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Standards Ontologies Notations
human immunodeficiency virus infectious disease

Summary
Synonym
  • HIV infection
Definition
A viral infectious disease that results in destruction of immune system, leading to life-threatening opportunistic infections and cancers, has_material_basis_in Human immunodeficiency virus 1 or has_material_basis_in Human immunodeficiency virus 2, which are transmitted by sexual contact, transmitted by transfer of blood, semen, vaginal fluid, pre-ejaculate, or breast milk, transmitted by congenital method, and transmitted by contaminated needles. The virus infects helper T cells (CD4+ T cells) which are directly or indirectly destroyed, macrophages, and dendritic cells. The infection has symptom diarrhea, has symptom fatigue, has symptom fever, has symptom vaginal yeast infection, has symptom headache, has symptom mouth sores, has symptom muscle aches, has symptom sore throat, and has symptom swollen lymph glands.
Super Class
viral infectious disease
Disease Ontology
DOID:526
Mondo Disease Ontology
MeSH
UMLS
NCI Thesaurus
WikiPathways (from TogoID)
Related Genes
Displaying entries 1 - 10 of 56 in total
Gene ID Gene Symbol Description Source
355 FAS Fas cell surface death receptor
472 ATM ATM serine/threonine kinase
718 C3 complement C3
958 CD40 CD40 molecule
959 CD40LG CD40 ligand
968 CD68 CD68 molecule
1234 CCR5 C-C motif chemokine receptor 5
1380 CR2 complement C3d receptor 2
1555 CYP2B6 cytochrome P450 family 2 subfamily B member 6
2048 EPHB2 EPH receptor B2
Displaying entries 61 - 62 of 62 in total
Gene ID Gene Symbol Description Source
268373 Ppia peptidylprolyl isomerase A
100504404 H2-Ea histocompatibility 2, class II antigen E alpha
Displaying entries 1 - 10 of 25 in total
Gene ID Gene Symbol Description Source
24232 C3 complement C3
24536 Lepr leptin receptor
24588 Nefm neurofilament medium chain
24648 Serpina1 serpin family A member 1
24770 Ccl2 C-C motif chemokine ligand 2
24835 Tnf tumor necrosis factor
25325 Il10 interleukin 10
25419 Crp C-reactive protein
25518 Ppia peptidylprolyl isomerase A
25601 Oprm1 opioid receptor, mu 1
Displaying all 4 entries
Gene ID Gene Symbol Description Source
34091 Spn28Dc Serpin 28Dc
36016 Sting sting
36428 Mdr49 Multi drug resistance 49
38726 Mdr65 Multi drug resistance 65
Displaying all 4 entries
Gene ID Gene Symbol Description Source
173794 vab-1 Ephrin receptor 1
178215 pgp-1 Multidrug resistance protein pgp-1
181326 pgp-3 Multidrug resistance protein pgp-3
188252 lev-9 Protein lev-9
Displaying all 2 entries
Gene ID Gene Symbol Description Source
851665 RLI1 Fe-S cluster-binding ribosome biosynthesis protein
853671 STE6 ATP-binding cassette a-factor transporter STE6
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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: December 9, 2024