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MIRAGE
Cellular tumor antigen p53
Summary
- UniProt ID
- P02340
- Gene Symbol
-
- P53
- Tp53
- Trp53
- Gene ID
- 22059
- Organism
- Mus musculus (house mouse)
Annotation
- Keyword
-
- 3D-structure
- Acetylation
- Activator
- Apoptosis
- Biological rhythms
- Cell cycle
- Cytoskeleton
- DNA-binding
- Disease variant
- Endoplasmic reticulum
- Isopeptide bond
- Metal-binding
- Methylation
- Mitochondrion
- Necrosis
- Nucleus
- Phosphoprotein
- Reference proteome
- Repressor
- Transcription regulation
- Tumor suppressor
- Ubl conjugation
- Zinc
- Gene Ontology (GO)
| GO Term |
|---|
| chromatin |
| nucleus |
| nucleolus |
| cytoplasm |
| mitochondrion |
| mitochondrial matrix |
| nucleoplasm |
| endoplasmic reticulum |
| cytosol |
| replication fork |
Sequence
MTAMEESQSDISLELPLSQETFSGLWKLLPPEDILPSPHCMDDLLLPQDVEEFFEGPSEALRVSGAPAAQDPVTETPGPVAPAPATPWPLSSFVPSQKTYQGNYGFHLGFLQSGTAKSVMCTYSPPLNKLFCQLAKTCPVQLWVSATPPAGSRVRAMAIYKKSQHMTEVVRRCPHHERCSDGDGLAPPQHLIRVEGNLYPEYLEDRQTFRHSVVVPYEPPEAGSEYTTIHYKYMCNSSCMGGMNRRPILTIITLEDSSGNLLGRDSFEVRVCACPGRDRRTEEENFRKKEVLCPELPPGSAKRALPTCTSASPPQKKKPLDGEYFTLKIRGRKRFEMFRELNEALELKDAHATEESGDSRAHSSYLKTKKGQSTSRHKKTMVKKVGPDSD
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 86 |
|
|
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| RUNX3 regulates CDKN1A transcription | Mus musculus |
| Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks | Mus musculus |
| Regulation of TP53 Activity through Acetylation | Mus musculus |
| Regulation of TP53 Activity through Association with Co-factors | Mus musculus |
| Regulation of TP53 Activity through Methylation | Mus musculus |
| Regulation of TP53 Activity through Phosphorylation | Mus musculus |
| Regulation of TP53 Degradation | Mus musculus |
| Regulation of TP53 Expression | Mus musculus |
| Stabilization of p53 | Mus musculus |
| The role of GTSE1 in G2/M progression after G2 checkpoint | Mus musculus |
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0050745 | diffuse large B-cell lymphoma | |
| DOID:0050834 | CHARGE syndrome | |
| DOID:1380 | endometrial cancer | |
| DOID:1612 | breast cancer | |
| DOID:2729 | dyskeratosis congenita | |
| DOID:3012 | Li-Fraumeni syndrome | |
| DOID:3068 | glioblastoma | |
| DOID:3347 | osteosarcoma |
