype | |
| P35763 | Perforin-1 |
| UniProt ID | Protein Name | Source |
|---|---|---|
| Q9VP04 | ORM1-like protein |
- The Human Phenotype Ontology
| HPO ID | HPO Term |
|---|---|
| HP:0001426 | Non-Mendelian inheritance |
| HP:0000006 | Autosomal dominant inheritance |
| HP:0002099 | Asthma |
