Estrogen receptor
| GO Term |
|---|
| chromatin |
| euchromatin |
| nucleus |
| cytoplasm |
| plasma membrane |
| membrane |
| protein-containing complex |
| nucleoplasm |
| Golgi apparatus |
| cytosol |
| GO Term |
|---|
| negative regulation of transcription by RNA polymerase II |
| regulation of transcription by RNA polymerase II |
| positive regulation of cytosolic calcium ion concentration |
| male gonad development |
| GO Term |
|---|
| transcription coregulator binding |
| transcription corepressor binding |
| DNA-binding transcription activator activity, RNA polymerase II-specific |
| DNA-binding transcription factor activity |
| steroid binding |
| calmodulin binding |
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 10 | O-linked (GlcNAc) serine |
|
||
| 553 |
|
|||
| 554 |
|
|||
|
|
| Pathway Name | Organism |
|---|---|
| Constitutive Signaling by Aberrant PI3K in Cancer | Homo sapiens |
| ESR-mediated signaling | Homo sapiens |
| Estrogen-dependent gene expression | Homo sapiens |
| Extra-nuclear estrogen signaling | Homo sapiens |
| Mitochondrial unfolded protein response (UPRmt) | Homo sapiens |
| Nuclear Receptor transcription pathway | Homo sapiens |
| Nuclear signaling by ERBB4 | Homo sapiens |
| Ovarian tumor domain proteases | Homo sapiens |
| PI3K/AKT Signaling | Homo sapiens |
| PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling | Homo sapiens |
Tissue with high expression from Human Protein Atlas. Tissues that are highly expressed are highlighted.
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:10283 | prostate cancer | |
| DOID:10652 | Alzheimer's disease | |
| DOID:11476 | osteoporosis | |
| DOID:12306 | vitiligo | |
| DOID:1612 | breast cancer | |
| DOID:2349 | arteriosclerosis | |
| DOID:289 | endometriosis | |
| DOID:3393 | coronary artery disease | |
| DOID:3459 | breast carcinoma | |
| DOID:3908 | lung non-small cell carcinoma |
GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.
Supported by JST NBDC Grant Number JPMJND2204
Partly supported by NIH Common Fund Grant #1U01GM125267-01
This work is licensed under Creative Commons Attribution 4.0 International
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Last updated: December 8, 2025