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Discoidin domain-containing receptor A

Summary

Gene Symbol

ddr-1

Organism

Caenorhabditis elegans

External Links

NCBI Gene

180817

PubChem

180817

Alliance of Genome Resources

WB:WBGene00016104

Annotation

Keyword

ATP-binding
Cell membrane
Cell projection
Disulfide bond
Glycoprotein
Neurogenesis
Receptor
Reference proteome
Repeat
Signal
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
Q18163

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 7 in total

1

2

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GO Term	Evidence Code	PMID
protein phosphorylation	IEA
transmembrane receptor protein tyrosine kinase signaling pathway	IBA
nervous system development	IEA
motor neuron axon guidance	IGI	23147028
cell differentiation	IBA

GO Hierarchy

biological process

immune system process [inference]

immune response [inference]

innate immune response

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein phosphorylation

cellular metabolic process [inference]

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

phosphorylation [inference]

protein phosphorylation

primary metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein phosphorylation

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein phosphorylation

macromolecule modification [inference]

protein modification process [inference]

protein phosphorylation

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein phosphorylation

cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway [inference]

enzyme-linked receptor protein signaling pathway [inference]

transmembrane receptor protein tyrosine kinase signaling pathway

cellular metabolic process [inference]

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

phosphorylation [inference]

protein phosphorylation

cellular developmental process [inference]

cell differentiation

cellular component organization or biogenesis [inference]

cellular component organization [inference]

cell projection organization [inference]

plasma membrane bounded cell projection organization [inference]

neuron projection development [inference]

neuron projection guidance [inference]

axon guidance [inference]

motor neuron axon guidance

developmental process [inference]

anatomical structure development [inference]

system development [inference]

nervous system development

cellular developmental process [inference]

cell differentiation

biological process involved in interspecies interaction between organisms [inference]

response to other organism [inference]

defense response to other organism [inference]

innate immune response

response to stimulus [inference]

response to stress [inference]

defense response [inference]

defense response to other organism [inference]

innate immune response

immune response [inference]

innate immune response

response to external stimulus [inference]

response to external biotic stimulus [inference]

response to other organism [inference]

defense response to other organism [inference]

innate immune response

response to biotic stimulus [inference]

response to external biotic stimulus [inference]

response to other organism [inference]

defense response to other organism [inference]

innate immune response

biological regulation [inference]

regulation of biological process [inference]

positive regulation of biological process [inference]

positive regulation of cellular process [inference]

positive regulation of cellular component organization [inference]

positive regulation of cell projection organization [inference]

positive regulation of neuron projection development [inference]

positive regulation of neuron projection regeneration [inference]

positive regulation of axon regeneration

positive regulation of response to stimulus [inference]

positive regulation of response to external stimulus [inference]

positive regulation of axon regeneration

positive regulation of neuron projection regeneration [inference]

positive regulation of axon regeneration

positive regulation of response to wounding [inference]

positive regulation of axon regeneration

positive regulation of developmental process [inference]

positive regulation of neuron projection regeneration [inference]

positive regulation of axon regeneration

regulation of response to stimulus [inference]

regulation of response to external stimulus [inference]

positive regulation of response to external stimulus [inference]

positive regulation of axon regeneration

regulation of axon regeneration [inference]

positive regulation of axon regeneration

positive regulation of response to stimulus [inference]

positive regulation of response to external stimulus [inference]

positive regulation of axon regeneration

positive regulation of neuron projection regeneration [inference]

positive regulation of axon regeneration

positive regulation of response to wounding [inference]

positive regulation of axon regeneration

regulation of response to stress [inference]

regulation of cellular response to stress [inference]

regulation of neuron projection regeneration [inference]

regulation of axon regeneration [inference]

positive regulation of axon regeneration

positive regulation of neuron projection regeneration [inference]

positive regulation of axon regeneration

regulation of response to wounding [inference]

regulation of axon regeneration [inference]

positive regulation of axon regeneration

positive regulation of response to wounding [inference]

positive regulation of axon regeneration

regulation of developmental process [inference]

positive regulation of developmental process [inference]

positive regulation of neuron projection regeneration [inference]

positive regulation of axon regeneration

regulation of neuron projection regeneration [inference]

regulation of axon regeneration [inference]

positive regulation of axon regeneration

positive regulation of neuron projection regeneration [inference]

