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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
pulmonary fibrosis
Summary
- Synonym
-
- Fibrosis of lung
- Definition
- An interstitial lung disease that is characterized by destruction, scarring, and thickening of the interstitial lung tissues and progressive pulmonary function loss in a restrictive pattern, has_symptom progressive shortness of breath, fatigue, and chronic cough, possibly has_material_basis_in exposure to certain chemicals, autoimmune conditions, and radiation.
- Super Class
- interstitial lung disease
External Links
- Disease Ontology
- DOID:3770
- Mondo Disease Ontology
- MeSH
- UMLS
- NCI Thesaurus
Related Genes
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 177 | AGER | advanced glycosylation end-product specific receptor | |
| 182 | JAG1 | jagged canonical Notch ligand 1 | |
| 183 | AGT | angiotensinogen | |
| 240 | ALOX5 | arachidonate 5-lipoxygenase | |
| 301 | ANXA1 | annexin A1 | |
| 572 | BAD | BCL2 associated agonist of cell death | |
| 623 | BDKRB1 | bradykinin receptor B1 | |
| 627 | BDNF | brain derived neurotrophic factor | |
| 847 | CAT | catalase | |
| 948 | CD36 | CD36 molecule (CD36 blood group) |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 50701 | Elane | elastase, neutrophil expressed | |
| 58861 | Cysltr1 | cysteinyl leukotriene receptor 1 | |
| 74006 | Dnm1l | dynamin 1-like | |
| 76898 | B3gat1 | beta-1,3-glucuronyltransferase 1 | |
| 81897 | Tlr9 | toll-like receptor 9 | |
| 83995 | Mmp1a | matrix metallopeptidase 1a (interstitial collagenase) |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 24835 | Tnf | tumor necrosis factor | |
| 25267 | Pdgfra | platelet derived growth factor receptor alpha | |
| 25464 | Icam1 | intercellular adhesion molecule 1 | |
| 25496 | Notch1 | notch receptor 1 | |
| 25670 | Il15 | interleukin 15 | |
| 29146 | Jag1 | jagged canonical Notch ligand 1 | |
| 29393 | Col1a1 | collagen type I alpha 1 chain | |
| 29397 | Ccl11 | C-C motif chemokine ligand 11 | |
| 29436 | Tfpi | tissue factor pathway inhibitor | |
| 29527 | Ptgs2 | prostaglandin-endoperoxide synthase 2 |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 31293 | N | Notch | |
| 31926 | Idgf4 | Imaginal disc growth factor 4 | |
| 34189 | Acer | Angiotensin-converting enzyme-related | |
| 34282 | GlcAT-S | Glucuronyltransferase S | |
| 34805 | Ance | Angiotensin converting enzyme | |
| 34978 | Idgf1 | Imaginal disc growth factor 1 | |
| 34979 | Idgf2 | Imaginal disc growth factor 2 | |
| 34981 | Idgf3 | Imaginal disc growth factor 3 | |
| 36868 | Idgf6 | Imaginal disc growth factor 6 | |
| 37104 | Idgf5 | Imaginal disc growth factor 5 |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 30718 | notch1a | notch receptor 1a | |
| 58133 | ngfb | nerve growth factor b (beta polypeptide) | |
| 114424 | cdh1 | cadherin 1, type 1, E-cadherin (epithelial) | |
| 140421 | jag1a | jagged canonical Notch ligand 1a | |
| 386856 | pdgfra | platelet-derived growth factor receptor, alpha polypeptide | |
| 548607 | b3gat1a | beta-1,3-glucuronyltransferase 1 (glucuronosyltransferase P) a | |
| 565980 | ace | angiotensin I converting enzyme (peptidyl-dipeptidase A) 1 | |
| 100332644 | b3gat1b | beta-1,3-glucuronyltransferase 1 (glucuronosyltransferase P) b |
| Gene ID | Gene Symbol | Description | Source | Organism |
|---|---|---|---|---|
| 397778 | tgfb1.L | transforming growth factor beta 1 L homeolog | Xenopus laevis (African clawed frog) | |
| 100037842 | notch1 | notch 1 receptor | Xenopus tropicalis (tropical clawed frog) | |
| 100037907 | b3gat1 | beta-1,3-glucuronyltransferase 1 | Xenopus tropicalis (tropical clawed frog) | |
| 100144634 | ace | angiotensin I converting enzyme | Xenopus tropicalis (tropical clawed frog) | |
| 100337618 | cdh1.S | cadherin 1, type 1 S homeolog | Xenopus laevis (African clawed frog) | |
| 108709389 | ngf.S | nerve growth factor S homeolog | Xenopus laevis (African clawed frog) |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 174462 | let-23 | Receptor tyrosine-protein kinase let-23;receptor protein-tyrosine kinase | |
| 174517 | sqv-8 | Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase sqv-8 | |
| 175182 | ver-1 | Protein ver-1 | |
| 175383 | zmp-2 | Matrix metalloproteinase-B | |
| 175781 | daf-4 | Cell surface receptor daf-4;Serine/threonine-protein kinase receptor;receptor protein serine/threonine kinase | |
| 176286 | glp-1 | glp-1/Notch intracellular domain | |
| 177343 | skn-1 | BZIP domain-containing protein;Protein skinhead-1 | |
| 178672 | srp-3 | Serpin domain-containing protein | |
| 179197 | cri-2 | Putative metalloproteinase inhibitor tag-225 | |
| 179962 | gar-3 | Muscarinic acetylcholine receptor gar-3 |
