Submissions
GlyTouCan
Glycan Structure Repository
GlyComb
Glycoconjugate Repository
GlycoPOST
Glycomics MS raw data Repository
UniCarb-DR
Glycomics MS Repository for glycan annotations from GlycoWorkbench
LM-GlycoRepo
Repository for lectin-assisted multimodality data
Resources Genes Glycoproteins Lectins Glycolipids Glycans Pathways Diseases Organisms
All Resources
Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Other Information
Release Statistics Download
Tools
SugarDrawer GlycanBuilder Glycan Converters GlycoMaple GlycomeAtlas LM-GlycomeAtlas GALAXY MCAW GlycoSim GRable
Search Tools
Cross Search Glycan Search Publication Search Programmatic Access
Standards Ontologies Notations
pulmonary fibrosis

Summary
Synonym
  • Fibrosis of lung
Definition
An interstitial lung disease that is characterized by destruction, scarring, and thickening of the interstitial lung tissues and progressive pulmonary function loss in a restrictive pattern, has_symptom progressive shortness of breath, fatigue, and chronic cough, possibly has_material_basis_in exposure to certain chemicals, autoimmune conditions, and radiation.
Super Class
interstitial lung disease
Disease Ontology
DOID:3770
Mondo Disease Ontology
MeSH
UMLS
NCI Thesaurus
MGI genotype (from TogoID)
WikiPathways (from TogoID)
Related Genes
Displaying entries 1 - 10 of 69 in total
Gene ID Gene Symbol Description Source
177 AGER advanced glycosylation end-product specific receptor
182 JAG1 jagged canonical Notch ligand 1
183 AGT angiotensinogen
240 ALOX5 arachidonate 5-lipoxygenase
301 ANXA1 annexin A1
572 BAD BCL2 associated agonist of cell death
623 BDKRB1 bradykinin receptor B1
627 BDNF brain derived neurotrophic factor
847 CAT catalase
948 CD36 CD36 molecule (CD36 blood group)
Displaying entries 21 - 30 of 56 in total
Gene ID Gene Symbol Description Source
15516 Hsp90ab1 heat shock protein 90 alpha (cytosolic), class B member 1
15894 Icam1 intercellular adhesion molecule 1
16009 Igfbp3 insulin-like growth factor binding protein 3
16163 Il13 interleukin 13
16168 Il15 interleukin 15
16171 Il17a interleukin 17A
16175 Il1a interleukin 1 alpha
16181 Il1rn interleukin 1 receptor antagonist
16182 Il18r1 interleukin 18 receptor 1
16189 Il4 interleukin 4
Displaying entries 11 - 20 of 42 in total
Gene ID Gene Symbol Description Source
24835 Tnf tumor necrosis factor
25267 Pdgfra platelet derived growth factor receptor alpha
25464 Icam1 intercellular adhesion molecule 1
25496 Notch1 notch receptor 1
25670 Il15 interleukin 15
29146 Jag1 jagged canonical Notch ligand 1
29393 Col1a1 collagen type I alpha 1 chain
29397 Ccl11 C-C motif chemokine ligand 11
29436 Tfpi tissue factor pathway inhibitor
29527 Ptgs2 prostaglandin-endoperoxide synthase 2
Displaying entries 11 - 16 of 16 in total
Gene ID Gene Symbol Description Source
37455 Egfr Epidermal growth factor receptor
37892 mAChR-A muscarinic Acetylcholine Receptor, A-type
38868 Snmp2 Sensory neuron membrane protein 2
42514 Snmp1 Sensory neuron membrane protein 1
43275 Ser Serrate
251900 GlcAT-I Glucuronyltransferase I
Displaying all 8 entries
Gene ID Gene Symbol Description Source
30718 notch1a notch receptor 1a
58133 ngfb nerve growth factor b (beta polypeptide)
114424 cdh1 cadherin 1, type 1, E-cadherin (epithelial)
140421 jag1a jagged canonical Notch ligand 1a
386856 pdgfra platelet-derived growth factor receptor, alpha polypeptide
548607 b3gat1a beta-1,3-glucuronyltransferase 1 (glucuronosyltransferase P) a
565980 ace angiotensin I converting enzyme (peptidyl-dipeptidase A) 1
100332644 b3gat1b beta-1,3-glucuronyltransferase 1 (glucuronosyltransferase P) b
Displaying all 6 entries
Gene ID Gene Symbol Description Source Organism
397778 tgfb1.L transforming growth factor beta 1 L homeolog Xenopus laevis (African clawed frog)
100037842 notch1 notch 1 receptor Xenopus tropicalis (tropical clawed frog)
100037907 b3gat1 beta-1,3-glucuronyltransferase 1 Xenopus tropicalis (tropical clawed frog)
100144634 ace angiotensin I converting enzyme Xenopus tropicalis (tropical clawed frog)
100337618 cdh1.S cadherin 1, type 1 S homeolog Xenopus laevis (African clawed frog)
108709389 ngf.S nerve growth factor S homeolog Xenopus laevis (African clawed frog)
Displaying entries 1 - 10 of 15 in total
Gene ID Gene Symbol Description Source
174462 let-23 Receptor tyrosine-protein kinase let-23;receptor protein-tyrosine kinase
174517 sqv-8 Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase sqv-8
175182 ver-1 Protein ver-1
175383 zmp-2 Matrix metalloproteinase-B
175781 daf-4 Cell surface receptor daf-4;Serine/threonine-protein kinase receptor;receptor protein serine/threonine kinase
176286 glp-1 glp-1/Notch intracellular domain
177343 skn-1 BZIP domain-containing protein;Protein skinhead-1
178672 srp-3 Serpin domain-containing protein
179197 cri-2 Putative metalloproteinase inhibitor tag-225
179962 gar-3 Muscarinic acetylcholine receptor gar-3
Displaying all 2 entries
Gene ID Gene Symbol Description Source
851977 CTS2 putative chitinase
853177 APL6 Apl6p
About Release Notes Help Feedback

Click here to visit the beta site.

International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

Logo License Policies Site Map

Contact: support@glycosmos.org

This work is licensed under Creative Commons Attribution 4.0 International

GlyCosmos Portal v4.1.0

Last updated: December 9, 2024