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Standards Ontologies Notations
type 1 diabetes mellitus

Summary
Synonym
  • IDDM
  • insulin-dependent diabetes mellitus
  • type I diabetes mellitus
Definition
A diabetes mellitus that is characterized by destruction of pancreatic beta cells resulting in absent or extremely low insulin production.
Super Class
autoimmune disease of endocrine system diabetes mellitus
External Links
Disease Ontology
DOID:9744
Mondo Disease Ontology
MeSH
UMLS
NCI Thesaurus
OMIM
GARD
MGI genotype (from TogoID)
Related Genes
Displaying entries 1 - 10 of 176 in total
Gene ID Gene Symbol Description Source
28 ABO ABO, alpha 1-3-N-acetylgalactosaminyltransferase and alpha 1-3-galactosyltransferase
43 ACHE acetylcholinesterase (Yt blood group)
128 ADH5 alcohol dehydrogenase 5 (class III), chi polypeptide
142 PARP1 poly(ADP-ribose) polymerase 1
175 AGA aspartylglucosaminidase
176 ACAN aggrecan
217 ALDH2 aldehyde dehydrogenase 2 family member
224 ALDH3A2 aldehyde dehydrogenase 3 family member A2
231 AKR1B1 aldo-keto reductase family 1 member B
239 ALOX12 arachidonate 12-lipoxygenase, 12S type
Displaying entries 11 - 17 of 17 in total
Gene ID Gene Symbol Description Source
18609 Pdx1 pancreatic and duodenal homeobox 1
21898 Tlr4 toll-like receptor 4
21926 Tnf tumor necrosis factor
24088 Tlr2 toll-like receptor 2
71665 Fuca1 fucosidase, alpha-L- 1, tissue
233781 Xylt1 xylosyltransferase 1
394436 Ugt1a1 UDP glucuronosyltransferase 1 family, polypeptide A1
Displaying entries 1 - 10 of 14 in total
Gene ID Gene Symbol Description Source
24375 Fuca1 alpha-L-fucosidase 1
24377 G6pd glucose-6-phosphate dehydrogenase
24476 Iapp islet amyloid polypeptide
24483 Igf2 insulin-like growth factor 2
24505 Ins1 insulin 1
24506 Ins2 insulin 2
24835 Tnf tumor necrosis factor
24861 Ugt1a1 UDP glucuronosyltransferase family 1 member A1
24925 Adrb1 adrenoceptor beta 1
25668 Cd38 CD38 molecule
Displaying entries 21 - 30 of 31 in total
Gene ID Gene Symbol Description Source
44058 Ugt36A1 UDP-glycosyltransferase family 36 member A1
53501 Ugt304A1 UDP-glycosyltransferase family 304 member A1
53502 Ugt302K1 UDP-glycosyltransferase family 302 member K1
53503 Ugt303A1 UDP-glycosyltransferase family 303 member A1
53506 Ugt35E2 UDP-glycosyltransferase family 35 member E2
53507 Ugt35C1 UDP-glycosyltransferase family 35 member C1
53511 Ugt37D1 UDP-glycosyltransferase family 37 member D1
53512 Ugt37E1 UDP-glycosyltransferase family 37 member E1
53583 Ugt37C1 UDP-glycosyltransferase family 37 member C1
53584 Ugt37B1 UDP-glycosyltransferase family 37 member B1
Displaying all 4 entries
Gene ID Gene Symbol Description Source
30262 ins preproinsulin
406731 ugt1ab UDP glucuronosyltransferase 1 family a, b
560951 xylt1 xylosyltransferase I
100384891 ugt1a7 UDP glucuronosyltransferase 1 family, polypeptide A7
Displaying all 7 entries
Gene ID Gene Symbol Description Source Organism
378695 ins.L insulin L homeolog Xenopus laevis (African clawed frog)
378696 ins.S insulin S homeolog Xenopus laevis (African clawed frog)
444363 xylt1.L xylosyltransferase I L homeolog Xenopus laevis (African clawed frog)
100135191 ugt1a6 UDP glucuronosyltransferase 1 family, polypeptide A6 Xenopus tropicalis (tropical clawed frog)
100145490 xylt1 xylosyltransferase I Xenopus tropicalis (tropical clawed frog)
100489505 ugt1a1 UDP glucuronosyltransferase 1 family, polypeptide A1 Xenopus tropicalis (tropical clawed frog)
108703114 xylt1.S xylosyltransferase I S homeolog Xenopus laevis (African clawed frog)
Displaying all 5 entries
Gene ID Gene Symbol Description Source
175591 ugt-62 UDP-glucuronosyltransferase
178046 gspd-1 Glucose-6-phosphate 1-dehydrogenase
180628 cht-1 putative endochitinase
189173 W03G11.3 Putative alpha-L-fucosidase
190099 sqv-6 Xylosyltransferase sqv-6;protein xylosyltransferase
Displaying all 3 entries
Gene ID Gene Symbol Description Source
850886 ATG26 sterol 3-beta-glucosyltransferase
851977 CTS2 putative chitinase
855480 ZWF1 glucose-6-phosphate dehydrogenase
Related Glycoprotein
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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: August 19, 2024