systemic scleroderma

Summary
Synonym
  • Scleroderma
  • Scleroderma syndrome
  • progressive systemic sclerosis
  • systemic sclerosis
Definition
A scleroderma that is characterized by fibrosis (or hardening) of the skin and major organs, as well as vascular alterations, and autoantibodies.
Super Class
scleroderma
Disease Ontology
DOID:418
Mondo Disease Ontology
MeSH
UMLS
NCI Thesaurus
OMIM
GARD
MGI genotype (from TogoID)
Related Genes
Displaying entries 51 - 60 of 66 in total
Gene ID Gene Symbol Description Source
5950 RBP4 retinol binding protein 4
6347 CCL2 C-C motif chemokine ligand 2
6376 CX3CL1 C-X3-C motif chemokine ligand 1
6414 SELENOP selenoprotein P
6556 SLC11A1 solute carrier family 11 member 1
6775 STAT4 signal transducer and activator of transcription 4
7046 TGFBR1 transforming growth factor beta receptor 1
7422 VEGFA vascular endothelial growth factor A
7450 VWF von Willebrand factor
9466 IL27RA interleukin 27 receptor subunit alpha
Displaying entries 31 - 40 of 57 in total
Gene ID Gene Symbol Description Source
16189 Il4 interleukin 4
16456 F11r F11 receptor
16542 Kdr kinase insert domain protein receptor
16992 Lta lymphotoxin A
17329 Cxcl9 C-X-C motif chemokine ligand 9
17395 Mmp9 matrix metallopeptidase 9
17829 Muc1 mucin 1, transmembrane
18049 Ngf nerve growth factor
18132 Notch4 notch 4
18173 Slc11a1 solute carrier family 11 (proton-coupled divalent metal ion transporters), member 1
Displaying entries 31 - 36 of 36 in total
Gene ID Gene Symbol Description Source
116562 Il2 interleukin 2
287287 Il4 interleukin 4
310738 Ngf nerve growth factor
315509 Jam3 junctional adhesion molecule 3
316519 Slc11a1 solute carrier family 11 member 1
360918 Pf4 platelet factor 4
Displaying all 10 entries
Gene ID Gene Symbol Description Source
31926 Idgf4 Imaginal disc growth factor 4
34091 Spn28Dc Serpin 28Dc
34189 Acer Angiotensin-converting enzyme-related
34805 Ance Angiotensin converting enzyme
34978 Idgf1 Imaginal disc growth factor 1
34979 Idgf2 Imaginal disc growth factor 2
34981 Idgf3 Imaginal disc growth factor 3
36868 Idgf6 Imaginal disc growth factor 6
37104 Idgf5 Imaginal disc growth factor 5
42490 Mvl Malvolio
Displaying all 5 entries
Gene ID Gene Symbol Description Source
30682 vegfaa vascular endothelial growth factor Aa
58133 ngfb nerve growth factor b (beta polypeptide)
554230 kdr kinase insert domain receptor (a type III receptor tyrosine kinase)
565980 ace angiotensin I converting enzyme (peptidyl-dipeptidase A) 1
791973 cxcr3.2 chemokine (C-X-C motif) receptor 3, tandem duplicate 2
Displaying all 2 entries
Gene ID Gene Symbol Description Source Organism
100144634 ace angiotensin I converting enzyme Xenopus tropicalis (tropical clawed frog)
108709389 ngf.S nerve growth factor S homeolog Xenopus laevis (African clawed frog)
Displaying entries 1 - 10 of 18 in total
Gene ID Gene Symbol Description Source
174044 sma-6 Serine/threonine-protein kinase receptor sma-6
175182 ver-1 Protein ver-1
176076 fbn-1 EGF-like domain-containing protein
176282 lin-12 lin-12/Notch intracellular domain
176286 glp-1 glp-1/Notch intracellular domain
176829 daf-1 Cell surface receptor daf-1
177044 smf-3 NRAMP-like transporter smf-3
178672 srp-3 Serpin domain-containing protein
178748 zmp-3 Matrix metalloproteinase-C
179991 zmp-4 Hemopexin;Peptidase metallopeptidase domain-containing protein
Displaying all 2 entries
Gene ID Gene Symbol Description Source
850721 SMF3 putative divalent metal ion transporter SMF3
851977 CTS2 putative chitinase

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Last updated: December 9, 2024