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MIRAGE
angiotensin I converting enzyme
Summary
- Gene Symbol
-
- Ace
- Organism
- Rattus norvegicus (Norway rat)
Annotation
- Keyword
-
- Alternative promoter usage
- Calmodulin-binding
- Carboxypeptidase
- Cell membrane
- Cytoplasm
- Disulfide bond
- Glycoprotein
- Metal-binding
- Metalloprotease
- Phosphoprotein
- Reference proteome
- Repeat
- Secreted
- Signal
- Transmembrane helix
- Zinc
- Proteins
| UniProt | Protein Name |
|---|---|
| P47820 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| response to hypoxia | ||
| kidney development | ||
| kidney development | ||
| kidney development | ||
| kidney development |
GO Hierarchy
biological process
metabolic process [inference]
cellular process [inference]
developmental process [inference]
response to stimulus [inference]
biological regulation [inference]
regulation of biological process [inference]
regulation of metabolic process [inference]
regulation of localization [inference]
negative regulation of biological process [inference]
regulation of cellular process [inference]
| GO Term | Evidence Code | PMID |
|---|---|---|
| extracellular region | ||
| extracellular space | ||
| extracellular space | ||
| extracellular space | ||
| cytoplasm |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| actin binding | ||
| endopeptidase activity | ||
| carboxypeptidase activity | ||
| metallocarboxypeptidase activity | ||
| metallocarboxypeptidase activity |
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- angiotensin-converting enzyme
- Functional Category
-
- E: Amino acid transport and metabolism
- Q: Secondary metabolites biosynthesis, transport and catabolism
- T: Signal transduction mechanisms
| Gene Ontology |
|---|
| carboxypeptidase activity |
| hydrolase activity |
| metal ion binding |
| metallopeptidase activity |
| peptidyl-dipeptidase activity |
| proteolysis |
| InterPro |
|---|
| Peptidase M2, peptidyl-dipeptidase A |
Alliance of Genome Resources
- Expression
| Location | References |
|---|---|
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0050851 | glomerulosclerosis | |
| DOID:0050855 | renal fibrosis | |
| DOID:0060071 | pre-malignant neoplasm | |
| DOID:0110861 | autosomal recessive polycystic kidney disease | |
| DOID:0111128 | focal segmental glomerulosclerosis 1 | |
| DOID:10652 | Alzheimer's disease | |
| DOID:10763 | hypertension | |
| DOID:11476 | osteoporosis | |
| DOID:1184 | nephrotic syndrome | |
| DOID:12986 | leukostasis |
Ortholog
| Species | Gene ID | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|
| 109060366 | CYPCA113140 | ||
| 109099167 | CYPCA105584 | ||
| 109318963 | CROPO06668 | ||
| 113489137 | ATHCN20156 | ||
| 113584762 | ELEEL34648 | ||
| 114581443 | PODMU00436 | ||
| 114815136 | ORNAN03168 | ||
| 115059877 | ECHNA46481 | ||
| 115159185 | SALTR00316 | ||
| 115200950 | SALTR100933 |
