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asthma
Summary
- Synonym
-
- bronchial hyperreactivity
- chronic obstructive asthma
- chronic obstructive asthma with acute exacerbation
- chronic obstructive asthma with status asthmaticus
- Definition
- A bronchial disease that is characterized by chronic inflammation and narrowing of the airways, which is caused by a combination of environmental and genetic factors. The disease has_symptom recurring periods of wheezing (a whistling sound while breathing), has_symptom chest tightness, has_symptom shortness of breath, has_symptom mucus production and has_symptom coughing.
- Super Class
- bronchial disease
Related Genes
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 3605 | IL17A | interleukin 17A | |
| 3690 | ITGB3 | integrin subunit beta 3 | |
| 3958 | LGALS3 | galectin 3 | |
| 4049 | LTA | lymphotoxin alpha | |
| 4153 | MBL2 | mannose binding lectin 2 | |
| 4210 | MEFV | MEFV innate immunity regulator, pyrin | |
| 4282 | MIF | macrophage migration inhibitory factor | |
| 4318 | MMP9 | matrix metallopeptidase 9 | |
| 4353 | MPO | myeloperoxidase | |
| 4583 | MUC2 | mucin 2, oligomeric mucus/gel-forming |
Related Glycoprotein
| UniProt ID | Protein Name | Source |
|---|---|---|
| Q9Y5Y4 | Prostaglandin D2 receptor 2 | |
| Q9Y616 | Interleukin-1 receptor-associated kinase 3 |
| UniProt ID | Protein Name | Source |
|---|---|---|
| P16382 | Interleukin-4 receptor subunit alpha | |
| Q9D2L4 | Integrin beta |
| UniProt ID | Protein Name | Source |
|---|---|---|
| P01283 | VIP peptides | |
| P06399 | Fibrinogen alpha chain | |
| P08650 | Complement C5 | |
| P25023 | B2 bradykinin receptor | |
| P25095 | Type-1 angiotensin II receptor A | |
| P26897 | Interleukin-2 receptor subunit alpha | |
| P29456 | Interleukin-10 | |
| P29994 | Inositol 1,4,5-trisphosphate-gated calcium channel ITPR1 | |
| P34980 | Prostaglandin E2 receptor EP3 subtype | |
| P35763 | Perforin-1 |
| UniProt ID | Protein Name | Source |
|---|---|---|
| Q9VP04 | ORM1-like protein |
- The Human Phenotype Ontology
| HPO ID | HPO Term |
|---|---|
| HP:0001426 | Non-Mendelian inheritance |
| HP:0000006 | Autosomal dominant inheritance |
| HP:0002099 | Asthma |