positive regulation of axon regeneration

regulation of cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway [inference]

enzyme-linked receptor protein signaling pathway [inference]

transmembrane receptor protein tyrosine kinase signaling pathway

positive regulation of cellular process [inference]

positive regulation of cellular component organization [inference]

positive regulation of cell projection organization [inference]

positive regulation of neuron projection development [inference]

positive regulation of neuron projection regeneration [inference]

positive regulation of axon regeneration

regulation of cellular component organization [inference]

regulation of cell projection organization [inference]

positive regulation of cell projection organization [inference]

positive regulation of neuron projection development [inference]

positive regulation of neuron projection regeneration [inference]

positive regulation of axon regeneration

regulation of plasma membrane bounded cell projection organization [inference]

regulation of neuron projection development [inference]

positive regulation of neuron projection development [inference]

positive regulation of neuron projection regeneration [inference]

positive regulation of axon regeneration

regulation of neuron projection regeneration [inference]

regulation of axon regeneration [inference]

positive regulation of axon regeneration

positive regulation of neuron projection regeneration [inference]

positive regulation of axon regeneration

positive regulation of cellular component organization [inference]

positive regulation of cell projection organization [inference]

positive regulation of neuron projection development [inference]

positive regulation of neuron projection regeneration [inference]

positive regulation of axon regeneration

regulation of cellular response to stress [inference]

regulation of neuron projection regeneration [inference]

regulation of axon regeneration [inference]

positive regulation of axon regeneration

positive regulation of neuron projection regeneration [inference]

positive regulation of axon regeneration

Displaying **all 5** entries
GO Term	Evidence Code	PMID
plasma membrane	IBA
plasma membrane	IEA
axon	IEA
cell projection	IEA
perikaryon	IEA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane [inference]

plasma membrane

cell projection

plasma membrane bounded cell projection [inference]

neuron projection [inference]

axon

perikaryon

Displaying **all 4** entries
GO Term	Evidence Code	PMID
protein kinase activity	IEA
non-membrane spanning protein tyrosine kinase activity	IBA
signaling receptor binding	IBA
ATP binding	IEA

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

transferase activity, transferring phosphorus-containing groups [inference]

kinase activity [inference]

protein kinase activity

protein tyrosine kinase activity [inference]

non-membrane spanning protein tyrosine kinase activity

phosphotransferase activity, alcohol group as acceptor [inference]

protein kinase activity

protein tyrosine kinase activity [inference]

non-membrane spanning protein tyrosine kinase activity

catalytic activity, acting on a protein [inference]

protein kinase activity

protein tyrosine kinase activity [inference]

non-membrane spanning protein tyrosine kinase activity

binding [inference]

protein binding [inference]

signaling receptor binding

small molecule binding [inference]

heterocyclic compound binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ion binding [inference]

anion binding [inference]

purine ribonucleoside triphosphate binding [inference]

ATP binding

organic cyclic compound binding [inference]

nucleoside phosphate binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleoside triphosphate binding [inference]

ATP binding

carbohydrate derivative binding [inference]

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

discoidin domain-containing receptor A

Functional Category

E: Amino acid transport and metabolism
O: Posttranslational modification, protein turnover, chaperones
T: Signal transduction mechanisms

Displaying 1 entry
Gene Ontology
ATP binding

Displaying **all 6** entries
InterPro
Coagulation factor 5/8 C-terminal domain
Discoidin domain-containing receptor 1/2, DS-like domain
Galactose-binding-like domain superfamily
Protein kinase domain
Protein kinase-like domain superfamily
Serine-threonine/tyrosine-protein kinase, catalytic domain

Alliance of Genome Resources

Expression

Displaying **all 2** entries
Location	References
axon	PMID:23147028
neuronal cell body	PMID:23147028

Ortholog

Displaying **all 6** entries
Species	Gene ID	Alliance of Genome Resources
Xenopus tropicalis	780	Xenbase:XB-GENE-485346
Xenopus tropicalis	4921	Xenbase:XB-GENE-5884186
Xenopus tropicalis	12305	Xenbase:XB-GENE-485346
Xenopus tropicalis	18214	Xenbase:XB-GENE-5884186
Xenopus tropicalis	180622	Xenbase:XB-GENE-5884186
Xenopus tropicalis	180817	Xenbase:XB-GENE-485346