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Low affinity immunoglobulin gamma Fc region receptor III-A

Summary

UniProt ID

P08637

Gene Symbol

FCGR3A
CD16A
FCG3
FCGR3
IGFR3

Organism

Homo sapiens (human)

External Links

GlyConnect

3000

GlyGen

P08637

PubChem

P08637

Annotation

Keyword

3D-structure
Cell membrane
Disulfide bond
Glycoprotein
IgG-binding protein
Immunity
Immunoglobulin domain
Phosphoprotein
Receptor
Reference proteome
Repeat
Secreted
Signal
Transmembrane helix

Gene Ontology (GO)

Displaying entries **1 - 10** of 12 in total

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GO Term
antibody-dependent cellular cytotoxicity
immune response
cell surface receptor signaling pathway
natural killer cell activation
macrophage activation
natural killer cell mediated cytotoxicity
calcium-mediated signaling
positive regulation of tumor necrosis factor production
positive regulation of natural killer cell proliferation
natural killer cell degranulation

Displaying **all 5** entries
GO Term
extracellular space
plasma membrane
Fc-gamma receptor III complex
external side of plasma membrane
extracellular exosome

Displaying **all 4** entries
GO Term
IgG receptor activity
low-affinity IgG receptor activity
IgG binding
immune receptor activity

Annotation information from UniProt.

Sequence

MWQLLLPTALLLLVSAGMRTEDLPKAVVFLEPQWYRVLEKDSVTLKCQGAYSPEDNSTQWFHNESLISSQASSYFIDAATVDDSGEYRCQTNLSTLSDPVQLEVHIGWLLLQAPRWVFKEEDPIHLRCHSWKNTALHKVTYLQNGKGRKYFHHNSDFYIPKATLKDSGSYFCRGLFGSKNVSSETVNITITQGLAVSTISSFFPPGYQVSFCLVMVLLFAVDTGLYFSVKTNIRSSTRDWKDHKFKWRKDPQDK

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 7** entries
Position	Description	PubMed ID	GlyTouCan ID	Source
56	N-linked (GlcNAc...) asparagine		G91152KU G16208YZ G28103WK G57581QG G48488CO	UniProt GlyGen GlyConnect
63	N-linked (GlcNAc...) asparagine	21768335 22023369	G64394MX G83295QG G31153XO G93656SY G13728QT G32246SI G81263BG G54982TL G08146BT G22310AV G16758MX G59536GA G82830MN G42358LZ G48414YA G25418HZ G45495MK G84452RH G72978AW G10773YW G06356OH G37868ZX G23294PN G61302NC G70101JE G98719SR G34730YF G84820NF G82463GQ G83624CJ G11870QZ G37442IW G44513XM G72291OX G21001NA G39188ZX G06110VR G45841FE	UniProt GlyGen GlyConnect
82				GlyGen
92	N-linked (GlcNAc...) asparagine		G91152KU G28103WK G57581QG G69834CE	UniProt GlyGen GlyConnect
180	N-linked (GlcNAc...) asparagine	21768335 22023369	G64394MX G83295QG G34617SM G37881RL G11629QQ G58232MG G86795LJ G32246SI G81263BG G08146BT G22310AV G02030ZB G75983OB G72797UR G72667IM G45495MK G84452RH G10773YW G71569SN G20218ZS G91636VS G44215PV G23294PN G61302NC G34730YF G23863VK G48390IG G84820NF G82463GQ G83624CJ G64527OM G67381VP G11870QZ G37442IW G23432EQ G55052CN G72735IY G44513XM G72291OX G05724UK G43947VZ G29880MM G68698AP G21001NA G39188ZX G06110VR G45841FE G74724QE G82348BZ	UniProt GlyGen GlyConnect
187	N-linked (GlcNAc...) asparagine		G91152KU G64394MX G83295QG G15169WU G34617SM G11629QQ G58232MG G32246SI G81263BG G08146BT G22310AV G45495MK G84452RH G14994KB G11870QZ G37442IW G94854LT G74724QE G82348BZ	UniProt GlyGen GlyConnect
			G62326NX G90093AU G26915XM G17689DH G22310AV G72797UR G63381RX G72667IM G84452RH G96095QD G25520XG G91636VS G93141AZ G70418MS G03382KH G90717TP G23863VK G78059CC G74430RZ G31916IQ G64527OM G23432EQ G72902CL G46687AB G62389NM G82119TF G72291OX G05724UK G29011JC G31936TA G49874UX G80858MF G39188ZX G39213VZ G06110VR G55220VL G60145BJ G96771UL	GlyGen GlyConnect

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying **all 6** entries
Pathway Name	Organism
FCGR activation	Homo sapiens
FCGR3A-mediated IL10 synthesis	Homo sapiens
FCGR3A-mediated phagocytosis	Homo sapiens
Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell	Homo sapiens
Regulation of actin dynamics for phagocytic cup formation	Homo sapiens
Role of phospholipids in phagocytosis	Homo sapiens

Human Protein Atlas

ENSG00000203747

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

All Resources

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Annotation