lysine methyltransferase 2A

Summary
Gene Symbol
  • KMT2A
Organism
Homo sapiens (human)
NCBI Gene
4297
PubChem
4297
Alliance of Genome Resources
Annotation
Keyword
  • 3D-structure
  • Acetylation
  • Alternative splicing
  • Apoptosis
  • Biological rhythms
  • Bromodomain
  • Chromatin regulator
  • Chromosomal rearrangement
  • DNA-binding
  • Direct protein sequencing
  • Host-virus interaction
  • Isopeptide bond
  • Methylation
  • Methyltransferase
  • Nucleus
  • Phosphoprotein
  • Proteomics identification
  • Proto-oncogene
  • Reference proteome
  • Repeat
  • S-adenosyl-L-methionine
  • Transcription regulation
  • Ubl conjugation
  • Zinc-finger
Proteins
Displaying all 2 entries
UniProt Protein Name
Q03164
  • ALL-1
  • CXXC-type zinc finger protein 7
  • Cysteine methyltransferase KMT2A
  • Myeloid/lymphoid or mixed-lineage leukemia
  • Myeloid/lymphoid or mixed-lineage leukemia protein 1
  • Trithorax-like protein
  • Zinc finger protein HRX
E9PR05
Gene Ontology (GO)
GO Hierarchy
GO Hierarchy
OrthoDB (Group)
Group level
Eukaryota
Group Name
Histone-lysine n-methyltransferase
Functional Category
  • C: Energy production and conversion
  • J: Translation, ribosomal structure and biogenesis
  • T: Signal transduction mechanisms
Displaying all 2 entries
Gene Ontology
methylation
transferase activity
Displaying all 3 entries
InterPro
Post-SET domain
SET domain superfamily
SET domain
Disease
Disease Ontology
Displaying all 8 entries
DO ID Disease Name Source
DOID:0060060 non-Hodgkin lymphoma
DOID:10283 prostate cancer
DOID:1682 congenital heart disease
DOID:224 transient cerebral ischemia
DOID:4362 cervical cancer
DOID:4971 myelofibrosis
DOID:9119 acute myeloid leukemia
DOID:9952 acute lymphoblastic leukemia

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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: December 9, 2024