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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Poly [ADP-ribose] polymerase 1
Summary
- UniProt ID
- P11103
- Gene Symbol
-
- Parp1
- Adprp
- Adprt
- Adprt1
- Organism
- Mus musculus (house mouse)
Annotation
- Keyword
-
- ADP-ribosylation
- Acetylation
- Allosteric enzyme
- Alternative initiation
- Apoptosis
- Chromosome
- Cytoplasm
- DNA repair
- DNA-binding
- Direct protein sequencing
- Glycosyltransferase
- Innate immunity
- Isopeptide bond
- NAD
- Nucleotidyltransferase
- Nucleus
- Phosphoprotein
- Reference proteome
- Repeat
- S-nitrosylation
- Transcription regulation
- Ubl conjugation
- Zinc-finger
- Gene Ontology (GO)
| GO Term |
|---|
| chromatin |
| nucleus |
| nucleolus |
| cytoplasm |
| protein-containing complex |
| site of double-strand break |
| site of DNA damage |
| nuclear replication fork |
| mitochondrion |
| cytosol |
| GO Term |
|---|
| nucleotidyltransferase activity |
Sequence
MAEASERLYRVQYAKSGRASCKKCSESIPKDSLRMAIMVQSPMFDGKVPHWYHFSCFWKVGQSIRHPDVEVDGFSELRWDDQQKVKKTAEAGGVAGKGQDGSGGKAEKTLGDFAAEYAKSNRSMCKGCLEKIEKGQMRLSKKMVDPEKPQLGMIDRWYHPTCFVKKRDELGFRPEYSASQLKGFSLLSAEDKEALKKQLPAIKNEGKRKGDEVDGTDEVAKKKSRKETDKYSKLEKALKAQNELIWNIKDELKKACSTNDLKELLIFNQQQVPSGESAILDRVADGMAFGALLPCKECSGQLVFKSDAYYCTGDVTAWTKCMVKTQNPSRKEWVTPKEFREISYLKKLKVKKQDRIFPPESSAPITVHWPLSVTSAPTAVNSSAPADKPLSNMKILTLGKLSQNKDEAKAVIEKLGGKLTGSANKASLCISIKKEVEKMNKKMEEVKEANIRVVSEDFLQDVSASTKSLQDLLSAHSLSPWGAEVKAEPGEVVAPRGKSAAPSKKSKGCFKEEGVNKSEKRMKLTLKGGAAVDPDSGLEHSAHVLEKGGKVFSATLGLVDIVKGTNSYYKLQLLEDDKESRYWIFRSWGRLGTVIGSNKLEQMPSKEEAVEQFMKLYEEKTGNAWHSKNFTKYPKKFYPLEIDYGQDEEAVKKLTVKPGTKSKLPKPVQELVGMIFDVDSMKKALVEYEIDLQKMPLGKLSRRQIQAAYSILSEVQQPVSQGSSESQILDLSNRFYTLIPHDFGMKKPPLLNNADSVQAKVEMLDNLLDIEVAYSLLRGGSDDSSKDPIDVNYEKLKTDIKVVDRDSEEAEVIRKYVKNTHATTHNAYDLEVIDIFKIEREGESQRYKPFRQLHNRRLLWHGSRTTNFAGILSQGLRIAPPEAPVTGYMFGKGIYFADMVSKSANYCHTSQGDPIGLIMLGEVALGNMYELKHASHISKLPKGKHSVKGLGKTTPDPSASITLEGVEVPLGTGIPSGVNDTALLYNEYIVYDIAQVNLKYLLKLKFNFKTSLW
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 121 |
|
|||
|
|
G44613TH
G49108TO
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| DNA Damage Recognition in GG-NER | Mus musculus |
| Downregulation of SMAD2/3:SMAD4 transcriptional activity | Mus musculus |
| Dual Incision in GG-NER | Mus musculus |
| Formation of Incision Complex in GG-NER | Mus musculus |
| HDR through MMEJ (alt-NHEJ) | Mus musculus |
| POLB-Dependent Long Patch Base Excision Repair | Mus musculus |
| SUMOylation of DNA damage response and repair proteins | Mus musculus |
