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MIRAGE
lipoprotein lipase
Summary
- Gene Symbol
-
- LPL
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Calcium
- Cell membrane
- Chylomicron
- Direct protein sequencing
- Disease variant
- Disulfide bond
- Extracellular matrix
- Glycoprotein
- Heparin-binding
- Hydrolase
- Hyperlipidemia
- Lipid degradation
- Lipoprotein
- Metal-binding
- Nitration
- Reference proteome
- Signal
- VLDL
- Proteins
| UniProt | Protein Name |
|---|---|
| P06858 |
|
| A0A1B1RVA9 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| positive regulation of chemokine (C-X-C motif) ligand 2 production |
GO Hierarchy
biological process
metabolic process [inference]
cellular process [inference]
response to stimulus [inference]
biological regulation [inference]
regulation of biological process [inference]
regulation of metabolic process [inference]
regulation of biosynthetic process [inference]
positive regulation of metabolic process [inference]
regulation of cellular metabolic process [inference]
regulation of macromolecule metabolic process [inference]
positive regulation of biological process [inference]
positive regulation of metabolic process [inference]
positive regulation of cellular process [inference]
regulation of developmental process [inference]
regulation of cellular process [inference]
regulation of cellular metabolic process [inference]
regulation of cell differentiation [inference]
positive regulation of cellular process [inference]
regulation of multicellular organismal process [inference]
| GO Term | Evidence Code | PMID |
|---|---|---|
| extracellular region | ||
| extracellular space | ||
| extracellular space | ||
| extracellular space | ||
| plasma membrane |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| lipoprotein lipase activity | ||
| lipoprotein lipase activity | ||
| lipoprotein lipase activity | ||
| lipoprotein lipase activity | ||
| phospholipase activity |
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- lipase I
- Functional Category
-
- I: Lipid transport and metabolism
- Q: Secondary metabolites biosynthesis, transport and catabolism
- T: Signal transduction mechanisms
| Gene Ontology |
|---|
| lipase activity |
| lipid metabolic process |
| InterPro |
|---|
| Alpha/Beta hydrolase fold |
| Lipase, N-terminal |
| Lipase |
| Triacylglycerol lipase family |
Rhea
Disease
- The Human Phenotype Ontology
| HPO ID | HPO Term |
|---|---|
| HP:0002013 | Vomiting |
| HP:0002018 | Nausea |
| HP:0002574 | Episodic abdominal pain |
| HP:0003077 | Hyperlipidemia |
| HP:0003124 | Hypercholesterolemia |
| HP:0003141 | Increased LDL cholesterol concentration |
| HP:0003362 | Increased VLDL cholesterol concentration |
| HP:0004416 | Precocious atherosclerosis |
| HP:0011462 | Young adult onset |
| HP:0012238 | Increased circulating chylomicron concentration |
| Disease ID | Disease Name |
|---|---|
| OMIM:144250 |
|
| OMIM:238600 |
|
PubChem Disease
- GHR Health Conditions
- MedGen Diseases
- OMIM Phenotypes
- KEGG Diseases
LIPID MAPS Gene / Proteome Database
- LMPD ID
- LMP002234
- Gene Name
- lipoprotein lipase
Ortholog
| Species | Gene ID | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|
| 3990 | FB:FBgn0265267 | ||
| 4023 | Xenbase:XB-GENE-951545 | ||
| 9388 | FB:FBgn0265267 | ||
| 15450 | FB:FBgn0038398 | ||
| 16891 | FB:FBgn0038398 | ||
| 16956 | Xenbase:XB-GENE-951545 | MOUSE58833 | |
| 18946 | FB:FBgn0034166 | ||
| 24539 | Xenbase:XB-GENE-951545 | RATNO11170 | |
| 30354 | DANRE23829 | ||
| 84028 | FB:FBgn0034166 |
