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MIRAGE
Interferon gamma

Summary
UniProt ID
P01579
Gene Symbol
  • IFNG
Gene ID
3458
Organism
Homo sapiens (human)
GlyConnect
GlyGen
P01579
PubChem
P01579
The Human Metabolome Database
HMDBP02071
Re-Glyco
P01579
Annotation
Keyword
  • 3D-structure
  • Antiviral defense
  • Cleavage on pair of basic residues
  • Cytokine
  • Direct protein sequencing
  • Glycoprotein
  • Growth regulation
  • Pharmaceutical
  • Pyrrolidone carboxylic acid
  • Reference proteome
  • Secreted
  • Signal
Gene Ontology (GO)
Displaying all 2 entries
GO Term
extracellular region
extracellular space
Subcellular Location(GO Annotation)

Subcellular in which this glycoprotein is expressed are highlighted in blue.

Displaying all 2 entries
GO Term
type II interferon receptor binding
cytokine activity
Annotation information from UniProt.
Sequence
MKYTSYILAFQLCIVLGSLGCYCQDPYVKEAENLKKYFNAGHSDVADNGTLFLGILKNWKEESDRKIMQSQIVSFYFKLFKNFKDDQSIQKSVETIKEDMNVKFFNSNKKKRDDFEKLTNYSVTDLNVQRKAIHELIQVMAELSPAAKTGKRKRSQMLFRGRRASQ
  • N : N-glycosylation Site
  • ___ : Potential Sequon
Glycosylation Sites
Displaying all 3 entries
Position Description PubMed ID GlyTouCan ID Source
48 N-linked (GlcNAc...) asparagine
120 N-linked (GlcNAc...) asparagine; in dimeric form
Feature
  • ProtVista GlyGen : Glycosylation Site from GlyGen
  • ProtVista UniProt : Glycosylation Site from UniProt
Pathway
Displaying all 5 entries
Pathway Name Organism
Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation Homo sapiens
IFNG signaling activates MAPKs Homo sapiens
Interferon gamma signaling Homo sapiens
RUNX1 and FOXP3 control the development of regulatory T lymphocytes (Tregs) Homo sapiens
Regulation of IFNG signaling Homo sapiens
Disease
Displaying entries 1 - 10 of 28 in total
DO ID Disease Name Source
DOID:0080162 lupus nephritis
DOID:0080325 tuberous sclerosis 2
DOID:0081267 graft-versus-host disease
DOID:0112006 immunodeficiency 69
DOID:10003 sensorineural hearing loss
DOID:12134 factor VIII deficiency
DOID:12306 vitiligo
DOID:12361 Graves' disease
DOID:12449 aplastic anemia
DOID:12704 ataxia telangiectasia
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International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: August 4, 2025