GlyCosmos Portal

Displaying entries **1 - 5** of 7 in total

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GO Term	Evidence Code	PMID
DNA binding	IBA
DNA N-glycosylase activity	TAS
satellite DNA binding	TAS	9774669
pyrimidine-specific mismatch base pair DNA N-glycosylase activity	IDA	14614141
DNA endonuclease activity	TAS	10097147

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity [inference]

hydrolase activity, acting on ester bonds [inference]

nuclease activity [inference]

endonuclease activity [inference]

DNA endonuclease activity

DNA nuclease activity [inference]

DNA endonuclease activity

hydrolase activity, acting on glycosyl bonds [inference]

hydrolase activity, hydrolyzing N-glycosyl compounds [inference]

DNA N-glycosylase activity

mismatch base pair DNA N-glycosylase activity [inference]

pyrimidine-specific mismatch base pair DNA N-glycosylase activity

catalytic activity, acting on a nucleic acid [inference]

catalytic activity, acting on DNA [inference]

DNA nuclease activity [inference]

DNA endonuclease activity

DNA N-glycosylase activity

mismatch base pair DNA N-glycosylase activity [inference]

pyrimidine-specific mismatch base pair DNA N-glycosylase activity

binding [inference]

protein binding

organic cyclic compound binding [inference]

nucleic acid binding [inference]

DNA binding

double-stranded DNA binding [inference]

sequence-specific double-stranded DNA binding [inference]

satellite DNA binding

sequence-specific DNA binding [inference]

sequence-specific double-stranded DNA binding [inference]

satellite DNA binding

Gene Ontology information from NCBI Gene and UniProt.

Human Protein Atlas

ENSG00000129071

Tissue with high expression from Human Protein Atlas. Tissues that are highly expressed are highlighted.

Data available from v23.0.proteinatlas.org. Image credit: Human Protein Atlas

Disease

Disease Ontology

Displaying entries **61 - 70** of 71 in total

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DO ID	Disease Name	Source
DOID:684	hepatocellular carcinoma	DisGeNET
DOID:7148	rheumatoid arthritis	DisGeNET Alliance of Genome Resources
DOID:7693	abdominal aortic aneurysm	DisGeNET
DOID:8864	acute monocytic leukemia	DisGeNET
DOID:8924	autoimmune thrombocytopenic purpura	DisGeNET DisGeNET
DOID:8931	Evans' syndrome	DisGeNET
DOID:9074	systemic lupus erythematosus	DisGeNET
DOID:9119	acute myeloid leukemia	DisGeNET
DOID:9256	colorectal cancer	DisGeNET DisGeNET DisGeNET DisGeNET
DOID:9277	primary cerebellar degeneration	DisGeNET

The Human Phenotype Ontology

Displaying entries **1 - 10** of 11 in total

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HPO ID	HPO Term
HP:0000006	Autosomal dominant inheritance
HP:0002858	Meningioma
HP:0003003	Colon cancer
HP:0003581	Adult onset
HP:0003596	Middle age onset
HP:0003621	Juvenile onset
HP:0004808	Acute myeloid leukemia
HP:0005227	Adenomatous colonic polyposis
HP:0007716	Uveal melanoma
HP:0011462	Young adult onset

Displaying **all 2** entries
Disease ID	Disease Name
OMIM:619975	tumor predisposition syndrome 2
OMIM:606660	melanoma, uveal, susceptibility to, 1

PubChem Disease

MedGen Diseases

OMIM Phenotypes

KEGG Diseases

Tumor predisposition syndrome

Gene-Disease-Co-Occurrences-in-Literature (PubChem)

Ortholog

Displaying entries **1 - 10** of 44 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Danio rerio	101887128	ZFIN:ZDB-GENE-040213-1
Xenopus laevis	108714643	Xenbase:XB-GENE-6487015
Xenopus tropicalis	733528	Xenbase:XB-GENE-489215
Ornithorhynchus anatinus	100074449		ORNAN28005
Erinaceus europaeus	103108238		ERIEU11017
Cercocebus atys	105585848		CERAT02528
Macaca mulatta	720557		MACMU28014
Macaca nemestrina	105477770		MACNE19441
Mandrillus leucophaeus	105555322		MANLE36733
Gorilla gorilla gorilla	101134542		GORGO28609

ChIP-Atlas

Target Genes: Predicted target genes bound by given transcription factors. Target Genes
Potential target genes for MBD4
Distance from TSS: ± 10 kb

Displaying entries **11 - 20** of **148** in total

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Gene Symbol	Description	Cellline (score)
LCAT	lecithin-cholesterol acyltransferase	Hep_G2(109)
STT3B	STT3 oligosaccharyltransferase complex catalytic subunit B	Hep_G2(125)
PLD1	phospholipase D1	Hep_G2(235)
ALG14	ALG14 UDP-N-acetylglucosaminyltransferase subunit	Hep_G2(135)
PLA2G2A	phospholipase A2 group IIA	Hep_G2(131)
XXYLT1	xyloside xylosyltransferase 1	Hep_G2(102)
UGT2B7	UDP glucuronosyltransferase family 2 member B7	Hep_G2(125)
GDPD1	glycerophosphodiester phosphodiesterase domain containing 1	Hep_G2(113)
PLCD3	phospholipase C delta 3	Hep_G2(193)
MAN2A2	mannosidase alpha class 2A member 2	Hep_G2(93)

Colocalization: Predicted partner proteins colocalizing with given transcription factors. Colocalization
Colocalization analysis for MBD4

Displaying 1 entry
Gene Symbol	Description	Cellline (score)
MBD4	methyl-CpG binding domain 4, DNA glycosylase	Hep_G2(10)

An integrative, comprehensive database to explore public Epigenetic dataset, including ChIP-Seq, DNase-Seq, ATAC-Seq, and Bisulfite-Seq data: ChIP-Atlas covers almost all public data archived in Sequence Read Archive of NCBI, EBI, and DDBJ with over 224,000 experiments.

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

All Resources

Other Information

Tools

Search Tools

Summary

External Links

Annotation

PubChem Disease

International Collaboration

Acknowledgements